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The map label for this gene is pdxH

Identifier: 213159058

GI number: 213159058

Start: 3884440

End: 3885096

Strand: Reverse

Name: pdxH

Synonym: AB57_3768

Alternate gene names: 213159058

Gene position: 3885096-3884440 (Counterclockwise)

Preceding gene: 213159059

Following gene: 213159057

Centisome position: 95.92

GC content: 43.53

Gene sequence:

>657_bases
ATGAGTGATGTCATTAAAGATTTAAGTGAATTGCGCTTAAGCTATGAACAAGGCGAGTTGTATGAGACTCAAGTTGCTAG
CAATCCCCACGAGCAATTTCTAGGTTGGTTTAATCATGCCTTAGCAGCTAACTTGCATGAACCGTATGCAATGTCATTAG
CAACTGCGAGTGCTAGTGGTCGTCCGCATGTCAGAACTGTGTTGTTACGCGGTGCGACAGAAGCAGGTTATGATTTCTAT
ACCAACTATGACAGTCAAAAAGGTATAGATTTGGCAGAAAATCCATATGCTGAATTGTTATTTTATTGGCCAAGTCTAGA
GCGTCAGGTACGAGTAGGTGGGCATGTTGTAAAAATTCCTGAACAGGAATCTACAGACTACTATCATAAACGTCCACGTG
ATAGCCAGATTGCAGCTCATATCAGTACCCCCCAAAGTGGCAAAATTGAAAGTCGCGAGTTGTTACAACAGCGTTTTCAA
GACTTGCAACAACAAGTTCAAAGCCGTGAAGTACTCGATAAGCCGGAGTTCTGGGGCGGATATCGTCTACAGCCGGATTA
TTATGAGTTCTGGCAAGGGCGACCAAATCGTTTACATGACCGCTTGAGTTATGAAAAAATCGACGGTCAATGGACGTTGC
ACCGACTGATGCCTTAA

Upstream 100 bases:

>100_bases
GTCATGGTTGAAGGTGATAACGAGCAAGAAGTGAAAACTTTAGCTGAACATTTAGCAAATGCAGTTCGTTCACAGGCACA
AGTCGCATAAGGTGTATGGC

Downstream 100 bases:

>100_bases
ATGACAAAAATACAAATTAAACAAAGACCTTTATTGACACGCCCTGAACAGTTTCAGGGCGTGCCTCCGTTTATTGCCGA
AATTTTGGCAAGACGGGGCG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHEPYAMSLATASASGRPHVRTVLLRGATEAGYDFY
TNYDSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIPEQESTDYYHKRPRDSQIAAHISTPQSGKIESRELLQQRFQ
DLQQQVQSREVLDKPEFWGGYRLQPDYYEFWQGRPNRLHDRLSYEKIDGQWTLHRLMP

Sequences:

>Translated_218_residues
MSDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHEPYAMSLATASASGRPHVRTVLLRGATEAGYDFY
TNYDSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIPEQESTDYYHKRPRDSQIAAHISTPQSGKIESRELLQQRFQ
DLQQQVQSREVLDKPEFWGGYRLQPDYYEFWQGRPNRLHDRLSYEKIDGQWTLHRLMP
>Mature_217_residues
SDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHEPYAMSLATASASGRPHVRTVLLRGATEAGYDFYT
NYDSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIPEQESTDYYHKRPRDSQIAAHISTPQSGKIESRELLQQRFQD
LQQQVQSREVLDKPEFWGGYRLQPDYYEFWQGRPNRLHDRLSYEKIDGQWTLHRLMP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=204, Percent_Identity=45.0980392156863, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI1787926, Length=217, Percent_Identity=40.5529953917051, Blast_Score=165, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17553712, Length=221, Percent_Identity=39.3665158371041, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=36.8421052631579, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI45551845, Length=206, Percent_Identity=41.2621359223301, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24644901, Length=206, Percent_Identity=41.747572815534, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24644903, Length=173, Percent_Identity=29.4797687861272, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_ACIB5 (B7ICC6)

Other databases:

- EMBL:   CP001182
- RefSeq:   YP_002321056.1
- ProteinModelPortal:   B7ICC6
- SMR:   B7ICC6
- GeneID:   7043749
- GenomeReviews:   CP001182_GR
- KEGG:   abn:AB57_3768
- HOGENOM:   HBG327559
- OMA:   FTFFTNY
- ProtClustDB:   CLSK2307561
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190
- TIGRFAMs:   TIGR00558

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 25475; Mature: 25343

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 65-65 BINDING 68-68 BINDING 70-70 BINDING 87-87 BINDING 127-127 BINDING 131-131 BINDING 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHEPYAMSLATASASG
CCHHHHHHHHHHHHHHCCCEEHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
RPHVRTVLLRGATEAGYDFYTNYDSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIP
CCHHEEHEECCCCCCCCHHEECCCCCCCCCCCCCCHHHEEEECCCCCCCEECCCEEEECC
EQESTDYYHKRPRDSQIAAHISTPQSGKIESRELLQQRFQDLQQQVQSREVLDKPEFWGG
CCCCCCHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YRLQPDYYEFWQGRPNRLHDRLSYEKIDGQWTLHRLMP
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCEEHHCCCC
>Mature Secondary Structure 
SDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHEPYAMSLATASASG
CHHHHHHHHHHHHHHCCCEEHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
RPHVRTVLLRGATEAGYDFYTNYDSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIP
CCHHEEHEECCCCCCCCHHEECCCCCCCCCCCCCCHHHEEEECCCCCCCEECCCEEEECC
EQESTDYYHKRPRDSQIAAHISTPQSGKIESRELLQQRFQDLQQQVQSREVLDKPEFWGG
CCCCCCHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
YRLQPDYYEFWQGRPNRLHDRLSYEKIDGQWTLHRLMP
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA