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The map label for this gene is degP [C]

Identifier: 213691023

GI number: 213691023

Start: 119743

End: 121794

Strand: Direct

Name: degP [C]

Synonym: Blon_0102

Alternate gene names: 213691023

Gene position: 119743-121794 (Clockwise)

Preceding gene: 213691019

Following gene: 213691024

Centisome position: 4.23

GC content: 66.13

Gene sequence:

>2052_bases
ATGGCTGACGAATTCAACCCGCAGGGCGTCGACCAGACCCCGCGGAATAACGAAACCCCCAATGATACTGCCGATGCCGG
CAACGCCGAGCCGAAGAACCCGTTTGTAGGCGGCGACTCGGTCGATGCCGGCAACGCCAGCGATTCCAACGAGCAGCAAG
CCCCGGTTTCCCCGGCCGCCCCCGCTGCCGATCAGCAGCCTACGCAAGCCGCTACCGACACCGCCGCCACTGAGCCCATC
CCGGACTACGCCTCCGCCAAGGGCGAGAGCACGGTGGTCTCCTCCTCGCCGGCTTCTCCGGCAGCGCCGGCCGCAGACCA
GACCTCGGCCACAACTCCGCTGTACCGCCCGGCCCCGGAATACGGCGCTTATGGTCCGACCCCGACTCAGGCACAGGGCC
AGCAGGGCGGCCAGGCCGGCAACAATGCCCAGCCCACGCAGCAATTCCCGTTCGGTCAGCCTGCACAGCAAACCCCACAG
GGCCAGCAAGGCAACCGCAATCCCTACTACACCAATAACCCGCAGCCGCAGGGCAACGGCAATCCGTTCAATCCGCCCAC
GCAGCCGCAGCAGAACATCGGCAACCCATTCGCCAGCCAGTCCGGCCAGAATGGCCAGAATGGCCAGCAGCCCCAGCAGG
GCGGTCTGTTCGGTTTCGGCACTCCCGGTACCGGTACGCCGAACGGTCAAGGTCCGACCCAGCCGGGACAGCCCGGTCAG
CCCGGCCCCGCCAAGCAGGGCATGTCCAAGACGGCGAGCAACATCCTCATCGCCGTGGTCGCCGCCGTCGTGTCCGCGGC
CCTGTGCCTGGGCCTCGGCTACGGCGCCCTCACCAGCGGCCTGATCACCCTGCCGACCAGCAATTCGCTGTCCAACGTCA
GCTCGAATAAGTCCGGCTCCGGGTCCGCCACCGCCAAGAGCGGCGAAGCCCCCGACTGGCAGACCGTCGCCAGCGATGTC
TCCGGCTCCGTGGTCTCCATCCAGACCGCGTTGAGCAACGGCACCGCCAAGGGCTCCGGCGCCATCATCGACACCGAAGG
CCACATCATCACCAACAACCACGTGATCTCCGGGGCCCAGCAGATCCAAGTGACGCTTGCCAACGGCAACATGTATTCCG
CCACGCTTGTCGGCACCGACACCACCACCGATCTTGCGGTCATCAAGCTCGACAACCCGCCGAGCGACCTCAAGGCCGTG
AAATTCGCCGATTCCGACAAGCTCGCCGTCGGCGAGAACGTGATGGCCATCGGCAACCCGCTCGGCTACGACGACACCGC
CACCACCGGCATCGTCTCCGCCCTGAACCGCCCGGTGACCGTGACCGACGATAACAACAACGAGATCGTCACCAACGCCG
TCCAGATCGACGCGGCCATCAACCCCGGCAACTCCGGCGGTCCGACCTTCAACGCGGCCGGCCAGGTGATCGGCATCAAC
TCGTCCATCGCCTCGACTGCCACCTCATCCGACTCCGCCGGTTCGATCGGCATCGGCTTCGCCATCCCGTCCAACCTCGT
CAAGCGTGTGGCCGACGAAATCATCAAGGACGGCAAGGTCAAGCACGTTGCCCTCGGCGTGGTCATCAAGTCCGACACGG
TTGAAGCCGACGGCGTGACCCGCGGCGGCGCGACCATCACCAAGTCCAGCGCCACCGGCAGCGCGGTCGTCTCCGGCGGC
CCGGCCGACAAGGCCGGCCTCAAGGAGGGCGACACCATCGTGGCCTTCAACGGCAACGCGGTGAACAACAACTACTCGCT
GCTTGGTTACGTTCGTGCCGCGGCTTTGGGAGACAAGGTGACGCTGACCATCGTGCGCGATGGCAAGACCATGGATGTGG
ACGTGACGCTCGATCAGGAGGAGTCGTCGGTGAACGGTTCGTCCGGCGCCAACGGCAACAGCAACGGCCAGAACAACAAG
CGCAACCGGAACGGCGACGGCGCCAACGGCAACAACGGCGGCGACGATGGCAACGGCCAGAACGGCAACGGCCGCAACGA
TGGAGGCACCGGTGACGGCGGCGGCTTCACCGATCCGTTCGGCCTGTGGTAA

Upstream 100 bases:

>100_bases
ACTGCCTTTACTAATGAGGTAGCACACGAGAAGCGGCAATGAGCAAGCGCCCGAATAGCCGCCGAACAGACGTGATAAGA
ATTTAGGAAAAGGAGTAGCA

Downstream 100 bases:

>100_bases
AGGCCTGCGGTAAAGCGGATGGCGCGTCGCGCGGCGGTGGACGATAGTCGCTGAACGCGCGTCGGGCCGGTCAGGGGCCG
TGGCGGTGAGCGAGTCTGCC

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 682

Protein sequence:

>683_residues
MADEFNPQGVDQTPRNNETPNDTADAGNAEPKNPFVGGDSVDAGNASDSNEQQAPVSPAAPAADQQPTQAATDTAATEPI
PDYASAKGESTVVSSSPASPAAPAADQTSATTPLYRPAPEYGAYGPTPTQAQGQQGGQAGNNAQPTQQFPFGQPAQQTPQ
GQQGNRNPYYTNNPQPQGNGNPFNPPTQPQQNIGNPFASQSGQNGQNGQQPQQGGLFGFGTPGTGTPNGQGPTQPGQPGQ
PGPAKQGMSKTASNILIAVVAAVVSAALCLGLGYGALTSGLITLPTSNSLSNVSSNKSGSGSATAKSGEAPDWQTVASDV
SGSVVSIQTALSNGTAKGSGAIIDTEGHIITNNHVISGAQQIQVTLANGNMYSATLVGTDTTTDLAVIKLDNPPSDLKAV
KFADSDKLAVGENVMAIGNPLGYDDTATTGIVSALNRPVTVTDDNNNEIVTNAVQIDAAINPGNSGGPTFNAAGQVIGIN
SSIASTATSSDSAGSIGIGFAIPSNLVKRVADEIIKDGKVKHVALGVVIKSDTVEADGVTRGGATITKSSATGSAVVSGG
PADKAGLKEGDTIVAFNGNAVNNNYSLLGYVRAAALGDKVTLTIVRDGKTMDVDVTLDQEESSVNGSSGANGNSNGQNNK
RNRNGDGANGNNGGDDGNGQNGNGRNDGGTGDGGGFTDPFGLW

Sequences:

>Translated_683_residues
MADEFNPQGVDQTPRNNETPNDTADAGNAEPKNPFVGGDSVDAGNASDSNEQQAPVSPAAPAADQQPTQAATDTAATEPI
PDYASAKGESTVVSSSPASPAAPAADQTSATTPLYRPAPEYGAYGPTPTQAQGQQGGQAGNNAQPTQQFPFGQPAQQTPQ
GQQGNRNPYYTNNPQPQGNGNPFNPPTQPQQNIGNPFASQSGQNGQNGQQPQQGGLFGFGTPGTGTPNGQGPTQPGQPGQ
PGPAKQGMSKTASNILIAVVAAVVSAALCLGLGYGALTSGLITLPTSNSLSNVSSNKSGSGSATAKSGEAPDWQTVASDV
SGSVVSIQTALSNGTAKGSGAIIDTEGHIITNNHVISGAQQIQVTLANGNMYSATLVGTDTTTDLAVIKLDNPPSDLKAV
KFADSDKLAVGENVMAIGNPLGYDDTATTGIVSALNRPVTVTDDNNNEIVTNAVQIDAAINPGNSGGPTFNAAGQVIGIN
SSIASTATSSDSAGSIGIGFAIPSNLVKRVADEIIKDGKVKHVALGVVIKSDTVEADGVTRGGATITKSSATGSAVVSGG
PADKAGLKEGDTIVAFNGNAVNNNYSLLGYVRAAALGDKVTLTIVRDGKTMDVDVTLDQEESSVNGSSGANGNSNGQNNK
RNRNGDGANGNNGGDDGNGQNGNGRNDGGTGDGGGFTDPFGLW
>Mature_682_residues
ADEFNPQGVDQTPRNNETPNDTADAGNAEPKNPFVGGDSVDAGNASDSNEQQAPVSPAAPAADQQPTQAATDTAATEPIP
DYASAKGESTVVSSSPASPAAPAADQTSATTPLYRPAPEYGAYGPTPTQAQGQQGGQAGNNAQPTQQFPFGQPAQQTPQG
QQGNRNPYYTNNPQPQGNGNPFNPPTQPQQNIGNPFASQSGQNGQNGQQPQQGGLFGFGTPGTGTPNGQGPTQPGQPGQP
GPAKQGMSKTASNILIAVVAAVVSAALCLGLGYGALTSGLITLPTSNSLSNVSSNKSGSGSATAKSGEAPDWQTVASDVS
GSVVSIQTALSNGTAKGSGAIIDTEGHIITNNHVISGAQQIQVTLANGNMYSATLVGTDTTTDLAVIKLDNPPSDLKAVK
FADSDKLAVGENVMAIGNPLGYDDTATTGIVSALNRPVTVTDDNNNEIVTNAVQIDAAINPGNSGGPTFNAAGQVIGINS
SIASTATSSDSAGSIGIGFAIPSNLVKRVADEIIKDGKVKHVALGVVIKSDTVEADGVTRGGATITKSSATGSAVVSGGP
ADKAGLKEGDTIVAFNGNAVNNNYSLLGYVRAAALGDKVTLTIVRDGKTMDVDVTLDQEESSVNGSSGANGNSNGQNNKR
NRNGDGANGNNGGDDGNGQNGNGRNDGGTGDGGGFTDPFGLW

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=315, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=6e-29,
Organism=Homo sapiens, GI4506141, Length=256, Percent_Identity=35.15625, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI24308541, Length=285, Percent_Identity=35.4385964912281, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7019477, Length=299, Percent_Identity=29.7658862876254, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1786356, Length=303, Percent_Identity=41.5841584158416, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1789629, Length=282, Percent_Identity=42.1985815602837, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789630, Length=372, Percent_Identity=30.9139784946237, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24646839, Length=346, Percent_Identity=29.7687861271676, Blast_Score=107, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 68335; Mature: 68204

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: PS50106 PDZ ; PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEFNPQGVDQTPRNNETPNDTADAGNAEPKNPFVGGDSVDAGNASDSNEQQAPVSPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAADQQPTQAATDTAATEPIPDYASAKGESTVVSSSPASPAAPAADQTSATTPLYRPAPE
CCCCCCCCHHHCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
YGAYGPTPTQAQGQQGGQAGNNAQPTQQFPFGQPAQQTPQGQQGNRNPYYTNNPQPQGNG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
NPFNPPTQPQQNIGNPFASQSGQNGQNGQQPQQGGLFGFGTPGTGTPNGQGPTQPGQPGQ
CCCCCCCCCHHHCCCCHHHCCCCCCCCCCCCHHCCEEEECCCCCCCCCCCCCCCCCCCCC
PGPAKQGMSKTASNILIAVVAAVVSAALCLGLGYGALTSGLITLPTSNSLSNVSSNKSGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCHHHCCCCCCCC
GSATAKSGEAPDWQTVASDVSGSVVSIQTALSNGTAKGSGAIIDTEGHIITNNHVISGAQ
CCCCCCCCCCCCHHHHHHHCCCCEEEEEEHHCCCCCCCCCCEEECCCCEEECCEEECCCE
QIQVTLANGNMYSATLVGTDTTTDLAVIKLDNPPSDLKAVKFADSDKLAVGENVMAIGNP
EEEEEEECCCEEEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCEEECCCEEEECCC
LGYDDTATTGIVSALNRPVTVTDDNNNEIVTNAVQIDAAINPGNSGGPTFNAAGQVIGIN
CCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCEEECC
SSIASTATSSDSAGSIGIGFAIPSNLVKRVADEIIKDGKVKHVALGVVIKSDTVEADGVT
CHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCC
RGGATITKSSATGSAVVSGGPADKAGLKEGDTIVAFNGNAVNNNYSLLGYVRAAALGDKV
CCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEEEECCCEECCCCEEEEHHHHHHCCCEE
TLTIVRDGKTMDVDVTLDQEESSVNGSSGANGNSNGQNNKRNRNGDGANGNNGGDDGNGQ
EEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGNGRNDGGTGDGGGFTDPFGLW
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADEFNPQGVDQTPRNNETPNDTADAGNAEPKNPFVGGDSVDAGNASDSNEQQAPVSPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAADQQPTQAATDTAATEPIPDYASAKGESTVVSSSPASPAAPAADQTSATTPLYRPAPE
CCCCCCCCHHHCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
YGAYGPTPTQAQGQQGGQAGNNAQPTQQFPFGQPAQQTPQGQQGNRNPYYTNNPQPQGNG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
NPFNPPTQPQQNIGNPFASQSGQNGQNGQQPQQGGLFGFGTPGTGTPNGQGPTQPGQPGQ
CCCCCCCCCHHHCCCCHHHCCCCCCCCCCCCHHCCEEEECCCCCCCCCCCCCCCCCCCCC
PGPAKQGMSKTASNILIAVVAAVVSAALCLGLGYGALTSGLITLPTSNSLSNVSSNKSGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCHHHCCCCCCCC
GSATAKSGEAPDWQTVASDVSGSVVSIQTALSNGTAKGSGAIIDTEGHIITNNHVISGAQ
CCCCCCCCCCCCHHHHHHHCCCCEEEEEEHHCCCCCCCCCCEEECCCCEEECCEEECCCE
QIQVTLANGNMYSATLVGTDTTTDLAVIKLDNPPSDLKAVKFADSDKLAVGENVMAIGNP
EEEEEEECCCEEEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCEEECCCEEEECCC
LGYDDTATTGIVSALNRPVTVTDDNNNEIVTNAVQIDAAINPGNSGGPTFNAAGQVIGIN
CCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCEEECC
SSIASTATSSDSAGSIGIGFAIPSNLVKRVADEIIKDGKVKHVALGVVIKSDTVEADGVT
CHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCC
RGGATITKSSATGSAVVSGGPADKAGLKEGDTIVAFNGNAVNNNYSLLGYVRAAALGDKV
CCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEEEECCCEECCCCEEEEHHHHHHCCCEE
TLTIVRDGKTMDVDVTLDQEESSVNGSSGANGNSNGQNNKRNRNGDGANGNNGGDDGNGQ
EEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NGNGRNDGGTGDGGGFTDPFGLW
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]