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The map label for this gene is trpD [H]

Identifier: 213158077

GI number: 213158077

Start: 2864875

End: 2865930

Strand: Direct

Name: trpD [H]

Synonym: AB57_2789

Alternate gene names: 213158077

Gene position: 2864875-2865930 (Clockwise)

Preceding gene: 213158074

Following gene: 213158078

Centisome position: 70.73

GC content: 42.71

Gene sequence:

>1056_bases
ATGACTATGAATATCCAACAGGCGCTCAACCACATTACCAAGAACATTCATTTGACTCAGCCTCAAATGGAAGAAATTAT
GCGCAGCATCATGCAAGGTGAGGCAACCGAAGCACAAATTGGTGCTTTAATGATGGGCTTACGCATGAAAGGTGAAAGCA
TTGACGAAATGACAGCTGCTGCACGTGTCATGCGAGAATTTGCGATCAAAATCGATGTGAGCGATATCAAACATTTAGTG
GATATCGTGGGAACTGGCGGTGATGGACAAAATTTATTTAACGTTTCTACAGCGTCTAGCTTTGTGATTGCTGCAGCAGG
TGCGACCATTGCAAAACATGGTAATCGTGGCGTTTCAAGTAAATCAGGTTCATCAGACCTACTTGAACAAGCAGGTATTC
ATCTTGATTTAGATATGCAACAAACCGAACGCTGCATCCGTGAAATGGGTGTGGGTTTCTTGTTTGCACCAAACCACCAC
AAAGCCATGAAATATGCTGCTGGCCCACGTCGTGAACTTGGTATTCGTAGTATTTTTAATTTACTCGGTCCACTGACCAA
CCCGGCTGGGGTAAAGCGCTTTGTCATTGGTGTGTTCTCAGATGAACTTTGTCGCCCGATTGCCGAAGTGATGAAACAAC
TTGGTGCCGAACATGTCATGGTTGTCCATTCAAAAGATGGTCTTGATGAAATCAGTCTTGCAGCTCCGACAACTATTGCT
GAGCTTAAAGACGGTGAAATTACGGAATGGACCCTTAATCCTGAAGATGTCGGGATTGAGTCACAAACATTAAATGGTTT
GGTTGTCGCAGATGCAACGGCGAGTCTAAAGCTCATTAAAGATGCTTTAAGCAAAAATAAATCTGATATTGGTGAAAAAG
CTGCAAACATGATTGCGCTTAATGCAGGCGCAGGCATTTATGTAGCAGGCATTACCAAGACTTATGCTCAGGCTGTTGCA
TTCGCTCAAGATATTATTTACGGCGGGCAAGCATTAGAGAAAATGAGTGTTTTAGCTGAATTTACTAAAACATTAAAACA
ATCTCAGGCAGATTAA

Upstream 100 bases:

>100_bases
ACATAGCTCCCCTAGCTAGTGAATCATGGAACGCAATAGGCCGAACCTCCCGCACTCGATCAACTTCACCTAAAAATTTT
AATCATTAATGCTGTAAATC

Downstream 100 bases:

>100_bases
GGACTTCTCATGATTAATATTCAAAATACCATTTTAGGTAAAATTGTTGACCGTAAACATGAGGAACTTGCTGCGCGTTT
AAAACAACGTAATTTGCAAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTMNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAAARVMREFAIKIDVSDIKHLV
DIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHH
KAMKYAAGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIA
ELKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIALNAGAGIYVAGITKTYAQAVA
FAQDIIYGGQALEKMSVLAEFTKTLKQSQAD

Sequences:

>Translated_351_residues
MTMNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAAARVMREFAIKIDVSDIKHLV
DIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHH
KAMKYAAGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIA
ELKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIALNAGAGIYVAGITKTYAQAVA
FAQDIIYGGQALEKMSVLAEFTKTLKQSQAD
>Mature_350_residues
TMNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAAARVMREFAIKIDVSDIKHLVD
IVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSSKSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHHK
AMKYAAGPRRELGIRSIFNLLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIAE
LKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIALNAGAGIYVAGITKTYAQAVAF
AQDIIYGGQALEKMSVLAEFTKTLKQSQAD

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=255, Percent_Identity=44.7058823529412, Blast_Score=204, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=271, Percent_Identity=29.520295202952, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37636; Mature: 37505

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAA
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
ARVMREFAIKIDVSDIKHLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSS
HHHHHHHHHEEEHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEECCCHHHHCCCCCCCC
KSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHHKAMKYAAGPRRELGIRSIFN
CCCCHHHHHHCCCEEEECHHHHHHHHHHHCCCEEECCCCHHHHHHCCCCCHHHHHHHHHH
LLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHH
ELKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIAL
HCCCCCEEEEECCHHHCCCCHHCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHEEEE
NAGAGIYVAGITKTYAQAVAFAQDIIYGGQALEKMSVLAEFTKTLKQSQAD
ECCCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TMNIQQALNHITKNIHLTQPQMEEIMRSIMQGEATEAQIGALMMGLRMKGESIDEMTAA
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
ARVMREFAIKIDVSDIKHLVDIVGTGGDGQNLFNVSTASSFVIAAAGATIAKHGNRGVSS
HHHHHHHHHEEEHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEECCCHHHHCCCCCCCC
KSGSSDLLEQAGIHLDLDMQQTERCIREMGVGFLFAPNHHKAMKYAAGPRRELGIRSIFN
CCCCHHHHHHCCCEEEECHHHHHHHHHHHCCCEEECCCCHHHHHHCCCCCHHHHHHHHHH
LLGPLTNPAGVKRFVIGVFSDELCRPIAEVMKQLGAEHVMVVHSKDGLDEISLAAPTTIA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHH
ELKDGEITEWTLNPEDVGIESQTLNGLVVADATASLKLIKDALSKNKSDIGEKAANMIAL
HCCCCCEEEEECCHHHCCCCHHCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHEEEE
NAGAGIYVAGITKTYAQAVAFAQDIIYGGQALEKMSVLAEFTKTLKQSQAD
ECCCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA