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The map label for this gene is ffh [H]

Identifier: 213691304

GI number: 213691304

Start: 451341

End: 452993

Strand: Reverse

Name: ffh [H]

Synonym: Blon_0391

Alternate gene names: 213691304

Gene position: 452993-451341 (Counterclockwise)

Preceding gene: 213691306

Following gene: 213691303

Centisome position: 15.99

GC content: 64.49

Gene sequence:

>1653_bases
ATGGCAGCTTTTTCATCTTTGACAGACAGACTCTCGAATGCGTTCAAGCATCTCAAGAGCAAGGGCAAGCTTTCCGAGGC
GGATATCGACGGTACGATCCGTGAAATCCGCCGCGCGCTGCTCGACGCCGACGTGGCGCTCGACGTGGTGCGTTCCTTCA
CCGGCAAGGTGCGTGAGCGCGCACTGGGCACCGAGGTGTCCGACGCACTCAACCCCGCCCAACAGGTGGTGAAAATCGTC
AACGAGGAGCTCACCGACGTGCTCGGCCAAGGCGTCGATCGTCCGCTGAACTTCGCAAAGAACCCGCCGACGATCATCAT
GCTCGCCGGCCTTCAGGGTGCCGGTAAGACCACGCTGGCCGGCAAGCTCGGCTACTGGCTCAAGGAGTCCGGCCACACGC
CGCTGCTGGTGGCGGCCGATTTGCAGCGTCCGAACGCGGTGACGCAGCTGCAGGTGGTCGGCGAACGCGCCGGCGTGCCC
GTCTATGCTCCCGAAAAGGGCGTCCAATCCGATGGCGGCGAGGCCGTCGCAGCTCCGGGCCAGACCTCCGGCGACCCGGT
GAAGGTGGCCCGCGATTCCATCGAACTCGCGAGGCAGAAGCTCTACGACACGGTGATCATCGATACCGCCGGTCGTCTGG
GCGTGGACGAGGAGCTGATGAGGCAGGCCCGCGACATTCGCGATGCCGTGCAGCCGAATGAGATCCTGTTCGTCATCGAC
GCGATGATCGGCCAGGACGCCGTCAGGACCGCCAAGGCCTTTGACGAGGGCGTGGACTTCACCGGCGTGGTGCTGTCCAA
GCTCGATGGTGACGCCCGCGGTGGTGCCGCGTTGTCCGTGGCGTCCGTGACCGGCAAGCCGATCCTGTTCGCCTCCAATG
GCGAGGGGTTGAAGGACTTCGAGGTCTTCCACCCGGACCGTATGGCTTCGCGCATCCTCGACATGGGCGACATCATGACG
CTCATCGAACAGGCGCAGAAGCAGTTCGACGAGGAGGAGGCCCGCAAGGCCGCCGCGAAGATCTCCGATGGCTCCTTCGG
CCTGGACGATTTCCTCGATCAGCTGCAGCAGGTGCGCAAGCTGGGGTCGATGAAGTCCCTGCTCGGCATGATTCCGGGCA
TGGCCCAGCACCGCAAGGAACTCGAGCAGTTCGATGAGAAGGAAATCGACCGCACCGAGGCGATTATTCGCTCGATGACC
CCGGCCGAGCGCCGCGATCCGTCGATCATCAATGGTTCCCGCCGCGCCCGCATCGCCTATGGTTCCGGCGTGACGGTCTC
CCAGGTGAACGCTTTGCTGCAGCGTTTCGAGCAGGCCGCAAAGATGATGCGTCGCATGACCAACCGTGGCGGCATGGGCG
GCGGCATCCCCGGCTTCGGCGGCCCGGCTATGGGCGGCGGCAAGAAGAAGGGCAAGAACAAGAAGAAGGGCGGCAAATCC
GGCAATCCGATGAAGCGCGAGGCCGAGGAAAAGGCATTGCGCGACAAGCTGGCCGGCAAGTCCTCCGGTTCGACCGGCGG
TTCCGCCTTCGCCAAGAAGCCACAGAACCCGGCCCTGCCCGCCGGCCTTGAACAGATGATGGGCAACGTCGATGGTGGCA
CTGAACTGCCGCCGAACCTCGGCGGAGGCCTTGGCGGACTGTTCGGCCGCTGA

Upstream 100 bases:

>100_bases
CTGAATGCCCAACATCCCTGACTACTACGCGACACATTCCCCGGAAAGCGTCGTCCCCAACACCGCAATTTCCCGCGTGG
CGGCTAGACTGTTGCCCATT

Downstream 100 bases:

>100_bases
TCTCACAACTTGGCTCCCCTCGCAGAGGGGAGCCAAGTTATATCTCGGTTCAATTTGTATTTCGAAAGGAACTTCCATGA
CGACAATCCTCGGCGCGGTG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAAFSSLTDRLSNAFKHLKSKGKLSEADIDGTIREIRRALLDADVALDVVRSFTGKVRERALGTEVSDALNPAQQVVKIV
NEELTDVLGQGVDRPLNFAKNPPTIIMLAGLQGAGKTTLAGKLGYWLKESGHTPLLVAADLQRPNAVTQLQVVGERAGVP
VYAPEKGVQSDGGEAVAAPGQTSGDPVKVARDSIELARQKLYDTVIIDTAGRLGVDEELMRQARDIRDAVQPNEILFVID
AMIGQDAVRTAKAFDEGVDFTGVVLSKLDGDARGGAALSVASVTGKPILFASNGEGLKDFEVFHPDRMASRILDMGDIMT
LIEQAQKQFDEEEARKAAAKISDGSFGLDDFLDQLQQVRKLGSMKSLLGMIPGMAQHRKELEQFDEKEIDRTEAIIRSMT
PAERRDPSIINGSRRARIAYGSGVTVSQVNALLQRFEQAAKMMRRMTNRGGMGGGIPGFGGPAMGGGKKKGKNKKKGGKS
GNPMKREAEEKALRDKLAGKSSGSTGGSAFAKKPQNPALPAGLEQMMGNVDGGTELPPNLGGGLGGLFGR

Sequences:

>Translated_550_residues
MAAFSSLTDRLSNAFKHLKSKGKLSEADIDGTIREIRRALLDADVALDVVRSFTGKVRERALGTEVSDALNPAQQVVKIV
NEELTDVLGQGVDRPLNFAKNPPTIIMLAGLQGAGKTTLAGKLGYWLKESGHTPLLVAADLQRPNAVTQLQVVGERAGVP
VYAPEKGVQSDGGEAVAAPGQTSGDPVKVARDSIELARQKLYDTVIIDTAGRLGVDEELMRQARDIRDAVQPNEILFVID
AMIGQDAVRTAKAFDEGVDFTGVVLSKLDGDARGGAALSVASVTGKPILFASNGEGLKDFEVFHPDRMASRILDMGDIMT
LIEQAQKQFDEEEARKAAAKISDGSFGLDDFLDQLQQVRKLGSMKSLLGMIPGMAQHRKELEQFDEKEIDRTEAIIRSMT
PAERRDPSIINGSRRARIAYGSGVTVSQVNALLQRFEQAAKMMRRMTNRGGMGGGIPGFGGPAMGGGKKKGKNKKKGGKS
GNPMKREAEEKALRDKLAGKSSGSTGGSAFAKKPQNPALPAGLEQMMGNVDGGTELPPNLGGGLGGLFGR
>Mature_549_residues
AAFSSLTDRLSNAFKHLKSKGKLSEADIDGTIREIRRALLDADVALDVVRSFTGKVRERALGTEVSDALNPAQQVVKIVN
EELTDVLGQGVDRPLNFAKNPPTIIMLAGLQGAGKTTLAGKLGYWLKESGHTPLLVAADLQRPNAVTQLQVVGERAGVPV
YAPEKGVQSDGGEAVAAPGQTSGDPVKVARDSIELARQKLYDTVIIDTAGRLGVDEELMRQARDIRDAVQPNEILFVIDA
MIGQDAVRTAKAFDEGVDFTGVVLSKLDGDARGGAALSVASVTGKPILFASNGEGLKDFEVFHPDRMASRILDMGDIMTL
IEQAQKQFDEEEARKAAAKISDGSFGLDDFLDQLQQVRKLGSMKSLLGMIPGMAQHRKELEQFDEKEIDRTEAIIRSMTP
AERRDPSIINGSRRARIAYGSGVTVSQVNALLQRFEQAAKMMRRMTNRGGMGGGIPGFGGPAMGGGKKKGKNKKKGGKSG
NPMKREAEEKALRDKLAGKSSGSTGGSAFAKKPQNPALPAGLEQMMGNVDGGTELPPNLGGGLGGLFGR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=475, Percent_Identity=30.9473684210526, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI226371618, Length=413, Percent_Identity=32.4455205811138, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI89061728, Length=154, Percent_Identity=38.961038961039, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI23308697, Length=308, Percent_Identity=28.2467532467532, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI295424842, Length=308, Percent_Identity=28.2467532467532, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1788963, Length=437, Percent_Identity=46.9107551487414, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1789874, Length=270, Percent_Identity=35.5555555555556, Blast_Score=145, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=463, Percent_Identity=28.9416846652268, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI193206261, Length=305, Percent_Identity=30.1639344262295, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=458, Percent_Identity=31.8777292576419, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6320498, Length=319, Percent_Identity=26.3322884012539, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17647949, Length=459, Percent_Identity=30.5010893246187, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24641198, Length=323, Percent_Identity=26.3157894736842, Blast_Score=109, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 58557; Mature: 58426

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFSSLTDRLSNAFKHLKSKGKLSEADIDGTIREIRRALLDADVALDVVRSFTGKVRER
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGTEVSDALNPAQQVVKIVNEELTDVLGQGVDRPLNFAKNPPTIIMLAGLQGAGKTTLA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHH
GKLGYWLKESGHTPLLVAADLQRPNAVTQLQVVGERAGVPVYAPEKGVQSDGGEAVAAPG
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCC
QTSGDPVKVARDSIELARQKLYDTVIIDTAGRLGVDEELMRQARDIRDAVQPNEILFVID
CCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHH
AMIGQDAVRTAKAFDEGVDFTGVVLSKLDGDARGGAALSVASVTGKPILFASNGEGLKDF
HHHCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHH
EVFHPDRMASRILDMGDIMTLIEQAQKQFDEEEARKAAAKISDGSFGLDDFLDQLQQVRK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGSMKSLLGMIPGMAQHRKELEQFDEKEIDRTEAIIRSMTPAERRDPSIINGSRRARIAY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEE
GSGVTVSQVNALLQRFEQAAKMMRRMTNRGGMGGGIPGFGGPAMGGGKKKGKNKKKGGKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GNPMKREAEEKALRDKLAGKSSGSTGGSAFAKKPQNPALPAGLEQMMGNVDGGTELPPNL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
GGGLGGLFGR
CCCCCCCCCC
>Mature Secondary Structure 
AAFSSLTDRLSNAFKHLKSKGKLSEADIDGTIREIRRALLDADVALDVVRSFTGKVRER
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGTEVSDALNPAQQVVKIVNEELTDVLGQGVDRPLNFAKNPPTIIMLAGLQGAGKTTLA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHH
GKLGYWLKESGHTPLLVAADLQRPNAVTQLQVVGERAGVPVYAPEKGVQSDGGEAVAAPG
HHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCC
QTSGDPVKVARDSIELARQKLYDTVIIDTAGRLGVDEELMRQARDIRDAVQPNEILFVID
CCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHH
AMIGQDAVRTAKAFDEGVDFTGVVLSKLDGDARGGAALSVASVTGKPILFASNGEGLKDF
HHHCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHH
EVFHPDRMASRILDMGDIMTLIEQAQKQFDEEEARKAAAKISDGSFGLDDFLDQLQQVRK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LGSMKSLLGMIPGMAQHRKELEQFDEKEIDRTEAIIRSMTPAERRDPSIINGSRRARIAY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEEE
GSGVTVSQVNALLQRFEQAAKMMRRMTNRGGMGGGIPGFGGPAMGGGKKKGKNKKKGGKS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GNPMKREAEEKALRDKLAGKSSGSTGGSAFAKKPQNPALPAGLEQMMGNVDGGTELPPNL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
GGGLGGLFGR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]