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The map label for this gene is hflX [H]

Identifier: 213157950

GI number: 213157950

Start: 3556241

End: 3557575

Strand: Direct

Name: hflX [H]

Synonym: AB57_3444

Alternate gene names: 213157950

Gene position: 3556241-3557575 (Clockwise)

Preceding gene: 213157948

Following gene: 213157951

Centisome position: 87.8

GC content: 40.9

Gene sequence:

>1335_bases
GTGGAATATGTTGATCGGCATCAAGGCGGTGAACGCACAATATTAGTGAGTGTGTCTGTACAATTATTAGATGATCTGGA
TGCCGAAGAATTTGCTCTACTTGCACAGTCAGCTGGTGCAGATATTCTTGAGCACATTAAAGTTCAACGTAATAAACCGG
ACCCTAAGTTTTTTATTGGTTCAGGTAAAGTTGATGAGATTGCAGAACAAGTTCAGGAATTAGAAGCAAGTCTTGTTATT
TTTGATCATGCATTAACCCCTGCCCAAGAGCGTAATTTAGAAAAGATTTTAAAATGCCGCGTTATTGACCGCACCGGTCT
CATCTTAGATATTTTTGCCCAGCGCGCGCGGACCCATGAAGGTAAATTACAAGTTGAACTTGCTCAGTTAAAACATTTAT
CAACCCGTTTAATCCGTGGTTGGTCTGCTGATTTTGAACAACAAAAAGGTGGTATTGGTTTACGCGGTCCCGGTGAATCA
CAACTCGAAACAGACCGTCGTCTCATTCGTGTCCGTATTACCCAGTTAAAAGATAAGTTAGAGAAAGTCCATCAAACCCG
TATGCAAGGACGAGCTGCAAGACAAAAAGCTTCGATCCCAACTGTTTCATTAGTCGGTTATACCAACGCGGGTAAATCAA
CCTTATTTAATATTTTAGCGAAAAGTGATGTATATGCAGCCGACCAACTATTTGCAACACTTGATCCAACCTTACGTCGT
CTAGAATGGGATGGAATTGGTACGGTGGTTCTAGCAGATACGGTAGGGTTCGTACGAAACTTACAACATGATTTGGTCGA
ATCATTTAAAGCAACTTTAGAAGAAACGCTTGAAGCTACCCTGCTTTTACATGTCATCGATAGCAGTAGTCATGACATGC
TTGACCAGATTGAAGCCGTTGAAGGTGTATTGAAGGAAATTGGAGCGGATGCACCCGTACTTCGTGTTTATAACAAAATT
GATTTGAGTGGCGAAGAAGCAAAAATTATTTATTCAGAGCCCCATGTTCCAGATCGTGTTTATGTATCTGCACACTCAGG
GTTAGGTCTAGATTTACTTCGCCAAGCCGTACAAGAGTGTCTAATGGGACAACTTCAACACTTCTCATTGGTACTTAAAC
CTGCTTATGGCAAATTGCGTACTCAACTTTATGCTTTAAATGTCATTCAATCTGAGCATTATGACGATGAAGGGCTATTA
CATATTGATATACGAATTGCACCTCATAAGCTTGAGCAGTTAATTCGCCAAGCCAAACTCCCTATAGATGAGATATTAGG
TGAACGCGCAAGTCAGTTTAAAAGACCACTGGAAGAGTTTGAAATCAAGCACTAG

Upstream 100 bases:

>100_bases
ATGCGCTGTAGTTAATCTAAAGAATAAGAGTAAACCCTTTCCCCTTTTGCCCAAGTTTCCTCTAGAATAAAGTTTTACCT
TATTCAGGATTTATAGCCAA

Downstream 100 bases:

>100_bases
ATCAGTTAAAACTTGATAAGTAAACTTTTAGAGATAAAAAATATGGATAAGATCAAAAGTATAGACTGGGCAGCATGGGT
AGGAACCTTACTACTTATTA

Product: GTP-binding proten

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MEYVDRHQGGERTILVSVSVQLLDDLDAEEFALLAQSAGADILEHIKVQRNKPDPKFFIGSGKVDEIAEQVQELEASLVI
FDHALTPAQERNLEKILKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLKHLSTRLIRGWSADFEQQKGGIGLRGPGES
QLETDRRLIRVRITQLKDKLEKVHQTRMQGRAARQKASIPTVSLVGYTNAGKSTLFNILAKSDVYAADQLFATLDPTLRR
LEWDGIGTVVLADTVGFVRNLQHDLVESFKATLEETLEATLLLHVIDSSSHDMLDQIEAVEGVLKEIGADAPVLRVYNKI
DLSGEEAKIIYSEPHVPDRVYVSAHSGLGLDLLRQAVQECLMGQLQHFSLVLKPAYGKLRTQLYALNVIQSEHYDDEGLL
HIDIRIAPHKLEQLIRQAKLPIDEILGERASQFKRPLEEFEIKH

Sequences:

>Translated_444_residues
MEYVDRHQGGERTILVSVSVQLLDDLDAEEFALLAQSAGADILEHIKVQRNKPDPKFFIGSGKVDEIAEQVQELEASLVI
FDHALTPAQERNLEKILKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLKHLSTRLIRGWSADFEQQKGGIGLRGPGES
QLETDRRLIRVRITQLKDKLEKVHQTRMQGRAARQKASIPTVSLVGYTNAGKSTLFNILAKSDVYAADQLFATLDPTLRR
LEWDGIGTVVLADTVGFVRNLQHDLVESFKATLEETLEATLLLHVIDSSSHDMLDQIEAVEGVLKEIGADAPVLRVYNKI
DLSGEEAKIIYSEPHVPDRVYVSAHSGLGLDLLRQAVQECLMGQLQHFSLVLKPAYGKLRTQLYALNVIQSEHYDDEGLL
HIDIRIAPHKLEQLIRQAKLPIDEILGERASQFKRPLEEFEIKH
>Mature_444_residues
MEYVDRHQGGERTILVSVSVQLLDDLDAEEFALLAQSAGADILEHIKVQRNKPDPKFFIGSGKVDEIAEQVQELEASLVI
FDHALTPAQERNLEKILKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLKHLSTRLIRGWSADFEQQKGGIGLRGPGES
QLETDRRLIRVRITQLKDKLEKVHQTRMQGRAARQKASIPTVSLVGYTNAGKSTLFNILAKSDVYAADQLFATLDPTLRR
LEWDGIGTVVLADTVGFVRNLQHDLVESFKATLEETLEATLLLHVIDSSSHDMLDQIEAVEGVLKEIGADAPVLRVYNKI
DLSGEEAKIIYSEPHVPDRVYVSAHSGLGLDLLRQAVQECLMGQLQHFSLVLKPAYGKLRTQLYALNVIQSEHYDDEGLL
HIDIRIAPHKLEQLIRQAKLPIDEILGERASQFKRPLEEFEIKH

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=204, Percent_Identity=36.7647058823529, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI310124267, Length=204, Percent_Identity=36.7647058823529, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI310124171, Length=204, Percent_Identity=36.7647058823529, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI310124169, Length=204, Percent_Identity=36.7647058823529, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI310133118, Length=212, Percent_Identity=36.3207547169811, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310133116, Length=212, Percent_Identity=36.3207547169811, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1790615, Length=425, Percent_Identity=55.2941176470588, Blast_Score=445, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17561038, Length=274, Percent_Identity=31.021897810219, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24650079, Length=414, Percent_Identity=29.2270531400966, Blast_Score=126, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49932; Mature: 49932

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVDRHQGGERTILVSVSVQLLDDLDAEEFALLAQSAGADILEHIKVQRNKPDPKFFIG
CCCCCCCCCCCEEEEEEEEHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEC
SGKVDEIAEQVQELEASLVIFDHALTPAQERNLEKILKCRVIDRTGLILDIFAQRARTHE
CCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GKLQVELAQLKHLSTRLIRGWSADFEQQKGGIGLRGPGESQLETDRRLIRVRITQLKDKL
CCEEEHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EKVHQTRMQGRAARQKASIPTVSLVGYTNAGKSTLFNILAKSDVYAADQLFATLDPTLRR
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHH
LEWDGIGTVVLADTVGFVRNLQHDLVESFKATLEETLEATLLLHVIDSSSHDMLDQIEAV
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EGVLKEIGADAPVLRVYNKIDLSGEEAKIIYSEPHVPDRVYVSAHSGLGLDLLRQAVQEC
HHHHHHHCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHH
LMGQLQHFSLVLKPAYGKLRTQLYALNVIQSEHYDDEGLLHIDIRIAPHKLEQLIRQAKL
HHHHHHHHHHEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHCC
PIDEILGERASQFKRPLEEFEIKH
CHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MEYVDRHQGGERTILVSVSVQLLDDLDAEEFALLAQSAGADILEHIKVQRNKPDPKFFIG
CCCCCCCCCCCEEEEEEEEHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEC
SGKVDEIAEQVQELEASLVIFDHALTPAQERNLEKILKCRVIDRTGLILDIFAQRARTHE
CCCHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GKLQVELAQLKHLSTRLIRGWSADFEQQKGGIGLRGPGESQLETDRRLIRVRITQLKDKL
CCEEEHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EKVHQTRMQGRAARQKASIPTVSLVGYTNAGKSTLFNILAKSDVYAADQLFATLDPTLRR
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHCHHHHH
LEWDGIGTVVLADTVGFVRNLQHDLVESFKATLEETLEATLLLHVIDSSSHDMLDQIEAV
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EGVLKEIGADAPVLRVYNKIDLSGEEAKIIYSEPHVPDRVYVSAHSGLGLDLLRQAVQEC
HHHHHHHCCCCCHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHH
LMGQLQHFSLVLKPAYGKLRTQLYALNVIQSEHYDDEGLLHIDIRIAPHKLEQLIRQAKL
HHHHHHHHHHEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECHHHHHHHHHHHCC
PIDEILGERASQFKRPLEEFEIKH
CHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]