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The map label for this gene is comQ [H]

Identifier: 213158943

GI number: 213158943

Start: 3753035

End: 3755200

Strand: Reverse

Name: comQ [H]

Synonym: AB57_3644

Alternate gene names: 213158943

Gene position: 3755200-3753035 (Counterclockwise)

Preceding gene: 213158944

Following gene: 213158942

Centisome position: 92.71

GC content: 38.64

Gene sequence:

>2166_bases
ATGAATCACGTATTCCGTCAGTTTTCTATGGGGGCTGTAGCTATTGCGATTATGCAGGCTGCATCTGCACAGGTCAGCAT
GACCAATATTGTACCAATGCAAATTGCAGGTCAGGGCACAGAAATTAGAGTCATGTTTAATGGCTTGCCACCACAACCAC
AAGCTTACCAACTTGAAAATCCTTCACGTTTAATCCTTGATTTTGATAAGGTACAGCAAGGTTTAAAACAGTCTAAAATT
AGTGTTGCAACTAATGAGGCAAGTTCTGTAGATGTTACTTCAGATGACCAGCGCTCACGTTTAACTGTAAACCTAAAAGA
TGCTGGAGCATTTACAACACGAGTCGAAGGCAATACTTTCATTTTAAAAATTAATTCTGCTCAAACAAGTAATAAGCCGC
TACCTGTGGTCTCAGCACAACCACAGGGAGTTTCAAATATTGGCTTTCAGCGTGGTAGTCAGGGAGAAGGCCTGGTTGTT
GTAGATCTTTTAGGAAGTAATACGCCTGTAGATGTTCAGCAGCAGGGTAGTAAAGTCGTTATAAGAACAATAGGTACAAA
AATCCCGACACATTTAGCACGTCGCTTAAATGTAAATGATTTTGCAACCCCCGTTTCAAGTATCGATGCTTATAATGATA
AAGGGGTTGGTGTAATAACTATCCAGTCCTCTGGTAGCTATGAATATATGGCCTATCAGGCAGAGAATAAGCTCACGATC
AGTTTGAAACGTCCCCAAGATAAAAATGTTACCTCTTTATATAAAACGCCGAATTATTCAGGAAATAAACTTTCATTAGA
CTTCCAAGATATTGAAGTACGTCGTGTGTTGCAATTACTTGCTGATTTTACAGGCATCAATATGGTAGCTGCTGATAGTG
TACAAGGTAATATCACACTACGTTTAAAAGATGTACCTTGGGATCAGGCTCTTGATATTATTTTAAAAACTAAAAATCTT
GATAAACGCCGTAACGGCAATGTGATTTGGATTGCTCCAGTTGCAGAATTGATTAAGGCGGAAGAAGAAGAAGCGAAAGC
TGTTGCACAAAGTGTCAAACTTGCACCCTTACAGACTGAGTATATTCAACTGAAGTATGCTAAAGCTGGCGATATTATGG
GTCTCATTACACAAGGTTCAAATAATAGTAATGGCTTACAGCATACTTCTGGTGGAGGGACCTCAACTTCAACCAATTTA
AATACTGGAGTTGATAGTCTAGGCAATAATGTGGGTAGTTTGCTTAGCCCGCGTGGCACTATTACTCAAGATGATCGAAC
CAATACTCTTATTATTAACGATACTGCTCAGTCAATTGATCAAATTCGTAAAATGATTGACTTGCTTGATGTGCAAGTTA
AACAGGTTATGGTTGAAGCACGTATTGTGAGAGCCTCTACGTCATTTACCAAAGAACTTGGTGTGAAGTGGGGCATTCTG
TCGCAAGGTATTACCAATAACAACAATTTGCTGGTTGGCGGTAGTGAAACAACTTTATGGAATTTACGCGAACCGAAGAA
AGATGAAACTACAGGTGGGTATAAATATACGATTGAGCGCCCAGATAACTTAAATGTGGATTTAGGAGTTTCTAATCCTG
CAGGAAGTATTGCTTTTGGCTTGATTAGTATGTCTGACTTTATGTTAGATCTTGAATTGTCTGCTTTACAAGCGGATGGT
TATGGTGAGGTTATTTCTACCCCTAAAGTCATGACTGCCGATAAACAAACAGCGAAAGTTGCAACTGGTCAACAAGTTCC
ATATCAATCTACAACTAACTCTGCAGCAGGTTCAACTGCTACAACATCTTTTAAAGATGCTTTGCTGAGTTTAAATGTGA
CACCAAGTATTACACCTGATGGCAAGATTCAAATGAAGTTGGATATTTCTAAGGATTCTGTAGCGGGTGCGGCTCCAAAT
GGAGAGTTGATTTTAAATAAAAATAATATCAACACCAATGTATTGGTAGATAATGGCGAAACTGTCATTTTGGGTGGTGT
TTTTGAGCAAACAACTATGAATTCACAAACCAAAGTTCCTTTCTTTGGTGATATTCCTGTTGTTGGGCGTTTATTTAGAA
AAGATGTAAAGTCTGATGATAAACAAGAGTTGCTGATTTTCGTTACACCACGAATTGTTAATGACACTTTAGCGAGAAAT
CATTAA

Upstream 100 bases:

>100_bases
GACCGAGAACCTTGGTCTTGATTGGGCCTGCACCCTAAAATTTAGGGAATAACAACGAAAAAATATTTTTAAAGATTATT
TAATTGGGGATGGTCAGACA

Downstream 100 bases:

>100_bases
TATATTTTTTAATGAAAGCAATTGAAATAGGTGGCGCCTTGCCAAGCAAAGCGTTTGAAACCCTACCAAATATTTATTTG
GTAGGGCCCATGGGGGCAGG

Product: fimbrial assembly protein PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 721

Protein sequence:

>721_residues
MNHVFRQFSMGAVAIAIMQAASAQVSMTNIVPMQIAGQGTEIRVMFNGLPPQPQAYQLENPSRLILDFDKVQQGLKQSKI
SVATNEASSVDVTSDDQRSRLTVNLKDAGAFTTRVEGNTFILKINSAQTSNKPLPVVSAQPQGVSNIGFQRGSQGEGLVV
VDLLGSNTPVDVQQQGSKVVIRTIGTKIPTHLARRLNVNDFATPVSSIDAYNDKGVGVITIQSSGSYEYMAYQAENKLTI
SLKRPQDKNVTSLYKTPNYSGNKLSLDFQDIEVRRVLQLLADFTGINMVAADSVQGNITLRLKDVPWDQALDIILKTKNL
DKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTEYIQLKYAKAGDIMGLITQGSNNSNGLQHTSGGGTSTSTNL
NTGVDSLGNNVGSLLSPRGTITQDDRTNTLIINDTAQSIDQIRKMIDLLDVQVKQVMVEARIVRASTSFTKELGVKWGIL
SQGITNNNNLLVGGSETTLWNLREPKKDETTGGYKYTIERPDNLNVDLGVSNPAGSIAFGLISMSDFMLDLELSALQADG
YGEVISTPKVMTADKQTAKVATGQQVPYQSTTNSAAGSTATTSFKDALLSLNVTPSITPDGKIQMKLDISKDSVAGAAPN
GELILNKNNINTNVLVDNGETVILGGVFEQTTMNSQTKVPFFGDIPVVGRLFRKDVKSDDKQELLIFVTPRIVNDTLARN
H

Sequences:

>Translated_721_residues
MNHVFRQFSMGAVAIAIMQAASAQVSMTNIVPMQIAGQGTEIRVMFNGLPPQPQAYQLENPSRLILDFDKVQQGLKQSKI
SVATNEASSVDVTSDDQRSRLTVNLKDAGAFTTRVEGNTFILKINSAQTSNKPLPVVSAQPQGVSNIGFQRGSQGEGLVV
VDLLGSNTPVDVQQQGSKVVIRTIGTKIPTHLARRLNVNDFATPVSSIDAYNDKGVGVITIQSSGSYEYMAYQAENKLTI
SLKRPQDKNVTSLYKTPNYSGNKLSLDFQDIEVRRVLQLLADFTGINMVAADSVQGNITLRLKDVPWDQALDIILKTKNL
DKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTEYIQLKYAKAGDIMGLITQGSNNSNGLQHTSGGGTSTSTNL
NTGVDSLGNNVGSLLSPRGTITQDDRTNTLIINDTAQSIDQIRKMIDLLDVQVKQVMVEARIVRASTSFTKELGVKWGIL
SQGITNNNNLLVGGSETTLWNLREPKKDETTGGYKYTIERPDNLNVDLGVSNPAGSIAFGLISMSDFMLDLELSALQADG
YGEVISTPKVMTADKQTAKVATGQQVPYQSTTNSAAGSTATTSFKDALLSLNVTPSITPDGKIQMKLDISKDSVAGAAPN
GELILNKNNINTNVLVDNGETVILGGVFEQTTMNSQTKVPFFGDIPVVGRLFRKDVKSDDKQELLIFVTPRIVNDTLARN
H
>Mature_721_residues
MNHVFRQFSMGAVAIAIMQAASAQVSMTNIVPMQIAGQGTEIRVMFNGLPPQPQAYQLENPSRLILDFDKVQQGLKQSKI
SVATNEASSVDVTSDDQRSRLTVNLKDAGAFTTRVEGNTFILKINSAQTSNKPLPVVSAQPQGVSNIGFQRGSQGEGLVV
VDLLGSNTPVDVQQQGSKVVIRTIGTKIPTHLARRLNVNDFATPVSSIDAYNDKGVGVITIQSSGSYEYMAYQAENKLTI
SLKRPQDKNVTSLYKTPNYSGNKLSLDFQDIEVRRVLQLLADFTGINMVAADSVQGNITLRLKDVPWDQALDIILKTKNL
DKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTEYIQLKYAKAGDIMGLITQGSNNSNGLQHTSGGGTSTSTNL
NTGVDSLGNNVGSLLSPRGTITQDDRTNTLIINDTAQSIDQIRKMIDLLDVQVKQVMVEARIVRASTSFTKELGVKWGIL
SQGITNNNNLLVGGSETTLWNLREPKKDETTGGYKYTIERPDNLNVDLGVSNPAGSIAFGLISMSDFMLDLELSALQADG
YGEVISTPKVMTADKQTAKVATGQQVPYQSTTNSAAGSTATTSFKDALLSLNVTPSITPDGKIQMKLDISKDSVAGAAPN
GELILNKNNINTNVLVDNGETVILGGVFEQTTMNSQTKVPFFGDIPVVGRLFRKDVKSDDKQELLIFVTPRIVNDTLARN
H

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=461, Percent_Identity=30.8026030368764, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI87082242, Length=366, Percent_Identity=27.5956284153005, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 77920; Mature: 77920

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHVFRQFSMGAVAIAIMQAASAQVSMTNIVPMQIAGQGTEIRVMFNGLPPQPQAYQLEN
CCCHHHHHCCCHHHHHHHHHCCCEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCEECCC
PSRLILDFDKVQQGLKQSKISVATNEASSVDVTSDDQRSRLTVNLKDAGAFTTRVEGNTF
CCEEEEEHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCEEEEEEECCCCEEEEECCCEE
ILKINSAQTSNKPLPVVSAQPQGVSNIGFQRGSQGEGLVVVDLLGSNTPVDVQQQGSKVV
EEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCEEE
IRTIGTKIPTHLARRLNVNDFATPVSSIDAYNDKGVGVITIQSSGSYEYMAYQAENKLTI
EEECCCHHHHHHHHHCCCCHHHCCHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCEEEE
SLKRPQDKNVTSLYKTPNYSGNKLSLDFQDIEVRRVLQLLADFTGINMVAADSVQGNITL
EEECCCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEE
RLKDVPWDQALDIILKTKNLDKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTE
EEECCCHHHHEEEEEEECCCCCCCCCCEEEEECHHHHHHCCHHHHHHHHHHHCCCCCEEE
YIQLKYAKAGDIMGLITQGSNNSNGLQHTSGGGTSTSTNLNTGVDSLGNNVGSLLSPRGT
EEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCCCCCCCCCHHHHCCCHHHHCCCCCC
ITQDDRTNTLIINDTAQSIDQIRKMIDLLDVQVKQVMVEARIVRASTSFTKELGVKWGIL
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCEEEEC
SQGITNNNNLLVGGSETTLWNLREPKKDETTGGYKYTIERPDNLNVDLGVSNPAGSIAFG
CCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEE
LISMSDFMLDLELSALQADGYGEVISTPKVMTADKQTAKVATGQQVPYQSTTNSAAGSTA
EHHHHHEEEEEEEEEEECCCCCCHHCCCCEEECCCCHHEEECCCCCCCCCCCCCCCCCCC
TTSFKDALLSLNVTPSITPDGKIQMKLDISKDSVAGAAPNGELILNKNNINTNVLVDNGE
CCHHHHEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEECCC
TVILGGVFEQTTMNSQTKVPFFGDIPVVGRLFRKDVKSDDKQELLIFVTPRIVNDTLARN
EEEEECCCHHCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCC
H
C
>Mature Secondary Structure
MNHVFRQFSMGAVAIAIMQAASAQVSMTNIVPMQIAGQGTEIRVMFNGLPPQPQAYQLEN
CCCHHHHHCCCHHHHHHHHHCCCEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCEECCC
PSRLILDFDKVQQGLKQSKISVATNEASSVDVTSDDQRSRLTVNLKDAGAFTTRVEGNTF
CCEEEEEHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCEEEEEEECCCCEEEEECCCEE
ILKINSAQTSNKPLPVVSAQPQGVSNIGFQRGSQGEGLVVVDLLGSNTPVDVQQQGSKVV
EEEEECCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHCCCEEE
IRTIGTKIPTHLARRLNVNDFATPVSSIDAYNDKGVGVITIQSSGSYEYMAYQAENKLTI
EEECCCHHHHHHHHHCCCCHHHCCHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCEEEE
SLKRPQDKNVTSLYKTPNYSGNKLSLDFQDIEVRRVLQLLADFTGINMVAADSVQGNITL
EEECCCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEE
RLKDVPWDQALDIILKTKNLDKRRNGNVIWIAPVAELIKAEEEEAKAVAQSVKLAPLQTE
EEECCCHHHHEEEEEEECCCCCCCCCCEEEEECHHHHHHCCHHHHHHHHHHHCCCCCEEE
YIQLKYAKAGDIMGLITQGSNNSNGLQHTSGGGTSTSTNLNTGVDSLGNNVGSLLSPRGT
EEEEEEECCCCEEEEEEECCCCCCCCEECCCCCCCCCCCCCCCHHHHCCCHHHHCCCCCC
ITQDDRTNTLIINDTAQSIDQIRKMIDLLDVQVKQVMVEARIVRASTSFTKELGVKWGIL
CCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCEEEEC
SQGITNNNNLLVGGSETTLWNLREPKKDETTGGYKYTIERPDNLNVDLGVSNPAGSIAFG
CCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEE
LISMSDFMLDLELSALQADGYGEVISTPKVMTADKQTAKVATGQQVPYQSTTNSAAGSTA
EHHHHHEEEEEEEEEEECCCCCCHHCCCCEEECCCCHHEEECCCCCCCCCCCCCCCCCCC
TTSFKDALLSLNVTPSITPDGKIQMKLDISKDSVAGAAPNGELILNKNNINTNVLVDNGE
CCHHHHEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEEECCC
TVILGGVFEQTTMNSQTKVPFFGDIPVVGRLFRKDVKSDDKQELLIFVTPRIVNDTLARN
EEEEECCCHHCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]