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The map label for this gene is aroK [H]

Identifier: 213158942

GI number: 213158942

Start: 3752454

End: 3753023

Strand: Reverse

Name: aroK [H]

Synonym: AB57_3643

Alternate gene names: 213158942

Gene position: 3753023-3752454 (Counterclockwise)

Preceding gene: 213158943

Following gene: 213158941

Centisome position: 92.66

GC content: 40.88

Gene sequence:

>570_bases
ATGAAAGCAATTGAAATAGGTGGCGCCTTGCCAAGCAAAGCGTTTGAAACCCTACCAAATATTTATTTGGTAGGGCCCAT
GGGGGCAGGAAAAACAACCGTTGGACGTCATTTAGCAGAACTATTAGGGCGTGAATTTTTAGATAGTGATCATGAAATTG
AGCGCAAGACAGGGGCCACTATTCCCTGGATTTTTGAAAAAGAAGGAGAAGTCGGCTTCCGTACGCGTGAAACTGTCGTT
TTAAATGAGCTTACTTCACGTAAGGCATTAGTGCTTGCCACAGGTGGCGGTGCTATTACTCAGGCGCCTAATCGGGAGTT
TTTAAAGCAACGTGGAATCGTTGTTTATCTATATACTCCTGTCGAATTACAACTACAAAGAACCTATCGCGATAAAAATA
GACCTTTATTACAAGTTGAAAATCCTGAACAAAAATTGCGGGATTTATTAAAGATCAGAGATCCTCTGTATCGTGAAGTT
GCACACTATACGATTGAAACGAATCAAGGTGCTGCACGTGATCTTGCCCAAAAGATTTTGCAACTTATTCTATCGAACAA
GTTAAAATAG

Upstream 100 bases:

>100_bases
GAAAAGATGTAAAGTCTGATGATAAACAAGAGTTGCTGATTTTCGTTACACCACGAATTGTTAATGACACTTTAGCGAGA
AATCATTAATATATTTTTTA

Downstream 100 bases:

>100_bases
ACGAACTGACTAGTGGTTTTATAAATTCATGCAAACTTTACATGTTGAATTAGGCGAACGCCGTTATCCTATTTTCATTG
GTAGCCAACTTGACCCGAAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKAIEIGGALPSKAFETLPNIYLVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTGATIPWIFEKEGEVGFRTRETVV
LNELTSRKALVLATGGGAITQAPNREFLKQRGIVVYLYTPVELQLQRTYRDKNRPLLQVENPEQKLRDLLKIRDPLYREV
AHYTIETNQGAARDLAQKILQLILSNKLK

Sequences:

>Translated_189_residues
MKAIEIGGALPSKAFETLPNIYLVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTGATIPWIFEKEGEVGFRTRETVV
LNELTSRKALVLATGGGAITQAPNREFLKQRGIVVYLYTPVELQLQRTYRDKNRPLLQVENPEQKLRDLLKIRDPLYREV
AHYTIETNQGAARDLAQKILQLILSNKLK
>Mature_189_residues
MKAIEIGGALPSKAFETLPNIYLVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTGATIPWIFEKEGEVGFRTRETVV
LNELTSRKALVLATGGGAITQAPNREFLKQRGIVVYLYTPVELQLQRTYRDKNRPLLQVENPEQKLRDLLKIRDPLYREV
AHYTIETNQGAARDLAQKILQLILSNKLK

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=176, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=53.5714285714286, Blast_Score=182, Evalue=1e-47,
Organism=Escherichia coli, GI1786587, Length=153, Percent_Identity=42.483660130719, Blast_Score=115, Evalue=1e-27,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21319; Mature: 21319

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEIGGALPSKAFETLPNIYLVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTGAT
CCEEECCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
IPWIFEKEGEVGFRTRETVVLNELTSRKALVLATGGGAITQAPNREFLKQRGIVVYLYTP
CCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEECC
VELQLQRTYRDKNRPLLQVENPEQKLRDLLKIRDPLYREVAHYTIETNQGAARDLAQKIL
CEEEHHHHHHCCCCCEEEECCHHHHHHHHHHHHCHHHHHHHHEEEECCCCHHHHHHHHHH
QLILSNKLK
HHHHHCCCC
>Mature Secondary Structure
MKAIEIGGALPSKAFETLPNIYLVGPMGAGKTTVGRHLAELLGREFLDSDHEIERKTGAT
CCEEECCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
IPWIFEKEGEVGFRTRETVVLNELTSRKALVLATGGGAITQAPNREFLKQRGIVVYLYTP
CCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEECC
VELQLQRTYRDKNRPLLQVENPEQKLRDLLKIRDPLYREVAHYTIETNQGAARDLAQKIL
CEEEHHHHHHCCCCCEEEECCHHHHHHHHHHHHCHHHHHHHHEEEECCCCHHHHHHHHHH
QLILSNKLK
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA