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The map label for this gene is ubiB [C]

Identifier: 213691152

GI number: 213691152

Start: 276870

End: 278690

Strand: Direct

Name: ubiB [C]

Synonym: Blon_0231

Alternate gene names: 213691152

Gene position: 276870-278690 (Clockwise)

Preceding gene: 213691151

Following gene: 213691153

Centisome position: 9.77

GC content: 59.69

Gene sequence:

>1821_bases
GTGACCAAGCCCACACGCACTACGCCGGAATCAGAGTCGACCCCGCTTTCCAGCAGGGTCGACCCTATTCTGACGCCTGC
GAAAGCCGAACGTGAGGCGGCGGCGAACCGGTCCGTCGACACGTCGGACACGCTCAAGCAGACCGTTACCAAGGCGACTC
CGAGCGTATCCGACGAAACGCTGGCACTGTTCGGACGCAGGAACGATTTCGCCACGCGCTACCATCTGACGCACCGTGGC
AAGATCAAACGACTGGGGCAGATCACCAGAATCGTCAAGCAATTCGACGTGCTGCACGGCCTGACTCCGGTCAAGATGCG
CCTCATGTTCGAGGCGCTCGGTCCCACGTTCGTCAAAGTGGGCCAGATTCTGTCGATGCGCTCCGAGATTCTGCCGCAAA
GCTTCTGCGACGAACTCGCCAAACTGCGCGCCGACGCCGACCCAATGCCGTATTCCACGGTGTTGGATGTGCTTGCCGCC
GAATACGGGCGTCCCGCCGACGAGGTGTTCGCGCATATCGACCCCAAGCCGTTGGGCTCTGCTTCACTGGCGCAAGTGCA
TCGCGCCACGCTGAAAACCGGCGAAGATGTGGCCATTAAAGTGCAGCGCCCGGGTGTACGCGAAATCATGGCCCAGGACG
TCTCCATCATGCGCTCCATAGCCAAGGCCGCCACTAAGGTGATTCGCACCTCACAGATCGTGGACCTGAAGGGCGTGGTC
GAGGAGCTGTGGGACACCTTCGAATCGGAGACTGACTTTCTGATCGAGGCCCGCAATCTCGCCGAATTCAAGCGTTTCGC
CGCCCGATTCAAATACATGGACTGCCCGACGGTGTACGCCGAACTGTGCACCGAGCATGTGGTGGTCATGGAGTACATCG
ACGGCATCTCCGTCTCCCACCCAGGCCAGCTCATCGACGCCGGTTATGACTTGAAGGAGATCGGCACCAAGCTCGTCGAC
AATTACGCCACACAGATTCTCGACGACGGCTTCTTCCACGCCGACCCACATCCCGGCAATATCCTCATCCGGGGCGGCCA
GATCGTACTTATCGACCTCGGTATGACCGGTCGGCTCGACCAGCGCACCCGTGCAGTCCTCAAAGAAATGATTTTCGCCG
TCGCCAAACAGGATTCGCCCGCTCTGGCCGAGGGGCTGCTGCGATTTGCCGGCACCGAGGCCGATCCGGAGGACTATCCC
GCGCTATTGGCCGATCTGGACGTGATCGTCAAGGAATTCGGCACCGTGGATCTGGCCGAACTGGACATTGCCGCTTTCCT
GACCGCACTGACGCAGATGGCCGGCCGCCACAACATCGAGGTGCCCAGTACGGTGACCACCGTCGGCCGCGCGTTGGTTA
CGCTCGAAGGCTTACTGGACGAGTTCATTCCTGATGTGAATATGATCGAAATCATTTCCGACCATATCGCCACGTCGAAA
TCGCTGAAGAACGCCACCAAAGACGAGATCAAGTCGCTGGGCGTTGAGGGGCATCAGGCTTTGCATGCCACGCTCGGCAC
CATGACCGAACTCAAGACCGTGGCCCGTATGCTGACCCGTGGTCAGTTGCGCGTCAACATGGAACTGGTCGGCTCCGAAG
AGCCGTTCCAGCTGCTTTCGGATATGGCGAACCGCCTGACCATGGCGTTGATCGTGGTGGGACTGTTCATCGGCTCGTCG
ATTGTCTACTACGCCGGCATGAAGCCGATTATCTTCGGCATTCCGGTCATCGGCTTCATGGGCTACGTCGTGGCCTTCGC
CCTCGGCGTATGGATCGTCATCGACATCTACTTAAAGGGCCGCAAGACCAGGAAGCGATGA

Upstream 100 bases:

>100_bases
TGGATGACGCCAAGAAGGCCGCCGCCGAAGCCGGCGACAAAGCTGCTGCCGCAGCCGACACCAGTGCCGCCGACAAGCCC
GCTGACGAGGGCAAGGCCGA

Downstream 100 bases:

>100_bases
GGCGCCGGCGCAACGCCTTCCCGTATGGGTATGATGGAATGTCGATTCACCGGGGAGAACAGCAATGACGGCATACATGG
AGCATAAGGACCTGACGAAC

Product: ABC-1 domain protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MTKPTRTTPESESTPLSSRVDPILTPAKAEREAAANRSVDTSDTLKQTVTKATPSVSDETLALFGRRNDFATRYHLTHRG
KIKRLGQITRIVKQFDVLHGLTPVKMRLMFEALGPTFVKVGQILSMRSEILPQSFCDELAKLRADADPMPYSTVLDVLAA
EYGRPADEVFAHIDPKPLGSASLAQVHRATLKTGEDVAIKVQRPGVREIMAQDVSIMRSIAKAATKVIRTSQIVDLKGVV
EELWDTFESETDFLIEARNLAEFKRFAARFKYMDCPTVYAELCTEHVVVMEYIDGISVSHPGQLIDAGYDLKEIGTKLVD
NYATQILDDGFFHADPHPGNILIRGGQIVLIDLGMTGRLDQRTRAVLKEMIFAVAKQDSPALAEGLLRFAGTEADPEDYP
ALLADLDVIVKEFGTVDLAELDIAAFLTALTQMAGRHNIEVPSTVTTVGRALVTLEGLLDEFIPDVNMIEIISDHIATSK
SLKNATKDEIKSLGVEGHQALHATLGTMTELKTVARMLTRGQLRVNMELVGSEEPFQLLSDMANRLTMALIVVGLFIGSS
IVYYAGMKPIIFGIPVIGFMGYVVAFALGVWIVIDIYLKGRKTRKR

Sequences:

>Translated_606_residues
MTKPTRTTPESESTPLSSRVDPILTPAKAEREAAANRSVDTSDTLKQTVTKATPSVSDETLALFGRRNDFATRYHLTHRG
KIKRLGQITRIVKQFDVLHGLTPVKMRLMFEALGPTFVKVGQILSMRSEILPQSFCDELAKLRADADPMPYSTVLDVLAA
EYGRPADEVFAHIDPKPLGSASLAQVHRATLKTGEDVAIKVQRPGVREIMAQDVSIMRSIAKAATKVIRTSQIVDLKGVV
EELWDTFESETDFLIEARNLAEFKRFAARFKYMDCPTVYAELCTEHVVVMEYIDGISVSHPGQLIDAGYDLKEIGTKLVD
NYATQILDDGFFHADPHPGNILIRGGQIVLIDLGMTGRLDQRTRAVLKEMIFAVAKQDSPALAEGLLRFAGTEADPEDYP
ALLADLDVIVKEFGTVDLAELDIAAFLTALTQMAGRHNIEVPSTVTTVGRALVTLEGLLDEFIPDVNMIEIISDHIATSK
SLKNATKDEIKSLGVEGHQALHATLGTMTELKTVARMLTRGQLRVNMELVGSEEPFQLLSDMANRLTMALIVVGLFIGSS
IVYYAGMKPIIFGIPVIGFMGYVVAFALGVWIVIDIYLKGRKTRKR
>Mature_605_residues
TKPTRTTPESESTPLSSRVDPILTPAKAEREAAANRSVDTSDTLKQTVTKATPSVSDETLALFGRRNDFATRYHLTHRGK
IKRLGQITRIVKQFDVLHGLTPVKMRLMFEALGPTFVKVGQILSMRSEILPQSFCDELAKLRADADPMPYSTVLDVLAAE
YGRPADEVFAHIDPKPLGSASLAQVHRATLKTGEDVAIKVQRPGVREIMAQDVSIMRSIAKAATKVIRTSQIVDLKGVVE
ELWDTFESETDFLIEARNLAEFKRFAARFKYMDCPTVYAELCTEHVVVMEYIDGISVSHPGQLIDAGYDLKEIGTKLVDN
YATQILDDGFFHADPHPGNILIRGGQIVLIDLGMTGRLDQRTRAVLKEMIFAVAKQDSPALAEGLLRFAGTEADPEDYPA
LLADLDVIVKEFGTVDLAELDIAAFLTALTQMAGRHNIEVPSTVTTVGRALVTLEGLLDEFIPDVNMIEIISDHIATSKS
LKNATKDEIKSLGVEGHQALHATLGTMTELKTVARMLTRGQLRVNMELVGSEEPFQLLSDMANRLTMALIVVGLFIGSSI
VYYAGMKPIIFGIPVIGFMGYVVAFALGVWIVIDIYLKGRKTRKR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=255, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI41393593, Length=270, Percent_Identity=30.3703703703704, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI217035081, Length=203, Percent_Identity=34.9753694581281, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI27363457, Length=248, Percent_Identity=29.8387096774194, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI217416386, Length=243, Percent_Identity=28.8065843621399, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI34147522, Length=272, Percent_Identity=25.3676470588235, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI2367309, Length=394, Percent_Identity=29.1878172588832, Blast_Score=160, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17559152, Length=271, Percent_Identity=31.3653136531365, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32565180, Length=250, Percent_Identity=28.4, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555620, Length=462, Percent_Identity=22.5108225108225, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325148, Length=439, Percent_Identity=24.8291571753986, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321319, Length=275, Percent_Identity=25.0909090909091, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323282, Length=280, Percent_Identity=24.6428571428571, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI22024280, Length=273, Percent_Identity=31.1355311355311, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24662575, Length=273, Percent_Identity=29.3040293040293, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI18859849, Length=247, Percent_Identity=27.9352226720648, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 66714; Mature: 66583

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50011 PROTEIN_KINASE_DOM ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPTRTTPESESTPLSSRVDPILTPAKAEREAAANRSVDTSDTLKQTVTKATPSVSDET
CCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCH
LALFGRRNDFATRYHLTHRGKIKRLGQITRIVKQFDVLHGLTPVKMRLMFEALGPTFVKV
HHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHH
GQILSMRSEILPQSFCDELAKLRADADPMPYSTVLDVLAAEYGRPADEVFAHIDPKPLGS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCC
ASLAQVHRATLKTGEDVAIKVQRPGVREIMAQDVSIMRSIAKAATKVIRTSQIVDLKGVV
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EELWDTFESETDFLIEARNLAEFKRFAARFKYMDCPTVYAELCTEHVVVMEYIDGISVSH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PGQLIDAGYDLKEIGTKLVDNYATQILDDGFFHADPHPGNILIRGGQIVLIDLGMTGRLD
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEECCCCCCCC
QRTRAVLKEMIFAVAKQDSPALAEGLLRFAGTEADPEDYPALLADLDVIVKEFGTVDLAE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LDIAAFLTALTQMAGRHNIEVPSTVTTVGRALVTLEGLLDEFIPDVNMIEIISDHIATSK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SLKNATKDEIKSLGVEGHQALHATLGTMTELKTVARMLTRGQLRVNMELVGSEEPFQLLS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
DMANRLTMALIVVGLFIGSSIVYYAGMKPIIFGIPVIGFMGYVVAFALGVWIVIDIYLKG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RKTRKR
CCCCCC
>Mature Secondary Structure 
TKPTRTTPESESTPLSSRVDPILTPAKAEREAAANRSVDTSDTLKQTVTKATPSVSDET
CCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCH
LALFGRRNDFATRYHLTHRGKIKRLGQITRIVKQFDVLHGLTPVKMRLMFEALGPTFVKV
HHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHH
GQILSMRSEILPQSFCDELAKLRADADPMPYSTVLDVLAAEYGRPADEVFAHIDPKPLGS
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCC
ASLAQVHRATLKTGEDVAIKVQRPGVREIMAQDVSIMRSIAKAATKVIRTSQIVDLKGVV
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EELWDTFESETDFLIEARNLAEFKRFAARFKYMDCPTVYAELCTEHVVVMEYIDGISVSH
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PGQLIDAGYDLKEIGTKLVDNYATQILDDGFFHADPHPGNILIRGGQIVLIDLGMTGRLD
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEECCCCCCCC
QRTRAVLKEMIFAVAKQDSPALAEGLLRFAGTEADPEDYPALLADLDVIVKEFGTVDLAE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
LDIAAFLTALTQMAGRHNIEVPSTVTTVGRALVTLEGLLDEFIPDVNMIEIISDHIATSK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SLKNATKDEIKSLGVEGHQALHATLGTMTELKTVARMLTRGQLRVNMELVGSEEPFQLLS
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
DMANRLTMALIVVGLFIGSSIVYYAGMKPIIFGIPVIGFMGYVVAFALGVWIVIDIYLKG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RKTRKR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA