The gene/protein map for NC_011586 is currently unavailable.
Definition Acinetobacter baumannii AB0057, complete genome.
Accession NC_011586
Length 4,050,513

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The map label for this gene is cca

Identifier: 213158062

GI number: 213158062

Start: 2843897

End: 2845135

Strand: Direct

Name: cca

Synonym: AB57_2774

Alternate gene names: 213158062

Gene position: 2843897-2845135 (Clockwise)

Preceding gene: 213158061

Following gene: 213158064

Centisome position: 70.21

GC content: 41.97

Gene sequence:

>1239_bases
ATGCAAGTGTATTTAGTAGGCGGTGCTGTTCGAGATTATTTACTTGGGCATCCCTATCAAGAAAAAGACTATGTTGTGGT
CGGTGCAACGCCGGAACACATGCTCGCCCAAGGTTTTCAACCTGTAGGCAAAGATTTCCCTGTGTTTCTTCATCCCGAAA
CCAAGGAAGAATACGCACTTGCACGAACCGAACGAAAGTCTGGACAGGGATATCACGGGTTTCAATTCTTTACTGATACA
ACCGTTAGTTTAGAAGATGACTTAATTCGTCGAGACTTAACCATTAATGCGATTGCAATGGATCAAGATGGTAAAATATA
TGATCCATATGGTGGCCAAAACGACTTAGAAAATAAAATTCTGCGCCACGTTTCAGAAGCTTTTGCTGAAGACCCTTTAC
GGGTATTGCGAGTCGCGCGTTTTGCCGCCCGATATTTCCCATATGGTTTTCAAATTGCGCCAGAGACATTGCAACTTATG
CAAACCATGGCAGATTCAGGTGAACTTGATGCACTAACACCAGAGCGCGTCTGGAAAGAAACTTCACGCGCTTTAATGGA
AAATCATGCCGATATTTATTTCCAAACTTTGCGTGATTGTGGGGCTTTAAAACATCTTTTCCCTGAGATTGATGCTTTAT
TCGGTGTGCCTCAACGTCCCGAATATCATCCTGAAGTGGATTGCGGCATTCATACTTTAATGTCATTACAGCAAGCTTGT
AAGTCGAACTACTCGCTTGATGTACGTTTCGCTGTTTTAGTGCATGATCTTGGTAAGGCCCTCACTCCAGCCGAAGAACT
TCCTCGCCATATCATGCATGAAGAACGCGGGATTAAGCCAGTTACCCAATTATGTGAACGTTTAAGAGTTCCGACACAGA
CCAAACAATTAGCCTTATCTGTTTGTAAAGAACATTTAAAATGTCATCAGATTATGTCCTTGAAACCTGGTACTTTATGG
CGTCTATTGCAACGCTTAGATGTTTTACGTCGCCCAGAAAGAGTGGAAGCTTTTGTACAAGCCTGCGAATGTGATGCAAA
AGGCAGATTAGGACTAGAAGATCGTCCATATCCTCAAGCTCAATACATGCGTGAAGCCATGCAAATTGTTCGCTCCATTA
AAGTTCAAGATTTACCAGAGAACATTAAGGGTGCTGAAATTGGTGAAATGCTTATTCAATATCGAATTGAAGCTTTAGCT
GAATTTAAAAATCAGCATCAAAGTCTTAGTCACTCCTAA

Upstream 100 bases:

>100_bases
GAAAAGTAATTTAGAAACCGCTTTTTACGAAAAGCCTTTCTAATGACTTGAGAAAACCTCTATTCTGTAGCATGATTGCT
TGAAGAATAGAGGTTTTTTC

Downstream 100 bases:

>100_bases
TAAACAACAATAAAAAAAGCCTCAAAATGAGGCTTTTTTTATTTAGGTTTTAACGTCTTGGAAGCGGAATATACTGAGAT
TGTGTATTCTGTGCTTTTCG

Product: multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase

Products: NA

Alternate protein names: CCA-adding enzyme; tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl-transferase; tRNA nucleotidyltransferase; tRNA-NT; 2'-nucleotidase; 2',3'-cyclic phosphodiesterase; Phosphatase

