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The map label for this gene is ybdL [H]

Identifier: 213159113

GI number: 213159113

Start: 3944459

End: 3945613

Strand: Direct

Name: ybdL [H]

Synonym: AB57_3823

Alternate gene names: 213159113

Gene position: 3944459-3945613 (Clockwise)

Preceding gene: 213159112

Following gene: 213159114

Centisome position: 97.38

GC content: 42.68

Gene sequence:

>1155_bases
ATGCTACAGCTTCAGTCCAAATTTCCCGCACAAGGGGTGACTATTTTTAGTACGATGACGGCAATGGCACAGCGCTTGGG
TGCACTTAACCTTTCACAAGGTTTCCCGGATTTTCCTGCACCCCCTGCTTTGCTCGAAGCCCTATCTCAGGCAACTTTGG
CTGGACACAATCAGTATCCACCTGGTGATGGCATTCTCGCACTGCGTGAACAGCTCGCTTTACAATTTCAACAGCGTGAC
CAGCTTCAACTTGATCCTGTAACTCAAATCACGATTACGCCCGGTGCAACTATAGCAATTTTCTGTGCCATACAAGCTTG
TATCAACACAGGTGATGAAGTCATTATTTTTGACCCGAGTTATGACAGCTATGGACCTTCTGTCGAGTTAGCAGGTGGTA
AAGCGGTACATATTGCCTTGCAAGCACCTGACTTTAAGGTGAACTGGCAACAAGTTAAAGATCGAATTAACGATAAAACC
CGTATGATTGTGGTAAATACCCCCCACAATCCAACAGGTACAATCTGGTCCGAACAAGACTGGTTAGAACTGATCGCACT
AATTCAGGATAAAAATATTGTAGTTTTATCTGATGAAGTCTACGAACACTTAGTTTTTGATGGTCAACAGCACTTTAGCG
CATTGCATTTCCCTGAGCTTAGAGAACGTAGTTTTGTGATTGGTTCTTTTGGAAAAACCTTCCATGTCACAGGCTGGAAA
ACCGGTTACTGCGTTGCTTCACCTGATTTAATGCGTTTGTTCCGCCAGATTTATCAATATGTTAATTTCTGTGGCACAAC
ACCTTGTCAGATTGCGCTTGCGCAATATATGCAGCAACACCCAGAACATATTCAGGAACTTTCACAGTTTTATCAGACTA
AACGAGACCGATTTAATCAGGCGATTCACAATAGCCGTTTTTTGCTTAAATCATCGCAAGGAACTTATTTCCAAAACCTT
GATTACAGCCAGATTAGACCTGACTTAAACGATGTGGAAATGTGCCAGTTTCTTGCCGAGCAACATAAGATTGTGGCTAT
TCCTGTTTCGGTGTTTTACCAACAAGCCCCAGAGTCTTTACGCCTAATACGGTTCTGCTTTGCAAAAAATGATGAAACAC
TGCAAAAAGCAGGAGAAATTCTGAATCAATGTTAA

Upstream 100 bases:

>100_bases
TGGCGTTGTAGTAGGTGCATTTATCGGCTTAACTCTAGGTGTAATACGAGCAGCGATTGAATCAATTTTATAACGTTAAT
AATTTCTTTAAGAGAACAAT

Downstream 100 bases:

>100_bases
TAAATTTAGTCACTTAGCATAGTAAAAATACTACAAGAAGTTCCCTACAACTATGCTAAGTTGAATATCCGACCCGCTCA
TCAAAGAGATGGGCGATGGA

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MLQLQSKFPAQGVTIFSTMTAMAQRLGALNLSQGFPDFPAPPALLEALSQATLAGHNQYPPGDGILALREQLALQFQQRD
QLQLDPVTQITITPGATIAIFCAIQACINTGDEVIIFDPSYDSYGPSVELAGGKAVHIALQAPDFKVNWQQVKDRINDKT
RMIVVNTPHNPTGTIWSEQDWLELIALIQDKNIVVLSDEVYEHLVFDGQQHFSALHFPELRERSFVIGSFGKTFHVTGWK
TGYCVASPDLMRLFRQIYQYVNFCGTTPCQIALAQYMQQHPEHIQELSQFYQTKRDRFNQAIHNSRFLLKSSQGTYFQNL
DYSQIRPDLNDVEMCQFLAEQHKIVAIPVSVFYQQAPESLRLIRFCFAKNDETLQKAGEILNQC

Sequences:

>Translated_384_residues
MLQLQSKFPAQGVTIFSTMTAMAQRLGALNLSQGFPDFPAPPALLEALSQATLAGHNQYPPGDGILALREQLALQFQQRD
QLQLDPVTQITITPGATIAIFCAIQACINTGDEVIIFDPSYDSYGPSVELAGGKAVHIALQAPDFKVNWQQVKDRINDKT
RMIVVNTPHNPTGTIWSEQDWLELIALIQDKNIVVLSDEVYEHLVFDGQQHFSALHFPELRERSFVIGSFGKTFHVTGWK
TGYCVASPDLMRLFRQIYQYVNFCGTTPCQIALAQYMQQHPEHIQELSQFYQTKRDRFNQAIHNSRFLLKSSQGTYFQNL
DYSQIRPDLNDVEMCQFLAEQHKIVAIPVSVFYQQAPESLRLIRFCFAKNDETLQKAGEILNQC
>Mature_384_residues
MLQLQSKFPAQGVTIFSTMTAMAQRLGALNLSQGFPDFPAPPALLEALSQATLAGHNQYPPGDGILALREQLALQFQQRD
QLQLDPVTQITITPGATIAIFCAIQACINTGDEVIIFDPSYDSYGPSVELAGGKAVHIALQAPDFKVNWQQVKDRINDKT
RMIVVNTPHNPTGTIWSEQDWLELIALIQDKNIVVLSDEVYEHLVFDGQQHFSALHFPELRERSFVIGSFGKTFHVTGWK
TGYCVASPDLMRLFRQIYQYVNFCGTTPCQIALAQYMQQHPEHIQELSQFYQTKRDRFNQAIHNSRFLLKSSQGTYFQNL
DYSQIRPDLNDVEMCQFLAEQHKIVAIPVSVFYQQAPESLRLIRFCFAKNDETLQKAGEILNQC

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=34.7607052896725, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=34.5088161209068, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=33.4177215189873, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=33.4177215189873, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=30.0254452926209, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4507369, Length=211, Percent_Identity=24.1706161137441, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=46.9656992084433, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=21.0666666666667, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788627, Length=220, Percent_Identity=29.0909090909091, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787710, Length=339, Percent_Identity=23.0088495575221, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787909, Length=355, Percent_Identity=23.0985915492958, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=405, Percent_Identity=33.3333333333333, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71994472, Length=405, Percent_Identity=33.3333333333333, Blast_Score=229, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17567369, Length=405, Percent_Identity=29.6296296296296, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=347, Percent_Identity=21.6138328530259, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=383, Percent_Identity=29.5039164490862, Blast_Score=172, Evalue=8e-44,
Organism=Drosophila melanogaster, GI28573069, Length=400, Percent_Identity=30.5, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24646114, Length=400, Percent_Identity=30.5, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI28573067, Length=400, Percent_Identity=30.5, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI28573065, Length=400, Percent_Identity=30.5, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI18859735, Length=259, Percent_Identity=25.4826254826255, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 43478; Mature: 43478

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLQSKFPAQGVTIFSTMTAMAQRLGALNLSQGFPDFPAPPALLEALSQATLAGHNQYP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PGDGILALREQLALQFQQRDQLQLDPVTQITITPGATIAIFCAIQACINTGDEVIIFDPS
CCCCHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCC
YDSYGPSVELAGGKAVHIALQAPDFKVNWQQVKDRINDKTRMIVVNTPHNPTGTIWSEQD
CCCCCCEEEECCCEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHH
WLELIALIQDKNIVVLSDEVYEHLVFDGQQHFSALHFPELRERSFVIGSFGKTFHVTGWK
HHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHCCCCHHHHCEEEEECCCCEEEECCCC
TGYCVASPDLMRLFRQIYQYVNFCGTTPCQIALAQYMQQHPEHIQELSQFYQTKRDRFNQ
CCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
AIHNSRFLLKSSQGTYFQNLDYSQIRPDLNDVEMCQFLAEQHKIVAIPVSVFYQQAPESL
HHHCCEEEEECCCCCEEECCCHHHHCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHCHHHH
RLIRFCFAKNDETLQKAGEILNQC
HHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLQLQSKFPAQGVTIFSTMTAMAQRLGALNLSQGFPDFPAPPALLEALSQATLAGHNQYP
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
PGDGILALREQLALQFQQRDQLQLDPVTQITITPGATIAIFCAIQACINTGDEVIIFDPS
CCCCHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCC
YDSYGPSVELAGGKAVHIALQAPDFKVNWQQVKDRINDKTRMIVVNTPHNPTGTIWSEQD
CCCCCCEEEECCCEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHH
WLELIALIQDKNIVVLSDEVYEHLVFDGQQHFSALHFPELRERSFVIGSFGKTFHVTGWK
HHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHCCCCHHHHCEEEEECCCCEEEECCCC
TGYCVASPDLMRLFRQIYQYVNFCGTTPCQIALAQYMQQHPEHIQELSQFYQTKRDRFNQ
CCEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
AIHNSRFLLKSSQGTYFQNLDYSQIRPDLNDVEMCQFLAEQHKIVAIPVSVFYQQAPESL
HHHCCEEEEECCCCCEEECCCHHHHCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHCHHHH
RLIRFCFAKNDETLQKAGEILNQC
HHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]