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The map label for this gene is fprA [H]

Identifier: 213691037

GI number: 213691037

Start: 137020

End: 138471

Strand: Direct

Name: fprA [H]

Synonym: Blon_0116

Alternate gene names: 213691037

Gene position: 137020-138471 (Clockwise)

Preceding gene: 213691036

Following gene: 213691038

Centisome position: 4.84

GC content: 64.88

Gene sequence:

>1452_bases
GTGACTGAATCCGTGAATACTGAACTCCGCATTGCTGTAATCGGCGCCGGGCCGGCCGGCGTCTATTCCTCCGACATCTT
CCTGCGCCAGCTCAAGAAGTTGGGTGAGGGACTCGGCCTTGGCGCCGAAGCGCGCATCGACCTGTTCGAAAAACTGCCGG
TACCTTTCGGGCTGGTGCGTTACGGCGTGGCCCCGGACCACCCGTCCATCAAGTTCATCGCCTCCGCGCTTGAGAAGACG
CTCGACAACCCGAACATCCACCTGTACTGCGATGTGGAATTCGGCAAGGACGTGACCCTCGACGAACTGCTGGCCCGCTA
TGACGCCGTGCTGTTCGCCACCGGCGCGGTCAAGGACAAGCCGCTGAACCTGCCCGGCGCCGACCTTGAAGGCGTGTACG
GCGCCGCCAAGTTCGTCGAATGGTACGACGGTTACCCCACCGGTGCCCGCGAATGGCCGCTTACGGCCGAGAACGTCGCC
GTGATCGGCGGCGGCAACGTGGCCATGGATGTGGCCCGCGAGCTCATGCGTAACGCCGACGACCTCAAGGCCAAGACCGA
CATTCCGGATAACGTGTACGAGGGCATCGGCCGCAACAAGGCCAAGGTGCTGCACCTGTTCATCCGTCGTGGCGTGGCCC
AGGCCAAGTTCAGCGTGCAGGAACTGCGCGAGATGGAGAAGCTGCCCGGCGTGCAGCTCATCATCAACGAGGACGACTTC
GAGCTGGACGACGACACCATCGAGGTGGCCGGCAAGGACAAGCTCACCCGTCAGATGGTCGAGGAACTGTTCGCCATCCG
CGAGATGGCCGAAGACATGCAAGACGATGGCGACGTCGACTTCGAAGGCAATCCGGCCGACCGCAGGTATTACGTGCACT
TCAACTCCGCCCCCACCGAGATTCTCGGCGAGGACGGCAAGGTCAAGGCCATCCGCGTGGAACGTACCGAGACCGGCGCC
GATGGCAGGATGCGCCGCACCGGCGAGTTCACGGACTACCCGGTCGAGGCCGTCTACCATGCCATCGGCTACCGGCCCGC
CGAAGCCCCCGGCATCGCCTACGACGAGCATGGCGCCCACCTGGCCAACGCCAACGGCGACGGCCGCATCACCGCCGATG
CCGACGGCGGCGACGTGCGCGAACGGCTGTACGCCACCGGTTGGGCCAAGCGCGGCCCGGTGGGTCTGATCGGTTCCACC
AAATCCGATGCGCTGGCCATCGTGACCAACATGCTTGAAGATCTGGCAAGTGCCGCCGAGGGCGGCCGTGTGGCGCAAGA
CCGTGACCCCGACTCCATCGACCGACTGCTGGCCGAGCGCGGCATTCGCCCGATCGACTTCGCCGGCTGGAAAAAGGTCG
ATGCCTTCGAGCGTGCCGAGGGCGCCAAGGAAGGCCGCGAACACAAGAAGGTCATCGATCCCGAGCAGATGCGCGAGCTC
GCCCACGCCTGA

Upstream 100 bases:

>100_bases
CGAACACGACCAAGAGGCGAACCGGCCGGGCGCGAGATGCGCCCGCACCCCCACGAATGACCCCTATCGCAACGGAAGGC
TTTGCGCTAGGGTAGAGCGT

Downstream 100 bases:

>100_bases
CGGTTCGCCCGCGCCGTCCGGCACCCGTCCGTACCCGCGCCCCGTGTGGGCGCGGCCGGGCGGACCGGGCGAATATTCGA
CATTGCGCTTGGCGCATATC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MTESVNTELRIAVIGAGPAGVYSSDIFLRQLKKLGEGLGLGAEARIDLFEKLPVPFGLVRYGVAPDHPSIKFIASALEKT
LDNPNIHLYCDVEFGKDVTLDELLARYDAVLFATGAVKDKPLNLPGADLEGVYGAAKFVEWYDGYPTGAREWPLTAENVA
VIGGGNVAMDVARELMRNADDLKAKTDIPDNVYEGIGRNKAKVLHLFIRRGVAQAKFSVQELREMEKLPGVQLIINEDDF
ELDDDTIEVAGKDKLTRQMVEELFAIREMAEDMQDDGDVDFEGNPADRRYYVHFNSAPTEILGEDGKVKAIRVERTETGA
DGRMRRTGEFTDYPVEAVYHAIGYRPAEAPGIAYDEHGAHLANANGDGRITADADGGDVRERLYATGWAKRGPVGLIGST
KSDALAIVTNMLEDLASAAEGGRVAQDRDPDSIDRLLAERGIRPIDFAGWKKVDAFERAEGAKEGREHKKVIDPEQMREL
AHA

Sequences:

>Translated_483_residues
MTESVNTELRIAVIGAGPAGVYSSDIFLRQLKKLGEGLGLGAEARIDLFEKLPVPFGLVRYGVAPDHPSIKFIASALEKT
LDNPNIHLYCDVEFGKDVTLDELLARYDAVLFATGAVKDKPLNLPGADLEGVYGAAKFVEWYDGYPTGAREWPLTAENVA
VIGGGNVAMDVARELMRNADDLKAKTDIPDNVYEGIGRNKAKVLHLFIRRGVAQAKFSVQELREMEKLPGVQLIINEDDF
ELDDDTIEVAGKDKLTRQMVEELFAIREMAEDMQDDGDVDFEGNPADRRYYVHFNSAPTEILGEDGKVKAIRVERTETGA
DGRMRRTGEFTDYPVEAVYHAIGYRPAEAPGIAYDEHGAHLANANGDGRITADADGGDVRERLYATGWAKRGPVGLIGST
KSDALAIVTNMLEDLASAAEGGRVAQDRDPDSIDRLLAERGIRPIDFAGWKKVDAFERAEGAKEGREHKKVIDPEQMREL
AHA
>Mature_482_residues
TESVNTELRIAVIGAGPAGVYSSDIFLRQLKKLGEGLGLGAEARIDLFEKLPVPFGLVRYGVAPDHPSIKFIASALEKTL
DNPNIHLYCDVEFGKDVTLDELLARYDAVLFATGAVKDKPLNLPGADLEGVYGAAKFVEWYDGYPTGAREWPLTAENVAV
IGGGNVAMDVARELMRNADDLKAKTDIPDNVYEGIGRNKAKVLHLFIRRGVAQAKFSVQELREMEKLPGVQLIINEDDFE
LDDDTIEVAGKDKLTRQMVEELFAIREMAEDMQDDGDVDFEGNPADRRYYVHFNSAPTEILGEDGKVKAIRVERTETGAD
GRMRRTGEFTDYPVEAVYHAIGYRPAEAPGIAYDEHGAHLANANGDGRITADADGGDVRERLYATGWAKRGPVGLIGSTK
SDALAIVTNMLEDLASAAEGGRVAQDRDPDSIDRLLAERGIRPIDFAGWKKVDAFERAEGAKEGREHKKVIDPEQMRELA
HA

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118983, Length=492, Percent_Identity=34.349593495935, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI111118981, Length=487, Percent_Identity=34.4969199178645, Blast_Score=244, Evalue=2e-64,
Organism=Escherichia coli, GI1788811, Length=187, Percent_Identity=32.0855614973262, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082180, Length=175, Percent_Identity=30.8571428571429, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789606, Length=184, Percent_Identity=29.8913043478261, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543860, Length=474, Percent_Identity=28.9029535864979, Blast_Score=207, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320584, Length=499, Percent_Identity=27.0541082164329, Blast_Score=172, Evalue=8e-44,
Organism=Drosophila melanogaster, GI17137178, Length=484, Percent_Identity=32.2314049586777, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI28574881, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665539, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665547, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24665543, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 52972; Mature: 52841

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESVNTELRIAVIGAGPAGVYSSDIFLRQLKKLGEGLGLGAEARIDLFEKLPVPFGLVR
CCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHH
YGVAPDHPSIKFIASALEKTLDNPNIHLYCDVEFGKDVTLDELLARYDAVLFATGAVKDK
HCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCCCCC
PLNLPGADLEGVYGAAKFVEWYDGYPTGAREWPLTAENVAVIGGGNVAMDVARELMRNAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCHH
DLKAKTDIPDNVYEGIGRNKAKVLHLFIRRGVAQAKFSVQELREMEKLPGVQLIINEDDF
HCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
ELDDDTIEVAGKDKLTRQMVEELFAIREMAEDMQDDGDVDFEGNPADRRYYVHFNSAPTE
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHH
ILGEDGKVKAIRVERTETGADGRMRRTGEFTDYPVEAVYHAIGYRPAEAPGIAYDEHGAH
HHCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCCCE
LANANGDGRITADADGGDVRERLYATGWAKRGPVGLIGSTKSDALAIVTNMLEDLASAAE
EECCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHC
GGRVAQDRDPDSIDRLLAERGIRPIDFAGWKKVDAFERAEGAKEGREHKKVIDPEQMREL
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AHA
HCC
>Mature Secondary Structure 
TESVNTELRIAVIGAGPAGVYSSDIFLRQLKKLGEGLGLGAEARIDLFEKLPVPFGLVR
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHH
YGVAPDHPSIKFIASALEKTLDNPNIHLYCDVEFGKDVTLDELLARYDAVLFATGAVKDK
HCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCCCCC
PLNLPGADLEGVYGAAKFVEWYDGYPTGAREWPLTAENVAVIGGGNVAMDVARELMRNAD
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCHH
DLKAKTDIPDNVYEGIGRNKAKVLHLFIRRGVAQAKFSVQELREMEKLPGVQLIINEDDF
HCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
ELDDDTIEVAGKDKLTRQMVEELFAIREMAEDMQDDGDVDFEGNPADRRYYVHFNSAPTE
CCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHH
ILGEDGKVKAIRVERTETGADGRMRRTGEFTDYPVEAVYHAIGYRPAEAPGIAYDEHGAH
HHCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCCEECCCCCE
LANANGDGRITADADGGDVRERLYATGWAKRGPVGLIGSTKSDALAIVTNMLEDLASAAE
EECCCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHC
GGRVAQDRDPDSIDRLLAERGIRPIDFAGWKKVDAFERAEGAKEGREHKKVIDPEQMREL
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AHA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]