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The map label for this gene is glmS [H]

Identifier: 213159134

GI number: 213159134

Start: 3965563

End: 3967401

Strand: Direct

Name: glmS [H]

Synonym: AB57_3845

Alternate gene names: 213159134

Gene position: 3965563-3967401 (Clockwise)

Preceding gene: 213159133

Following gene: 213159152

Centisome position: 97.9

GC content: 40.13

Gene sequence:

>1839_bases
ATGTGTGGTATCGTCGGAGGCGTTGCAGAACGTTGTGTAACCGAGATTTTAATTGAAGGTTTAAAACGTCTTGAATATCG
TGGTTATGATTCGGCTGGTGTTGCTTTACTGAACAAGCAACAGATTTTACGTGAACGTCGTGTTGGTAAGGTAATCAATC
TTGAAGATGCCGTTGCTGATCAACAACTCACGGGGACAATCGGCATTGCTCATACCCGTTGGGCAACACACGGTAAACCG
ACCGAAAATAATGCTCACCCGCACATGTCAGGCAAGGTAGCAGTCGTTCACAACGGTATTATCGAGAACTATCAAGAGCT
TAAAGATGACCTTCAAGCTTTAGGATATGTATTTACTTCTCAAACAGATACTGAAGTGGTAGCCCATTTAGTTGCAGAAG
CTCTAAAAAATACTGATAGTTTACTTGAAGCAGTAGAATCTGTAGTTCCTCAGCTTAAAGGTGCCTATGCATTAGGTATT
ATTCACAGCGATTACCCAGATGAACTCATTACTGTACGTGAAGGTTCACCACTTGTAATTGGTGTGGGTATTGGCGAGAA
CTTTATCAGTTCAGACCAATTGGCTCTTTTACCAGTAACAAACCGTTTTATTTACTTAGAAGAAGGCGATATTGCCCGTC
TTACTCGTACTTCAATTGAAGTATTTGTAAAAGGTGAACGTGTTGAACGTCCAGTTAAAGAACTTGATGCAACTGTAAGC
AGTGCTTCAAAAGGTGAATATAAACACTACATGCTCAAAGAAATTTATGAGCAGCCTGAAGCAATCAAACAAACAATTTC
TCAAGCGCTTGATGGCAACAATTTACGTGATGATTTCTTGAAAGATGCTGATGCAGATTTCAGTAAACTTCAAAGTGTTC
AAATTATTGCTTGTGGTACAAGTTATCACTCAGGAATGATCGCTAAATATTGGTTTGAACAGTTAATTGGCGTGCCTTGC
CAAGTTGAAATCGCAAGTGAGTTCCGCTATCGCACTCCTGTAATTGTTGAAAATACACTTTATATTTGTATTTCACAGTC
AGGTGAAACTGCTGATACTTTAGCTGCACTACGTGAAACTCAAAAACGTGCTAAAGCAAACAATATCGATATTCAGACTT
TGACGATCTGTAACGTTGCGACGTCTTCAATGGTTCGTGAAACTGATCATCACTTATTGACGCTTGCTGGTCCTGAAATT
GGTGTTGCATCAACTAAAGCGTTCACGACTCAGCTTGCTGCATTAATGTTGTTAATCTTGAAAATTGGTCAAGTTAAACA
ACGTATTAGCAATGTGATGATTGAAGAGCTTGCTCGTGAATTGTGGCACAGCCCGAAAGTCATTCTTGATACGCTTAAGC
AAGATGCTGAAATTTTACGTTTATCAGAATTGTTCGTTGAAAAACAACACTGTTTATTCTTAGGCCGTGGCACACACTAT
CCAATCGCTTTGGAAGGCGCATTAAAGCTTAAAGAAATTTCATATATTCACGCAGAAGGTTATGCGGCTGGTGAGTTAAA
ACATGGCCCATTGGCACTTGTTGATACTGAAATGCCAATCGTGATTCTTGCACCAAATGACGAAATGCTTGATAAGCTTA
AGTCGAATATGGAGGAAGTTCAGGCGCGTGGCGGTGAGTTATTCGTTTTTGCTGATGAAAATAGTGGTGTAGTCGAAAAA
GATCGTCAACACGTTGTACAAATTCCAGCAGTAAATGAATGGCTTGCACCAATCATTTATAGCGTACCAGTTCAGTTATT
GTCTTATCACGTTGCTGTATTACGTGGTACAGACGTTGACCAGCCACGTAACTTGGCGAAGTCAGTAACTGTAGAGTAA

Upstream 100 bases:

>100_bases
AGATGTGGCTGAACAAAGTCTCTCCTTTGAGCGTGCTCAACAAATTTCTAAAGCAAATTATCAACGTCCCCAAAAGCTTA
AAAAATAAGAGGATTGAAAT

Downstream 100 bases:

>100_bases
TTCAAAAAAGATCATTATTAAGGCATCACCTGCTTTAATAATTGATTGATTAAGCCCGATATGCATTAGTTGCTTATCGG
GCTTTTTTATTGTCTGATTC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MCGIVGGVAERCVTEILIEGLKRLEYRGYDSAGVALLNKQQILRERRVGKVINLEDAVADQQLTGTIGIAHTRWATHGKP
TENNAHPHMSGKVAVVHNGIIENYQELKDDLQALGYVFTSQTDTEVVAHLVAEALKNTDSLLEAVESVVPQLKGAYALGI
IHSDYPDELITVREGSPLVIGVGIGENFISSDQLALLPVTNRFIYLEEGDIARLTRTSIEVFVKGERVERPVKELDATVS
SASKGEYKHYMLKEIYEQPEAIKQTISQALDGNNLRDDFLKDADADFSKLQSVQIIACGTSYHSGMIAKYWFEQLIGVPC
QVEIASEFRYRTPVIVENTLYICISQSGETADTLAALRETQKRAKANNIDIQTLTICNVATSSMVRETDHHLLTLAGPEI
GVASTKAFTTQLAALMLLILKIGQVKQRISNVMIEELARELWHSPKVILDTLKQDAEILRLSELFVEKQHCLFLGRGTHY
PIALEGALKLKEISYIHAEGYAAGELKHGPLALVDTEMPIVILAPNDEMLDKLKSNMEEVQARGGELFVFADENSGVVEK
DRQHVVQIPAVNEWLAPIIYSVPVQLLSYHVAVLRGTDVDQPRNLAKSVTVE

Sequences:

>Translated_612_residues
MCGIVGGVAERCVTEILIEGLKRLEYRGYDSAGVALLNKQQILRERRVGKVINLEDAVADQQLTGTIGIAHTRWATHGKP
TENNAHPHMSGKVAVVHNGIIENYQELKDDLQALGYVFTSQTDTEVVAHLVAEALKNTDSLLEAVESVVPQLKGAYALGI
IHSDYPDELITVREGSPLVIGVGIGENFISSDQLALLPVTNRFIYLEEGDIARLTRTSIEVFVKGERVERPVKELDATVS
SASKGEYKHYMLKEIYEQPEAIKQTISQALDGNNLRDDFLKDADADFSKLQSVQIIACGTSYHSGMIAKYWFEQLIGVPC
QVEIASEFRYRTPVIVENTLYICISQSGETADTLAALRETQKRAKANNIDIQTLTICNVATSSMVRETDHHLLTLAGPEI
GVASTKAFTTQLAALMLLILKIGQVKQRISNVMIEELARELWHSPKVILDTLKQDAEILRLSELFVEKQHCLFLGRGTHY
PIALEGALKLKEISYIHAEGYAAGELKHGPLALVDTEMPIVILAPNDEMLDKLKSNMEEVQARGGELFVFADENSGVVEK
DRQHVVQIPAVNEWLAPIIYSVPVQLLSYHVAVLRGTDVDQPRNLAKSVTVE
>Mature_612_residues
MCGIVGGVAERCVTEILIEGLKRLEYRGYDSAGVALLNKQQILRERRVGKVINLEDAVADQQLTGTIGIAHTRWATHGKP
TENNAHPHMSGKVAVVHNGIIENYQELKDDLQALGYVFTSQTDTEVVAHLVAEALKNTDSLLEAVESVVPQLKGAYALGI
IHSDYPDELITVREGSPLVIGVGIGENFISSDQLALLPVTNRFIYLEEGDIARLTRTSIEVFVKGERVERPVKELDATVS
SASKGEYKHYMLKEIYEQPEAIKQTISQALDGNNLRDDFLKDADADFSKLQSVQIIACGTSYHSGMIAKYWFEQLIGVPC
QVEIASEFRYRTPVIVENTLYICISQSGETADTLAALRETQKRAKANNIDIQTLTICNVATSSMVRETDHHLLTLAGPEI
GVASTKAFTTQLAALMLLILKIGQVKQRISNVMIEELARELWHSPKVILDTLKQDAEILRLSELFVEKQHCLFLGRGTHY
PIALEGALKLKEISYIHAEGYAAGELKHGPLALVDTEMPIVILAPNDEMLDKLKSNMEEVQARGGELFVFADENSGVVEK
DRQHVVQIPAVNEWLAPIIYSVPVQLLSYHVAVLRGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=693, Percent_Identity=38.2395382395382, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI4826742, Length=690, Percent_Identity=37.1014492753623, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI29570798, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1790167, Length=615, Percent_Identity=57.5609756097561, Blast_Score=714, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082251, Length=317, Percent_Identity=20.5047318611987, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=438, Percent_Identity=39.2694063926941, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17532899, Length=441, Percent_Identity=37.4149659863946, Blast_Score=272, Evalue=4e-73,
Organism=Caenorhabditis elegans, GI17532897, Length=441, Percent_Identity=37.4149659863946, Blast_Score=271, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6322745, Length=455, Percent_Identity=37.3626373626374, Blast_Score=265, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323731, Length=441, Percent_Identity=31.7460317460317, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=38.5365853658537, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357745, Length=696, Percent_Identity=36.7816091954023, Blast_Score=405, Evalue=1e-113,
Organism=Drosophila melanogaster, GI28573187, Length=266, Percent_Identity=25.187969924812, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67663; Mature: 67663

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGGVAERCVTEILIEGLKRLEYRGYDSAGVALLNKQQILRERRVGKVINLEDAVAD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCEECCHHHHCC
QQLTGTIGIAHTRWATHGKPTENNAHPHMSGKVAVVHNGIIENYQELKDDLQALGYVFTS
CHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCC
QTDTEVVAHLVAEALKNTDSLLEAVESVVPQLKGAYALGIIHSDYPDELITVREGSPLVI
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCEEE
GVGIGENFISSDQLALLPVTNRFIYLEEGDIARLTRTSIEVFVKGERVERPVKELDATVS
EEECCCCCCCCCCEEEEEECCEEEEEECCCCHHHHHCEEEEEEECHHHHHHHHHHHHHHH
SASKGEYKHYMLKEIYEQPEAIKQTISQALDGNNLRDDFLKDADADFSKLQSVQIIACGT
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHCCCEEEEEECC
SYHSGMIAKYWFEQLIGVPCQVEIASEFRYRTPVIVENTLYICISQSGETADTLAALRET
CCCCCHHHHHHHHHHHCCCCEEEEHHHCCCCCCEEEECEEEEEEECCCCHHHHHHHHHHH
QKRAKANNIDIQTLTICNVATSSMVRETDHHLLTLAGPEIGVASTKAFTTQLAALMLLIL
HHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
KIGQVKQRISNVMIEELARELWHSPKVILDTLKQDAEILRLSELFVEKQHCLFLGRGTHY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
PIALEGALKLKEISYIHAEGYAAGELKHGPLALVDTEMPIVILAPNDEMLDKLKSNMEEV
CEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHH
QARGGELFVFADENSGVVEKDRQHVVQIPAVNEWLAPIIYSVPVQLLSYHVAVLRGTDVD
HHCCCEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QPRNLAKSVTVE
CHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGGVAERCVTEILIEGLKRLEYRGYDSAGVALLNKQQILRERRVGKVINLEDAVAD
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCEECCHHHHCC
QQLTGTIGIAHTRWATHGKPTENNAHPHMSGKVAVVHNGIIENYQELKDDLQALGYVFTS
CHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCC
QTDTEVVAHLVAEALKNTDSLLEAVESVVPQLKGAYALGIIHSDYPDELITVREGSPLVI
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCEEE
GVGIGENFISSDQLALLPVTNRFIYLEEGDIARLTRTSIEVFVKGERVERPVKELDATVS
EEECCCCCCCCCCEEEEEECCEEEEEECCCCHHHHHCEEEEEEECHHHHHHHHHHHHHHH
SASKGEYKHYMLKEIYEQPEAIKQTISQALDGNNLRDDFLKDADADFSKLQSVQIIACGT
CCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHCCCEEEEEECC
SYHSGMIAKYWFEQLIGVPCQVEIASEFRYRTPVIVENTLYICISQSGETADTLAALRET
CCCCCHHHHHHHHHHHCCCCEEEEHHHCCCCCCEEEECEEEEEEECCCCHHHHHHHHHHH
QKRAKANNIDIQTLTICNVATSSMVRETDHHLLTLAGPEIGVASTKAFTTQLAALMLLIL
HHHHHCCCCCEEEEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
KIGQVKQRISNVMIEELARELWHSPKVILDTLKQDAEILRLSELFVEKQHCLFLGRGTHY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
PIALEGALKLKEISYIHAEGYAAGELKHGPLALVDTEMPIVILAPNDEMLDKLKSNMEEV
CEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHH
QARGGELFVFADENSGVVEKDRQHVVQIPAVNEWLAPIIYSVPVQLLSYHVAVLRGTDVD
HHCCCEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QPRNLAKSVTVE
CHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA