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The map label for this gene is astC [H]

Identifier: 213158888

GI number: 213158888

Start: 3693913

End: 3695127

Strand: Reverse

Name: astC [H]

Synonym: AB57_3587

Alternate gene names: 213158888

Gene position: 3695127-3693913 (Counterclockwise)

Preceding gene: 213158889

Following gene: 213158887

Centisome position: 91.23

GC content: 41.81

Gene sequence:

>1215_bases
ATGGAACAGCCAATTTCTGTAACTCGAAGCAACTTTAATGACTGGATGGTTCCAGTATTTGCACCGGCAAATTTCATTCC
GGTACGTGGTGAAGGTTCACGTATCTGGGATCAAGAAAATAAAGAATATATCGATTTTGCAGGCGGGATTGCAGTAAATG
CATTAGGTCATGCGCATCCAGTGGCAGTCAATGCGTTAACAGAACAAGCAAAAAAACTTTGGCACGTTGGTAATGGCTAT
ACCAATGAACCAGTACTACGCCTTGCTAAACAACTCACTGAAAATACATTTGCCGATAAAGTATTCTTCTGTAACTCAGG
TGCAGAAGCGAATGAGGCAGCTTTAAAACTTGCGCGTAAAGTTGGACTCGACAGCGGTGTTGCAGGTAAAAGTGGCATTG
TGGCATTTAACAATGCTTTCCACGGCCGTACCTTATTTACCGTTTCAGCAGGCGGCCAGCCAAAATATTCACAAGACTTT
GCACCACTTCCAAACGGTATTAGCCATGTTGCTTATAATGATTTAGAAGCAGCTAAAGCAGTCATAAATGAACAAACTTG
TGCAGTAATTGTAGAGCCTGTACAAGGTGAAGGCGGAGTTATTCCGGCTGATATCGAATTTTTAAAAGGTTTACGTGAAC
TGTGTGATCAGTTCGGTGCCTTACTTATTTTTGATGAAGTACAAACTGGTGTGGGCCGTACAGGTGCACTTTATGCCTAC
ATGAACTACGGTGTGATTCCGGATGTACTTACGACTGCAAAAGCATTGGGCGGTGGTTTCCCGGTCGGTGCAATGTTAAC
AACTGATAAGTTCGCACCGCATTTTTCTGTAGGTACACATGGTACAACTTACGGTGGTAACCCGTTAGCAAGTGCAGTTG
CAGGTGCGGTTTTTGAGTTTATTAATACACCAGAAGTACTTGAAGGTGTGAAACACCGTCATCAATATTTCCTTGATGCA
TTAAATACTTTAAATGCTGAATATCAAGTATTTGATGAAATTCGTGGTCAAGGTTTATTGATTGGCTGTGTACTAAAAGC
TGAATATGCAGGTAAAGCGAAAGACATTACCACATGGGCAGGCGAAGAAGGATTACTCGCTTTAATCGCAGGACCTAACG
TGGTTCGTTTCACTCCTTCTCTAATTATTCCTGAACAAGATATTGATGAAGGGATTGCTCGTTTAAAAAGAGCTTTGGCA
AAGTTGGCTAAATAA

Upstream 100 bases:

>100_bases
AAGGATGTTATAGGGTTATTTGTTCGGTCCCTTTTTCTAAATGAATTAAATTAAAGACAGTAAGACAGATTAAATAAATT
AAATAGATACTGAGGTAAGC

Downstream 100 bases:

>100_bases
AAAAAAGGAAAGCTAGCCATGATGATTGTCCGTCATGCCGAGTTTCGAGACCTTGAAGATATTTATAAATTAGCAGGTAA
GTCAGGTGTTGGCCTGACTT

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEQPISVTRSNFNDWMVPVFAPANFIPVRGEGSRIWDQENKEYIDFAGGIAVNALGHAHPVAVNALTEQAKKLWHVGNGY
TNEPVLRLAKQLTENTFADKVFFCNSGAEANEAALKLARKVGLDSGVAGKSGIVAFNNAFHGRTLFTVSAGGQPKYSQDF
APLPNGISHVAYNDLEAAKAVINEQTCAVIVEPVQGEGGVIPADIEFLKGLRELCDQFGALLIFDEVQTGVGRTGALYAY
MNYGVIPDVLTTAKALGGGFPVGAMLTTDKFAPHFSVGTHGTTYGGNPLASAVAGAVFEFINTPEVLEGVKHRHQYFLDA
LNTLNAEYQVFDEIRGQGLLIGCVLKAEYAGKAKDITTWAGEEGLLALIAGPNVVRFTPSLIIPEQDIDEGIARLKRALA
KLAK

Sequences:

>Translated_404_residues
MEQPISVTRSNFNDWMVPVFAPANFIPVRGEGSRIWDQENKEYIDFAGGIAVNALGHAHPVAVNALTEQAKKLWHVGNGY
TNEPVLRLAKQLTENTFADKVFFCNSGAEANEAALKLARKVGLDSGVAGKSGIVAFNNAFHGRTLFTVSAGGQPKYSQDF
APLPNGISHVAYNDLEAAKAVINEQTCAVIVEPVQGEGGVIPADIEFLKGLRELCDQFGALLIFDEVQTGVGRTGALYAY
MNYGVIPDVLTTAKALGGGFPVGAMLTTDKFAPHFSVGTHGTTYGGNPLASAVAGAVFEFINTPEVLEGVKHRHQYFLDA
LNTLNAEYQVFDEIRGQGLLIGCVLKAEYAGKAKDITTWAGEEGLLALIAGPNVVRFTPSLIIPEQDIDEGIARLKRALA
KLAK
>Mature_404_residues
MEQPISVTRSNFNDWMVPVFAPANFIPVRGEGSRIWDQENKEYIDFAGGIAVNALGHAHPVAVNALTEQAKKLWHVGNGY
TNEPVLRLAKQLTENTFADKVFFCNSGAEANEAALKLARKVGLDSGVAGKSGIVAFNNAFHGRTLFTVSAGGQPKYSQDF
APLPNGISHVAYNDLEAAKAVINEQTCAVIVEPVQGEGGVIPADIEFLKGLRELCDQFGALLIFDEVQTGVGRTGALYAY
MNYGVIPDVLTTAKALGGGFPVGAMLTTDKFAPHFSVGTHGTTYGGNPLASAVAGAVFEFINTPEVLEGVKHRHQYFLDA
LNTLNAEYQVFDEIRGQGLLIGCVLKAEYAGKAKDITTWAGEEGLLALIAGPNVVRFTPSLIIPEQDIDEGIARLKRALA
KLAK

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=375, Percent_Identity=35.7333333333333, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.7892976588629, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=27.2941176470588, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=28.6052009456265, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=29.1237113402062, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=27.8959810874704, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=413, Percent_Identity=25.90799031477, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI188536080, Length=417, Percent_Identity=23.2613908872902, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI38679950, Length=417, Percent_Identity=23.2613908872902, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI38679946, Length=417, Percent_Identity=23.2613908872902, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=70.3517587939699, Blast_Score=581, Evalue=1e-167,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=60.2015113350126, Blast_Score=513, Evalue=1e-146,
Organism=Escherichia coli, GI1789016, Length=403, Percent_Identity=34.2431761786601, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI145693181, Length=333, Percent_Identity=38.1381381381381, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=34.2364532019704, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=35.9872611464968, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786991, Length=288, Percent_Identity=32.2916666666667, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=394, Percent_Identity=34.5177664974619, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=30.1401869158879, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25144274, Length=274, Percent_Identity=35.036496350365, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=28.4382284382284, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=31.7919075144509, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=437, Percent_Identity=25.1716247139588, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=40.2035623409669, Blast_Score=277, Evalue=3e-75,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=33.0049261083744, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324386, Length=342, Percent_Identity=28.3625730994152, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=424, Percent_Identity=25.2358490566038, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21357415, Length=387, Percent_Identity=35.4005167958656, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI161085790, Length=452, Percent_Identity=29.4247787610619, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574759, Length=440, Percent_Identity=30, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=28.436018957346, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281366494, Length=301, Percent_Identity=27.5747508305648, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667139, Length=301, Percent_Identity=27.5747508305648, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667143, Length=301, Percent_Identity=27.5747508305648, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43235; Mature: 43235

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPISVTRSNFNDWMVPVFAPANFIPVRGEGSRIWDQENKEYIDFAGGIAVNALGHAHP
CCCCCCHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCEEEECCCEEEECCCCCCC
VAVNALTEQAKKLWHVGNGYTNEPVLRLAKQLTENTFADKVFFCNSGAEANEAALKLARK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
VGLDSGVAGKSGIVAFNNAFHGRTLFTVSAGGQPKYSQDFAPLPNGISHVAYNDLEAAKA
HCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VINEQTCAVIVEPVQGEGGVIPADIEFLKGLRELCDQFGALLIFDEVQTGVGRTGALYAY
HHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCEEEEE
MNYGVIPDVLTTAKALGGGFPVGAMLTTDKFAPHFSVGTHGTTYGGNPLASAVAGAVFEF
ECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
INTPEVLEGVKHRHQYFLDALNTLNAEYQVFDEIRGQGLLIGCVLKAEYAGKAKDITTWA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEHHHCCCCCCCEEEC
GEEGLLALIAGPNVVRFTPSLIIPEQDIDEGIARLKRALAKLAK
CCCCCEEEEECCCEEEECCCEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQPISVTRSNFNDWMVPVFAPANFIPVRGEGSRIWDQENKEYIDFAGGIAVNALGHAHP
CCCCCCHHHCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCEEEECCCEEEECCCCCCC
VAVNALTEQAKKLWHVGNGYTNEPVLRLAKQLTENTFADKVFFCNSGAEANEAALKLARK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
VGLDSGVAGKSGIVAFNNAFHGRTLFTVSAGGQPKYSQDFAPLPNGISHVAYNDLEAAKA
HCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VINEQTCAVIVEPVQGEGGVIPADIEFLKGLRELCDQFGALLIFDEVQTGVGRTGALYAY
HHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCEEEEE
MNYGVIPDVLTTAKALGGGFPVGAMLTTDKFAPHFSVGTHGTTYGGNPLASAVAGAVFEF
ECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
INTPEVLEGVKHRHQYFLDALNTLNAEYQVFDEIRGQGLLIGCVLKAEYAGKAKDITTWA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEHHHCCCCCCCEEEC
GEEGLLALIAGPNVVRFTPSLIIPEQDIDEGIARLKRALAKLAK
CCCCCEEEEECCCEEEECCCEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA