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The map label for this gene is cysS [H]

Identifier: 213691306

GI number: 213691306

Start: 454225

End: 455874

Strand: Reverse

Name: cysS [H]

Synonym: Blon_0393

Alternate gene names: 213691306

Gene position: 455874-454225 (Counterclockwise)

Preceding gene: 213691309

Following gene: 213691304

Centisome position: 16.09

GC content: 64.55

Gene sequence:

>1650_bases
ATGGGAAACAGCCAAGAACCGCAGGATTTCAACATTTCCGTCATGCCTTCAAGCCTGACGCCGATACATGTTGCCAAGGC
CGCAGAAGGCCTGAATCTGTATGACACCGCCTCGCACCAGGTCAGCCATTTCGTGCCGCTCAAGCCGGGCGAAGTCGGCA
TTTATGTGTGTGGCGCGACTGTGCAGTCGTCACCGCATATCGGCCATATCCGTGCCGCCGTGGCGTTCGACATCGTGCGC
CGCTGGTTTTTGAAGCTCGGCTACAAAGTCACTTTTGTGCGTAATGTGACCGATATCGACGACAAGATCCTCGATAAGGC
CGCGGCCGCCGGCCAGCGTTGGTGGGCCCGCGCCTATTATTACGAGCGCGAATTCACCGAGGCGTACAACACGCTCGGCG
TACTGCCGCCCACCGTGGAACCTCGCGCCACCGGCCACATGTCGGACATGATCGACCTGATTCAGCGCATTCTCGACAAC
GGCCACGGCTATGTGGTCACGGATGCGGACGGCAAGCCCACCGGCAACGTGTACTTCGATGTGGCATCCTGGCCGCATTA
CGGCGAACTCACCCACCAGAAGCAGACCTCCGAAGTCGATGAGGCCGCCGCCGTGGCCGACCGCATGGGCCCGTCCGTGG
ACGCCACCGGTGCCGACAAGTACAATCCGGTCGACCCGGCCGACGCCTCCCCCGACAAGCACGACCCGCGTGATTTCGCC
CTGTGGAAGGCCCCCAAGGACACCGATCCCGAGGACGCCCGTTGGTCGACGCCGTTCGGCGTGGGTCGCCCTGGCTGGCA
CATCGAATGCTCCGCCATGTCCCACCGTTACCTGGGCGATGGCTTCGACATTCACGGCGGCGGTTTGGATCTGCGCTTCC
CCCACCACGAAAACGAGATGGCGCAGACCTGCGCGGCCGGCTACCCCTCTGCTGCGCGCTGGATGCATTCGGCATGGGTG
ACCGCCAAGGGCGAGAAGATGTCGAAGTCGCTGGGCACCGGCCTGTCCGTGCCGAGCGTGCTGGCCGAGCATTCCGCTTG
GGTGGTGCGTTACGCTTTGGGCTCCGTGCAGTACCGGTCGATGCTCGAATGGTCCGATCAGGCGCTGGTCGAGGCGCAGG
CCGCATACGACCGCGTCTCGAACTTCATCGAACGAGCCGGCGTGGCACTGGGCGGTCAGCCTTCTCGCGAGGAGGTTGCT
GCCGTCTCCGCCGACGACCTGCCCGCTGATTTCGTGGCCGCCATGAATGACGACGTCAATGTGTCTGGTGCAACCGCCGC
GATCTTCACCGCCATCCGTTCCGGCAACACGTTGCTTTCACAGCTGGCTGACCGCGCCGATTCCGAAACCGCCAAGGCCG
AGGTGCGTGAGGCGCTGCTCGCCGTGCGTGCCATGCTCGACACCTTGGGTCTCGACCCGCTGGCCGAACCGTGGGTGTCC
GCCGGCGTTGCCGGCGGTGCCGCTGATGGCACGGCCGAGTCACCCGAACATGCGGCGCTGGAGGCACTGATTGCCGAGCA
GCTCAACGCCCGCGCCGAGGCCCGCAAGGCCAAGGACTTCGTCAAGGCCGACCAGATTCGCGACGCCCTGACCGAGGCCG
GCATCGCCATCGAAGACGGCCCGCAGGGTTCCACTTGGAGCCTGAAGTAG

Upstream 100 bases:

>100_bases
ATCCGTCTGTCACCTCGTTCGGGCCCCGCCTGTGAAGCGTTCATCAAACTCTTCGAGTAACGATTCAGCATGTCTGGTTC
GGACCCTACGCTTGAGTGTT

Downstream 100 bases:

>100_bases
CCGCTTCAAACCCATCAATCAGTCAAACACGAAGTCCACGTCCACGATGTGCAGGCGCTTGATGAGCTCCTTCTCCAGCG
AGCGCTTGCATTCGATGAGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MGNSQEPQDFNISVMPSSLTPIHVAKAAEGLNLYDTASHQVSHFVPLKPGEVGIYVCGATVQSSPHIGHIRAAVAFDIVR
RWFLKLGYKVTFVRNVTDIDDKILDKAAAAGQRWWARAYYYEREFTEAYNTLGVLPPTVEPRATGHMSDMIDLIQRILDN
GHGYVVTDADGKPTGNVYFDVASWPHYGELTHQKQTSEVDEAAAVADRMGPSVDATGADKYNPVDPADASPDKHDPRDFA
LWKAPKDTDPEDARWSTPFGVGRPGWHIECSAMSHRYLGDGFDIHGGGLDLRFPHHENEMAQTCAAGYPSAARWMHSAWV
TAKGEKMSKSLGTGLSVPSVLAEHSAWVVRYALGSVQYRSMLEWSDQALVEAQAAYDRVSNFIERAGVALGGQPSREEVA
AVSADDLPADFVAAMNDDVNVSGATAAIFTAIRSGNTLLSQLADRADSETAKAEVREALLAVRAMLDTLGLDPLAEPWVS
AGVAGGAADGTAESPEHAALEALIAEQLNARAEARKAKDFVKADQIRDALTEAGIAIEDGPQGSTWSLK

Sequences:

>Translated_549_residues
MGNSQEPQDFNISVMPSSLTPIHVAKAAEGLNLYDTASHQVSHFVPLKPGEVGIYVCGATVQSSPHIGHIRAAVAFDIVR
RWFLKLGYKVTFVRNVTDIDDKILDKAAAAGQRWWARAYYYEREFTEAYNTLGVLPPTVEPRATGHMSDMIDLIQRILDN
GHGYVVTDADGKPTGNVYFDVASWPHYGELTHQKQTSEVDEAAAVADRMGPSVDATGADKYNPVDPADASPDKHDPRDFA
LWKAPKDTDPEDARWSTPFGVGRPGWHIECSAMSHRYLGDGFDIHGGGLDLRFPHHENEMAQTCAAGYPSAARWMHSAWV
TAKGEKMSKSLGTGLSVPSVLAEHSAWVVRYALGSVQYRSMLEWSDQALVEAQAAYDRVSNFIERAGVALGGQPSREEVA
AVSADDLPADFVAAMNDDVNVSGATAAIFTAIRSGNTLLSQLADRADSETAKAEVREALLAVRAMLDTLGLDPLAEPWVS
AGVAGGAADGTAESPEHAALEALIAEQLNARAEARKAKDFVKADQIRDALTEAGIAIEDGPQGSTWSLK
>Mature_548_residues
GNSQEPQDFNISVMPSSLTPIHVAKAAEGLNLYDTASHQVSHFVPLKPGEVGIYVCGATVQSSPHIGHIRAAVAFDIVRR
WFLKLGYKVTFVRNVTDIDDKILDKAAAAGQRWWARAYYYEREFTEAYNTLGVLPPTVEPRATGHMSDMIDLIQRILDNG
HGYVVTDADGKPTGNVYFDVASWPHYGELTHQKQTSEVDEAAAVADRMGPSVDATGADKYNPVDPADASPDKHDPRDFAL
WKAPKDTDPEDARWSTPFGVGRPGWHIECSAMSHRYLGDGFDIHGGGLDLRFPHHENEMAQTCAAGYPSAARWMHSAWVT
AKGEKMSKSLGTGLSVPSVLAEHSAWVVRYALGSVQYRSMLEWSDQALVEAQAAYDRVSNFIERAGVALGGQPSREEVAA
VSADDLPADFVAAMNDDVNVSGATAAIFTAIRSGNTLLSQLADRADSETAKAEVREALLAVRAMLDTLGLDPLAEPWVSA
GVAGGAADGTAESPEHAALEALIAEQLNARAEARKAKDFVKADQIRDALTEAGIAIEDGPQGSTWSLK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=548, Percent_Identity=30.6569343065693, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI10835051, Length=446, Percent_Identity=31.1659192825112, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI21269877, Length=446, Percent_Identity=31.1659192825112, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI303304987, Length=446, Percent_Identity=31.1659192825112, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI62240992, Length=446, Percent_Identity=31.1659192825112, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1786737, Length=520, Percent_Identity=40.1923076923077, Blast_Score=332, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI17509795, Length=448, Percent_Identity=26.1160714285714, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509797, Length=448, Percent_Identity=26.1160714285714, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324082, Length=448, Percent_Identity=29.2410714285714, Blast_Score=167, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19922218, Length=545, Percent_Identity=30.8256880733945, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI19922364, Length=464, Percent_Identity=29.3103448275862, Blast_Score=155, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 59223; Mature: 59092

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSQEPQDFNISVMPSSLTPIHVAKAAEGLNLYDTASHQVSHFVPLKPGEVGIYVCGAT
CCCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHEEECCCCCCEEEEEECCE
VQSSPHIGHIRAAVAFDIVRRWFLKLGYKVTFVRNVTDIDDKILDKAAAAGQRWWARAYY
ECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
YEREFTEAYNTLGVLPPTVEPRATGHMSDMIDLIQRILDNGHGYVVTDADGKPTGNVYFD
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
VASWPHYGELTHQKQTSEVDEAAAVADRMGPSVDATGADKYNPVDPADASPDKHDPRDFA
ECCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LWKAPKDTDPEDARWSTPFGVGRPGWHIECSAMSHRYLGDGFDIHGGGLDLRFPHHENEM
EECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEECCCCEEEECCCCCHHH
AQTCAAGYPSAARWMHSAWVTAKGEKMSKSLGTGLSVPSVLAEHSAWVVRYALGSVQYRS
HHHHHCCCCHHHHHHHHHHEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLEWSDQALVEAQAAYDRVSNFIERAGVALGGQPSREEVAAVSADDLPADFVAAMNDDVN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEECCCCCCHHHHHHCCCCCC
VSGATAAIFTAIRSGNTLLSQLADRADSETAKAEVREALLAVRAMLDTLGLDPLAEPWVS
CCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGVAGGAADGTAESPEHAALEALIAEQLNARAEARKAKDFVKADQIRDALTEAGIAIEDG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
PQGSTWSLK
CCCCCCCCC
>Mature Secondary Structure 
GNSQEPQDFNISVMPSSLTPIHVAKAAEGLNLYDTASHQVSHFVPLKPGEVGIYVCGAT
CCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCCHHHHEEECCCCCCEEEEEECCE
VQSSPHIGHIRAAVAFDIVRRWFLKLGYKVTFVRNVTDIDDKILDKAAAAGQRWWARAYY
ECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
YEREFTEAYNTLGVLPPTVEPRATGHMSDMIDLIQRILDNGHGYVVTDADGKPTGNVYFD
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
VASWPHYGELTHQKQTSEVDEAAAVADRMGPSVDATGADKYNPVDPADASPDKHDPRDFA
ECCCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
LWKAPKDTDPEDARWSTPFGVGRPGWHIECSAMSHRYLGDGFDIHGGGLDLRFPHHENEM
EECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEECCCCEEEECCCCCHHH
AQTCAAGYPSAARWMHSAWVTAKGEKMSKSLGTGLSVPSVLAEHSAWVVRYALGSVQYRS
HHHHHCCCCHHHHHHHHHHEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLEWSDQALVEAQAAYDRVSNFIERAGVALGGQPSREEVAAVSADDLPADFVAAMNDDVN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEECCCCCCHHHHHHCCCCCC
VSGATAAIFTAIRSGNTLLSQLADRADSETAKAEVREALLAVRAMLDTLGLDPLAEPWVS
CCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGVAGGAADGTAESPEHAALEALIAEQLNARAEARKAKDFVKADQIRDALTEAGIAIEDG
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
PQGSTWSLK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]