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The map label for this gene is yclF [H]

Identifier: 213158072

GI number: 213158072

Start: 2854694

End: 2856235

Strand: Direct

Name: yclF [H]

Synonym: AB57_2784

Alternate gene names: 213158072

Gene position: 2854694-2856235 (Clockwise)

Preceding gene: 213158066

Following gene: 213158073

Centisome position: 70.48

GC content: 38.59

Gene sequence:

>1542_bases
ATGAAATATGACTTTGAACAATCGGATAAAGCTTTTTTCGGCCATCCTAAACCATTACAAACGCTATTTTTTACAGAGCT
TTGGGAAAGATTTTCTTATTATGGAATCCGGCCCTTACTCGTTCTTTATATGATTGCGATGGTCAATGACGGCGGTCTAG
CACTTGATCGACCAACTGCCGCAGCGATTGTCGGATTATTTGCAGGCTCCATGTATTTAATGACCGTTTTTGGGGGGTGG
GTTGCCGATAACTGGTTAGGCCAAGCACGTGCTGTCTGGTACGGTTCAATTATTATTGCCTTAGGCCACTTATCAATTGC
CCTTACATCTGTATTTGATCAGTCTTTCTTTTACTTAGGTTTAGTACTGATTGTTTTAGGTACAGGGTTATTTAAAACAT
GTATTTCTGTGATTGTGGGAACACTATATAAAGCCAATGATTCAAGACGTGATGCAGGTTTTTCCATTTTCTATATGGGA
ATTAATATGGGGTCATTTATTGCCCCACTTATTACAGGGCTTTTGGCGAAAGACCATGGCTGGCATTTAGGTTTTGGTAT
TGGTGGCATTGGGATGTTAATTGCTTTATTAATTTTCCGTTTTATGGCAATGCCCCAGCTTCAAACTTTTAATGAGCTAC
GCCAAGAAGCCAATAGCTGTAGCAAACCTGTCGTAGAAAATAAAAATGCGCCTAAAATTGTATTTAGCTTTTTATTCGCA
GTTGCAGTCGTTATTGCGCTAACCTTCCTCGGTATCATTCACATCAATCCCGTGGCTGTCGCAACCTATTTAACCGTAGG
AATTAGCTTTGGGATTATTGCTTATTTTGCATATTTACTACTTTTCCTGAATTTAGAGCAACATGAAAAATTTAAAATAA
TTATTTGCTTCGTTTTATTAGCAGCCTCTGCCCTATTCTGGTCAGCTTTCGAACAAAAACCCACAACTTTTACTTTATTT
GCGCAAGATTATACGGACCGTATTGTTTTCGGATTTGAGATTCCCACTGTATGGTTTGAATCAATCAATGCTCTTTTTAT
TATTATCTTTGCTCCAGTTGCAGCTTGGCTATGGGCGAAACTAGGTAAAGCGAATAAAGATCCAAGCTATATCAGCAAAT
TTATTATTGCGTTGTTATTCGCCGCAGGTGGCTTTTTACTTATGTCTCTAGCCAGTCATTTTGCTATTCATGGCGGAGTA
GTTTCACCATTTTGGTTAGTCGGTACTTTATTTCTTCTTACCATAGGTGAACTTTGCTTAAGCCCAATTGGCTTATCAAC
CATGACCAAACTTGCACCTGATGTCATACGTAGTCAAATTATGGGTTTATGGTTTACAGGTACAGCTCTTGGCAACCTCA
TGGCAGGTTTAATTGGCGGGCAAGTCTCGGTAGATGGTATTAATCATTTACCTAGCCTATTTATGCGCTGTGTATTAGCC
TTGGTTATTGGCGCAATCGTGTTATTTTTATTAAAGAAACCAATGAATAAATTAATGGACAAAAGTACCAACAAAGTTCA
ACCTGATTTGGAAACGATATGA

Upstream 100 bases:

>100_bases
ATTAAAAAAACTAAAAACTATATGCATAAATTTTTGTTATAAATAAACAAACCAAAAGTTATGTTTATAAAAAACTTAAA
AGCATTCAAGGATTTGAATA

Downstream 100 bases:

>100_bases
ACGACTTAACTGTTCCAGAAAAACTAGCGAAACTTCGTGAACTCATGACCAATCAAAGTATTGATGCTTTGGTTGTCATG
AGTGCAGACCCCCATATGTC

Product: dipeptide/tripeptide permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKYDFEQSDKAFFGHPKPLQTLFFTELWERFSYYGIRPLLVLYMIAMVNDGGLALDRPTAAAIVGLFAGSMYLMTVFGGW
VADNWLGQARAVWYGSIIIALGHLSIALTSVFDQSFFYLGLVLIVLGTGLFKTCISVIVGTLYKANDSRRDAGFSIFYMG
INMGSFIAPLITGLLAKDHGWHLGFGIGGIGMLIALLIFRFMAMPQLQTFNELRQEANSCSKPVVENKNAPKIVFSFLFA
VAVVIALTFLGIIHINPVAVATYLTVGISFGIIAYFAYLLLFLNLEQHEKFKIIICFVLLAASALFWSAFEQKPTTFTLF
AQDYTDRIVFGFEIPTVWFESINALFIIIFAPVAAWLWAKLGKANKDPSYISKFIIALLFAAGGFLLMSLASHFAIHGGV
VSPFWLVGTLFLLTIGELCLSPIGLSTMTKLAPDVIRSQIMGLWFTGTALGNLMAGLIGGQVSVDGINHLPSLFMRCVLA
LVIGAIVLFLLKKPMNKLMDKSTNKVQPDLETI

Sequences:

>Translated_513_residues
MKYDFEQSDKAFFGHPKPLQTLFFTELWERFSYYGIRPLLVLYMIAMVNDGGLALDRPTAAAIVGLFAGSMYLMTVFGGW
VADNWLGQARAVWYGSIIIALGHLSIALTSVFDQSFFYLGLVLIVLGTGLFKTCISVIVGTLYKANDSRRDAGFSIFYMG
INMGSFIAPLITGLLAKDHGWHLGFGIGGIGMLIALLIFRFMAMPQLQTFNELRQEANSCSKPVVENKNAPKIVFSFLFA
VAVVIALTFLGIIHINPVAVATYLTVGISFGIIAYFAYLLLFLNLEQHEKFKIIICFVLLAASALFWSAFEQKPTTFTLF
AQDYTDRIVFGFEIPTVWFESINALFIIIFAPVAAWLWAKLGKANKDPSYISKFIIALLFAAGGFLLMSLASHFAIHGGV
VSPFWLVGTLFLLTIGELCLSPIGLSTMTKLAPDVIRSQIMGLWFTGTALGNLMAGLIGGQVSVDGINHLPSLFMRCVLA
LVIGAIVLFLLKKPMNKLMDKSTNKVQPDLETI
>Mature_513_residues
MKYDFEQSDKAFFGHPKPLQTLFFTELWERFSYYGIRPLLVLYMIAMVNDGGLALDRPTAAAIVGLFAGSMYLMTVFGGW
VADNWLGQARAVWYGSIIIALGHLSIALTSVFDQSFFYLGLVLIVLGTGLFKTCISVIVGTLYKANDSRRDAGFSIFYMG
INMGSFIAPLITGLLAKDHGWHLGFGIGGIGMLIALLIFRFMAMPQLQTFNELRQEANSCSKPVVENKNAPKIVFSFLFA
VAVVIALTFLGIIHINPVAVATYLTVGISFGIIAYFAYLLLFLNLEQHEKFKIIICFVLLAASALFWSAFEQKPTTFTLF
AQDYTDRIVFGFEIPTVWFESINALFIIIFAPVAAWLWAKLGKANKDPSYISKFIIALLFAAGGFLLMSLASHFAIHGGV
VSPFWLVGTLFLLTIGELCLSPIGLSTMTKLAPDVIRSQIMGLWFTGTALGNLMAGLIGGQVSVDGINHLPSLFMRCVLA
LVIGAIVLFLLKKPMNKLMDKSTNKVQPDLETI

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=214, Percent_Identity=30.8411214953271, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226371746, Length=202, Percent_Identity=33.1683168316832, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI226371748, Length=195, Percent_Identity=31.2820512820513, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1787922, Length=453, Percent_Identity=30.4635761589404, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1790572, Length=506, Percent_Identity=29.2490118577075, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1786927, Length=455, Percent_Identity=28.1318681318681, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789911, Length=497, Percent_Identity=27.5653923541247, Blast_Score=186, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17569141, Length=197, Percent_Identity=30.9644670050761, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71987453, Length=180, Percent_Identity=30.5555555555556, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17541704, Length=365, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI28571102, Length=201, Percent_Identity=32.3383084577114, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571100, Length=201, Percent_Identity=32.3383084577114, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571098, Length=201, Percent_Identity=31.8407960199005, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24639581, Length=370, Percent_Identity=26.7567567567568, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639583, Length=358, Percent_Identity=26.8156424581006, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24639585, Length=358, Percent_Identity=26.8156424581006, Blast_Score=97, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56466; Mature: 56466

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]