Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 213158428

GI number: 213158428

Start: 2462192

End: 2464252

Strand: Reverse

Name: dnaX [H]

Synonym: AB57_2377

Alternate gene names: 213158428

Gene position: 2464252-2462192 (Counterclockwise)

Preceding gene: 213158429

Following gene: 213158427

Centisome position: 60.84

GC content: 40.27

Gene sequence:

>2061_bases
ATGTATCAAGTACTTGCTAGAAAATACCGTCCACGTAATTTCAATGAGTTAGTGGGACAAAACCATGTTTCTCGTGCATT
AAGTAGTGCATTGGAACGCGGTCGTCTTCACCATGCTTATTTATTTACAGGAACGCGTGGTGTAGGTAAAACTACAATTG
CACGTATTTTAGCCAAGTGTTTGAACTGTGAAACAGGTGTGACTTCTACGCCATGTGAAGTTTGTGCCACTTGTAAGGCG
GTAAATGAAGGCCGCTTTATTGACCTAATCGAAATCGATGCTGCTTCAAGAACAAAAGTAGAAGATACGCGTGAACTTTT
AGACAACGTTCCTTATGCACCAACTCAAGGCCGTTTTAAAGTTTACCTGATTGATGAAGTACATATGCTCTCTACGCATT
CTTTTAATGCGTTATTAAAAACACTAGAAGAACCACCAGAACACGTTAAGTTTTTATTTGCTACGACAGACCCACAAAAG
TTACCAATTACGGTTATTTCACGTTGTTTGCAATTTACTCTACGACCTTTAGCTGTCGATGAAATTACCAAGCACCTCGG
TGCTATTCTTGAAAAAGAACAGATTACTGCTGATCAAGATGCAATTTGGCAAATTGCCGAATCTGCACAAGGCTCTTTAC
GTGATGCATTATCTTTAACTGACCAAGCCATTGCTTATGGGCAGGGAGCTGTACATCATCAAGATGTTAAAGAAATGCTT
GGCTTGATTGACCGTACGATCATATATGATTTGATTTTAGCGGTTCATCAAAACCAACGTGAAAAAGTGAGCCAGTTATT
ACTCCAATTTAGATATCAAGCCTTAGATGTCTCGTTAGTACTGGATCAGCTCATTTCAACATTGCATGAGTTGGCTTTAT
TACAATATTTACCAGAGCTCGGCTTAAAGTATAGTGAAGAAATTAATGCCAAAATTCTTCAGCTTTCTAAACTGATTTCT
GCTCAAGATTTGCAGCTTTACTACCAAATCGCATGTAAAGGCCGGTCAGACTTGCAGCTTGCCGTAACGCAAGAGCAAGG
TTTTGAAATGTGCGTTTTACGATTATTGGCATTCCGTCCTTTAGCACCAAATGAAATTTTAGTTTCAGAGCCTGTTCAAC
AAAATGGGCAAGCAGAAGTAGGCCTAAATTCACAAGCTCAAACAGCCCAAGAGATTACTCCTATAAGTGCTGTTCAGCCT
GTTGAAGTTATTAGTCAACCCGCTATGGTTGAACCTGAACCTGAACCTGAACCTGAACCTGAACCTGAACCTGAACCTCA
GCCTAATCAGGACTTAATGGTATTTGACCCAAATCATCATGAGTTGATTGGACTTGAGTCAGCAGTTGTTCAAGAGACTG
TTAGTGTTCTTGAGGAAGATTTCATTCCGGTACCAGAACAAAAGTTAGTACAAGTTCAGGCTGAAACCCAAGTCAGACAA
ATCGAACCTGAACCAGCTTCTACTGCTGAGCCTATAGGTTTATTTGAAGCATCGAATGCTGAATTTTCACTAGCTCAAGA
TACGTCAGCTTATGACTTGGTTTCTGAACCTGTTATTGAACAACAGTCATTGGTGCAAGCTGAAATTGTTGAAACAGTTG
CGGTGGTAAAAGAGCCTAACGCAACAGATAACAGCCAGCTGATGCCACAAGATATTTTAAAGTTGCCATCACAAACTTTG
GAAGGTGAGTGGACACTTGAAAAGTGGGAGTTTTGGTTTAGAAATAGCCAGCTTTCTCCAGCCGTTCAAGAACTTGCTCA
ACATGGTGTGATGACTGGAGAAATTGGTGGCAACACGGTTTTCCATATTCCTCAAGAATATGAAAATATGTTGACTCAGC
TACAACAAGCCCTAATTGAAGCTTTAAAGCAGCAGTGGCCAAATACACAATTTACGGTCGAGTATGGTGCAGTCAATACT
GCTACACCGTATGTTATGCAAAGCGTTCGTAAAGAAAAAGCTTTCCATCGGGCTACAGAACTATTACAGCAACAACCCGT
TATTAAAAGCCTCATAGAGACTTTTGATGGTGAGCTGCAAAATATTCAATTAAAGCCTTAA

Upstream 100 bases:

>100_bases
CAAATGATGTAGTTCGCAGTTTATCTGTACGGATATGAGCTTTATACGTTCACACTCTTTTAAAAACAAAGTATGCTTAT
GCCTGTAACAAGGAGCATAC

Downstream 100 bases:

>100_bases
GTTCAATTGAGTTTTGATCTGGTGAGAAACTTGAAAAAATAGAATTTTCATAGTTTTCACTGGATTGAAATATTCAGGTC
ACGCCACTGTCATTGTACTT

Product: DNA polymerase III subunit tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MYQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKA
VNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQK
LPITVISRCLQFTLRPLAVDEITKHLGAILEKEQITADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEML
GLIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEEINAKILQLSKLIS
AQDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRPLAPNEILVSEPVQQNGQAEVGLNSQAQTAQEITPISAVQP
VEVISQPAMVEPEPEPEPEPEPEPEPQPNQDLMVFDPNHHELIGLESAVVQETVSVLEEDFIPVPEQKLVQVQAETQVRQ
IEPEPASTAEPIGLFEASNAEFSLAQDTSAYDLVSEPVIEQQSLVQAEIVETVAVVKEPNATDNSQLMPQDILKLPSQTL
EGEWTLEKWEFWFRNSQLSPAVQELAQHGVMTGEIGGNTVFHIPQEYENMLTQLQQALIEALKQQWPNTQFTVEYGAVNT
ATPYVMQSVRKEKAFHRATELLQQQPVIKSLIETFDGELQNIQLKP

Sequences:

>Translated_686_residues
MYQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKA
VNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQK
LPITVISRCLQFTLRPLAVDEITKHLGAILEKEQITADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEML
GLIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEEINAKILQLSKLIS
AQDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRPLAPNEILVSEPVQQNGQAEVGLNSQAQTAQEITPISAVQP
VEVISQPAMVEPEPEPEPEPEPEPEPQPNQDLMVFDPNHHELIGLESAVVQETVSVLEEDFIPVPEQKLVQVQAETQVRQ
IEPEPASTAEPIGLFEASNAEFSLAQDTSAYDLVSEPVIEQQSLVQAEIVETVAVVKEPNATDNSQLMPQDILKLPSQTL
EGEWTLEKWEFWFRNSQLSPAVQELAQHGVMTGEIGGNTVFHIPQEYENMLTQLQQALIEALKQQWPNTQFTVEYGAVNT
ATPYVMQSVRKEKAFHRATELLQQQPVIKSLIETFDGELQNIQLKP
>Mature_686_residues
MYQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKA
VNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQK
LPITVISRCLQFTLRPLAVDEITKHLGAILEKEQITADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEML
GLIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEEINAKILQLSKLIS
AQDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRPLAPNEILVSEPVQQNGQAEVGLNSQAQTAQEITPISAVQP
VEVISQPAMVEPEPEPEPEPEPEPEPQPNQDLMVFDPNHHELIGLESAVVQETVSVLEEDFIPVPEQKLVQVQAETQVRQ
IEPEPASTAEPIGLFEASNAEFSLAQDTSAYDLVSEPVIEQQSLVQAEIVETVAVVKEPNATDNSQLMPQDILKLPSQTL
EGEWTLEKWEFWFRNSQLSPAVQELAQHGVMTGEIGGNTVFHIPQEYENMLTQLQQALIEALKQQWPNTQFTVEYGAVNT
ATPYVMQSVRKEKAFHRATELLQQQPVIKSLIETFDGELQNIQLKP

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=222, Percent_Identity=25.2252252252252, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI194306571, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI194306567, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI31563534, Length=321, Percent_Identity=24.6105919003115, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1786676, Length=362, Percent_Identity=55.8011049723757, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1787119, Length=285, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71986063, Length=236, Percent_Identity=26.6949152542373, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322528, Length=288, Percent_Identity=23.9583333333333, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324039, Length=215, Percent_Identity=26.046511627907, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324478, Length=306, Percent_Identity=21.8954248366013, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI18859927, Length=295, Percent_Identity=24.406779661017, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19921076, Length=237, Percent_Identity=24.0506329113924, Blast_Score=67, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17647857, Length=320, Percent_Identity=23.75, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 76888; Mature: 76888

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKC
CHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
LNCETGVTSTPCEVCATCKAVNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFK
HCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEE
VYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRCLQFTLRPLAVD
EEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHH
EITKHLGAILEKEQITADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEML
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GLIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPEL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKYSEEINAKILQLSKLISAQDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRP
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHCC
LAPNEILVSEPVQQNGQAEVGLNSQAQTAQEITPISAVQPVEVISQPAMVEPEPEPEPEP
CCCCCEEECCCHHCCCCEEECCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
EPEPEPQPNQDLMVFDPNHHELIGLESAVVQETVSVLEEDFIPVPEQKLVQVQAETQVRQ
CCCCCCCCCCCEEEECCCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IEPEPASTAEPIGLFEASNAEFSLAQDTSAYDLVSEPVIEQQSLVQAEIVETVAVVKEPN
CCCCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
ATDNSQLMPQDILKLPSQTLEGEWTLEKWEFWFRNSQLSPAVQELAQHGVMTGEIGGNTV
CCCCCCCCHHHHHHCCHHHCCCCEEHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCEE
FHIPQEYENMLTQLQQALIEALKQQWPNTQFTVEYGAVNTATPYVMQSVRKEKAFHRATE
EECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LLQQQPVIKSLIETFDGELQNIQLKP
HHHHCHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure
MYQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKC
CHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
LNCETGVTSTPCEVCATCKAVNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFK
HCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEE
VYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRCLQFTLRPLAVD
EEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHH
EITKHLGAILEKEQITADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEML
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GLIDRTIIYDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPEL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLKYSEEINAKILQLSKLISAQDLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFRP
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHCC
LAPNEILVSEPVQQNGQAEVGLNSQAQTAQEITPISAVQPVEVISQPAMVEPEPEPEPEP
CCCCCEEECCCHHCCCCEEECCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
EPEPEPQPNQDLMVFDPNHHELIGLESAVVQETVSVLEEDFIPVPEQKLVQVQAETQVRQ
CCCCCCCCCCCEEEECCCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
IEPEPASTAEPIGLFEASNAEFSLAQDTSAYDLVSEPVIEQQSLVQAEIVETVAVVKEPN
CCCCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCC
ATDNSQLMPQDILKLPSQTLEGEWTLEKWEFWFRNSQLSPAVQELAQHGVMTGEIGGNTV
CCCCCCCCHHHHHHCCHHHCCCCEEHHHHHHHHCCCCCCHHHHHHHHCCCEEEECCCCEE
FHIPQEYENMLTQLQQALIEALKQQWPNTQFTVEYGAVNTATPYVMQSVRKEKAFHRATE
EECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LLQQQPVIKSLIETFDGELQNIQLKP
HHHHCHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]