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The map label for this gene is glmU [H]

Identifier: 213159133

GI number: 213159133

Start: 3964231

End: 3965550

Strand: Direct

Name: glmU [H]

Synonym: AB57_3844

Alternate gene names: 213159133

Gene position: 3964231-3965550 (Clockwise)

Preceding gene: 213159132

Following gene: 213159134

Centisome position: 97.87

GC content: 41.89

Gene sequence:

>1320_bases
ATGCGTTCTCAGCTCCCTAAAGTACTACAACCTTTAGCTGGTCGCCCGCTACTAGGACATGTTATTAAAACAGCAAAACA
ACTATTAGCAGAAAACATCATTACCATTTATGGACATGGTGGCGATCACGTAAAAAAGACATTCGCACAAGAAAATATTC
AGTGGGTTGAACAAGCAGAACAGTTAGGGACCGGTCATGCGGTACAGATGACTTTACCGGTACTTCCTAAAGACGGCATT
TCATTAATTTTATACGGTGATGTTCCTTTAGTCCGTCAAACAACGCTTGAACAACTGATTGAAGTATCAAATAAAACCGG
TATTGGCATGATTACTTTACATGTCGATAACCCAACAGGTTATGGCCGTATTGTCCGCCAAGACGGTAAAATCCAGGCGA
TTGTTGAACATAAAGACGCAACCGAAGCTCAGCGTCAAATTCAAGAAATTAACACAGGTATTTACTGTGTCAGCAATGCA
AAACTTCATGAGTGGTTGCCTAAGCTTTCAAATGAAAATGCACAAGGCGAATACTATTTAACTGATATCGTTGCGATGGC
TGTTGCTGATGGTCTAGAAATCGCTTCAATTCAACCAGAGCTCGCATTTGAAGTTGAAGGTGTAAATGACCGCCTGCAAC
TTGCAGCACTTGAGCGGGAATTTCAGAAGCAACAAGCAAAAGAACTTATGCAGCAAGGCGTAACTTTTGCTGATCCTGCG
CGTTTTGATTTACGTGGTACAGTAAAAGTTGGTCATGATGTTCGTATTGATGTGAATGTCATTATTGAAGGTAACTGTGA
ACTCGGTGACTTTGTCGAAATCGGTGCTGGCTGTATCTTAAAAAATACAACCATTGCAGCGGGCACTAAAGTCCAAGCGT
ACAGCGTTTTTGATGGAGCAGTTGTTGGGGAAAATACCCAAATTGGTCCATTCGCACGCTTACGTCCAGGTGCTAAATTG
GCAAACGAAGTACATATCGGCAACTTTGTTGAAGTCAAAAATACAACGATCGGTCTAGGCAGTAAAGCTAACCATTTCAC
CTATTTAGGTGATGCCGAGATCGGTGCTGAATCAAATATTGGGGCAGGTACAATCACCTGCAATTATGATGGTGCAAATA
AACACAAAACCACTATTGGCGATGCAGTTTTTATCGGTTCTAATAGCTCGCTGGTTGCGCCTGTGACTATTGGTAATGGA
GCAACAGTCGGTGCGGGTTCTGTGATTACGAAAGATGTGGCTGAACAAAGTCTCTCCTTTGAGCGTGCTCAACAAATTTC
TAAAGCAAATTATCAACGTCCCCAAAAGCTTAAAAAATAA

Upstream 100 bases:

>100_bases
GCTGCTCTTTGTACACTAATTATTATCCATTTGAGTTAAATCATTCGAGTTATTCATGTCAACTACTGTCATTATTCTTG
CTGCAGGCAAAGGAACGCGA

Downstream 100 bases:

>100_bases
GAGGATTGAAATATGTGTGGTATCGTCGGAGGCGTTGCAGAACGTTGTGTAACCGAGATTTTAATTGAAGGTTTAAAACG
TCTTGAATATCGTGGTTATG

Product: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKKTFAQENIQWVEQAEQLGTGHAVQMTLPVLPKDGI
SLILYGDVPLVRQTTLEQLIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVSNA
KLHEWLPKLSNENAQGEYYLTDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPA
RFDLRGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGAVVGENTQIGPFARLRPGAKL
ANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNG
ATVGAGSVITKDVAEQSLSFERAQQISKANYQRPQKLKK

Sequences:

>Translated_439_residues
MRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKKTFAQENIQWVEQAEQLGTGHAVQMTLPVLPKDGI
SLILYGDVPLVRQTTLEQLIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVSNA
KLHEWLPKLSNENAQGEYYLTDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPA
RFDLRGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGAVVGENTQIGPFARLRPGAKL
ANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNG
ATVGAGSVITKDVAEQSLSFERAQQISKANYQRPQKLKK
>Mature_439_residues
MRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKKTFAQENIQWVEQAEQLGTGHAVQMTLPVLPKDGI
SLILYGDVPLVRQTTLEQLIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVSNA
KLHEWLPKLSNENAQGEYYLTDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPA
RFDLRGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGAVVGENTQIGPFARLRPGAKL
ANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNG
ATVGAGSVITKDVAEQSLSFERAQQISKANYQRPQKLKK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=438, Percent_Identity=55.2511415525114, Blast_Score=504, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47366; Mature: 47366

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKKTFAQENIQWVEQAE
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
QLGTGHAVQMTLPVLPKDGISLILYGDVPLVRQTTLEQLIEVSNKTGIGMITLHVDNPTG
HHCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
YGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVSNAKLHEWLPKLSNENAQGEYYL
CCEEEECCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCCHH
TDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPA
HHHHHHHHHCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RFDLRGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGA
CCCEEEEEEECCEEEEEEEEEEECCCCCCCHHHHCCCEEEECCEEECCCEEEEEEEECCE
VVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNI
EECCCCCCCCHHHCCCCCHHHCEEECCCEEEEECCEEECCCCCCCEEEECCCCCCCCCCC
GAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNGATVGAGSVITKDVAEQSLSF
CCEEEEEECCCCCCCCEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
ERAQQISKANYQRPQKLKK
HHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MRSQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGDHVKKTFAQENIQWVEQAE
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
QLGTGHAVQMTLPVLPKDGISLILYGDVPLVRQTTLEQLIEVSNKTGIGMITLHVDNPTG
HHCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
YGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVSNAKLHEWLPKLSNENAQGEYYL
CCEEEECCCCEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCCCCCCHH
TDIVAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPA
HHHHHHHHHCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RFDLRGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGA
CCCEEEEEEECCEEEEEEEEEEECCCCCCCHHHHCCCEEEECCEEECCCEEEEEEEECCE
VVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNI
EECCCCCCCCHHHCCCCCHHHCEEECCCEEEEECCEEECCCCCCCEEEECCCCCCCCCCC
GAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNGATVGAGSVITKDVAEQSLSF
CCEEEEEECCCCCCCCEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
ERAQQISKANYQRPQKLKK
HHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA