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The map label for this gene is ubiA [H]

Identifier: 213158069

GI number: 213158069

Start: 2851035

End: 2851913

Strand: Reverse

Name: ubiA [H]

Synonym: AB57_2781

Alternate gene names: 213158069

Gene position: 2851913-2851035 (Counterclockwise)

Preceding gene: 213158070

Following gene: 213158068

Centisome position: 70.41

GC content: 38.0

Gene sequence:

>879_bases
ATGACGACTGCAACAGGTACAACATGGCGTCAGCGTTTAGAAGCTTATTATTATCTATGCCGATTTGATAAGCCAATTGG
TACTGAACTGGTGTTTTGGCCAACCATGTGGGCACTTTGGGTTGCATCAAAAGGAATACCGAATTTGGGTATTTTATTCG
TCATGATTTTAGGCGTCATTTTTATGCGCGCTGCTGGATGTGCCATTAATGACTTTGCTGATCGTAAAGTAGATGGTCAT
GTAGAGCGTACAAAAACACGTCCTTTAGCAACAGGGGTTATTCGAGCAAGAGAAGCAGTATATGTATTCTTGGGTCTTGT
TTTAGCAAGTGCATGTTTGTTGTTCTTTTTACCCATAGAAACTTTCTACTGGTCATTTGGAGCATTATTTTTAGCTTTCA
TTTATCCATTTATGAAACGCTATACCAACTTACCGCAAGTTTTTTTAGGAGCAGCATTTTCATGGTCAATTCCAATGGCC
TTTACTGCGGTAGGTAAAACTCCGGATCTGACTTGCTGGCTGCTGTATTTTGGTAATTTGGCTTGGACAGTGGCTTATGA
CACTCAATATGCAATTACAGACCGTGAGTATGATTTAAAGATTGGTGTGAAATCTACCGCTATTCTTTTTGGTCGATATG
ACATCCAGATTATTGCGCTTTTACAAGCAATAAGTCTTGTTTTGATTGGTACAGCGCTATATTTAGAAAATATCTTATTT
CCTTGGGCCATTATTGCTTTAGTTGTAGTGGCATTTGATTTTGTATATCAAACAATTAAAACCAAAGACCGCAACCCTCA
GGTATGTTTTTGGGCATTCCGTCACAATCGTTGGGTTGGATTAATCATTTTTCTAGGAATATTTTTAAATTTCATATAG

Upstream 100 bases:

>100_bases
AAAGTTGCTATACTTGGCATGGATGTAAATTTATTGTTCAAGAAACATTCTTACCGGCTTTTGAAGCTTTTTTATATCAG
CAGCACGACAAGGAATTACT

Downstream 100 bases:

>100_bases
TAAAAATGACCGTGAGGTTGAAAAGTGTTCTATGCAGAGCACTTTTTTTATGTCTTAATATTTGTGCATGAAAAATATGC
GGAATAAATAACACATAAAA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTTATGTTWRQRLEAYYYLCRFDKPIGTELVFWPTMWALWVASKGIPNLGILFVMILGVIFMRAAGCAINDFADRKVDGH
VERTKTRPLATGVIRAREAVYVFLGLVLASACLLFFLPIETFYWSFGALFLAFIYPFMKRYTNLPQVFLGAAFSWSIPMA
FTAVGKTPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFGRYDIQIIALLQAISLVLIGTALYLENILF
PWAIIALVVVAFDFVYQTIKTKDRNPQVCFWAFRHNRWVGLIIFLGIFLNFI

Sequences:

>Translated_292_residues
MTTATGTTWRQRLEAYYYLCRFDKPIGTELVFWPTMWALWVASKGIPNLGILFVMILGVIFMRAAGCAINDFADRKVDGH
VERTKTRPLATGVIRAREAVYVFLGLVLASACLLFFLPIETFYWSFGALFLAFIYPFMKRYTNLPQVFLGAAFSWSIPMA
FTAVGKTPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFGRYDIQIIALLQAISLVLIGTALYLENILF
PWAIIALVVVAFDFVYQTIKTKDRNPQVCFWAFRHNRWVGLIIFLGIFLNFI
>Mature_291_residues
TTATGTTWRQRLEAYYYLCRFDKPIGTELVFWPTMWALWVASKGIPNLGILFVMILGVIFMRAAGCAINDFADRKVDGHV
ERTKTRPLATGVIRAREAVYVFLGLVLASACLLFFLPIETFYWSFGALFLAFIYPFMKRYTNLPQVFLGAAFSWSIPMAF
TAVGKTPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFGRYDIQIIALLQAISLVLIGTALYLENILFP
WAIIALVVVAFDFVYQTIKTKDRNPQVCFWAFRHNRWVGLIIFLGIFLNFI

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=290, Percent_Identity=36.8965517241379, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=51.4084507042254, Blast_Score=273, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI32565247, Length=279, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17553718, Length=279, Percent_Identity=32.6164874551971, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17553720, Length=336, Percent_Identity=28.2738095238095, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=38.2978723404255, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=37.8571428571429, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324370, Length=284, Percent_Identity=33.8028169014084, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355567, Length=281, Percent_Identity=38.0782918149466, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33405; Mature: 33274

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTATGTTWRQRLEAYYYLCRFDKPIGTELVFWPTMWALWVASKGIPNLGILFVMILGVI
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FMRAAGCAINDFADRKVDGHVERTKTRPLATGVIRAREAVYVFLGLVLASACLLFFLPIE
HHHHCCCCHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFYWSFGALFLAFIYPFMKRYTNLPQVFLGAAFSWSIPMAFTAVGKTPDLTCWLLYFGNL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHCCCCCHHEEECCCCCCCEEHEEECCCE
AWTVAYDTQYAITDREYDLKIGVKSTAILFGRYDIQIIALLQAISLVLIGTALYLENILF
EEEEEECCEEEEECCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PWAIIALVVVAFDFVYQTIKTKDRNPQVCFWAFRHNRWVGLIIFLGIFLNFI
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTATGTTWRQRLEAYYYLCRFDKPIGTELVFWPTMWALWVASKGIPNLGILFVMILGVI
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FMRAAGCAINDFADRKVDGHVERTKTRPLATGVIRAREAVYVFLGLVLASACLLFFLPIE
HHHHCCCCHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFYWSFGALFLAFIYPFMKRYTNLPQVFLGAAFSWSIPMAFTAVGKTPDLTCWLLYFGNL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHCCCCCHHEEECCCCCCCEEHEEECCCE
AWTVAYDTQYAITDREYDLKIGVKSTAILFGRYDIQIIALLQAISLVLIGTALYLENILF
EEEEEECCEEEEECCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PWAIIALVVVAFDFVYQTIKTKDRNPQVCFWAFRHNRWVGLIIFLGIFLNFI
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA