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The map label for this gene is ribA [H]

Identifier: 213158862

GI number: 213158862

Start: 3664280

End: 3664882

Strand: Direct

Name: ribA [H]

Synonym: AB57_3559

Alternate gene names: 213158862

Gene position: 3664280-3664882 (Clockwise)

Preceding gene: 213158853

Following gene: 213158863

Centisome position: 90.46

GC content: 40.46

Gene sequence:

>603_bases
GTGCCTATAGAGTTCATTGCAACATCAAAACTCCCGACCGCTTTTGGTGAATTCAATATTTCTGTGTTTCAAGATCCCGT
AACAGGTGAAGAACATGTGGCACTTTCCAAAGGGTTAGAAAATCCGCCAACGGGTCCTGTTTTGGTCCGCGTACATTCTG
AATGCTTAACGGGTGATGCGTTTGCATCATTGAAATGTGACTGTGGCCCACAACTACAAGCCACTCAGAAACTCATCAAT
GAAGCAGGACAAGGTGTAATTTTATACTTACGCCAAGAAGGACGCGGTATTGGTTTAACCAATAAAATTCGTGCTTATGC
TCTGCAAGATCAGGGGCACGATACAGTAGATGCCAATTTACTACTGAATTTACCCGCCGATGCACGTCGTTACGATATGT
GCAGTATTATGCTCGACCACTTAAAAGTGAAAGAAGTTAAATTAATTACCAATAATCCTTTGAAAATTCAGGCACTCAAA
GATCAAGGTATTAATGTCGTAGACCGTGTACCTTTAACTGTCGGCCGTAACCCTTTTAATGAACATTATTTAAAAACCAA
ACGTGAAAGAATGGATCACCTTTACCAAAAAGATGATTTTTGA

Upstream 100 bases:

>100_bases
AAAAGAAAACCTTAGTGTGCAAAATGATTATGACAATTCGACCAATCTCCCAGCATTACGCTATACTTTAACCGTTTTCG
GTTAAAAGATGAGTTAATCT

Downstream 100 bases:

>100_bases
TTTCAAGTCCAAAATTTAAAAACTATATTTAAGGGATTTTTTCAGGAATTAGAAAAAATCCCTTACTTTTTTTATGGATT
TATGTTTTGATGTATCTAAT

Product: GTP cyclohydrolase II

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLIN
EAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALK
DQGINVVDRVPLTVGRNPFNEHYLKTKRERMDHLYQKDDF

Sequences:

>Translated_200_residues
MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLIN
EAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALK
DQGINVVDRVPLTVGRNPFNEHYLKTKRERMDHLYQKDDF
>Mature_199_residues
PIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDAFASLKCDCGPQLQATQKLINE
AGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANLLLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKD
QGINVVDRVPLTVGRNPFNEHYLKTKRERMDHLYQKDDF

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=197, Percent_Identity=57.3604060913706, Blast_Score=225, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6319438, Length=195, Percent_Identity=41.5384615384615, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 22323; Mature: 22192

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDA
CCCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEEEEECCHHCCCC
FASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANL
CEEEECCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCEECCEE
LLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFN
EEECCCCCHHHHHHHHHHHHHCEEEEEEEECCCEEEEEECCCCCCEECCCCEEECCCCCH
EHYLKTKRERMDHLYQKDDF
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIEFIATSKLPTAFGEFNISVFQDPVTGEEHVALSKGLENPPTGPVLVRVHSECLTGDA
CCEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEEEEECCHHCCCC
FASLKCDCGPQLQATQKLINEAGQGVILYLRQEGRGIGLTNKIRAYALQDQGHDTVDANL
CEEEECCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCEECCEE
LLNLPADARRYDMCSIMLDHLKVKEVKLITNNPLKIQALKDQGINVVDRVPLTVGRNPFN
EEECCCCCHHHHHHHHHHHHHCEEEEEEEECCCEEEEEECCCCCCEECCCCEEECCCCCH
EHYLKTKRERMDHLYQKDDF
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA