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The map label for this gene is cfa [H]

Identifier: 213158591

GI number: 213158591

Start: 2639432

End: 2640631

Strand: Reverse

Name: cfa [H]

Synonym: AB57_2545

Alternate gene names: 213158591

Gene position: 2640631-2639432 (Counterclockwise)

Preceding gene: 213158592

Following gene: 213158590

Centisome position: 65.19

GC content: 38.92

Gene sequence:

>1200_bases
ATGATAAAAACATTTCTTTATGGTGAAGATGACTCACTGCCGTTATTGCTCAAGAGTCTTCTCAAACTACGTCATGGACA
GATCACTTTTCAGGGCGCGTGGAATGGGACGGTCGGTGAAGTTTCAGACTTACATGCTGTGATTGAAGTTCACAATCCTT
TATTGATGGATCTCATTTTAAAAAATGGTGTTTTGGGAGCAGCAGAAGGCTACATCCGTGGTGACTGGAGCAGCGAGCAC
CTTGTCGAGTTGATTCAGATCTTGGCACGTAATCGAGCTGTATTGGACCAAATCAACCAGAATGTTATTGCTCAAGCGAG
CCAGTTTTTTCTTAAAGCGTGGTATCAAAATCGAAAGAACTCTATAAGTGGTAGCCGTAAAAATATTGCCGAGCACTACG
ACTTAAGCAACGACTTTTTTAAATTATTTTTAGATCCATCTTTAATGTATTCGAGCGCCGTTTTTGAAAATGAAAACATG
ACTCTCGAAGAAGCATCTGATTTAAAAAAAGAGATCATTTGTAAAAAGTTAGATTTAAAACCACTAGATCATTTAGTTGA
AATTGGAAGTGGATGGGGTGGTTTTGCCATTTATGCAGCTCAACATTATGGCTGTAGAGTAACCACCATTACCATTTCAC
AAGCTCAATATGATGAAGCCGTTACTCGTGTAAATGAAGCTGGCTTGGCGCATCGAATTGATGTGCAACTTGAAGACTAC
CGTTTGCTCGAAGGCAAGTTCGATAAGCTGGTTTCAATTGAAATGGTTGAGGCAGTTGGTGCGCAATATTTATCGACATA
CTTTGATCAATGTAAAGCACTCTTAAAACCGAAAGGCTTGGCATTTATTCAAGCCATTATTATTGAAGATTTCCGATATA
AAAAAGCATTAAATACAGTTGATTATATTAAGCGCTATATTTTCCCAGGTAGTTTTATCCCTAGCGTGAGTGTGTTGACT
CAAACCGCCTCTGAGAGTGGTTTAAGGTTAAAGCATTTAAATGATATTGGTTTAAGTTATGCGCACACACTTCATCACTG
GCGAGCGCGGTTTTTAGCAGCGCGGGAACAAGTATTGGCTCTAGGTTTTGATGAAAACTTCATTCGCATGTGGGATTTTT
ATTTATGTTATTGCGAAGGTGGTTTTAAAGAAGGCGTGATAAGCAATGTTCACTTGTTGTTTGAAAGTACCAGTTACTAA

Upstream 100 bases:

>100_bases
CTTTTAAAATGTTGTTTTCAATATATTTAGAGGCATTTAAGTTGTGGCGAAAAAAAGTTCCATTTTATCGTCATCCTAAA
AAGATCAAGGTAGATAAGAC

Downstream 100 bases:

>100_bases
ATCAAACAGCTCAAGTAAGGAGACTGCTCATGTTTTGGAATTTACTGATTCTAGATTTAATGATCATGTTGCTGAGCTGG
CTACTTGCCACTCTAAATGG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIKTFLYGEDDSLPLLLKSLLKLRHGQITFQGAWNGTVGEVSDLHAVIEVHNPLLMDLILKNGVLGAAEGYIRGDWSSEH
LVELIQILARNRAVLDQINQNVIAQASQFFLKAWYQNRKNSISGSRKNIAEHYDLSNDFFKLFLDPSLMYSSAVFENENM
TLEEASDLKKEIICKKLDLKPLDHLVEIGSGWGGFAIYAAQHYGCRVTTITISQAQYDEAVTRVNEAGLAHRIDVQLEDY
RLLEGKFDKLVSIEMVEAVGAQYLSTYFDQCKALLKPKGLAFIQAIIIEDFRYKKALNTVDYIKRYIFPGSFIPSVSVLT
QTASESGLRLKHLNDIGLSYAHTLHHWRARFLAAREQVLALGFDENFIRMWDFYLCYCEGGFKEGVISNVHLLFESTSY

Sequences:

>Translated_399_residues
MIKTFLYGEDDSLPLLLKSLLKLRHGQITFQGAWNGTVGEVSDLHAVIEVHNPLLMDLILKNGVLGAAEGYIRGDWSSEH
LVELIQILARNRAVLDQINQNVIAQASQFFLKAWYQNRKNSISGSRKNIAEHYDLSNDFFKLFLDPSLMYSSAVFENENM
TLEEASDLKKEIICKKLDLKPLDHLVEIGSGWGGFAIYAAQHYGCRVTTITISQAQYDEAVTRVNEAGLAHRIDVQLEDY
RLLEGKFDKLVSIEMVEAVGAQYLSTYFDQCKALLKPKGLAFIQAIIIEDFRYKKALNTVDYIKRYIFPGSFIPSVSVLT
QTASESGLRLKHLNDIGLSYAHTLHHWRARFLAAREQVLALGFDENFIRMWDFYLCYCEGGFKEGVISNVHLLFESTSY
>Mature_399_residues
MIKTFLYGEDDSLPLLLKSLLKLRHGQITFQGAWNGTVGEVSDLHAVIEVHNPLLMDLILKNGVLGAAEGYIRGDWSSEH
LVELIQILARNRAVLDQINQNVIAQASQFFLKAWYQNRKNSISGSRKNIAEHYDLSNDFFKLFLDPSLMYSSAVFENENM
TLEEASDLKKEIICKKLDLKPLDHLVEIGSGWGGFAIYAAQHYGCRVTTITISQAQYDEAVTRVNEAGLAHRIDVQLEDY
RLLEGKFDKLVSIEMVEAVGAQYLSTYFDQCKALLKPKGLAFIQAIIIEDFRYKKALNTVDYIKRYIFPGSFIPSVSVLT
QTASESGLRLKHLNDIGLSYAHTLHHWRARFLAAREQVLALGFDENFIRMWDFYLCYCEGGFKEGVISNVHLLFESTSY

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=354, Percent_Identity=35.0282485875706, Blast_Score=178, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI133904226, Length=381, Percent_Identity=35.1706036745407, Blast_Score=226, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 45326; Mature: 45326

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTFLYGEDDSLPLLLKSLLKLRHGQITFQGAWNGTVGEVSDLHAVIEVHNPLLMDLIL
CCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHH
KNGVLGAAEGYIRGDWSSEHLVELIQILARNRAVLDQINQNVIAQASQFFLKAWYQNRKN
HCCCCCCCCCCEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SISGSRKNIAEHYDLSNDFFKLFLDPSLMYSSAVFENENMTLEEASDLKKEIICKKLDLK
CCCCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
PLDHLVEIGSGWGGFAIYAAQHYGCRVTTITISQAQYDEAVTRVNEAGLAHRIDVQLEDY
HHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEEEEEECCC
RLLEGKFDKLVSIEMVEAVGAQYLSTYFDQCKALLKPKGLAFIQAIIIEDFRYKKALNTV
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DYIKRYIFPGSFIPSVSVLTQTASESGLRLKHLNDIGLSYAHTLHHWRARFLAAREQVLA
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LGFDENFIRMWDFYLCYCEGGFKEGVISNVHLLFESTSY
ECCCCCHHHHHHHEEEEECCCCCCCHHHHEEEEEECCCC
>Mature Secondary Structure
MIKTFLYGEDDSLPLLLKSLLKLRHGQITFQGAWNGTVGEVSDLHAVIEVHNPLLMDLIL
CCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHH
KNGVLGAAEGYIRGDWSSEHLVELIQILARNRAVLDQINQNVIAQASQFFLKAWYQNRKN
HCCCCCCCCCCEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SISGSRKNIAEHYDLSNDFFKLFLDPSLMYSSAVFENENMTLEEASDLKKEIICKKLDLK
CCCCCHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
PLDHLVEIGSGWGGFAIYAAQHYGCRVTTITISQAQYDEAVTRVNEAGLAHRIDVQLEDY
HHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEEEEEECCC
RLLEGKFDKLVSIEMVEAVGAQYLSTYFDQCKALLKPKGLAFIQAIIIEDFRYKKALNTV
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DYIKRYIFPGSFIPSVSVLTQTASESGLRLKHLNDIGLSYAHTLHHWRARFLAAREQVLA
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LGFDENFIRMWDFYLCYCEGGFKEGVISNVHLLFESTSY
ECCCCCHHHHHHHEEEEECCCCCCCHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]