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The map label for this gene is cfa [H]

Identifier: 213158590

GI number: 213158590

Start: 2637570

End: 2639402

Strand: Reverse

Name: cfa [H]

Synonym: AB57_2544

Alternate gene names: 213158590

Gene position: 2639402-2637570 (Counterclockwise)

Preceding gene: 213158591

Following gene: 213158588

Centisome position: 65.16

GC content: 39.28

Gene sequence:

>1833_bases
ATGTTTTGGAATTTACTGATTCTAGATTTAATGATCATGTTGCTGAGCTGGCTACTTGCCACTCTAAATGGCAGAGCTGG
AATTGTAGATGCTGCATGGAGTTTCTGTCTGGCAGTAAACATTATCGTGTCTTCTTTACTCATTTCAGTTGCCCCAGTTG
AAGTGCGTCTTTTTATCGGTATTTTTAGCGGCTTATGGTTTTTAAGATTATTTTGGCACCTGTTAAGACGTTATCAATCT
GAACAAAAAGAAGATGGCCGTTACGCGAGCATGCGTAAAGCGATGGGTAAGTTTCAGCATATTGGCTTTTTATTCTTTTT
TATCTTTCAAACACTTTTAGTGCTTTTGTTCTTTTTACCGATGTGGACGCTACTCAATGTAGAGGCAACTGAATGGAGTA
GTGGATATAAAGTCGCTTTAGTAATTGCTGCTGTCATCATGGCAATTGCTTTCATGGGAGAGCAGCTCGCTGATCAGCAG
TTATACCGATTTAAATTAAATCCAGATCATCATGGCAAAACGATGGATCAGGGTTTATGGCGTTATTCACGTCACCCCAA
TTATTTTTTTGAATGGTTACACTGGTTTGCCTATCCAATTATTGGTTTAGCGGCAGGCCAATATGTATTGTGGATTTATC
CGTTACTGATGTGGCTATTTTTATATTACGTCACGGGTATTCCATTTAGTGAAAAACAAGCAATTAAAAGTCGCGGTCAA
AATTATCTTGATTATCAACAAAAAACATCAATGTTTATTCCGCGAAAACCAAAAAATGGTGCGTATATGGATTTTATTGT
TCATCAGTCTTTGAAAATTGTTGAAAGTGGTGTGATTCCAGATCATGCAATTCGAGCTGCAATTCGAGCTTTAAGTAAAA
AGCGCTTAATCCAAGAAGGCCGTTATGACCCTGAACAAGGGGCGCATCGCTACATGGATGTGCTTAATATGCTGAAGAAG
AGCGAAATCGCGGTTGAAACGGATAAGGCAAATGAGCAGCACTATGAATTGCCGACCGAGTTTTTTCAGGCGGTGCTTGG
AAAAAGACTCAAATATAGTGCGTGCTATTTCCCGACTAAAACGACAACTTTAGATCAGGCAGAAGAGTTGGCTCTTCAGA
TTTATTGTGAAAGAGCACAACTTAAAAACGGTCAACAGATTTTAGAGTTAGGCTGTGGCTGGGGTTCTTTAACTTTGTGG
ATGGCAGAAAACTATCCACGCTCACAGATTACTGCTGTTTCAAATTCTGCAACGCAGAAAAAGCATATTCTTCGGCAAGC
AGAATTGAGAGGTTTAACCAATGTTGAAGTGCTTACCTGTGATGTGAATGTACTCGACTTGGACCAAGACAAGTTTGATC
GTGTTGTATCGGTCGAAATGTTTGAACATGTTCGTAATTACCAACTTCTTTTTGAAAAAATTCAGGGCTGGTTAAAGGCA
GACGGCTTACTTTGGTGTCATATTTTTTGCCATCGCTTTTTACATTATCCTTTTGAAGTGAAATCAGATTATGATTGGAT
GTCCAAGTATTTCTTTACTGGTGGTTTAATGCCTTCGACTTCGACTTTTTTGCATTTTCAAGAGCATTTAGAGTTGACCC
AACAGTGGCAATGGTCGGGTGAGCACTATATGAGAACGGCAAATGCTTGGCTTGAGAATATGGATAACCAAGAAGTCGAA
CTGAAACCACTGTTTAAAAAAATCTATGGAAAAGATGCCAATATTTGGTGGCAACGCTGGCGTATTTTCTTCATGGCTTG
TGCTGAGCTATTCGGTTTTGAGCAAGGACAAGAATGGGTCATTGGTCACTTTTTATTTAAAAAGCGATCATAG

Upstream 100 bases:

>100_bases
ATTGCGAAGGTGGTTTTAAAGAAGGCGTGATAAGCAATGTTCACTTGTTGTTTGAAAGTACCAGTTACTAAATCAAACAG
CTCAAGTAAGGAGACTGCTC

Downstream 100 bases:

>100_bases
TAATTTCTATAGCCTATCCCGACGATAAAGATATGATAAGAACTCGACATGATGGCAAAACGAGTCATCCATTAGCCCAA
ATGTTCAATCGATATTACTG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MFWNLLILDLMIMLLSWLLATLNGRAGIVDAAWSFCLAVNIIVSSLLISVAPVEVRLFIGIFSGLWFLRLFWHLLRRYQS
EQKEDGRYASMRKAMGKFQHIGFLFFFIFQTLLVLLFFLPMWTLLNVEATEWSSGYKVALVIAAVIMAIAFMGEQLADQQ
LYRFKLNPDHHGKTMDQGLWRYSRHPNYFFEWLHWFAYPIIGLAAGQYVLWIYPLLMWLFLYYVTGIPFSEKQAIKSRGQ
NYLDYQQKTSMFIPRKPKNGAYMDFIVHQSLKIVESGVIPDHAIRAAIRALSKKRLIQEGRYDPEQGAHRYMDVLNMLKK
SEIAVETDKANEQHYELPTEFFQAVLGKRLKYSACYFPTKTTTLDQAEELALQIYCERAQLKNGQQILELGCGWGSLTLW
MAENYPRSQITAVSNSATQKKHILRQAELRGLTNVEVLTCDVNVLDLDQDKFDRVVSVEMFEHVRNYQLLFEKIQGWLKA
DGLLWCHIFCHRFLHYPFEVKSDYDWMSKYFFTGGLMPSTSTFLHFQEHLELTQQWQWSGEHYMRTANAWLENMDNQEVE
LKPLFKKIYGKDANIWWQRWRIFFMACAELFGFEQGQEWVIGHFLFKKRS

Sequences:

>Translated_610_residues
MFWNLLILDLMIMLLSWLLATLNGRAGIVDAAWSFCLAVNIIVSSLLISVAPVEVRLFIGIFSGLWFLRLFWHLLRRYQS
EQKEDGRYASMRKAMGKFQHIGFLFFFIFQTLLVLLFFLPMWTLLNVEATEWSSGYKVALVIAAVIMAIAFMGEQLADQQ
LYRFKLNPDHHGKTMDQGLWRYSRHPNYFFEWLHWFAYPIIGLAAGQYVLWIYPLLMWLFLYYVTGIPFSEKQAIKSRGQ
NYLDYQQKTSMFIPRKPKNGAYMDFIVHQSLKIVESGVIPDHAIRAAIRALSKKRLIQEGRYDPEQGAHRYMDVLNMLKK
SEIAVETDKANEQHYELPTEFFQAVLGKRLKYSACYFPTKTTTLDQAEELALQIYCERAQLKNGQQILELGCGWGSLTLW
MAENYPRSQITAVSNSATQKKHILRQAELRGLTNVEVLTCDVNVLDLDQDKFDRVVSVEMFEHVRNYQLLFEKIQGWLKA
DGLLWCHIFCHRFLHYPFEVKSDYDWMSKYFFTGGLMPSTSTFLHFQEHLELTQQWQWSGEHYMRTANAWLENMDNQEVE
LKPLFKKIYGKDANIWWQRWRIFFMACAELFGFEQGQEWVIGHFLFKKRS
>Mature_610_residues
MFWNLLILDLMIMLLSWLLATLNGRAGIVDAAWSFCLAVNIIVSSLLISVAPVEVRLFIGIFSGLWFLRLFWHLLRRYQS
EQKEDGRYASMRKAMGKFQHIGFLFFFIFQTLLVLLFFLPMWTLLNVEATEWSSGYKVALVIAAVIMAIAFMGEQLADQQ
LYRFKLNPDHHGKTMDQGLWRYSRHPNYFFEWLHWFAYPIIGLAAGQYVLWIYPLLMWLFLYYVTGIPFSEKQAIKSRGQ
NYLDYQQKTSMFIPRKPKNGAYMDFIVHQSLKIVESGVIPDHAIRAAIRALSKKRLIQEGRYDPEQGAHRYMDVLNMLKK
SEIAVETDKANEQHYELPTEFFQAVLGKRLKYSACYFPTKTTTLDQAEELALQIYCERAQLKNGQQILELGCGWGSLTLW
MAENYPRSQITAVSNSATQKKHILRQAELRGLTNVEVLTCDVNVLDLDQDKFDRVVSVEMFEHVRNYQLLFEKIQGWLKA
DGLLWCHIFCHRFLHYPFEVKSDYDWMSKYFFTGGLMPSTSTFLHFQEHLELTQQWQWSGEHYMRTANAWLENMDNQEVE
LKPLFKKIYGKDANIWWQRWRIFFMACAELFGFEQGQEWVIGHFLFKKRS

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=257, Percent_Identity=31.9066147859922, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI133904226, Length=282, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281365853, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28574404, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355723, Length=250, Percent_Identity=28.4, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 71874; Mature: 71874

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50244 S5A_REDUCTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCC
>Mature Secondary Structure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HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]