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The map label for this gene is rnr [H]

Identifier: 213158798

GI number: 213158798

Start: 3608286

End: 3610703

Strand: Direct

Name: rnr [H]

Synonym: AB57_3493

Alternate gene names: 213158798

Gene position: 3608286-3610703 (Clockwise)

Preceding gene: 213158796

Following gene: 213158799

Centisome position: 89.08

GC content: 40.24

Gene sequence:

>2418_bases
ATGACAAAAAACTGGGTTGACCCCGAAGCAAAAGCCGAAGCTGAACGTTATGACAATCCTATTCCAAGCCGTACTCTTAT
TTTAGATACGTTGGAACAATTGCAAACACCGCAATCTCATGCAGAACTTGTTGACCATTTTCATATTCAAGATCAGAAAA
GTATTGAAGCCTTAAGTCATCGCTTAAGTGCTATGGTTCGTGATGGCCAACTTATGAAGGATGGTTTTAAGTTTCAGTTG
GTGGCAGACCAACCTACCTATGAAGCAACTGTCTATATTAATAGTAAAGGTTTGGGTACAGCACATATTGATGGTCAAGA
TGATTTGTTATTACCTGAGCGTGAGTTACGTTTAGTCTTTAATGGTGATCGGGTCCGTGTTCGGCAGACATCGGTAGATC
GCAAAGGTAAACCGTGGGGTTTCATTACCGAAGTTATACAGCATCGTGTAAAACAGTTAATTGGTAAATTGTCGGTACAT
GACGGCGAATATTTTATTCAGCCCAACAATCCAAATCAGCATCAACCTATCCCTCTAGAAAAAGAATTGGTTGAACATGC
TAAAGCAAATGTCGGCGATATGCTTCGTGTTGCTATAGACACTTACCCAACCCGGGAAGAATTTGCAACGGCACATATTA
TTCAGTCTATGGCAGATAAAGCCGATACTGAAATTATTATCCCGCAGACCATTTTAGAGTTTGGTTTGCCTTACGAATTT
CCAGATGAAGTTATAAAAGAAGCTGAAAGTTTCAAAGAACCTGCTGAACAAGATCGCGAAGGTCGAGTTGATTTAAGAGA
CTTGGCACTTGTCACAATCGATGGTGAAGATGCGCGAGATTTCGATGATGCAGTATATGCGGAAAAACGTCCTGGTGGTG
GTTACCGAGTTGTCGTTGCAATTGCCGATGTGAGCCATTATGTACGTTTAGATTCGGCACTAAATGAAGAAGCTGAAGAG
CGCGGCACTTCGGTTTATTTCCCACATTTTGTTTTACCAATGCTACCAGAAGCATTATCAAATGGATTGTGCTCACTTAA
CCCACACGTAGATCGTCTATGCATGGTCTGTGACCTAAAACTTTCTCGTACGGGTCGTGTTACAGGTTATGAATTTTATC
CGGCAGTCATGCATTCAAAAGCACGTTTGACCTATACACAAGTAGGACAATATTTTGAAGGTGCAACTGATGCAATTCCA
AAAGATCGTGATATTCATAAATCGCTAAATACACTTTTCCAGCTTTACCAGATTTTGAAAAACTTACGTGTTGATCGTCA
TGCAATGGAGTTTGAAACCATTGAAACTTATATGACCTTTGACGAGTTAGGTGGAATTAAAGAAATTTTACCTCGTACAC
GTAATGATGCTCATAAGCTTATTGAAGAGTGTATGTTGCTTGCCAATGTAGCAGCAGCAGAATATGCCTTAGAACATGAT
ATTCCGATGTTGTATCGTGTACATGAGGCACCTGAATTCTCACGTATTCAAAAAGTAAAAGATTTTGTAAAACTATTGGG
TTTACCTTTCCCTGACCAACCAACTCAGGCAGATTATCAAAAAGTTATTGAGGCAACTAAAGACCGTATTGATGCGCCAA
GCATTCACGCCGTGTTATTACGCTCAATGATGCAAGCTTACTATGGTGCCAAAAATGCAGGTCACTATGGTCTAGCTTAT
GAAGCTTATACACATTTCACTTCACCAATTCGCCGCTACCCGGACTTATTGTTACATCGTGCAATTAAAGCTCATCTAAA
ACAAAAGCCTTACCCACTTTCCGGTGCAGCTTTAGATGATGCAGGTGAACATTTCTCTCAAACAGAACGCCGTGCCGATG
AAGCATCCCGCAGCGTAACGACTTGGTTGAAATGTCACTATATGCAACAACATTTAGGTGATGAGTTCATTGGTATTGTG
AGTGCGGTAACTGAATTTGGCCTATTTGTTACTCTTAAAGATCTTTATGTTGATGGCATGATTCACATTAGCCAACTTGG
CGATGATTTCTTTATTTACGATCAAGCTAGTCAAAACCTCATTGGACAAAATCGTGGTCAAGTCTTCGGTTTAGGCGATG
AAGTTAAAATTCAAGTTGCTGGTGTAAATCTAGAAGAGCGTAAAATCGATTTCCAACTCATTAAACAAGTTACTCATGCT
GGACGTGTAGTTCGTAGTCGCGCTCCACGCACAACCAAAACAAGCACCCAAGCAACAGAAGAAGTTTTTGGTAAACCGTC
TGTATCAACTGATGGTGAAAAACCTGTCCGTAAAAAGAAGGAAAAAGGCAAACCAAGCTCATATAGTAAAAAGTCTGGTA
AGAAAACCTCTACAAAAGCAGAGGCTAAACCAGAAAAAGTAAAGAAAAAAGCGAAACCTAAAAAGAAAAAGTCAAACGCC
AAGTCTAAGGCTGACTAA

Upstream 100 bases:

>100_bases
CAACACAGTAGTGCATAACACATTATTGCAAACCTGAACGTGCAGTTCTGGTCTGCATGTCTTATGCTAAACCTATCTGC
CAAGCATGAAACCAAACGAC

Downstream 100 bases:

>100_bases
TTCATAGGTATTTGCATTAATTATGATTAAGCTCCCAAAATGGGGGCTTAATGTTTTTAAAACGTTTATTTTTTAAATTA
AGCTTGATTTCCTACCTAAC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 805; Mature: 804

Protein sequence:

>805_residues
MTKNWVDPEAKAEAERYDNPIPSRTLILDTLEQLQTPQSHAELVDHFHIQDQKSIEALSHRLSAMVRDGQLMKDGFKFQL
VADQPTYEATVYINSKGLGTAHIDGQDDLLLPERELRLVFNGDRVRVRQTSVDRKGKPWGFITEVIQHRVKQLIGKLSVH
DGEYFIQPNNPNQHQPIPLEKELVEHAKANVGDMLRVAIDTYPTREEFATAHIIQSMADKADTEIIIPQTILEFGLPYEF
PDEVIKEAESFKEPAEQDREGRVDLRDLALVTIDGEDARDFDDAVYAEKRPGGGYRVVVAIADVSHYVRLDSALNEEAEE
RGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLKLSRTGRVTGYEFYPAVMHSKARLTYTQVGQYFEGATDAIP
KDRDIHKSLNTLFQLYQILKNLRVDRHAMEFETIETYMTFDELGGIKEILPRTRNDAHKLIEECMLLANVAAAEYALEHD
IPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQKVIEATKDRIDAPSIHAVLLRSMMQAYYGAKNAGHYGLAY
EAYTHFTSPIRRYPDLLLHRAIKAHLKQKPYPLSGAALDDAGEHFSQTERRADEASRSVTTWLKCHYMQQHLGDEFIGIV
SAVTEFGLFVTLKDLYVDGMIHISQLGDDFFIYDQASQNLIGQNRGQVFGLGDEVKIQVAGVNLEERKIDFQLIKQVTHA
GRVVRSRAPRTTKTSTQATEEVFGKPSVSTDGEKPVRKKKEKGKPSSYSKKSGKKTSTKAEAKPEKVKKKAKPKKKKSNA
KSKAD

Sequences:

>Translated_805_residues
MTKNWVDPEAKAEAERYDNPIPSRTLILDTLEQLQTPQSHAELVDHFHIQDQKSIEALSHRLSAMVRDGQLMKDGFKFQL
VADQPTYEATVYINSKGLGTAHIDGQDDLLLPERELRLVFNGDRVRVRQTSVDRKGKPWGFITEVIQHRVKQLIGKLSVH
DGEYFIQPNNPNQHQPIPLEKELVEHAKANVGDMLRVAIDTYPTREEFATAHIIQSMADKADTEIIIPQTILEFGLPYEF
PDEVIKEAESFKEPAEQDREGRVDLRDLALVTIDGEDARDFDDAVYAEKRPGGGYRVVVAIADVSHYVRLDSALNEEAEE
RGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLKLSRTGRVTGYEFYPAVMHSKARLTYTQVGQYFEGATDAIP
KDRDIHKSLNTLFQLYQILKNLRVDRHAMEFETIETYMTFDELGGIKEILPRTRNDAHKLIEECMLLANVAAAEYALEHD
IPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQKVIEATKDRIDAPSIHAVLLRSMMQAYYGAKNAGHYGLAY
EAYTHFTSPIRRYPDLLLHRAIKAHLKQKPYPLSGAALDDAGEHFSQTERRADEASRSVTTWLKCHYMQQHLGDEFIGIV
SAVTEFGLFVTLKDLYVDGMIHISQLGDDFFIYDQASQNLIGQNRGQVFGLGDEVKIQVAGVNLEERKIDFQLIKQVTHA
GRVVRSRAPRTTKTSTQATEEVFGKPSVSTDGEKPVRKKKEKGKPSSYSKKSGKKTSTKAEAKPEKVKKKAKPKKKKSNA
KSKAD
>Mature_804_residues
TKNWVDPEAKAEAERYDNPIPSRTLILDTLEQLQTPQSHAELVDHFHIQDQKSIEALSHRLSAMVRDGQLMKDGFKFQLV
ADQPTYEATVYINSKGLGTAHIDGQDDLLLPERELRLVFNGDRVRVRQTSVDRKGKPWGFITEVIQHRVKQLIGKLSVHD
GEYFIQPNNPNQHQPIPLEKELVEHAKANVGDMLRVAIDTYPTREEFATAHIIQSMADKADTEIIIPQTILEFGLPYEFP
DEVIKEAESFKEPAEQDREGRVDLRDLALVTIDGEDARDFDDAVYAEKRPGGGYRVVVAIADVSHYVRLDSALNEEAEER
GTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLKLSRTGRVTGYEFYPAVMHSKARLTYTQVGQYFEGATDAIPK
DRDIHKSLNTLFQLYQILKNLRVDRHAMEFETIETYMTFDELGGIKEILPRTRNDAHKLIEECMLLANVAAAEYALEHDI
PMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQKVIEATKDRIDAPSIHAVLLRSMMQAYYGAKNAGHYGLAYE
AYTHFTSPIRRYPDLLLHRAIKAHLKQKPYPLSGAALDDAGEHFSQTERRADEASRSVTTWLKCHYMQQHLGDEFIGIVS
AVTEFGLFVTLKDLYVDGMIHISQLGDDFFIYDQASQNLIGQNRGQVFGLGDEVKIQVAGVNLEERKIDFQLIKQVTHAG
RVVRSRAPRTTKTSTQATEEVFGKPSVSTDGEKPVRKKKEKGKPSSYSKKSGKKTSTKAEAKPEKVKKKAKPKKKKSNAK
SKAD

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=632, Percent_Identity=28.4810126582279, Blast_Score=193, Evalue=7e-49,
Organism=Homo sapiens, GI190014623, Length=632, Percent_Identity=28.4810126582279, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI134288890, Length=412, Percent_Identity=29.8543689320388, Blast_Score=156, Evalue=8e-38,
Organism=Homo sapiens, GI19115966, Length=475, Percent_Identity=26.5263157894737, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI219521928, Length=475, Percent_Identity=26.5263157894737, Blast_Score=139, Evalue=8e-33,
Organism=Escherichia coli, GI87082383, Length=747, Percent_Identity=42.570281124498, Blast_Score=588, Evalue=1e-169,
Organism=Escherichia coli, GI1787542, Length=666, Percent_Identity=26.4264264264264, Blast_Score=183, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI212645896, Length=439, Percent_Identity=29.3849658314351, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17553506, Length=383, Percent_Identity=32.1148825065274, Blast_Score=155, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6324552, Length=503, Percent_Identity=27.8330019880716, Blast_Score=174, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6323943, Length=405, Percent_Identity=24.1975308641975, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24649634, Length=493, Percent_Identity=30.4259634888438, Blast_Score=192, Evalue=6e-49,
Organism=Drosophila melanogaster, GI19922976, Length=362, Percent_Identity=29.0055248618785, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24654597, Length=362, Percent_Identity=29.0055248618785, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24654592, Length=362, Percent_Identity=29.0055248618785, Blast_Score=138, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91144; Mature: 91012

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNWVDPEAKAEAERYDNPIPSRTLILDTLEQLQTPQSHAELVDHFHIQDQKSIEALSH
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
RLSAMVRDGQLMKDGFKFQLVADQPTYEATVYINSKGLGTAHIDGQDDLLLPERELRLVF
HHHHHHHCCHHHHCCCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEE
NGDRVRVRQTSVDRKGKPWGFITEVIQHRVKQLIGKLSVHDGEYFIQPNNPNQHQPIPLE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCCCHH
KELVEHAKANVGDMLRVAIDTYPTREEFATAHIIQSMADKADTEIIIPQTILEFGLPYEF
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECHHHHHHHCCCCCC
PDEVIKEAESFKEPAEQDREGRVDLRDLALVTIDGEDARDFDDAVYAEKRPGGGYRVVVA
HHHHHHHHHHHHCHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEE
IADVSHYVRLDSALNEEAEERGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLK
EECHHHHHHHHHHHCHHHHHCCCEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCE
LSRTGRVTGYEFYPAVMHSKARLTYTQVGQYFEGATDAIPKDRDIHKSLNTLFQLYQILK
ECCCCCCCCEEHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NLRVDRHAMEFETIETYMTFDELGGIKEILPRTRNDAHKLIEECMLLANVAAAEYALEHD
HCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
IPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQKVIEATKDRIDAPSIHAVLL
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
RSMMQAYYGAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLKQKPYPLSGAALDD
HHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AGEHFSQTERRADEASRSVTTWLKCHYMQQHLGDEFIGIVSAVTEFGLFVTLKDLYVDGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEHHHHHHCCH
IHISQLGDDFFIYDQASQNLIGQNRGQVFGLGDEVKIQVAGVNLEERKIDFQLIKQVTHA
HHHHHCCCCEEEEECCCCHHHCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHH
GRVVRSRAPRTTKTSTQATEEVFGKPSVSTDGEKPVRKKKEKGKPSSYSKKSGKKTSTKA
HHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
EAKPEKVKKKAKPKKKKSNAKSKAD
CCCHHHHHHHCCCCHHHCCCCCCCC
>Mature Secondary Structure 
TKNWVDPEAKAEAERYDNPIPSRTLILDTLEQLQTPQSHAELVDHFHIQDQKSIEALSH
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
RLSAMVRDGQLMKDGFKFQLVADQPTYEATVYINSKGLGTAHIDGQDDLLLPERELRLVF
HHHHHHHCCHHHHCCCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCEEEEE
NGDRVRVRQTSVDRKGKPWGFITEVIQHRVKQLIGKLSVHDGEYFIQPNNPNQHQPIPLE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCCCHH
KELVEHAKANVGDMLRVAIDTYPTREEFATAHIIQSMADKADTEIIIPQTILEFGLPYEF
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECHHHHHHHCCCCCC
PDEVIKEAESFKEPAEQDREGRVDLRDLALVTIDGEDARDFDDAVYAEKRPGGGYRVVVA
HHHHHHHHHHHHCHHHHCCCCCCEEEEEEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEE
IADVSHYVRLDSALNEEAEERGTSVYFPHFVLPMLPEALSNGLCSLNPHVDRLCMVCDLK
EECHHHHHHHHHHHCHHHHHCCCEEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCE
LSRTGRVTGYEFYPAVMHSKARLTYTQVGQYFEGATDAIPKDRDIHKSLNTLFQLYQILK
ECCCCCCCCEEHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NLRVDRHAMEFETIETYMTFDELGGIKEILPRTRNDAHKLIEECMLLANVAAAEYALEHD
HCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
IPMLYRVHEAPEFSRIQKVKDFVKLLGLPFPDQPTQADYQKVIEATKDRIDAPSIHAVLL
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
RSMMQAYYGAKNAGHYGLAYEAYTHFTSPIRRYPDLLLHRAIKAHLKQKPYPLSGAALDD
HHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
AGEHFSQTERRADEASRSVTTWLKCHYMQQHLGDEFIGIVSAVTEFGLFVTLKDLYVDGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEHHHHHHCCH
IHISQLGDDFFIYDQASQNLIGQNRGQVFGLGDEVKIQVAGVNLEERKIDFQLIKQVTHA
HHHHHCCCCEEEEECCCCHHHCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHH
GRVVRSRAPRTTKTSTQATEEVFGKPSVSTDGEKPVRKKKEKGKPSSYSKKSGKKTSTKA
HHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
EAKPEKVKKKAKPKKKKSNAKSKAD
CCCHHHHHHHCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]