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The map label for this gene is glpD [H]

Identifier: 213158356

GI number: 213158356

Start: 3192326

End: 3193843

Strand: Reverse

Name: glpD [H]

Synonym: AB57_3086

Alternate gene names: 213158356

Gene position: 3193843-3192326 (Counterclockwise)

Preceding gene: 213158357

Following gene: 213158354

Centisome position: 78.85

GC content: 39.66

Gene sequence:

>1518_bases
ATGAAAGTACAACCTAATGATTATTCAAAAATATATGATATTGCTGTAATTGGTGGCGGTATTAATGGTGTTGGTATTGC
CAATGATGCAGCAGGGCGCGGATTATCGGTATTTTTATGTGAAAAAGATGATTTAGCCAGCCATACCTCATCTGCTAGCA
GCAAATTAATTCATGGCGGCCTACGTTATTTAGAACATAAAGAATTCAGGCTGGTCAGAGAAGCATTAGCAGAGCGTGAA
GTATTGCTAGCTAAAGCGCCACATATTATTAAACCAATGCGTTTTATCATGCCTCATCGACCCCATTTACGCCCTGCATG
GCTAATTCGAGCAGGTCTATTTTTTTATGATCATTTGGGAAAACGAGAAAAATTATTAGGTTCAAATCTTATTTATTTCA
AAGAAGACAGCCCGTTAAAACCAGCGATAACACGTGGTTTTGAATATTCTGACTGTACTGTAGATGATGCGCGTCTTGTG
GTGTTAAATGCACTACAAGCTAAAGAGAAAGGGGCAAAAGTCGTTACACGTACACGTTGTGTTAAGGCTTATAGGCAACA
GGAATTATGGCATCTGGAGTTACAAAGCGGAGCTGAGTTTTATCAGGTTCGTGCGAAAGCTATTGTAAATGCGGCGGGAC
CTTGGGTTGAAGAAATTATTAGTGAAAACCTGAACTTAAGTTCACCTTATCAAATTAGGCTTATACAAGGAAGTCATATT
GTTGTGCCAAAATTATATGACTGCCATAAGGCCTTTATTATGCAAAACGAAGATCGACGGATCGTTTTTGCAATTCCTTA
TTTAGAAAAATATACCCTCATTGGTACAACAGATCAGGAATACACAGGTGACCCACAAAAAGTAGAGATTACTGATGTGG
AAATTGATTACCTTTTGACAGTGACAAATTCACATTTTAAAAAGCAGTTGACGCGAGCTGATATTGTAAGTCAGTACTCG
GGTGTGCGTGCTTTATGTGATGATGAGTCGGATAATCCATCTGCAATTACACGCGACTATACTTTGGCTCTACAGGCAGA
AGATAAAACCACACCATTGCTTTCAGTGTTTGGGGGCAAGATTACAACTTACCGAAAGTTAGCCGAGGCTGCTTTAGAGC
ATCTGGCTCCGTTTTTTAATGACATGGCAGAGGAGTGGACTGCAGATGAGCCATTACCTGGCGCCGAAAACTGGACCACA
CTAGAGGGTTTAATCAATCAGATTAAAACACGTATAAGTGGAATTTCTGACTCACTTGCCAACCGTTGGGCTCATGCATA
TGGCACAAGAGTGTGGAATATGCTTAAAGAGCGAAATGCTATAGAACAATTGGGTCAACATTTTGGCCATGATTTGTTTG
AGTGTGAAGTCAGATATTTGTGTGAATATGAATGGGCTCACACAGCAGAAGATATACTTTGGCGCAGATCTAAATTAGGT
TTGGCATTTGATGAAAAACAGGTAAAAGTTTTAGAAGCTTATTTATCAGAACGTCGATTAAAAGATGATGCCGCATAA

Upstream 100 bases:

>100_bases
GCTAGAGGATGCAAAATTGATTATTCTACTTTTTTGATTGTTGTTTCATCAATTTGATGTTTTAATTTTTATAAGATCAA
CAATAAAAAGAACATGAGAA

Downstream 100 bases:

>100_bases
TAAAAAAGGTCGCACATGGCGACCTTTTTTATATAGAGCAATTAGAAGCCAGTTTTTACAGCTTCAAGTAAAGCTGCTTG
ACGTTCTTTTAATGCCTTAG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MKVQPNDYSKIYDIAVIGGGINGVGIANDAAGRGLSVFLCEKDDLASHTSSASSKLIHGGLRYLEHKEFRLVREALAERE
VLLAKAPHIIKPMRFIMPHRPHLRPAWLIRAGLFFYDHLGKREKLLGSNLIYFKEDSPLKPAITRGFEYSDCTVDDARLV
VLNALQAKEKGAKVVTRTRCVKAYRQQELWHLELQSGAEFYQVRAKAIVNAAGPWVEEIISENLNLSSPYQIRLIQGSHI
VVPKLYDCHKAFIMQNEDRRIVFAIPYLEKYTLIGTTDQEYTGDPQKVEITDVEIDYLLTVTNSHFKKQLTRADIVSQYS
GVRALCDDESDNPSAITRDYTLALQAEDKTTPLLSVFGGKITTYRKLAEAALEHLAPFFNDMAEEWTADEPLPGAENWTT
LEGLINQIKTRISGISDSLANRWAHAYGTRVWNMLKERNAIEQLGQHFGHDLFECEVRYLCEYEWAHTAEDILWRRSKLG
LAFDEKQVKVLEAYLSERRLKDDAA

Sequences:

>Translated_505_residues
MKVQPNDYSKIYDIAVIGGGINGVGIANDAAGRGLSVFLCEKDDLASHTSSASSKLIHGGLRYLEHKEFRLVREALAERE
VLLAKAPHIIKPMRFIMPHRPHLRPAWLIRAGLFFYDHLGKREKLLGSNLIYFKEDSPLKPAITRGFEYSDCTVDDARLV
VLNALQAKEKGAKVVTRTRCVKAYRQQELWHLELQSGAEFYQVRAKAIVNAAGPWVEEIISENLNLSSPYQIRLIQGSHI
VVPKLYDCHKAFIMQNEDRRIVFAIPYLEKYTLIGTTDQEYTGDPQKVEITDVEIDYLLTVTNSHFKKQLTRADIVSQYS
GVRALCDDESDNPSAITRDYTLALQAEDKTTPLLSVFGGKITTYRKLAEAALEHLAPFFNDMAEEWTADEPLPGAENWTT
LEGLINQIKTRISGISDSLANRWAHAYGTRVWNMLKERNAIEQLGQHFGHDLFECEVRYLCEYEWAHTAEDILWRRSKLG
LAFDEKQVKVLEAYLSERRLKDDAA
>Mature_505_residues
MKVQPNDYSKIYDIAVIGGGINGVGIANDAAGRGLSVFLCEKDDLASHTSSASSKLIHGGLRYLEHKEFRLVREALAERE
VLLAKAPHIIKPMRFIMPHRPHLRPAWLIRAGLFFYDHLGKREKLLGSNLIYFKEDSPLKPAITRGFEYSDCTVDDARLV
VLNALQAKEKGAKVVTRTRCVKAYRQQELWHLELQSGAEFYQVRAKAIVNAAGPWVEEIISENLNLSSPYQIRLIQGSHI
VVPKLYDCHKAFIMQNEDRRIVFAIPYLEKYTLIGTTDQEYTGDPQKVEITDVEIDYLLTVTNSHFKKQLTRADIVSQYS
GVRALCDDESDNPSAITRDYTLALQAEDKTTPLLSVFGGKITTYRKLAEAALEHLAPFFNDMAEEWTADEPLPGAENWTT
LEGLINQIKTRISGISDSLANRWAHAYGTRVWNMLKERNAIEQLGQHFGHDLFECEVRYLCEYEWAHTAEDILWRRSKLG
LAFDEKQVKVLEAYLSERRLKDDAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=510, Percent_Identity=29.6078431372549, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI285002231, Length=510, Percent_Identity=29.6078431372549, Blast_Score=162, Evalue=7e-40,
Organism=Escherichia coli, GI2367226, Length=465, Percent_Identity=54.1935483870968, Blast_Score=516, Evalue=1e-148,
Organism=Escherichia coli, GI1788574, Length=385, Percent_Identity=28.3116883116883, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534726, Length=509, Percent_Identity=30.6483300589391, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17509253, Length=509, Percent_Identity=29.4695481335953, Blast_Score=154, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6322036, Length=535, Percent_Identity=28.785046728972, Blast_Score=152, Evalue=9e-38,
Organism=Drosophila melanogaster, GI161077125, Length=512, Percent_Identity=28.90625, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24653942, Length=512, Percent_Identity=28.90625, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24653944, Length=512, Percent_Identity=28.90625, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI20130025, Length=512, Percent_Identity=28.90625, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24586295, Length=516, Percent_Identity=27.5193798449612, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19921278, Length=491, Percent_Identity=23.4215885947047, Blast_Score=105, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57430; Mature: 57430

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVQPNDYSKIYDIAVIGGGINGVGIANDAAGRGLSVFLCEKDDLASHTSSASSKLIHGG
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCHHHHHHHHHH
LRYLEHKEFRLVREALAEREVLLAKAPHIIKPMRFIMPHRPHLRPAWLIRAGLFFYDHLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KREKLLGSNLIYFKEDSPLKPAITRGFEYSDCTVDDARLVVLNALQAKEKGAKVVTRTRC
CHHHHHCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHHHHHHH
VKAYRQQELWHLELQSGAEFYQVRAKAIVNAAGPWVEEIISENLNLSSPYQIRLIQGSHI
HHHHHHHHHEEEEHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEECCEE
VVPKLYDCHKAFIMQNEDRRIVFAIPYLEKYTLIGTTDQEYTGDPQKVEITDVEIDYLLT
EECCHHHHHHHHHEECCCCEEEEEECCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEE
VTNSHFKKQLTRADIVSQYSGVRALCDDESDNPSAITRDYTLALQAEDKTTPLLSVFGGK
ECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHCCC
ITTYRKLAEAALEHLAPFFNDMAEEWTADEPLPGAENWTTLEGLINQIKTRISGISDSLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRWAHAYGTRVWNMLKERNAIEQLGQHFGHDLFECEVRYLCEYEWAHTAEDILWRRSKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHHHCC
LAFDEKQVKVLEAYLSERRLKDDAA
CEECHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKVQPNDYSKIYDIAVIGGGINGVGIANDAAGRGLSVFLCEKDDLASHTSSASSKLIHGG
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCHHHHHHHHHH
LRYLEHKEFRLVREALAEREVLLAKAPHIIKPMRFIMPHRPHLRPAWLIRAGLFFYDHLG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
KREKLLGSNLIYFKEDSPLKPAITRGFEYSDCTVDDARLVVLNALQAKEKGAKVVTRTRC
CHHHHHCCCEEEECCCCCCCHHHHCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHHHHHHH
VKAYRQQELWHLELQSGAEFYQVRAKAIVNAAGPWVEEIISENLNLSSPYQIRLIQGSHI
HHHHHHHHHEEEEHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEECCEE
VVPKLYDCHKAFIMQNEDRRIVFAIPYLEKYTLIGTTDQEYTGDPQKVEITDVEIDYLLT
EECCHHHHHHHHHEECCCCEEEEEECCCEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEE
VTNSHFKKQLTRADIVSQYSGVRALCDDESDNPSAITRDYTLALQAEDKTTPLLSVFGGK
ECCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHCCC
ITTYRKLAEAALEHLAPFFNDMAEEWTADEPLPGAENWTTLEGLINQIKTRISGISDSLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRWAHAYGTRVWNMLKERNAIEQLGQHFGHDLFECEVRYLCEYEWAHTAEDILWRRSKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHHHCC
LAFDEKQVKVLEAYLSERRLKDDAA
CEECHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]