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MQVYLVGGAVRDYLLGHPYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYALARTERKSGQGYHGFQFFTDT
TVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKILRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLM
QTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQAC
KSNYSLDVRFAVLVHDLGKALTPAEELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKCHQIMSLKPGTLW
RLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALA
EFKNQHQSLSHS

Sequences:

>Translated_412_residues
MQVYLVGGAVRDYLLGHPYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYALARTERKSGQGYHGFQFFTDT
TVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKILRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLM
QTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQAC
KSNYSLDVRFAVLVHDLGKALTPAEELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKCHQIMSLKPGTLW
RLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALA
EFKNQHQSLSHS
>Mature_412_residues
MQVYLVGGAVRDYLLGHPYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYALARTERKSGQGYHGFQFFTDT
TVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKILRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLM
QTMADSGELDALTPERVWKETSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQAC
KSNYSLDVRFAVLVHDLGKALTPAEELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALSVCKEHLKCHQIMSLKPGTLW
RLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQAQYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALA
EFKNQHQSLSHS

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG0617

COG function: function code J; tRNA nucleotidyltransferase/poly(A) polymerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily

Homologues:

Organism=Homo sapiens, GI155030240, Length=204, Percent_Identity=32.3529411764706, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789436, Length=406, Percent_Identity=56.6502463054187, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI87081691, Length=229, Percent_Identity=31.0043668122271, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281360112, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21357337, Length=240, Percent_Identity=27.9166666666667, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCA_ACIB3 (B7GZN3)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002325010.1
- ProteinModelPortal:   B7GZN3
- SMR:   B7GZN3
- GeneID:   7057888
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_001102
- HOGENOM:   HBG635063
- OMA:   RWACLLH
- ProtClustDB:   PRK10885
- HAMAP:   MF_01261
- InterPro:   IPR012006
- InterPro:   IPR003607
- InterPro:   IPR002646
- PIRSF:   PIRSF000813
- SMART:   SM00471

Pfam domain/function: PF01743 PolyA_pol

EC number: =2.7.7.21; =2.7.7.25

Molecular weight: Translated: 47190; Mature: 47190

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: BINDING 8-8 BINDING 11-11 BINDING 91-91 BINDING 137-137 BINDING 140-140

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MQVYLVGGAVRDYLLGHPYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYAL
CEEEEECHHHHHHHHCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCEEECCCCHHHHHH
ARTERKSGQGYHGFQFFTDTTVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKI
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCEECCCCCCCHHHHHH
LRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLMQTMADSGELDALTPERVWKE
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCCCCCCCCHHHHHHH
TSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
KSNYSLDVRFAVLVHDLGKALTPAEELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALS
HCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
VCKEHLKCHQIMSLKPGTLWRLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
QYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALAEFKNQHQSLSHS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVYLVGGAVRDYLLGHPYQEKDYVVVGATPEHMLAQGFQPVGKDFPVFLHPETKEEYAL
CEEEEECHHHHHHHHCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCEEECCCCHHHHHH
ARTERKSGQGYHGFQFFTDTTVSLEDDLIRRDLTINAIAMDQDGKIYDPYGGQNDLENKI
HHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCEEEEEEECCCCCEECCCCCCCHHHHHH
LRHVSEAFAEDPLRVLRVARFAARYFPYGFQIAPETLQLMQTMADSGELDALTPERVWKE
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHCCCCCCCCCHHHHHHH
TSRALMENHADIYFQTLRDCGALKHLFPEIDALFGVPQRPEYHPEVDCGIHTLMSLQQAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
KSNYSLDVRFAVLVHDLGKALTPAEELPRHIMHEERGIKPVTQLCERLRVPTQTKQLALS
HCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
VCKEHLKCHQIMSLKPGTLWRLLQRLDVLRRPERVEAFVQACECDAKGRLGLEDRPYPQA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
QYMREAMQIVRSIKVQDLPENIKGAEIGEMLIQYRIEALAEFKNQHQSLSHS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA