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The map label for this gene is namA [H]

Identifier: 213157844

GI number: 213157844

Start: 3433644

End: 3434750

Strand: Reverse

Name: namA [H]

Synonym: AB57_3328

Alternate gene names: 213157844

Gene position: 3434750-3433644 (Counterclockwise)

Preceding gene: 213157845

Following gene: 213157843

Centisome position: 84.8

GC content: 42.82

Gene sequence:

>1107_bases
ATGGCAAAATTATTTGAAACGGTTAATTTCGATTCACTACAACTGGTCAATAGAATTGTAATTGCCCCAATGTGCCAATA
TTCGGCAACAGATGAAGGCGAAATTACCTATTGGCATGAACAGCAATGGGCAAATTACGCGTTGTCTGGAGCTGGGCTAT
GTATTGTGGAAGCTACAGCTGTACAGGCGGAAGGTCGAATTAGTTATGCAGACCTTGGCCTTTGGAATGATCAGCAACGT
GACCAGATCAAAACTTTATTGGGAAAAGTTAAAACACTTTCTCCTATGCCATTTGGAATTCAATTAGCTCATGCTGGACG
TAAGGCATCTACTGAAAAGCCTTGGTTAGGTAAAGGCCAAATTGCAAAAGATCAGCCACATGGTTGGCAAACAGTTGCTC
CAAGTACAAGTACTTTTTCGGTTCACGATGCAGCGCCACATGCTTTAACCATTGCCGAGATTAAACAAATTCAACAAGAC
TTTGCAGCTGCGGCAAAACGTGCAGTTGAAGCGGGCTTTGAGCTAATTGAGGTACATGCTGCTCATGGTTACTTGCTACA
CCAATTCTTATCGCCAATTGCCAATCAACGTACTGATGAATATGGTGGCTCTTTAGAAAACCGTATGCGTATGACGTTAG
AGGTACTTCAGGCGATTAAACTTGCTGTTCCCGAAGGTTATCCGGTAGGGGTACGTTTATCTGCAACAGACTGGATGGAT
GGTAATGAACAGTGGGATATTGAGTCTACGGTTGGTTTATCAAAAGCCTTAGAGCAGTTAGGTGCGGCCTATATTCATGT
CTCTAGTGGTGGTTTACATGAGCATCAAAATATTACTATTGGAGCAGGTTACCAAGTTCCTTTCGCGGAACAGGTTAAAA
AACATGTAGCTATTCCTGTGATTGCGGTAGGTCTCATTACTGACCCACAGCATGCTGAACAAATTTTAGAAAACCAAGCT
GATGCCATTGGTCTTGCGCGTGCAATGTTATATGACCCACGTTGGCCATGGCATGCTGCTGCTACATTAGGTGCAAAAGT
CAAAATTGCTCCTCAATATTTGCGTTGCCAACCACATGGCTTAAAACAGCTTTTTGATTCTTTTTAG

Upstream 100 bases:

>100_bases
AGTTATTGTAAATGACGGTAATAGCCGCTATTTCGAACCTGCTGATGGACGTAACTGGAGTGCAGGTTTACGTGTAATTA
AACAATTCTAGGAATTAAAA

Downstream 100 bases:

>100_bases
TTTTTAATATTCGGGCAAATTAAGATTTGCCCGTTTTTCTTTTGAAATGAGTGAGGAAGTAGTCTGTGGTTTTTCAGGTA
ATTTTACCAATTTTGATTTT

Product: NADPH dehydrogenase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MAKLFETVNFDSLQLVNRIVIAPMCQYSATDEGEITYWHEQQWANYALSGAGLCIVEATAVQAEGRISYADLGLWNDQQR
DQIKTLLGKVKTLSPMPFGIQLAHAGRKASTEKPWLGKGQIAKDQPHGWQTVAPSTSTFSVHDAAPHALTIAEIKQIQQD
FAAAAKRAVEAGFELIEVHAAHGYLLHQFLSPIANQRTDEYGGSLENRMRMTLEVLQAIKLAVPEGYPVGVRLSATDWMD
GNEQWDIESTVGLSKALEQLGAAYIHVSSGGLHEHQNITIGAGYQVPFAEQVKKHVAIPVIAVGLITDPQHAEQILENQA
DAIGLARAMLYDPRWPWHAAATLGAKVKIAPQYLRCQPHGLKQLFDSF

Sequences:

>Translated_368_residues
MAKLFETVNFDSLQLVNRIVIAPMCQYSATDEGEITYWHEQQWANYALSGAGLCIVEATAVQAEGRISYADLGLWNDQQR
DQIKTLLGKVKTLSPMPFGIQLAHAGRKASTEKPWLGKGQIAKDQPHGWQTVAPSTSTFSVHDAAPHALTIAEIKQIQQD
FAAAAKRAVEAGFELIEVHAAHGYLLHQFLSPIANQRTDEYGGSLENRMRMTLEVLQAIKLAVPEGYPVGVRLSATDWMD
GNEQWDIESTVGLSKALEQLGAAYIHVSSGGLHEHQNITIGAGYQVPFAEQVKKHVAIPVIAVGLITDPQHAEQILENQA
DAIGLARAMLYDPRWPWHAAATLGAKVKIAPQYLRCQPHGLKQLFDSF
>Mature_367_residues
AKLFETVNFDSLQLVNRIVIAPMCQYSATDEGEITYWHEQQWANYALSGAGLCIVEATAVQAEGRISYADLGLWNDQQRD
QIKTLLGKVKTLSPMPFGIQLAHAGRKASTEKPWLGKGQIAKDQPHGWQTVAPSTSTFSVHDAAPHALTIAEIKQIQQDF
AAAAKRAVEAGFELIEVHAAHGYLLHQFLSPIANQRTDEYGGSLENRMRMTLEVLQAIKLAVPEGYPVGVRLSATDWMDG
NEQWDIESTVGLSKALEQLGAAYIHVSSGGLHEHQNITIGAGYQVPFAEQVKKHVAIPVIAVGLITDPQHAEQILENQAD
AIGLARAMLYDPRWPWHAAATLGAKVKIAPQYLRCQPHGLKQLFDSF

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=369, Percent_Identity=30.8943089430894, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789463, Length=374, Percent_Identity=27.807486631016, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI72001454, Length=248, Percent_Identity=31.8548387096774, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17540738, Length=248, Percent_Identity=30.241935483871, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17559804, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=250, Percent_Identity=30.4, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=248, Percent_Identity=28.2258064516129, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=252, Percent_Identity=31.3492063492063, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17566914, Length=133, Percent_Identity=36.8421052631579, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=237, Percent_Identity=32.9113924050633, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=236, Percent_Identity=31.7796610169492, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40428; Mature: 40297

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLFETVNFDSLQLVNRIVIAPMCQYSATDEGEITYWHEQQWANYALSGAGLCIVEATA
CCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHEECCCCEEEEEEEE
VQAEGRISYADLGLWNDQQRDQIKTLLGKVKTLSPMPFGIQLAHAGRKASTEKPWLGKGQ
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
IAKDQPHGWQTVAPSTSTFSVHDAAPHALTIAEIKQIQQDFAAAAKRAVEAGFELIEVHA
CCCCCCCCCEEECCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHEEEEHH
AHGYLLHQFLSPIANQRTDEYGGSLENRMRMTLEVLQAIKLAVPEGYPVGVRLSATDWMD
HHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
GNEQWDIESTVGLSKALEQLGAAYIHVSSGGLHEHQNITIGAGYQVPFAEQVKKHVAIPV
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
IAVGLITDPQHAEQILENQADAIGLARAMLYDPRWPWHAAATLGAKVKIAPQYLRCQPHG
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECHHHHCCCCCH
LKQLFDSF
HHHHHHCC
>Mature Secondary Structure 
AKLFETVNFDSLQLVNRIVIAPMCQYSATDEGEITYWHEQQWANYALSGAGLCIVEATA
CCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHEECCCCEEEEEEEE
VQAEGRISYADLGLWNDQQRDQIKTLLGKVKTLSPMPFGIQLAHAGRKASTEKPWLGKGQ
ECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
IAKDQPHGWQTVAPSTSTFSVHDAAPHALTIAEIKQIQQDFAAAAKRAVEAGFELIEVHA
CCCCCCCCCEEECCCCCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCHHEEEEHH
AHGYLLHQFLSPIANQRTDEYGGSLENRMRMTLEVLQAIKLAVPEGYPVGVRLSATDWMD
HHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
GNEQWDIESTVGLSKALEQLGAAYIHVSSGGLHEHQNITIGAGYQVPFAEQVKKHVAIPV
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCCE
IAVGLITDPQHAEQILENQADAIGLARAMLYDPRWPWHAAATLGAKVKIAPQYLRCQPHG
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCEEEECHHHHCCCCCH
LKQLFDSF
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA