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The map label for this gene is xdhA [H]

Identifier: 213158082

GI number: 213158082

Start: 2870829

End: 2872328

Strand: Reverse

Name: xdhA [H]

Synonym: AB57_2794

Alternate gene names: 213158082

Gene position: 2872328-2870829 (Counterclockwise)

Preceding gene: 213158085

Following gene: 213158081

Centisome position: 70.91

GC content: 40.67

Gene sequence:

>1500_bases
ATGTTAGAACGTCCAATCACCTTCTTTTTCCGTGGTGGTCAGCAGCTAGTAGAAAATGTAGTACCTACAATGACGGTTTT
ACAATTTCTGCGAGAATATACTCAAACTGGTAAGACTAGGCAGACTGGTACAAAAGAGGGATGTGCTGAGGGCGATTGTG
GTGCATGTACAGTAGTGATTGGTGAGTTGGTCAATGACAACCTGCAATTACGTAGTGTGAATGCGTGTATTCAGTTTTTA
CCGACTTTAGATGGTAAAGCCTTATTTACAGTAGAAGACCTTCATAGCTTATTGCCTGTACAAGATGGCACACTTCATCC
TGTACAACAGGCGATGGTCGATATGCATGGTTCACAATGCGGTTTTTGTACACCCGGTTTTATCATGTCGTTATGGTCAA
TGTACGAAAATGAACAACATTCTCCAAGCAAAGATAAAATCAGTGATTATCTTTCTGGAAACTTATGTCGCTGTACAGGC
TATCGCCCTATTTTAGATGCAGCACAAAAAGCTTATGACTATCCACGTGTGGTATTACAACGTCAAAAAGTAATTGATGT
ATTAAAAGAGATCAAAGCATTACCTGCATTGCATTTGAATGATCAAAAGCAGCAATTTTTTGCACCCAAAACTTTGCAGG
ATTTTGCTACTTTACGTTTACAGTTGCCGCAAGCACGTATTGTTGCAGGTAGCACAGATGTAGGTTTGTGGGTAACAAAG
CAGGGCCGTGATTTGGGCGATATGCTTTATATAGGTCAAGTTGAAGAGCTGAAAAAGATTGTAGTCACAGACCATGCTTT
AACGATTGGGGCAAATGTAAGTTTGAGCGATGCACTCATTAAAATTTCAGATTTTTATCCCGATTTTCAAGAATTACAGC
GCCGTTTTGCTTCCATGCCGATTAAAAATGCAGGAACACTAGGTGGAAATATTGCCAATGGTTCGCCTATTGGTGATTCA
ATGCCGGCATTAATTACGCTAGGTACACGATTGATTTTGCGCGTAGGTGAGCAGACCCGTGAAATTGCTTTGGAAGACTT
TTATTTAGACTATCAAAAAACAGCATTACAGCTTGGTGAGTTTGTTGAGGCGATTGTTATTCCGCTTCGTGAAGGGCAGA
CACGTTTTAAATTTGCCAGCTATAAAATTGCCAAACGATTTGAGCAAGATATTTCTGCGGTATGTGCAGCTATTTCTTGT
GAGTTAGATAATGATGATGTCACTTACAATGTAAGAATTGCTTTTGGTGGTATGGCAGCTATTCCCAAACGTGCAAAAAA
TGCAGAAGCCATATTAGAAGGCCAGCAAATTACAGCAGAATTGATCGTTCAGGCGCAGCAGGCATTGTCGCAAGACTATC
AGCCTTTAGATGATGGACGTGCTAGCTCGGCATATCGTTTACACGTCGCGAAAAACTGTTTACAGCGTTTTTATGTAGAA
AAAATCCTGTCTCAAACGATCACTCGTGTGAATGACTTGATCGCTATGGTGGAGATCTAA

Upstream 100 bases:

>100_bases
TTGGACATGAAATGTGCGCTTAATATTGATAAGTTCTAAATGATCGCCTAATGGCATCATATTTGCACAGAAGCATTATT
ATAAAGCATAAGGATAAAAC

Downstream 100 bases:

>100_bases
AATGAATCAAACCATTGACCTAAATATTTCTAAAAAATCAGCTAAAGCAGGCGACTCGATTCCACACGAAAGTGCACATT
TACATGTGACCGGGCAGGCA

Product: xanthine dehydrogenase, small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MLERPITFFFRGGQQLVENVVPTMTVLQFLREYTQTGKTRQTGTKEGCAEGDCGACTVVIGELVNDNLQLRSVNACIQFL
PTLDGKALFTVEDLHSLLPVQDGTLHPVQQAMVDMHGSQCGFCTPGFIMSLWSMYENEQHSPSKDKISDYLSGNLCRCTG
YRPILDAAQKAYDYPRVVLQRQKVIDVLKEIKALPALHLNDQKQQFFAPKTLQDFATLRLQLPQARIVAGSTDVGLWVTK
QGRDLGDMLYIGQVEELKKIVVTDHALTIGANVSLSDALIKISDFYPDFQELQRRFASMPIKNAGTLGGNIANGSPIGDS
MPALITLGTRLILRVGEQTREIALEDFYLDYQKTALQLGEFVEAIVIPLREGQTRFKFASYKIAKRFEQDISAVCAAISC
ELDNDDVTYNVRIAFGGMAAIPKRAKNAEAILEGQQITAELIVQAQQALSQDYQPLDDGRASSAYRLHVAKNCLQRFYVE
KILSQTITRVNDLIAMVEI

Sequences:

>Translated_499_residues
MLERPITFFFRGGQQLVENVVPTMTVLQFLREYTQTGKTRQTGTKEGCAEGDCGACTVVIGELVNDNLQLRSVNACIQFL
PTLDGKALFTVEDLHSLLPVQDGTLHPVQQAMVDMHGSQCGFCTPGFIMSLWSMYENEQHSPSKDKISDYLSGNLCRCTG
YRPILDAAQKAYDYPRVVLQRQKVIDVLKEIKALPALHLNDQKQQFFAPKTLQDFATLRLQLPQARIVAGSTDVGLWVTK
QGRDLGDMLYIGQVEELKKIVVTDHALTIGANVSLSDALIKISDFYPDFQELQRRFASMPIKNAGTLGGNIANGSPIGDS
MPALITLGTRLILRVGEQTREIALEDFYLDYQKTALQLGEFVEAIVIPLREGQTRFKFASYKIAKRFEQDISAVCAAISC
ELDNDDVTYNVRIAFGGMAAIPKRAKNAEAILEGQQITAELIVQAQQALSQDYQPLDDGRASSAYRLHVAKNCLQRFYVE
KILSQTITRVNDLIAMVEI
>Mature_499_residues
MLERPITFFFRGGQQLVENVVPTMTVLQFLREYTQTGKTRQTGTKEGCAEGDCGACTVVIGELVNDNLQLRSVNACIQFL
PTLDGKALFTVEDLHSLLPVQDGTLHPVQQAMVDMHGSQCGFCTPGFIMSLWSMYENEQHSPSKDKISDYLSGNLCRCTG
YRPILDAAQKAYDYPRVVLQRQKVIDVLKEIKALPALHLNDQKQQFFAPKTLQDFATLRLQLPQARIVAGSTDVGLWVTK
QGRDLGDMLYIGQVEELKKIVVTDHALTIGANVSLSDALIKISDFYPDFQELQRRFASMPIKNAGTLGGNIANGSPIGDS
MPALITLGTRLILRVGEQTREIALEDFYLDYQKTALQLGEFVEAIVIPLREGQTRFKFASYKIAKRFEQDISAVCAAISC
ELDNDDVTYNVRIAFGGMAAIPKRAKNAEAILEGQQITAELIVQAQQALSQDYQPLDDGRASSAYRLHVAKNCLQRFYVE
KILSQTITRVNDLIAMVEI

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=469, Percent_Identity=30.7036247334755, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI71773480, Length=496, Percent_Identity=28.2258064516129, Blast_Score=148, Evalue=9e-36,
Organism=Escherichia coli, GI1789231, Length=276, Percent_Identity=26.8115942028986, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786480, Length=181, Percent_Identity=35.3591160220994, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789232, Length=123, Percent_Identity=36.5853658536585, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=566, Percent_Identity=27.7385159010601, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI32566215, Length=487, Percent_Identity=27.1047227926078, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17539860, Length=484, Percent_Identity=26.2396694214876, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17737937, Length=507, Percent_Identity=30.1775147928994, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24647199, Length=494, Percent_Identity=29.1497975708502, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24647197, Length=492, Percent_Identity=29.2682926829268, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24647201, Length=514, Percent_Identity=27.6264591439689, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24647195, Length=318, Percent_Identity=33.0188679245283, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24647193, Length=502, Percent_Identity=28.4860557768924, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR017606
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 55487; Mature: 55487

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERPITFFFRGGQQLVENVVPTMTVLQFLREYTQTGKTRQTGTKEGCAEGDCGACTVVI
CCCCCEEHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
GELVNDNLQLRSVNACIQFLPTLDGKALFTVEDLHSLLPVQDGTLHPVQQAMVDMHGSQC
HHHHCCCCEEEHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
GFCTPGFIMSLWSMYENEQHSPSKDKISDYLSGNLCRCTGYRPILDAAQKAYDYPRVVLQ
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCHHHHHH
RQKVIDVLKEIKALPALHLNDQKQQFFAPKTLQDFATLRLQLPQARIVAGSTDVGLWVTK
HHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEEC
QGRDLGDMLYIGQVEELKKIVVTDHALTIGANVSLSDALIKISDFYPDFQELQRRFASMP
CCCCCCCEEECCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCC
IKNAGTLGGNIANGSPIGDSMPALITLGTRLILRVGEQTREIALEDFYLDYQKTALQLGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
FVEAIVIPLREGQTRFKFASYKIAKRFEQDISAVCAAISCELDNDDVTYNVRIAFGGMAA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEECCHHH
IPKRAKNAEAILEGQQITAELIVQAQQALSQDYQPLDDGRASSAYRLHVAKNCLQRFYVE
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHH
KILSQTITRVNDLIAMVEI
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLERPITFFFRGGQQLVENVVPTMTVLQFLREYTQTGKTRQTGTKEGCAEGDCGACTVVI
CCCCCEEHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
GELVNDNLQLRSVNACIQFLPTLDGKALFTVEDLHSLLPVQDGTLHPVQQAMVDMHGSQC
HHHHCCCCEEEHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
GFCTPGFIMSLWSMYENEQHSPSKDKISDYLSGNLCRCTGYRPILDAAQKAYDYPRVVLQ
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCHHHHHH
RQKVIDVLKEIKALPALHLNDQKQQFFAPKTLQDFATLRLQLPQARIVAGSTDVGLWVTK
HHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEEEC
QGRDLGDMLYIGQVEELKKIVVTDHALTIGANVSLSDALIKISDFYPDFQELQRRFASMP
CCCCCCCEEECCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCC
IKNAGTLGGNIANGSPIGDSMPALITLGTRLILRVGEQTREIALEDFYLDYQKTALQLGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
FVEAIVIPLREGQTRFKFASYKIAKRFEQDISAVCAAISCELDNDDVTYNVRIAFGGMAA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEEECCHHH
IPKRAKNAEAILEGQQITAELIVQAQQALSQDYQPLDDGRASSAYRLHVAKNCLQRFYVE
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHH
KILSQTITRVNDLIAMVEI
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]