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The map label for this gene is ribD [H]

Identifier: 213691299

GI number: 213691299

Start: 446659

End: 447759

Strand: Direct

Name: ribD [H]

Synonym: Blon_0386

Alternate gene names: 213691299

Gene position: 446659-447759 (Clockwise)

Preceding gene: 213691298

Following gene: 213691300

Centisome position: 15.77

GC content: 62.94

Gene sequence:

>1101_bases
ATGGACGATGCGCAGTACATGGGACTCGCGATCGAGCTGGCGAAGCGAGGGGCCGGATACGTGAACCCCAATCCCATGGT
CGGCGCGGTGATCGTCAAGGACGATCGGATCATCGGGCAGGGGTATCACGAGATGTTCGGCGGATTGCACGCCGAGAGGA
ACGCGTTGCGGCATTGCACGCAGTCACCCGCCGGGGCGACGTTGTACGTCACGCTTGAGCCGTGCTGCCATTACGGCAAA
ACGCCGCCATGCACGGAGGCGATCGTGGAAAGCGGCATCGCAAGGGTCGTCGTCGGAACCTTGGACTGCAATCCCGTGGT
GTCCGGCAAGGGCGTGCGCATGCTCGAAGACCACGGCATACGGGTCGATGTGGGGGTGCTGGCCGACGAGTGCCGGCATC
TGATACGGGTGTTCAGCAAATACATCACCACGCATACGCCGTATGTCATCATGAAATACGCCATGACGATGGACGGGAAG
ATAGCGACCCATACCAATCAATCACGGTGGATCAGCGGCGAGGAGTCGAGGCGTCGGGTCCATCAGCTCCGTCGATCCGT
CGCGGCGGTCATGGTGGGGGTGAACACGGTGATCGAGGACGACCCGTTGCTGACATGCCGCATGGCACACGGAAGGAACC
CGGTTCGCGTCGTCTGCGATACGCGATTGAGGACGCCCCTCACCTCGCGGATCGTGCAGACGGCGAATGACGTCAGGACC
TATATCGCCACCGCCTGCGATGACGAACGCAAGGCGGAGGACTACCGGCGGCACGGCTGCGAAATACTCGCCGTCGGAAG
GAAGGGCGACCACGTCGATCTGGCGGACGTGGTGCGGCGCCTGGGGGATATGCAGATGGACAGCGTGCTGCTGGAAGGCG
GGAGCGCGATGAATTGGAGCGCCCTCGAACAGCGGATCGTCGATGAGGCGCACGTGTACATCGCGCCGAAGATATTCGGC
GGCACCGCGAAAAGCCCGGTGGGCGGCCAAGGGGTCGCCCTGCCTTCCGACGCCGTCATGCTCCGGCCCCGCGCCTGCTC
CCGAGTGGGAGAGGATTATCTGGTGGAAAGCGAGGTGGTGTATTCATGTTCACGGGAATAG

Upstream 100 bases:

>100_bases
TGAAATGATGCCATATCATTTCAGGGCGTTTTCGTGTTCGCATGAACCTTCTTTTGTATGCCTTGGATAGCGTATGGGCG
CAACATGCTTGGAGGCGTAC

Downstream 100 bases:

>100_bases
TGGAGGAAGTCGGAACGGTGGCGGACATACGGAGGAGCGCCGCCAACTGCACGCTGTCGGTCGATGCCACGAACGTGATG
GAGGACCTCCATATCGGCGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MDDAQYMGLAIELAKRGAGYVNPNPMVGAVIVKDDRIIGQGYHEMFGGLHAERNALRHCTQSPAGATLYVTLEPCCHYGK
TPPCTEAIVESGIARVVVGTLDCNPVVSGKGVRMLEDHGIRVDVGVLADECRHLIRVFSKYITTHTPYVIMKYAMTMDGK
IATHTNQSRWISGEESRRRVHQLRRSVAAVMVGVNTVIEDDPLLTCRMAHGRNPVRVVCDTRLRTPLTSRIVQTANDVRT
YIATACDDERKAEDYRRHGCEILAVGRKGDHVDLADVVRRLGDMQMDSVLLEGGSAMNWSALEQRIVDEAHVYIAPKIFG
GTAKSPVGGQGVALPSDAVMLRPRACSRVGEDYLVESEVVYSCSRE

Sequences:

>Translated_366_residues
MDDAQYMGLAIELAKRGAGYVNPNPMVGAVIVKDDRIIGQGYHEMFGGLHAERNALRHCTQSPAGATLYVTLEPCCHYGK
TPPCTEAIVESGIARVVVGTLDCNPVVSGKGVRMLEDHGIRVDVGVLADECRHLIRVFSKYITTHTPYVIMKYAMTMDGK
IATHTNQSRWISGEESRRRVHQLRRSVAAVMVGVNTVIEDDPLLTCRMAHGRNPVRVVCDTRLRTPLTSRIVQTANDVRT
YIATACDDERKAEDYRRHGCEILAVGRKGDHVDLADVVRRLGDMQMDSVLLEGGSAMNWSALEQRIVDEAHVYIAPKIFG
GTAKSPVGGQGVALPSDAVMLRPRACSRVGEDYLVESEVVYSCSRE
>Mature_366_residues
MDDAQYMGLAIELAKRGAGYVNPNPMVGAVIVKDDRIIGQGYHEMFGGLHAERNALRHCTQSPAGATLYVTLEPCCHYGK
TPPCTEAIVESGIARVVVGTLDCNPVVSGKGVRMLEDHGIRVDVGVLADECRHLIRVFSKYITTHTPYVIMKYAMTMDGK
IATHTNQSRWISGEESRRRVHQLRRSVAAVMVGVNTVIEDDPLLTCRMAHGRNPVRVVCDTRLRTPLTSRIVQTANDVRT
YIATACDDERKAEDYRRHGCEILAVGRKGDHVDLADVVRRLGDMQMDSVLLEGGSAMNWSALEQRIVDEAHVYIAPKIFG
GTAKSPVGGQGVALPSDAVMLRPRACSRVGEDYLVESEVVYSCSRE

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=365, Percent_Identity=36.986301369863, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI145693172, Length=148, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40235; Mature: 40235

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDAQYMGLAIELAKRGAGYVNPNPMVGAVIVKDDRIIGQGYHEMFGGLHAERNALRHCT
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEECCCHHHHHCCHHHHHHHHHHHC
QSPAGATLYVTLEPCCHYGKTPPCTEAIVESGIARVVVGTLDCNPVVSGKGVRMLEDHGI
CCCCCEEEEEEECHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEECCCC
RVDVGVLADECRHLIRVFSKYITTHTPYVIMKYAMTMDGKIATHTNQSRWISGEESRRRV
EEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCEEEECCCCCCCCCCHHHHHHH
HQLRRSVAAVMVGVNTVIEDDPLLTCRMAHGRNPVRVVCDTRLRTPLTSRIVQTANDVRT
HHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
YIATACDDERKAEDYRRHGCEILAVGRKGDHVDLADVVRRLGDMQMDSVLLEGGSAMNWS
HHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCCHH
ALEQRIVDEAHVYIAPKIFGGTAKSPVGGQGVALPSDAVMLRPRACSRVGEDYLVESEVV
HHHHHHHCCCEEEEEEEEECCCCCCCCCCCCEECCCCCEEECCHHHHHCCHHHEECHHHH
YSCSRE
HHCCCC
>Mature Secondary Structure
MDDAQYMGLAIELAKRGAGYVNPNPMVGAVIVKDDRIIGQGYHEMFGGLHAERNALRHCT
CCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEECCCHHHHHCCHHHHHHHHHHHC
QSPAGATLYVTLEPCCHYGKTPPCTEAIVESGIARVVVGTLDCNPVVSGKGVRMLEDHGI
CCCCCEEEEEEECHHHCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEECCCC
RVDVGVLADECRHLIRVFSKYITTHTPYVIMKYAMTMDGKIATHTNQSRWISGEESRRRV
EEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCEEEECCCCCCCCCCHHHHHHH
HQLRRSVAAVMVGVNTVIEDDPLLTCRMAHGRNPVRVVCDTRLRTPLTSRIVQTANDVRT
HHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
YIATACDDERKAEDYRRHGCEILAVGRKGDHVDLADVVRRLGDMQMDSVLLEGGSAMNWS
HHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCCHH
ALEQRIVDEAHVYIAPKIFGGTAKSPVGGQGVALPSDAVMLRPRACSRVGEDYLVESEVV
HHHHHHHCCCEEEEEEEEECCCCCCCCCCCCEECCCCCEEECCHHHHHCCHHHEECHHHH
YSCSRE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]