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The map label for this gene is ubiC

Identifier: 213158070

GI number: 213158070

Start: 2851910

End: 2852419

Strand: Reverse

Name: ubiC

Synonym: AB57_2782

Alternate gene names: 213158070

Gene position: 2852419-2851910 (Counterclockwise)

Preceding gene: 213158071

Following gene: 213158069

Centisome position: 70.42

GC content: 40.0

Gene sequence:

>510_bases
ATGCGTAAACGACAACCAGTACTTAAGCAGGAAAAGACTTTAAATCCTGAATTGAAAACATGGTTGTATGCGTCTGGTTC
TCTGACACAACAACTCACTGAGCTGGGTGGTGGGAAGTTCAGCGTAAAGCCTTTCAAAGAACATTTCCAGCGTTTAACTT
TTGCCGACAGTCAATGGATGAACATGCCCCATACCCACACTTCTTGGGTAAGGGAAACCTATTTATATGGCAGTGATGTA
GAGCCGTGGGTGAAAGCAAAAAGTATTTTTCCCATTCAAAGTTTACAAAAAAAAGCCCGTATATTTCAGCATATTGGTTC
TAAGCCAATAGGTCTTTTTTTATTTCAAAGAACAACACCACTTTGTGATCGCCGGGTTATTCGTTTACCAGAAGGCTGGA
CGCGACAAAGTTGCTATACTTGGCATGGATGTAAATTTATTGTTCAAGAAACATTCTTACCGGCTTTTGAAGCTTTTTTA
TATCAGCAGCACGACAAGGAATTACTATGA

Upstream 100 bases:

>100_bases
TATGCAGGCTTTTTTATTGCTTGGAATGTTGATTGAATTCTCTACGTTTTTTATCAAAAAATTGGGGTAAACTAGGTGCG
AGTTTTCATGTGAGCAGATT

Downstream 100 bases:

>100_bases
CGACTGCAACAGGTACAACATGGCGTCAGCGTTTAGAAGCTTATTATTATCTATGCCGATTTGATAAGCCAATTGGTACT
GAACTGGTGTTTTGGCCAAC

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MRKRQPVLKQEKTLNPELKTWLYASGSLTQQLTELGGGKFSVKPFKEHFQRLTFADSQWMNMPHTHTSWVRETYLYGSDV
EPWVKAKSIFPIQSLQKKARIFQHIGSKPIGLFLFQRTTPLCDRRVIRLPEGWTRQSCYTWHGCKFIVQETFLPAFEAFL
YQQHDKELL

Sequences:

>Translated_169_residues
MRKRQPVLKQEKTLNPELKTWLYASGSLTQQLTELGGGKFSVKPFKEHFQRLTFADSQWMNMPHTHTSWVRETYLYGSDV
EPWVKAKSIFPIQSLQKKARIFQHIGSKPIGLFLFQRTTPLCDRRVIRLPEGWTRQSCYTWHGCKFIVQETFLPAFEAFL
YQQHDKELL
>Mature_169_residues
MRKRQPVLKQEKTLNPELKTWLYASGSLTQQLTELGGGKFSVKPFKEHFQRLTFADSQWMNMPHTHTSWVRETYLYGSDV
EPWVKAKSIFPIQSLQKKARIFQHIGSKPIGLFLFQRTTPLCDRRVIRLPEGWTRQSCYTWHGCKFIVQETFLPAFEAFL
YQQHDKELL

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=148, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_ACIBT (A3M775)

Other databases:

- EMBL:   CP000521
- RefSeq:   YP_001085371.1
- ProteinModelPortal:   A3M775
- SMR:   A3M775
- STRING:   A3M775
- GeneID:   4919894
- GenomeReviews:   CP000521_GR
- KEGG:   acb:A1S_2350
- eggNOG:   COG3161
- HOGENOM:   HBG289129
- ProtClustDB:   CLSK830668
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19992; Mature: 19992

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: BINDING 71-71 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRQPVLKQEKTLNPELKTWLYASGSLTQQLTELGGGKFSVKPFKEHFQRLTFADSQWM
CCCCCCCHHHHHCCCHHHHHHEECCCHHHHHHHHHCCCCEECCHHHHHHHHHHCCCHHHC
NMPHTHTSWVRETYLYGSDVEPWVKAKSIFPIQSLQKKARIFQHIGSKPIGLFLFQRTTP
CCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
LCDRRVIRLPEGWTRQSCYTWHGCKFIVQETFLPAFEAFLYQQHDKELL
CCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKRQPVLKQEKTLNPELKTWLYASGSLTQQLTELGGGKFSVKPFKEHFQRLTFADSQWM
CCCCCCCHHHHHCCCHHHHHHEECCCHHHHHHHHHCCCCEECCHHHHHHHHHHCCCHHHC
NMPHTHTSWVRETYLYGSDVEPWVKAKSIFPIQSLQKKARIFQHIGSKPIGLFLFQRTTP
CCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
LCDRRVIRLPEGWTRQSCYTWHGCKFIVQETFLPAFEAFLYQQHDKELL
CCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA