Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 213157887

GI number: 213157887

Start: 3483337

End: 3484566

Strand: Reverse

Name: trpB [H]

Synonym: AB57_3379

Alternate gene names: 213157887

Gene position: 3484566-3483337 (Counterclockwise)

Preceding gene: 213157888

Following gene: 213157886

Centisome position: 86.03

GC content: 44.07

Gene sequence:

>1230_bases
GTGGATCAGCAAAATAATATGATTGACTATACCCAATTCCCAGATGCAAATGGGCATTTCGGTATCCATGGCGGACGTTT
TGTGTCAGAAACTTTAATGGCGGCATTAGAAGATTTGGAAAATCTCTATTCCCGCATGAAAAATGATGAACAGTTTTTGG
CAGAATTCGACCGTGACCTCGCCTACTATGTAGGTCGTCCTAGTCCACTTTATTATGCTGAGCGATGGTCAAAAGAGTTA
GGTGGTGCGCAAATTTACCTTAAACGTGAAGACTTGAACCATACTGGCTCACACAAGGTAAACAACACGATTGGTCAGGC
GTTATTGGCAAAGCTTTCTGGTAAAAAACGTATTATTGCCGAAACTGGTGCAGGGCAGCATGGTGTAGCGACAGCAACAA
TTGCAGCACGTTTAGGTCTTGAATGTGTTGTTTATATGGGTGCTGAAGACGTTAAGCGTCAAGCGATGAACGTTTACCGT
ATGCGTTTGTTAGGCGCTACAGTTGTTCCTGTACAAAGTGGCTCTAAAACGTTGAAAGACGCCATGAACGAAGCGATGCG
TGACTGGGTAACTAATGTTGATACGACGTACTATGTGATTGGTACGGTTGCAGGCCCGCATCCATATCCTCAATTGGTTC
GTGACTTCCAGTCGATTATTGGTCGTGAAGCGCGTAAACAGATTTTGGAACAAGCAGGTCGTTTACCAGATGCATTAGTT
GCCTGTGTAGGTGGCGGTTCAAATGCAATGGGCTTGTTCTATCCGTTTTTAAACGATGCCAATGTGAAAATGTATGGTGT
TGAAGCCGCTGGTTTTGGTATTGAAACTGGTAAACACTCTGCGCCGTTAAATGCGGGTCATGTGGGTGTATTGCACGGTA
ACCGTACTTACTTGATGAGTGATGAACAAGGCCAGATTATTGAGACACATAGTATCTCAGCAGGTCTTGACTATCCGGGT
GTTGGCCCTGAACATAGCTTCTTGAAAGATATGAAGCGTGTAGAGTACGTGCCGATTAATGATACAGAAGCTCTACAAGG
TTTCCGCGACTTAACTAAAATCGAAGGGATTATTCCTGCACTTGAAAGCTCGCATGCGATGGCCTATGTCTCTAAGCTTG
CACCGACGATGTCTAAAGATCAGATTATTATTGCGACTGTTTCAGGTCGTGGTGATAAAGATTTAATGACAGTTGCACGT
ATTGATGGCGTAGAAATGGTCGAGATGTAA

Upstream 100 bases:

>100_bases
ACTACCGGTGCTTTTGCAGTAGATGTGAGCGGAGGCGTAGAGTCCGCAAAAGGTATAAAAGACCAACAACTCATTGAACG
ATTTATGCAAGGAGTCCAAC

Downstream 100 bases:

>100_bases
GAGGATATAATGCCAAGTTTGTTTATGGTGATGTTAGGCGGGCGTCATGCACGCGCTAATACAGAAGTTCATGATGTAGT
CATGGCTGTAGGAGATACTT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDQQNNMIDYTQFPDANGHFGIHGGRFVSETLMAALEDLENLYSRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKEL
GGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVYMGAEDVKRQAMNVYR
MRLLGATVVPVQSGSKTLKDAMNEAMRDWVTNVDTTYYVIGTVAGPHPYPQLVRDFQSIIGREARKQILEQAGRLPDALV
ACVGGGSNAMGLFYPFLNDANVKMYGVEAAGFGIETGKHSAPLNAGHVGVLHGNRTYLMSDEQGQIIETHSISAGLDYPG
VGPEHSFLKDMKRVEYVPINDTEALQGFRDLTKIEGIIPALESSHAMAYVSKLAPTMSKDQIIIATVSGRGDKDLMTVAR
IDGVEMVEM

Sequences:

>Translated_409_residues
MDQQNNMIDYTQFPDANGHFGIHGGRFVSETLMAALEDLENLYSRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKEL
GGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVYMGAEDVKRQAMNVYR
MRLLGATVVPVQSGSKTLKDAMNEAMRDWVTNVDTTYYVIGTVAGPHPYPQLVRDFQSIIGREARKQILEQAGRLPDALV
ACVGGGSNAMGLFYPFLNDANVKMYGVEAAGFGIETGKHSAPLNAGHVGVLHGNRTYLMSDEQGQIIETHSISAGLDYPG
VGPEHSFLKDMKRVEYVPINDTEALQGFRDLTKIEGIIPALESSHAMAYVSKLAPTMSKDQIIIATVSGRGDKDLMTVAR
IDGVEMVEM
>Mature_409_residues
MDQQNNMIDYTQFPDANGHFGIHGGRFVSETLMAALEDLENLYSRMKNDEQFLAEFDRDLAYYVGRPSPLYYAERWSKEL
GGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIAETGAGQHGVATATIAARLGLECVVYMGAEDVKRQAMNVYR
MRLLGATVVPVQSGSKTLKDAMNEAMRDWVTNVDTTYYVIGTVAGPHPYPQLVRDFQSIIGREARKQILEQAGRLPDALV
ACVGGGSNAMGLFYPFLNDANVKMYGVEAAGFGIETGKHSAPLNAGHVGVLHGNRTYLMSDEQGQIIETHSISAGLDYPG
VGPEHSFLKDMKRVEYVPINDTEALQGFRDLTKIEGIIPALESSHAMAYVSKLAPTMSKDQIIIATVSGRGDKDLMTVAR
IDGVEMVEM

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=54.4041450777202, Blast_Score=429, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6321412, Length=383, Percent_Identity=56.9190600522193, Blast_Score=457, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44841; Mature: 44841

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQQNNMIDYTQFPDANGHFGIHGGRFVSETLMAALEDLENLYSRMKNDEQFLAEFDRDL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHH
AYYVGRPSPLYYAERWSKELGGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIA
HHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
ETGAGQHGVATATIAARLGLECVVYMGAEDVKRQAMNVYRMRLLGATVVPVQSGSKTLKD
ECCCCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHH
AMNEAMRDWVTNVDTTYYVIGTVAGPHPYPQLVRDFQSIIGREARKQILEQAGRLPDALV
HHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ACVGGGSNAMGLFYPFLNDANVKMYGVEAAGFGIETGKHSAPLNAGHVGVLHGNRTYLMS
EEECCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEEEE
DEQGQIIETHSISAGLDYPGVGPEHSFLKDMKRVEYVPINDTEALQGFRDLTKIEGIIPA
CCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHH
LESSHAMAYVSKLAPTMSKDQIIIATVSGRGDKDLMTVARIDGVEMVEM
HCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCEEEECC
>Mature Secondary Structure
MDQQNNMIDYTQFPDANGHFGIHGGRFVSETLMAALEDLENLYSRMKNDEQFLAEFDRDL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHH
AYYVGRPSPLYYAERWSKELGGAQIYLKREDLNHTGSHKVNNTIGQALLAKLSGKKRIIA
HHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
ETGAGQHGVATATIAARLGLECVVYMGAEDVKRQAMNVYRMRLLGATVVPVQSGSKTLKD
ECCCCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHH
AMNEAMRDWVTNVDTTYYVIGTVAGPHPYPQLVRDFQSIIGREARKQILEQAGRLPDALV
HHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ACVGGGSNAMGLFYPFLNDANVKMYGVEAAGFGIETGKHSAPLNAGHVGVLHGNRTYLMS
EEECCCCCCCEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEEEE
DEQGQIIETHSISAGLDYPGVGPEHSFLKDMKRVEYVPINDTEALQGFRDLTKIEGIIPA
CCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHH
LESSHAMAYVSKLAPTMSKDQIIIATVSGRGDKDLMTVARIDGVEMVEM
HCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA