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The map label for this gene is moeA [H]

Identifier: 213158396

GI number: 213158396

Start: 2424429

End: 2425268

Strand: Reverse

Name: moeA [H]

Synonym: AB57_2344

Alternate gene names: 213158396

Gene position: 2425268-2424429 (Counterclockwise)

Preceding gene: 213158397

Following gene: 213158395

Centisome position: 59.88

GC content: 40.71

Gene sequence:

>840_bases
ATGTCAGGTTGTGGTGCTGAGCGTGGATTAATCAGTATAGATGAAGCGCTAGATTTAGTTATTAATAAGCCTAAAAACTT
AAGCTCTATTCAAAAGACTCTAACAAATAGCCTAAGTAGTTATCTTGCCAAAGAGATTTACTCTGAAATTAATCTACCTA
GCTTTTCTCAAAGTGCGGTAGACGGTTATGCACTTTGTAGCCATACAGAAGATTTAAATAATCAAAAGTTCCAAGTCACA
GGTGAGATTCGTGCCGGAAGCGAGAGTCATGACATACTCGGTGAAGGTCAGGCGATTCGTATATTTACGGGCGGCAAAAT
TCCTGAAGGGACAACGCATGTAGCACGGCAAGAAATCGTATCGGTTATTTCGGCCCAAGAAATTTGTTTAACGGAACATA
TACGCCCTCAAGCCGATATCCGCTTTACCGGAGAAGAAATCCAGCAAGGGCAGTTACTTGCTCAAGTAGGACAACTTTTG
AATATTGGAAGTTTAGCTGCTTTAAGTATGGCGGGTGTGCAAACCGTTGAAGTCTATCGTATACCGAAAGTCGCTGTTTT
AATCACGGGTGATGAAGTTGCTCAAACGGCAAAAGATTTAATCGATGGAAAAGTCTTTGATGCAAATGGTCCATTACTAA
AAGCTTGGTTTGAAGATTATGGTTTAGATGTTGAACTCATTCATGTGGCAGATGAAGCAGATCAGGTCACCCATTACTTT
AACCAACTAAAAGACAGCTATGATGTTGTTATAACGACTGGCGGAGTTTCGGTAGGAGACTACGACTTTGTTCGGCCCTG
TGCTTTCGAAGTGGATTTGAACAAATCTTTTGAAAGTTAA

Upstream 100 bases:

>100_bases
GCCGTGGTGGAGCAAGCGAATCAATGGCCGCTATTTTACCCGCATTAGTCCATATTTTTGATGTTTGCCGTGATTTACCG
CATCCAGGAGGCTATGAATA

Downstream 100 bases:

>100_bases
ACAAAAACGGGTAAACCTTTATTCTTTGCCGAATACCATAATTCACAAGCTATCCATTCTTGCTATTTGCTAGGTTTGCC
GGGCAATCCGGCTGCGGTAT

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSGCGAERGLISIDEALDLVINKPKNLSSIQKTLTNSLSSYLAKEIYSEINLPSFSQSAVDGYALCSHTEDLNNQKFQVT
GEIRAGSESHDILGEGQAIRIFTGGKIPEGTTHVARQEIVSVISAQEICLTEHIRPQADIRFTGEEIQQGQLLAQVGQLL
NIGSLAALSMAGVQTVEVYRIPKVAVLITGDEVAQTAKDLIDGKVFDANGPLLKAWFEDYGLDVELIHVADEADQVTHYF
NQLKDSYDVVITTGGVSVGDYDFVRPCAFEVDLNKSFES

Sequences:

>Translated_279_residues
MSGCGAERGLISIDEALDLVINKPKNLSSIQKTLTNSLSSYLAKEIYSEINLPSFSQSAVDGYALCSHTEDLNNQKFQVT
GEIRAGSESHDILGEGQAIRIFTGGKIPEGTTHVARQEIVSVISAQEICLTEHIRPQADIRFTGEEIQQGQLLAQVGQLL
NIGSLAALSMAGVQTVEVYRIPKVAVLITGDEVAQTAKDLIDGKVFDANGPLLKAWFEDYGLDVELIHVADEADQVTHYF
NQLKDSYDVVITTGGVSVGDYDFVRPCAFEVDLNKSFES
>Mature_278_residues
SGCGAERGLISIDEALDLVINKPKNLSSIQKTLTNSLSSYLAKEIYSEINLPSFSQSAVDGYALCSHTEDLNNQKFQVTG
EIRAGSESHDILGEGQAIRIFTGGKIPEGTTHVARQEIVSVISAQEICLTEHIRPQADIRFTGEEIQQGQLLAQVGQLLN
IGSLAALSMAGVQTVEVYRIPKVAVLITGDEVAQTAKDLIDGKVFDANGPLLKAWFEDYGLDVELIHVADEADQVTHYFN
QLKDSYDVVITTGGVSVGDYDFVRPCAFEVDLNKSFES

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=273, Percent_Identity=30.7692307692308, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI10880983, Length=273, Percent_Identity=30.7692307692308, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1787049, Length=260, Percent_Identity=31.5384615384615, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25147659, Length=262, Percent_Identity=27.0992366412214, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562606, Length=226, Percent_Identity=26.9911504424779, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136978, Length=265, Percent_Identity=26.0377358490566, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638841, Length=265, Percent_Identity=26.0377358490566, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 30297; Mature: 30166

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGCGAERGLISIDEALDLVINKPKNLSSIQKTLTNSLSSYLAKEIYSEINLPSFSQSAV
CCCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
DGYALCSHTEDLNNQKFQVTGEIRAGSESHDILGEGQAIRIFTGGKIPEGTTHVARQEIV
CHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
SVISAQEICLTEHIRPQADIRFTGEEIQQGQLLAQVGQLLNIGSLAALSMAGVQTVEVYR
HHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEE
IPKVAVLITGDEVAQTAKDLIDGKVFDANGPLLKAWFEDYGLDVELIHVADEADQVTHYF
CCEEEEEEECHHHHHHHHHHHCCEEECCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHH
NQLKDSYDVVITTGGVSVGDYDFVRPCAFEVDLNKSFES
HHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SGCGAERGLISIDEALDLVINKPKNLSSIQKTLTNSLSSYLAKEIYSEINLPSFSQSAV
CCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
DGYALCSHTEDLNNQKFQVTGEIRAGSESHDILGEGQAIRIFTGGKIPEGTTHVARQEIV
CHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
SVISAQEICLTEHIRPQADIRFTGEEIQQGQLLAQVGQLLNIGSLAALSMAGVQTVEVYR
HHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEE
IPKVAVLITGDEVAQTAKDLIDGKVFDANGPLLKAWFEDYGLDVELIHVADEADQVTHYF
CCEEEEEEECHHHHHHHHHHHCCEEECCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHH
NQLKDSYDVVITTGGVSVGDYDFVRPCAFEVDLNKSFES
HHHCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA