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The map label for this gene is ilvC2 [H]

Identifier: 213691052

GI number: 213691052

Start: 155566

End: 156618

Strand: Direct

Name: ilvC2 [H]

Synonym: Blon_0131

Alternate gene names: 213691052

Gene position: 155566-156618 (Clockwise)

Preceding gene: 213691051

Following gene: 213691056

Centisome position: 5.49

GC content: 62.68

Gene sequence:

>1053_bases
ATGGCAGCAACTATCTGGTACGAGAAGGACGCCGATCTGTCCGTGTTCGATGGCAAGAAGGTCGCCATCTTGGGCTACGG
CTCTCAGGGTCACGCTCACGCACTGAACCTGCGTGACTCCGGTGTCGACGTGGTCGTCGGCCTGCGTCCGACCTCCAAGT
CTGTCGAGTTCGCCAAGGAGCAGGGCCTCGAGGTCAAGCCGGTTGGCGAGGCCGTCGCCGAGGCTGACGTTGTGATGATC
CTTCTGCCTGACCAGTACCAGGCCAAGGTCTACAAGGAAGAAGTTGAGCCGAACCTGAAGCCGGGCGCTGCCCTGGCGTT
CGCCCACGGCTTCAACATCCACTACGGCTACATCAAGCCGTCCGAGGATCACCCGGTGTTCATGGTTGCCCCGAAGGGCC
CGGGCCACATCGTTCGTCGTGAGTACGCCGCTGGCCGTGGCGTCCCGGTCGTCGTTGCCGTCGAGCAGGACCCGGACGGC
AAGACCTGGCCGTTGTGCCTGGCTTACGCCAAGGCTCTGGGCGCTCTGCGTGCAGGCGCCATCAAGACCACCTTCACCGA
GGAGACCGAGACCGATCTGTTCGGTGAGCAGGACGTCCTCATGGGTGGCATCAACCACCTGTGCGATCTCGGCTTCGACG
TGCTGACCGAGGCTGGCTACCAGCCGGAGATCGCCTACTTCGAGGTGTTCCACGAGCTGAAGATGCTCGTCGACCTGGCT
AACGAGGGTGGCCTGAACAAGGCTCGCTGGTCCTGCTCCGACACCGCTCAGTACGGCGACTACACCTCCACCGTCATCAC
CGACGAGACCAAGAAGCGCATGCAGTACCAGCTCAAGCGCATTCAGGACGGCTCCTTCGCCAAGGAGTTCATGGACGACC
AGGCCGCTGGCGCCCCGAAGTTCAAGAAGCTGCAGGAAGAGTACTCTCACCCGCACCTCGAGACCGTCGGCCCGAAGCTG
CGCGCCATGTTCTCCTGGAACAACGCCGAGGCCAAGGACAAGGACGAGGCCGAGTCCTTCAACGGCAAGATCGCCCGTAC
CCAGGTTCAGTGA

Upstream 100 bases:

>100_bases
GGAAAGCCAAAACTAAAAACAGTTTCTGCAGAACCAGCAGAGCACAATAACAATTAAAGATTTCACCCCCATAAACAAAT
AAATAAAAGGAGCGCCAAAA

Downstream 100 bases:

>100_bases
CCTATGACCTCCTTCTGATGAGGGAGGTGGCATCGCGTAGCGATGGCGGAGGGAGAGATCGTTAGGATTAAATCCCTTTG
TACAAGCAAGAAACCGCCGT

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase 2; Alpha-keto-beta-hydroxylacil reductoisomerase 2 [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MAATIWYEKDADLSVFDGKKVAILGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVEFAKEQGLEVKPVGEAVAEADVVMI
LLPDQYQAKVYKEEVEPNLKPGAALAFAHGFNIHYGYIKPSEDHPVFMVAPKGPGHIVRREYAAGRGVPVVVAVEQDPDG
KTWPLCLAYAKALGALRAGAIKTTFTEETETDLFGEQDVLMGGINHLCDLGFDVLTEAGYQPEIAYFEVFHELKMLVDLA
NEGGLNKARWSCSDTAQYGDYTSTVITDETKKRMQYQLKRIQDGSFAKEFMDDQAAGAPKFKKLQEEYSHPHLETVGPKL
RAMFSWNNAEAKDKDEAESFNGKIARTQVQ

Sequences:

>Translated_350_residues
MAATIWYEKDADLSVFDGKKVAILGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVEFAKEQGLEVKPVGEAVAEADVVMI
LLPDQYQAKVYKEEVEPNLKPGAALAFAHGFNIHYGYIKPSEDHPVFMVAPKGPGHIVRREYAAGRGVPVVVAVEQDPDG
KTWPLCLAYAKALGALRAGAIKTTFTEETETDLFGEQDVLMGGINHLCDLGFDVLTEAGYQPEIAYFEVFHELKMLVDLA
NEGGLNKARWSCSDTAQYGDYTSTVITDETKKRMQYQLKRIQDGSFAKEFMDDQAAGAPKFKKLQEEYSHPHLETVGPKL
RAMFSWNNAEAKDKDEAESFNGKIARTQVQ
>Mature_349_residues
AATIWYEKDADLSVFDGKKVAILGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVEFAKEQGLEVKPVGEAVAEADVVMIL
LPDQYQAKVYKEEVEPNLKPGAALAFAHGFNIHYGYIKPSEDHPVFMVAPKGPGHIVRREYAAGRGVPVVVAVEQDPDGK
TWPLCLAYAKALGALRAGAIKTTFTEETETDLFGEQDVLMGGINHLCDLGFDVLTEAGYQPEIAYFEVFHELKMLVDLAN
EGGLNKARWSCSDTAQYGDYTSTVITDETKKRMQYQLKRIQDGSFAKEFMDDQAAGAPKFKKLQEEYSHPHLETVGPKLR
AMFSWNNAEAKDKDEAESFNGKIARTQVQ

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=313, Percent_Identity=35.1437699680511, Blast_Score=151, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6323387, Length=261, Percent_Identity=34.8659003831418, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 38580; Mature: 38449

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIWYEKDADLSVFDGKKVAILGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVEFAKE
CCEEEEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHH
QGLEVKPVGEAVAEADVVMILLPDQYQAKVYKEEVEPNLKPGAALAFAHGFNIHYGYIKP
CCCEECCHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECC
SEDHPVFMVAPKGPGHIVRREYAAGRGVPVVVAVEQDPDGKTWPLCLAYAKALGALRAGA
CCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
IKTTFTEETETDLFGEQDVLMGGINHLCDLGFDVLTEAGYQPEIAYFEVFHELKMLVDLA
EEEEECCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
NEGGLNKARWSCSDTAQYGDYTSTVITDETKKRMQYQLKRIQDGSFAKEFMDDQAAGAPK
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
FKKLQEEYSHPHLETVGPKLRAMFSWNNAEAKDKDEAESFNGKIARTQVQ
HHHHHHHHCCCCHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCEEEEECC
>Mature Secondary Structure 
AATIWYEKDADLSVFDGKKVAILGYGSQGHAHALNLRDSGVDVVVGLRPTSKSVEFAKE
CEEEEECCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHH
QGLEVKPVGEAVAEADVVMILLPDQYQAKVYKEEVEPNLKPGAALAFAHGFNIHYGYIKP
CCCEECCHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEEECC
SEDHPVFMVAPKGPGHIVRREYAAGRGVPVVVAVEQDPDGKTWPLCLAYAKALGALRAGA
CCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
IKTTFTEETETDLFGEQDVLMGGINHLCDLGFDVLTEAGYQPEIAYFEVFHELKMLVDLA
EEEEECCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
NEGGLNKARWSCSDTAQYGDYTSTVITDETKKRMQYQLKRIQDGSFAKEFMDDQAAGAPK
CCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCH
FKKLQEEYSHPHLETVGPKLRAMFSWNNAEAKDKDEAESFNGKIARTQVQ
HHHHHHHHCCCCHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]