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The map label for this gene is moaE [H]

Identifier: 213158398

GI number: 213158398

Start: 2426215

End: 2426700

Strand: Reverse

Name: moaE [H]

Synonym: AB57_2346

Alternate gene names: 213158398

Gene position: 2426700-2426215 (Counterclockwise)

Preceding gene: 213158399

Following gene: 213158397

Centisome position: 59.91

GC content: 40.95

Gene sequence:

>486_bases
ATGCGAGATTTTGCACGTATACAAGAGCAGGCTTTAAGCCTTGATATCTTTGATTCGATTGAATCATTTCCTGAATGCGG
TGGAGTTGATATTTTTATGGGTACGGTTCGTAATCATCATGAAGGTAAAGCTGTTAAAGCATTGAAATATACCTCGTATA
AACCGCTTTCTGAAAAAATGATACGTGAAATTGAACTGGAAATTGAGAAAAAGTATCAGGTATCTTATGTGCGAGTGGTT
CATCGGATTGGATATTTAGATGTTGGCGAAACAGCCATTATTGCAATTGCTTATGCAGCCCATCGCCGTGAAGCTTTTCA
AGCATGCGAAGAAGCGGTTGAGCGGGTAAAACATGAAGTGCCTGTGTTTAAAGAAGAATTCTTTACAGATGGCACGAGTC
ATTATGTAGAGGGCTGTTGTATTCGTAAGGATGCACCGCACGACCACAAACATCACCATCATACCGGCCATGAACACTCA
CACTGA

Upstream 100 bases:

>100_bases
ATGTGCATGTGCGATAGAGGATAACGTTATAACCAGACAATCTGCCTTAAATCAGCCATGTACTTTGGTTTTATTATCAC
CAGTTGCAGGAGGATGAGCC

Downstream 100 bases:

>100_bases
AATAAGCAAGACTAGGATAAATAATGAAAAACGTAGGAATGAAGCCGGAAAGTTATCGTGTTGCTGAAGCACAAGCGATT
TTATATGCACCACCACACTG

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MRDFARIQEQALSLDIFDSIESFPECGGVDIFMGTVRNHHEGKAVKALKYTSYKPLSEKMIREIELEIEKKYQVSYVRVV
HRIGYLDVGETAIIAIAYAAHRREAFQACEEAVERVKHEVPVFKEEFFTDGTSHYVEGCCIRKDAPHDHKHHHHTGHEHS
H

Sequences:

>Translated_161_residues
MRDFARIQEQALSLDIFDSIESFPECGGVDIFMGTVRNHHEGKAVKALKYTSYKPLSEKMIREIELEIEKKYQVSYVRVV
HRIGYLDVGETAIIAIAYAAHRREAFQACEEAVERVKHEVPVFKEEFFTDGTSHYVEGCCIRKDAPHDHKHHHHTGHEHS
H
>Mature_161_residues
MRDFARIQEQALSLDIFDSIESFPECGGVDIFMGTVRNHHEGKAVKALKYTSYKPLSEKMIREIELEIEKKYQVSYVRVV
HRIGYLDVGETAIIAIAYAAHRREAFQACEEAVERVKHEVPVFKEEFFTDGTSHYVEGCCIRKDAPHDHKHHHHTGHEHS
H

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=133, Percent_Identity=33.0827067669173, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1787003, Length=113, Percent_Identity=35.3982300884956, Blast_Score=69, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509279, Length=132, Percent_Identity=30.3030303030303, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356259, Length=115, Percent_Identity=29.5652173913043, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18628; Mature: 18628

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFARIQEQALSLDIFDSIESFPECGGVDIFMGTVRNHHEGKAVKALKYTSYKPLSEKM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCHHHHHHHCCCCCCHHHHH
IREIELEIEKKYQVSYVRVVHRIGYLDVGETAIIAIAYAAHRREAFQACEEAVERVKHEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PVFKEEFFTDGTSHYVEGCCIRKDAPHDHKHHHHTGHEHSH
CHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDFARIQEQALSLDIFDSIESFPECGGVDIFMGTVRNHHEGKAVKALKYTSYKPLSEKM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCHHHHHHHCCCCCCHHHHH
IREIELEIEKKYQVSYVRVVHRIGYLDVGETAIIAIAYAAHRREAFQACEEAVERVKHEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PVFKEEFFTDGTSHYVEGCCIRKDAPHDHKHHHHTGHEHSH
CHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]