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The map label for this gene is hbpA [H]

Identifier: 213690975

GI number: 213690975

Start: 59327

End: 61039

Strand: Direct

Name: hbpA [H]

Synonym: Blon_0053

Alternate gene names: 213690975

Gene position: 59327-61039 (Clockwise)

Preceding gene: 213690974

Following gene: 213690976

Centisome position: 2.09

GC content: 55.75

Gene sequence:

>1713_bases
ATGCGTAAGCATCTTGTAGCTGTGGTCGCGGCGGCGGCAGCATTGCTGCTGGTGGCTGGTTGTGGCGGCACGAGCGGCGG
CAGTAATGCGGAATCCACGGAAACCACCGTCGACGGCAGCCTGAACAAGGTCGTGGTCAAGGGCGATCCAAGTAAAAGCC
CCGCCAAGGCCAACGGCCGTAAGGACACATTCATCGCCACGATCAATTCTCCGAGCGGTGTGTTCTTGCCGGGGTTCAAT
GACAATGGCTGGGATGGCAACGCGCAGCAGCCGATTTTCGCGAGTCTGGTGGTGACCGATGATTCGGGACAGTATATTCC
CGACTTGGCCGAGAAATGGGATATCTCCAGTGATCAGCTCACGTACACCTTCCATCTGCGCGACAATCTGAAATTCTCGG
ATGGGTCGCCGCTGACCGCGGACGATGTGGCTTTCAGCCTGACGCTGTTCAATGATCCGGCTTACTCGGGCGGCAGTGAT
TTCTCCGACATCGGCATCAAAGGCGTTGATGCGTACAAGTCGGGCAAGGCTGATTCCATCTCCGGCATCCGGGTGATCGA
CGAGCGGACCATCACCATTGAGACCACGAAAGCGAATCCGCTGACATTGGGCATTCTTGGCGGCCAGGTGCTGTCGAAAG
CATATTACGGCAAGGACTACCAGCGAGGGCACCTTGATTATCTGAAGGATCTGTACGGCAAGCCTTTGGGCGCCGGCCCC
TACAAGCTGTCCAAATATGTGGATGGTCAGGAAGTGCGGTATGTTGCCAACAAGTACTACTATGGCGGCGAACCGAAGAT
CAGGAATCTGATTTTTAAGGTCACCTCCAAGGACACGGCGCTGTCGAACTTCCAGAACGGCGAAACCGATTTTGATGGTT
TCAGCCCGGACAAAGATAATCTTGACGCACTGAAGCAGCTTGGCTTTGCCAGTGTGCGCGAAAGCACGGTGCCGGACATG
AGTGAGATCTGGATCAATAACCTCAAGGCCCCGTTCAACGACAAGCGAGTCCGTCAGGCGTTGATCTATGGTCTCAACCG
TCAGCAGATCATCAACGTGGCGTATAAGGGATTCGGCCAGGTGGCGAACGTGTATGCCGCTCCTACGCAATGGTCGTACA
CCGATAAGGGAGTCAACAAGTACAAGTTCGATCCGGACAAGGCGGGCAAGCTGCTTGACGAGGCCGGTTGGAAGACCGGC
TCGGACGGGATTCGCGAAAAAGATGGCAGGAAGCTCACCGTACGGTACCTGACTTCCAAGGACACGGATGAGACGATCCC
GATTGCCACGGAGAACTACAAAGCCATCGGCATTGACTTCCAGCCTGAAGTGCTCGATGGCGACACCATCATCGAACGAT
GGACGCAGGGCGGCGATTGGGATTTGGTCGGCGGATTCCGCACCAACGGTTTGTCGGATCCGAACGACGCGATTTCCGAA
TTCGTCTCGCACGACAAGTCCATCAACCTCACGGGCTACCACAATGAGGAAGCCGACAAGCTCGCCAAGGAAGGGCTGTC
CACTCAGGATAAGACAAAACGCAAGGCCATCTATGCGGAGCTCTACAAGGTTCTGAACAATGATCCGCCCACCATTCCAT
TGAGCTATCGGCAGTCCATCACGGCATGGAACACCCGTGTCAAGGGTGTTGAGAACTATTCGACCGGCAATAGCGATGCG
GCGCTCGTCCTCGCGAAGCTTTCGATCGAATAG

Upstream 100 bases:

>100_bases
TGGATGTATCTCAAGGTAAGGGATTCGCGGTTCGGGGGATTGAAAGAACACTGACATTCTTTCGGTGACGCGAATCCCCG
ATACAACGCAAGGAGGGATT

Downstream 100 bases:

>100_bases
GCGGTCGGCTGCGTTTCGTGTCCAAAGCGTTGGATAACCGCTGATCGGCATGCATCATCGTCGTGGCCCCTTGCGAGGTC
GGCTTGGGGCCACAACGTTC

Product: extracellular solute-binding protein, family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MRKHLVAVVAAAAALLLVAGCGGTSGGSNAESTETTVDGSLNKVVVKGDPSKSPAKANGRKDTFIATINSPSGVFLPGFN
DNGWDGNAQQPIFASLVVTDDSGQYIPDLAEKWDISSDQLTYTFHLRDNLKFSDGSPLTADDVAFSLTLFNDPAYSGGSD
FSDIGIKGVDAYKSGKADSISGIRVIDERTITIETTKANPLTLGILGGQVLSKAYYGKDYQRGHLDYLKDLYGKPLGAGP
YKLSKYVDGQEVRYVANKYYYGGEPKIRNLIFKVTSKDTALSNFQNGETDFDGFSPDKDNLDALKQLGFASVRESTVPDM
SEIWINNLKAPFNDKRVRQALIYGLNRQQIINVAYKGFGQVANVYAAPTQWSYTDKGVNKYKFDPDKAGKLLDEAGWKTG
SDGIREKDGRKLTVRYLTSKDTDETIPIATENYKAIGIDFQPEVLDGDTIIERWTQGGDWDLVGGFRTNGLSDPNDAISE
FVSHDKSINLTGYHNEEADKLAKEGLSTQDKTKRKAIYAELYKVLNNDPPTIPLSYRQSITAWNTRVKGVENYSTGNSDA
ALVLAKLSIE

Sequences:

>Translated_570_residues
MRKHLVAVVAAAAALLLVAGCGGTSGGSNAESTETTVDGSLNKVVVKGDPSKSPAKANGRKDTFIATINSPSGVFLPGFN
DNGWDGNAQQPIFASLVVTDDSGQYIPDLAEKWDISSDQLTYTFHLRDNLKFSDGSPLTADDVAFSLTLFNDPAYSGGSD
FSDIGIKGVDAYKSGKADSISGIRVIDERTITIETTKANPLTLGILGGQVLSKAYYGKDYQRGHLDYLKDLYGKPLGAGP
YKLSKYVDGQEVRYVANKYYYGGEPKIRNLIFKVTSKDTALSNFQNGETDFDGFSPDKDNLDALKQLGFASVRESTVPDM
SEIWINNLKAPFNDKRVRQALIYGLNRQQIINVAYKGFGQVANVYAAPTQWSYTDKGVNKYKFDPDKAGKLLDEAGWKTG
SDGIREKDGRKLTVRYLTSKDTDETIPIATENYKAIGIDFQPEVLDGDTIIERWTQGGDWDLVGGFRTNGLSDPNDAISE
FVSHDKSINLTGYHNEEADKLAKEGLSTQDKTKRKAIYAELYKVLNNDPPTIPLSYRQSITAWNTRVKGVENYSTGNSDA
ALVLAKLSIE
>Mature_570_residues
MRKHLVAVVAAAAALLLVAGCGGTSGGSNAESTETTVDGSLNKVVVKGDPSKSPAKANGRKDTFIATINSPSGVFLPGFN
DNGWDGNAQQPIFASLVVTDDSGQYIPDLAEKWDISSDQLTYTFHLRDNLKFSDGSPLTADDVAFSLTLFNDPAYSGGSD
FSDIGIKGVDAYKSGKADSISGIRVIDERTITIETTKANPLTLGILGGQVLSKAYYGKDYQRGHLDYLKDLYGKPLGAGP
YKLSKYVDGQEVRYVANKYYYGGEPKIRNLIFKVTSKDTALSNFQNGETDFDGFSPDKDNLDALKQLGFASVRESTVPDM
SEIWINNLKAPFNDKRVRQALIYGLNRQQIINVAYKGFGQVANVYAAPTQWSYTDKGVNKYKFDPDKAGKLLDEAGWKTG
SDGIREKDGRKLTVRYLTSKDTDETIPIATENYKAIGIDFQPEVLDGDTIIERWTQGGDWDLVGGFRTNGLSDPNDAISE
FVSHDKSINLTGYHNEEADKLAKEGLSTQDKTKRKAIYAELYKVLNNDPPTIPLSYRQSITAWNTRVKGVENYSTGNSDA
ALVLAKLSIE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=496, Percent_Identity=26.4112903225806, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787762, Length=456, Percent_Identity=27.8508771929825, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1789887, Length=468, Percent_Identity=27.3504273504274, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787551, Length=537, Percent_Identity=23.463687150838, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787495, Length=472, Percent_Identity=25.2118644067797, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789397, Length=470, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787052, Length=455, Percent_Identity=24.8351648351648, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081878, Length=460, Percent_Identity=23.695652173913, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62276; Mature: 62276

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKHLVAVVAAAAALLLVAGCGGTSGGSNAESTETTVDGSLNKVVVKGDPSKSPAKANGR
CCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCC
KDTFIATINSPSGVFLPGFNDNGWDGNAQQPIFASLVVTDDSGQYIPDLAEKWDISSDQL
CCEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCCCE
TYTFHLRDNLKFSDGSPLTADDVAFSLTLFNDPAYSGGSDFSDIGIKGVDAYKSGKADSI
EEEEEEECCCEECCCCCCCHHCEEEEEEEECCCCCCCCCCCHHCCCCCCCHHCCCCCCCC
SGIRVIDERTITIETTKANPLTLGILGGQVLSKAYYGKDYQRGHLDYLKDLYGKPLGAGP
CCEEEEECEEEEEEECCCCCEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
YKLSKYVDGQEVRYVANKYYYGGEPKIRNLIFKVTSKDTALSNFQNGETDFDGFSPDKDN
HHHHHCCCCHHHHEEEHHEEECCCCHHEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCC
LDALKQLGFASVRESTVPDMSEIWINNLKAPFNDKRVRQALIYGLNRQQIINVAYKGFGQ
HHHHHHCCHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VANVYAAPTQWSYTDKGVNKYKFDPDKAGKLLDEAGWKTGSDGIREKDGRKLTVRYLTSK
HHHEEECCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECC
DTDETIPIATENYKAIGIDFQPEVLDGDTIIERWTQGGDWDLVGGFRTNGLSDPNDAISE
CCCCCCCEEECCCEEEECCCCCCEECCHHHHHHHCCCCCEEEECCEECCCCCCHHHHHHH
FVSHDKSINLTGYHNEEADKLAKEGLSTQDKTKRKAIYAELYKVLNNDPPTIPLSYRQSI
HHHCCCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
TAWNTRVKGVENYSTGNSDAALVLAKLSIE
HHHHHEECCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MRKHLVAVVAAAAALLLVAGCGGTSGGSNAESTETTVDGSLNKVVVKGDPSKSPAKANGR
CCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCC
KDTFIATINSPSGVFLPGFNDNGWDGNAQQPIFASLVVTDDSGQYIPDLAEKWDISSDQL
CCEEEEEECCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCCCE
TYTFHLRDNLKFSDGSPLTADDVAFSLTLFNDPAYSGGSDFSDIGIKGVDAYKSGKADSI
EEEEEEECCCEECCCCCCCHHCEEEEEEEECCCCCCCCCCCHHCCCCCCCHHCCCCCCCC
SGIRVIDERTITIETTKANPLTLGILGGQVLSKAYYGKDYQRGHLDYLKDLYGKPLGAGP
CCEEEEECEEEEEEECCCCCEEEEEECHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
YKLSKYVDGQEVRYVANKYYYGGEPKIRNLIFKVTSKDTALSNFQNGETDFDGFSPDKDN
HHHHHCCCCHHHHEEEHHEEECCCCHHEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCC
LDALKQLGFASVRESTVPDMSEIWINNLKAPFNDKRVRQALIYGLNRQQIINVAYKGFGQ
HHHHHHCCHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VANVYAAPTQWSYTDKGVNKYKFDPDKAGKLLDEAGWKTGSDGIREKDGRKLTVRYLTSK
HHHEEECCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECC
DTDETIPIATENYKAIGIDFQPEVLDGDTIIERWTQGGDWDLVGGFRTNGLSDPNDAISE
CCCCCCCEEECCCEEEECCCCCCEECCHHHHHHHCCCCCEEEECCEECCCCCCHHHHHHH
FVSHDKSINLTGYHNEEADKLAKEGLSTQDKTKRKAIYAELYKVLNNDPPTIPLSYRQSI
HHHCCCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
TAWNTRVKGVENYSTGNSDAALVLAKLSIE
HHHHHEECCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]