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The map label for this gene is hutI [H]

Identifier: 213159146

GI number: 213159146

Start: 3979873

End: 3981078

Strand: Reverse

Name: hutI [H]

Synonym: AB57_3857

Alternate gene names: 213159146

Gene position: 3981078-3979873 (Counterclockwise)

Preceding gene: 213159147

Following gene: 213159145

Centisome position: 98.29

GC content: 45.36

Gene sequence:

>1206_bases
ATGAAAAAACTTTGGCAAAACTGCCATATTGCCACCATGCAAAATGGGCAATATTCCTACATTGAAGATGCTGCAATTGT
CACAGAAGGGCATCTCATCCACTGGATTGGAAAACAACAACAACTTCCTGCCGACACTTATTCCGAAACAGTTGACTTAA
ATGGCGCTTGGGTAACCCCGGGGTTCATCGACTGTCATACGCATAGCGTATTTGGTGGTAACCGTAGTGTTGAGTTTGAA
AAGCGCTTACAGGGCGTGAGTTATGCTGAAATTGCTGCAAGTGGTGGCGGTATTGCTAGTACAGTACGCGCAACCCGAGA
AGCCAGCGAAGAACAATTACTGAACTCAGCCCTTAAGCGTATTCGCTGCATGCAACAAGACGGTGTAACCACCATTGAAA
TTAAGTCTGGCTACGGACTCAACTACGAAAACGAGCGCAAAATGCTGCGTGTGATCCGTCAAATTGGTGAAAAATTACCG
ATGACGGTAAAAAGTACGTGTTTAGCTGCACATGCTTTACCGCCAGAGTACAAAGACCAAAGCGACGCTTATATCGAGCA
TATCTGTACAGAAATGCTGCCTAAACTGCATGCTGAAGGCTTAGTCGATGCAGTTGATGCGTTCTGTGAGCATTTAGCAT
TTTCGCCAGCTCAGGTTGAACGTGTTTTTAAAACGGCACAATCATTGGGGCTACCCGTTAAACTTCATGCTGAACAGCTT
TCATCGCTAGGTGGCTCAAGCTTAGCAGCACGTTATCATGCTTTGTCGGCCGACCATTTAGAGTACATGACCGAAGATGA
TGTCAAAGCCATGGCAGAGTCGGGCACGGTTGCAGTGTTATTACCGGGTGCCTTTTATTTATTGCGTGAAACACAATACC
CACCGATTGAAAGTCTTATTAAACATGGCGTGCGTATTGCGCTGTCGAGTGATTTAAATCCGGGTACATCTCCAGCACTT
TCTTTACGTTTAATTCTGAATATGGGCAGTACGTTATTCCGTTTAACGCCTGAGCAAGCATTAGCAGGTATCACTATTCA
TGCTGCACAAGCGCTCGGTTTAGAGCAAACACACGGTAGTTTGGAGCAAGGAAAAGTCGCTGACTTTGTGGCTTGGGATA
TTGAGCATCCATCTGAAATTGTTTACTGGCTGGGCGGAGATTTGCCTAAGCGAGTCGTTCAGCATGGACAAGAAGTTATT
TTTTAA

Upstream 100 bases:

>100_bases
GGGAAAGGAAAGTGAGCCTGTCCAGCAAAACATAGAAATGGAAAGCTAACAAATCAGCTGCCCAATAGTTTTACTGTTGG
GCAGTTTCGAGGATAGGCTA

Downstream 100 bases:

>100_bases
ACGGTGTCACATGAATCACACATTTAAATGGCAAGGCCGACATGATGGCGAGGGTGAGGTACATCAACGTATTCACCATA
TTGTGAACACCACCCAACAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPADTYSETVDLNGAWVTPGFIDCHTHSVFGGNRSVEFE
KRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKRIRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLP
MTVKSTCLAAHALPPEYKDQSDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQL
SSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLIKHGVRIALSSDLNPGTSPAL
SLRLILNMGSTLFRLTPEQALAGITIHAAQALGLEQTHGSLEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVI
F

Sequences:

>Translated_401_residues
MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPADTYSETVDLNGAWVTPGFIDCHTHSVFGGNRSVEFE
KRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKRIRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLP
MTVKSTCLAAHALPPEYKDQSDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQL
SSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLIKHGVRIALSSDLNPGTSPAL
SLRLILNMGSTLFRLTPEQALAGITIHAAQALGLEQTHGSLEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVI
F
>Mature_401_residues
MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPADTYSETVDLNGAWVTPGFIDCHTHSVFGGNRSVEFE
KRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKRIRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLP
MTVKSTCLAAHALPPEYKDQSDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQL
SSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLIKHGVRIALSSDLNPGTSPAL
SLRLILNMGSTLFRLTPEQALAGITIHAAQALGLEQTHGSLEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVI
F

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=366, Percent_Identity=36.3387978142077, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17555004, Length=410, Percent_Identity=33.6585365853659, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 44043; Mature: 44043

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPADTYSETVDLNGAWVTP
CCCHHCCCCEEEEECCCCCEECCCEEEECCCEEEEECCCCCCCCCHHHCEEECCCCEECC
GFIDCHTHSVFGGNRSVEFEKRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKR
CEEECCCCEECCCCCCEEHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLPMTVKSTCLAAHALPPEYKDQ
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
SDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECHHHH
SSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLI
HCCCCHHHHHHHHHCCHHHHHHHCHHHHHHHHCCCCEEEEECCCEEEHHCCCCCCHHHHH
KHGVRIALSSDLNPGTSPALSLRLILNMGSTLFRLTPEQALAGITIHAAQALGLEQTHGS
HCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHEEECHHHHHHCEEEEHHHHHCHHHHCCC
LEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVIF
CCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHCCHHCCC
>Mature Secondary Structure
MKKLWQNCHIATMQNGQYSYIEDAAIVTEGHLIHWIGKQQQLPADTYSETVDLNGAWVTP
CCCHHCCCCEEEEECCCCCEECCCEEEECCCEEEEECCCCCCCCCHHHCEEECCCCEECC
GFIDCHTHSVFGGNRSVEFEKRLQGVSYAEIAASGGGIASTVRATREASEEQLLNSALKR
CEEECCCCEECCCCCCEEHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IRCMQQDGVTTIEIKSGYGLNYENERKMLRVIRQIGEKLPMTVKSTCLAAHALPPEYKDQ
HHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
SDAYIEHICTEMLPKLHAEGLVDAVDAFCEHLAFSPAQVERVFKTAQSLGLPVKLHAEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECHHHH
SSLGGSSLAARYHALSADHLEYMTEDDVKAMAESGTVAVLLPGAFYLLRETQYPPIESLI
HCCCCHHHHHHHHHCCHHHHHHHCHHHHHHHHCCCCEEEEECCCEEEHHCCCCCCHHHHH
KHGVRIALSSDLNPGTSPALSLRLILNMGSTLFRLTPEQALAGITIHAAQALGLEQTHGS
HCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHEEECHHHHHHCEEEEHHHHHCHHHHCCC
LEQGKVADFVAWDIEHPSEIVYWLGGDLPKRVVQHGQEVIF
CCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA