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The map label for this gene is pabB [H]

Identifier: 213691298

GI number: 213691298

Start: 445025

End: 446419

Strand: Direct

Name: pabB [H]

Synonym: Blon_0385

Alternate gene names: 213691298

Gene position: 445025-446419 (Clockwise)

Preceding gene: 213691297

Following gene: 213691299

Centisome position: 15.71

GC content: 66.02

Gene sequence:

>1395_bases
GTGAGCGCGCAGGTGTTCAAGCTCAGGACGTTCCGACCGCTTGCCGACATCGTGGAGCGCGTGCGCGGCGAGGAACGCTT
CGCGTTCCTGGACTCCTCGATGCCGGGGGCGCAGGGGCGCTACTCGATCCTGGGACTCTTCCCCTATCTTGTGATCGAAC
ATGGGCGGGGCGGATGCCTCGTCGACGGCGTTGCCGTGGAGGGTGATTTCTTCGATGTCGTGAAGAAGCGGCTTGGACCC
TGCGATGGCGCGCGCGATCCGCGTCTGCCCCTCACGGGAGGCGCGATCGGGTATCTGGGATACGATTTCGGCCGCGAATC
GTGCGGCGTGCCGACCAGGCACGATCCCGTCGCGGCCACACCGGAGGCGAGCATGGTCTTCTACGACCTGCTACTCATCG
AGGACGTCCGGTCGCGGGCGTTGTTCTGTTGCTGCCAGGGGCGGACGATGACGGCCGCCCACGCCCTGACATGGGCGCAG
GACCTGGTGGATTCATGCCCTCCCGCCCCTCATCCCGCGCGCCGACGTTCGCTCGCCCCATGCTCCTCCGATTTCACGCG
GGCCGGGTACGGCGACGCCCTGGCCCGTCTCGTCGATCATCTGCGCGCCGGCGACGCCTACGTCGTCAACATGGCGCAGC
GCCTGCGCCTGGAGACGTCCGAGAGCCCCTATGCCATCTACCGTTATCTGCGCACCCACAACCCGGCCCCGTTTTCCGCC
TATCTGCGCGCGCCGGGTCTCGACGTGTGCTGTTCGAGCATGGAACGGTTCATGGAGATTCGCTCGGGGCATGTGGTGAC
GCGGCCCATCAAAGGGACCCGGCCGCGCGGCGGCACGCCGGACGAGGATCGGGCGAACCGCGAGGAACTCGCCCGCAGCG
AGAAGGACCACAGCGAACTGCTGATGGTCGTGGACCTCGAACGCAACGACCTGTCGATCGTCTGCGAACCGGGTTCCGTC
GGCACGGACCCCGACTTTGCCATCGAGACGTATCCTTCCGTATTCCATCTCGTCGCGACCGTCGAGGGGACGCTGCGCAA
GGATCGTTGCGCCGTGGACGCGGTTCGCGCCGCGTTTCCCACCGGTTCGATCACCGGCGCCCCGAAGGTTCGCGCCATGC
AGATCATCGACGAGCTCGAACGCGCGCCCCGGGGATTGTACACGGGCAGCATCGGGTATTTCTCCGATACGGGCGATTGC
GATTTCAACGTCGTGATCCGCACCATCGTGAGGGAGGGAGGCGAGACGTCGCTCGGCGTGGGCGGAGGCATCACCGTGGA
ATCCGATTTCGACTTCGAGTACGACGAGACGATGCAGAAGGCCCGGGCGCTGCGTGAGGCCGCTTCCGTTGACAGGGGGA
GCGTCGGCGAGTACAATCGTGGGCAAAACGAATAA

Upstream 100 bases:

>100_bases
GCGTGGAATTCGAACCGGGGAGCGTGTCGCGCGACGTGAACGACGCCTATGCCCGCATGGTGGCGCGGACGCGGGCCCGG
GCGCAGACGAAGGAGTTCCG

Downstream 100 bases:

>100_bases
CTATCTTCAGGGCAGGGTGCGATTCCCTACCGGTGGTACAGCCCACGAGCCGCAAGGCATGATTTGGTGAGATTCCAAAG
CCGACAGTACAGTCTGGATG

Product: para-aminobenzoate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSAQVFKLRTFRPLADIVERVRGEERFAFLDSSMPGAQGRYSILGLFPYLVIEHGRGGCLVDGVAVEGDFFDVVKKRLGP
CDGARDPRLPLTGGAIGYLGYDFGRESCGVPTRHDPVAATPEASMVFYDLLLIEDVRSRALFCCCQGRTMTAAHALTWAQ
DLVDSCPPAPHPARRRSLAPCSSDFTRAGYGDALARLVDHLRAGDAYVVNMAQRLRLETSESPYAIYRYLRTHNPAPFSA
YLRAPGLDVCCSSMERFMEIRSGHVVTRPIKGTRPRGGTPDEDRANREELARSEKDHSELLMVVDLERNDLSIVCEPGSV
GTDPDFAIETYPSVFHLVATVEGTLRKDRCAVDAVRAAFPTGSITGAPKVRAMQIIDELERAPRGLYTGSIGYFSDTGDC
DFNVVIRTIVREGGETSLGVGGGITVESDFDFEYDETMQKARALREAASVDRGSVGEYNRGQNE

Sequences:

>Translated_464_residues
MSAQVFKLRTFRPLADIVERVRGEERFAFLDSSMPGAQGRYSILGLFPYLVIEHGRGGCLVDGVAVEGDFFDVVKKRLGP
CDGARDPRLPLTGGAIGYLGYDFGRESCGVPTRHDPVAATPEASMVFYDLLLIEDVRSRALFCCCQGRTMTAAHALTWAQ
DLVDSCPPAPHPARRRSLAPCSSDFTRAGYGDALARLVDHLRAGDAYVVNMAQRLRLETSESPYAIYRYLRTHNPAPFSA
YLRAPGLDVCCSSMERFMEIRSGHVVTRPIKGTRPRGGTPDEDRANREELARSEKDHSELLMVVDLERNDLSIVCEPGSV
GTDPDFAIETYPSVFHLVATVEGTLRKDRCAVDAVRAAFPTGSITGAPKVRAMQIIDELERAPRGLYTGSIGYFSDTGDC
DFNVVIRTIVREGGETSLGVGGGITVESDFDFEYDETMQKARALREAASVDRGSVGEYNRGQNE
>Mature_463_residues
SAQVFKLRTFRPLADIVERVRGEERFAFLDSSMPGAQGRYSILGLFPYLVIEHGRGGCLVDGVAVEGDFFDVVKKRLGPC
DGARDPRLPLTGGAIGYLGYDFGRESCGVPTRHDPVAATPEASMVFYDLLLIEDVRSRALFCCCQGRTMTAAHALTWAQD
LVDSCPPAPHPARRRSLAPCSSDFTRAGYGDALARLVDHLRAGDAYVVNMAQRLRLETSESPYAIYRYLRTHNPAPFSAY
LRAPGLDVCCSSMERFMEIRSGHVVTRPIKGTRPRGGTPDEDRANREELARSEKDHSELLMVVDLERNDLSIVCEPGSVG
TDPDFAIETYPSVFHLVATVEGTLRKDRCAVDAVRAAFPTGSITGAPKVRAMQIIDELERAPRGLYTGSIGYFSDTGDCD
FNVVIRTIVREGGETSLGVGGGITVESDFDFEYDETMQKARALREAASVDRGSVGEYNRGQNE

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=360, Percent_Identity=39.1666666666667, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1787518, Length=299, Percent_Identity=37.123745819398, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=33.9407744874715, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6324361, Length=395, Percent_Identity=28.8607594936709, Blast_Score=142, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50887; Mature: 50756

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQVFKLRTFRPLADIVERVRGEERFAFLDSSMPGAQGRYSILGLFPYLVIEHGRGGCL
CCCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHEECCCCCEE
VDGVAVEGDFFDVVKKRLGPCDGARDPRLPLTGGAIGYLGYDFGRESCGVPTRHDPVAAT
EECEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
PEASMVFYDLLLIEDVRSRALFCCCQGRTMTAAHALTWAQDLVDSCPPAPHPARRRSLAP
CCHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
CSSDFTRAGYGDALARLVDHLRAGDAYVVNMAQRLRLETSESPYAIYRYLRTHNPAPFSA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHH
YLRAPGLDVCCSSMERFMEIRSGHVVTRPIKGTRPRGGTPDEDRANREELARSEKDHSEL
HHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHCCHHHHHHCCCCCCCE
LMVVDLERNDLSIVCEPGSVGTDPDFAIETYPSVFHLVATVEGTLRKDRCAVDAVRAAFP
EEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGSITGAPKVRAMQIIDELERAPRGLYTGSIGYFSDTGDCDFNVVIRTIVREGGETSLGV
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
GGGITVESDFDFEYDETMQKARALREAASVDRGSVGEYNRGQNE
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAQVFKLRTFRPLADIVERVRGEERFAFLDSSMPGAQGRYSILGLFPYLVIEHGRGGCL
CCCEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHEECCCCCEE
VDGVAVEGDFFDVVKKRLGPCDGARDPRLPLTGGAIGYLGYDFGRESCGVPTRHDPVAAT
EECEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCC
PEASMVFYDLLLIEDVRSRALFCCCQGRTMTAAHALTWAQDLVDSCPPAPHPARRRSLAP
CCHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
CSSDFTRAGYGDALARLVDHLRAGDAYVVNMAQRLRLETSESPYAIYRYLRTHNPAPFSA
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHH
YLRAPGLDVCCSSMERFMEIRSGHVVTRPIKGTRPRGGTPDEDRANREELARSEKDHSEL
HHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHCCHHHHHHCCCCCCCE
LMVVDLERNDLSIVCEPGSVGTDPDFAIETYPSVFHLVATVEGTLRKDRCAVDAVRAAFP
EEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TGSITGAPKVRAMQIIDELERAPRGLYTGSIGYFSDTGDCDFNVVIRTIVREGGETSLGV
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
GGGITVESDFDFEYDETMQKARALREAASVDRGSVGEYNRGQNE
CCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]