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The map label for this gene is corA [H]

Identifier: 213158853

GI number: 213158853

Start: 3654135

End: 3655148

Strand: Direct

Name: corA [H]

Synonym: AB57_3548

Alternate gene names: 213158853

Gene position: 3654135-3655148 (Clockwise)

Preceding gene: 213158850

Following gene: 213158862

Centisome position: 90.21

GC content: 39.55

Gene sequence:

>1014_bases
ATGCTTGAAGCCTTTTATGCCACAGAACGCGGAAGTCTGGAAGATGCCACCATCAATGGTGGATTTGATCTACATCCCGA
ATTAGTATGGCTTGATCTTATTGCACCCTCTCAAGAAGAACAACAATGGGTCTTAGATGCTTACAATCAGAACTTACCTA
CACTAAAGTCGTTAGAAGACATTTCATCTTCTGCTCGATTCTACCGTGATGATGACGGTATTTTGCATATCAGCACCTAT
TTTTTAACGAAAAATAAAAATTATCAGGTTGATGGGGATGCCGAAGATTCTTCCCATATGCTTGCCATGGTGCAGACTGT
TGCATTCATCTTACATAAAGATCGCTTATTTACTTTACGTGGTGAAAAGTTAGTTGCCTTTCGTGCTTTTCGTGCTCGAG
CTCGTCGTAATGACTACGAAATGGATTATAAAGATCCAACATGGATTTTATTGGGCTTACTTGAAGCAAAGCTAGATGAG
CTTGCGGATATCTTGGAAGATATCCACAAGGATCTAGAAAAATACTCAACCGAGGTTCTCAATAACCATCAACGTGAACA
GATTTTAGATCTTGATGACATGATTACCCGTCTGGCACAACAAGAAGACATGCTTGGGAAAGCACAGCTCTGTTTAATTG
ATTTGCGCCGTGTTTTAACGTTTTTGTCTCGTCCACGTGCTTTAGGCAGTCATATCTACGATGCAGATATTCGAGAACTT
AGTGAAGATGTTCGCTCGCTTGTCGAACATGACGCTTTCTTATTCCAAAAAGTACGATTCTTGCTTGATACAACGTCAGG
ATTTATTAACACTGAACAAAACGATACGATCCGTCGATTCTCGATATTACCAAGTATGTTGGCACCACCTATGTTAATCG
CCAGTATCTATGGTATGAACACGGATGTACTTCCTTTCGCACACGGTACAACCAGCTTTATTATCGTTTTATTAATTATT
ATTGGTTTCTTTATTGGGCCTATCATTTATTTCCGCTGGAAAAAATGGATTTAA

Upstream 100 bases:

>100_bases
TTTTTTTTGCAAAATAGCGTATTGGCAAGTGTTTTTCGGCAAATCCTTGTCTAAAATACACCCATCAATTTCCATCAGAC
TGCGTAAGGAAAAAAGACAC

Downstream 100 bases:

>100_bases
AGAGATTACCCCCGCAAATTTTGTATATAAAAAAGCACCTAAATTTAGGTGCTTTTTTATCTTTGCTCATCAAACCAAAT
GTAGGTCTTCTTGCAAATGG

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLEAFYATERGSLEDATINGGFDLHPELVWLDLIAPSQEEQQWVLDAYNQNLPTLKSLEDISSSARFYRDDDGILHISTY
FLTKNKNYQVDGDAEDSSHMLAMVQTVAFILHKDRLFTLRGEKLVAFRAFRARARRNDYEMDYKDPTWILLGLLEAKLDE
LADILEDIHKDLEKYSTEVLNNHQREQILDLDDMITRLAQQEDMLGKAQLCLIDLRRVLTFLSRPRALGSHIYDADIREL
SEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLIASIYGMNTDVLPFAHGTTSFIIVLLII
IGFFIGPIIYFRWKKWI

Sequences:

>Translated_337_residues
MLEAFYATERGSLEDATINGGFDLHPELVWLDLIAPSQEEQQWVLDAYNQNLPTLKSLEDISSSARFYRDDDGILHISTY
FLTKNKNYQVDGDAEDSSHMLAMVQTVAFILHKDRLFTLRGEKLVAFRAFRARARRNDYEMDYKDPTWILLGLLEAKLDE
LADILEDIHKDLEKYSTEVLNNHQREQILDLDDMITRLAQQEDMLGKAQLCLIDLRRVLTFLSRPRALGSHIYDADIREL
SEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLIASIYGMNTDVLPFAHGTTSFIIVLLII
IGFFIGPIIYFRWKKWI
>Mature_337_residues
MLEAFYATERGSLEDATINGGFDLHPELVWLDLIAPSQEEQQWVLDAYNQNLPTLKSLEDISSSARFYRDDDGILHISTY
FLTKNKNYQVDGDAEDSSHMLAMVQTVAFILHKDRLFTLRGEKLVAFRAFRARARRNDYEMDYKDPTWILLGLLEAKLDE
LADILEDIHKDLEKYSTEVLNNHQREQILDLDDMITRLAQQEDMLGKAQLCLIDLRRVLTFLSRPRALGSHIYDADIREL
SEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLIASIYGMNTDVLPFAHGTTSFIIVLLII
IGFFIGPIIYFRWKKWI

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=312, Percent_Identity=40.0641025641026, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 39016; Mature: 39016

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEAFYATERGSLEDATINGGFDLHPELVWLDLIAPSQEEQQWVLDAYNQNLPTLKSLED
CCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHH
ISSSARFYRDDDGILHISTYFLTKNKNYQVDGDAEDSSHMLAMVQTVAFILHKDRLFTLR
HHHHHCEEECCCCEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEC
GEKLVAFRAFRARARRNDYEMDYKDPTWILLGLLEAKLDELADILEDIHKDLEKYSTEVL
CCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNHQREQILDLDDMITRLAQQEDMLGKAQLCLIDLRRVLTFLSRPRALGSHIYDADIREL
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLIASIYGMN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
TDVLPFAHGTTSFIIVLLIIIGFFIGPIIYFRWKKWI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEAFYATERGSLEDATINGGFDLHPELVWLDLIAPSQEEQQWVLDAYNQNLPTLKSLED
CCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHH
ISSSARFYRDDDGILHISTYFLTKNKNYQVDGDAEDSSHMLAMVQTVAFILHKDRLFTLR
HHHHHCEEECCCCEEEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEC
GEKLVAFRAFRARARRNDYEMDYKDPTWILLGLLEAKLDELADILEDIHKDLEKYSTEVL
CCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNHQREQILDLDDMITRLAQQEDMLGKAQLCLIDLRRVLTFLSRPRALGSHIYDADIREL
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SEDVRSLVEHDAFLFQKVRFLLDTTSGFINTEQNDTIRRFSILPSMLAPPMLIASIYGMN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
TDVLPFAHGTTSFIIVLLIIIGFFIGPIIYFRWKKWI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA