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The map label for this gene is yoeA [H]

Identifier: 213159114

GI number: 213159114

Start: 3945720

End: 3947087

Strand: Direct

Name: yoeA [H]

Synonym: AB57_3824

Alternate gene names: 213159114

Gene position: 3945720-3947087 (Clockwise)

Preceding gene: 213159113

Following gene: 213159116

Centisome position: 97.41

GC content: 41.15

Gene sequence:

>1368_bases
ATGCCACCAAGACAGTCTTTAATTCATCAGCAAAATCTTTGGAAAACATTTTTTGTTTTCTTATTGCCCCTGATTGCAAC
CAATATCTTGCAAAACCTGTCCGGTACCATTAACACCATCTTTGTTGGACAAATGATGGGGGTCGATGCCATTGCTGCAG
TTTCTGTATATTTCCCCATTTTGTTTTTACTGCTTGCGTTTATTATCGGTATTTCAACGGGTACCACTGTTTTAGTGGGT
CAGGCTTGGGGCGCACAAGACATAGAAAAGGTTCAAAGTGTGGTGGGTTCTACCCTATTTATGACCATCATTGGCGGTAT
CATTACCGCAATCATTGGTGTGTTTTTTGCCCACGACATTTTAGAACTTTTAGGTACGGACCCGAAGGTGATGCACCTCT
CTTTGCCTTATGTGCAATGGATGTTGGCAGGTAGTCCTCTTCTCTTTGTTTATATTATCTATACCTCAATTTTACGTGGT
GTAGGAGATAGTACTACCCCTTTACTTGCACTGGCTTTAACCAGCGTGATCGGCGTAATTATTACACCAATTCTGCTGAA
AGGTTATTTTGGCTTTCCTGCCCTCGGTATTATTGCACCGGCTATAGCGTCAATTATTAGTTATATTGCCATCTTAATTT
TTCTTGCGATTTATCTAAATAAGAAAAAGCATCCACTTCGGCCAAACCGTCAGCTTTTGCAACATATCCGTCATAATTCG
GCATTGAGTAAAATCATTTTACGCCTAGGTGTTCCAACCGGTATTCAAATGATTACCACTTCAATGGCCGGTTTAGTCAT
TGTGGGTTTAGTGAACCGTTTCGGAGCTCATGCCACAGCTGCGTATGGTGCCGTGAATCAGGTACTCAACTATATTCAGT
TTCCAGCGATTTCGATCTCTATCGCGGCCTCAATCTTTGCAGCACAAGCGATTGGTGCTGGTAAGTCGGACCTACTCGCA
CGTGTTACACGCACCGCTTTGGGAATGAACTTTTTATTTACAGGTGCCTTAATTGCACTCGGCTATCTATTTTCAAAATA
TTTGATGGCTTTATTCATCACAGATCCAACTGTGGTGGTGTTAGGGCAACAGCTTTTATTTATTGTACTTTGGGCAATTT
TATTCTTTGGTGCAGGTGCCATTTTTGCATCAATTATGCGTGCCAGTGGGACTGTAACCGTACCAATGCTGATTAACATC
TCTGCCATTTTATTTATTGAAATGCCATGCGCTTACTGGTTTAGTTCGATGTGGGGGCTTAAAGGCATTTGGGTCGCCTA
TGCCTTGGCATTTGTCAGTTTATGTATTATTCAAGGCTTGTATTATCAATTTATTTGGAAGAAAAAGAAGATCAAAGTTC
TTATTTAG

Upstream 100 bases:

>100_bases
TAGTCACTTAGCATAGTAAAAATACTACAAGAAGTTCCCTACAACTATGCTAAGTTGAATATCCGACCCGCTCATCAAAG
AGATGGGCGATGGAGAATAC

Downstream 100 bases:

>100_bases
AATGCATTAAACCTTATAAAAAAAGCCATCAATTGATGGCTTTTTTCTTTTAAATCTTATTTCATCCATTTGGTTACAAT
GGTTGAAGCACGTTGATACC

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MPPRQSLIHQQNLWKTFFVFLLPLIATNILQNLSGTINTIFVGQMMGVDAIAAVSVYFPILFLLLAFIIGISTGTTVLVG
QAWGAQDIEKVQSVVGSTLFMTIIGGIITAIIGVFFAHDILELLGTDPKVMHLSLPYVQWMLAGSPLLFVYIIYTSILRG
VGDSTTPLLALALTSVIGVIITPILLKGYFGFPALGIIAPAIASIISYIAILIFLAIYLNKKKHPLRPNRQLLQHIRHNS
ALSKIILRLGVPTGIQMITTSMAGLVIVGLVNRFGAHATAAYGAVNQVLNYIQFPAISISIAASIFAAQAIGAGKSDLLA
RVTRTALGMNFLFTGALIALGYLFSKYLMALFITDPTVVVLGQQLLFIVLWAILFFGAGAIFASIMRASGTVTVPMLINI
SAILFIEMPCAYWFSSMWGLKGIWVAYALAFVSLCIIQGLYYQFIWKKKKIKVLI

Sequences:

>Translated_455_residues
MPPRQSLIHQQNLWKTFFVFLLPLIATNILQNLSGTINTIFVGQMMGVDAIAAVSVYFPILFLLLAFIIGISTGTTVLVG
QAWGAQDIEKVQSVVGSTLFMTIIGGIITAIIGVFFAHDILELLGTDPKVMHLSLPYVQWMLAGSPLLFVYIIYTSILRG
VGDSTTPLLALALTSVIGVIITPILLKGYFGFPALGIIAPAIASIISYIAILIFLAIYLNKKKHPLRPNRQLLQHIRHNS
ALSKIILRLGVPTGIQMITTSMAGLVIVGLVNRFGAHATAAYGAVNQVLNYIQFPAISISIAASIFAAQAIGAGKSDLLA
RVTRTALGMNFLFTGALIALGYLFSKYLMALFITDPTVVVLGQQLLFIVLWAILFFGAGAIFASIMRASGTVTVPMLINI
SAILFIEMPCAYWFSSMWGLKGIWVAYALAFVSLCIIQGLYYQFIWKKKKIKVLI
>Mature_454_residues
PPRQSLIHQQNLWKTFFVFLLPLIATNILQNLSGTINTIFVGQMMGVDAIAAVSVYFPILFLLLAFIIGISTGTTVLVGQ
AWGAQDIEKVQSVVGSTLFMTIIGGIITAIIGVFFAHDILELLGTDPKVMHLSLPYVQWMLAGSPLLFVYIIYTSILRGV
GDSTTPLLALALTSVIGVIITPILLKGYFGFPALGIIAPAIASIISYIAILIFLAIYLNKKKHPLRPNRQLLQHIRHNSA
LSKIILRLGVPTGIQMITTSMAGLVIVGLVNRFGAHATAAYGAVNQVLNYIQFPAISISIAASIFAAQAIGAGKSDLLAR
VTRTALGMNFLFTGALIALGYLFSKYLMALFITDPTVVVLGQQLLFIVLWAILFFGAGAIFASIMRASGTVTVPMLINIS
AILFIEMPCAYWFSSMWGLKGIWVAYALAFVSLCIIQGLYYQFIWKKKKIKVLI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=463, Percent_Identity=21.3822894168467, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49420; Mature: 49289

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPRQSLIHQQNLWKTFFVFLLPLIATNILQNLSGTINTIFVGQMMGVDAIAAVSVYFPI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFLLLAFIIGISTGTTVLVGQAWGAQDIEKVQSVVGSTLFMTIIGGIITAIIGVFFAHDI
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELLGTDPKVMHLSLPYVQWMLAGSPLLFVYIIYTSILRGVGDSTTPLLALALTSVIGVI
HHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ITPILLKGYFGFPALGIIAPAIASIISYIAILIFLAIYLNKKKHPLRPNRQLLQHIRHNS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALSKIILRLGVPTGIQMITTSMAGLVIVGLVNRFGAHATAAYGAVNQVLNYIQFPAISIS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
IAASIFAAQAIGAGKSDLLARVTRTALGMNFLFTGALIALGYLFSKYLMALFITDPTVVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LGQQLLFIVLWAILFFGAGAIFASIMRASGTVTVPMLINISAILFIEMPCAYWFSSMWGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHCCH
KGIWVAYALAFVSLCIIQGLYYQFIWKKKKIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure 
PPRQSLIHQQNLWKTFFVFLLPLIATNILQNLSGTINTIFVGQMMGVDAIAAVSVYFPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LFLLLAFIIGISTGTTVLVGQAWGAQDIEKVQSVVGSTLFMTIIGGIITAIIGVFFAHDI
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELLGTDPKVMHLSLPYVQWMLAGSPLLFVYIIYTSILRGVGDSTTPLLALALTSVIGVI
HHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ITPILLKGYFGFPALGIIAPAIASIISYIAILIFLAIYLNKKKHPLRPNRQLLQHIRHNS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALSKIILRLGVPTGIQMITTSMAGLVIVGLVNRFGAHATAAYGAVNQVLNYIQFPAISIS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHH
IAASIFAAQAIGAGKSDLLARVTRTALGMNFLFTGALIALGYLFSKYLMALFITDPTVVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LGQQLLFIVLWAILFFGAGAIFASIMRASGTVTVPMLINISAILFIEMPCAYWFSSMWGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHCCH
KGIWVAYALAFVSLCIIQGLYYQFIWKKKKIKVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]