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The map label for this gene is sucD [H]

Identifier: 213157645

GI number: 213157645

Start: 3244274

End: 3245164

Strand: Reverse

Name: sucD [H]

Synonym: AB57_3122

Alternate gene names: 213157645

Gene position: 3245164-3244274 (Counterclockwise)

Preceding gene: 213157646

Following gene: 213157643

Centisome position: 80.12

GC content: 42.99

Gene sequence:

>891_bases
ATGAGCGTATTAATTAATAAAGACACTAAAGTATTGGTACAAGGTTTTACTGGTAAAAACGGTACTTTCCACTCTGCACA
AGCTTTAGACTACGGTACAAAAGTTGTTGGTGGTGTTACTCCAGGTAAAGGTGGTACAACTCACCTTGACTTACCAGTAT
TCAACACAATGAAAGAAGCTGTACGTGAAACAAATGCAGATGCATCTGTAATCTATGTACCAGCTCCATTCGTTTTAGAC
TCAATCGTTGAAGCGGTTGATTCAGGAGTTGGCCTAATCGTTGTGATCACTGAAGGCGTTCCAACAATCGACATGCTTAA
AGCAAAACGTTATTTAGAAACTAACGGTAACGGTACTCGTTTAGTTGGTCCTAACTGCCCAGGCGTGATCACTCCAGGTG
AATGTAAGATCGGTATTATGCCTGGTCACATCCACCAACCAGGTCGTATTGGTATCATTTCACGTTCAGGTACATTGACT
TATGAAGCTGTTGCTCAAACAACTAAGCTTGGTTTAGGTCAGTCTACTTGTATCGGTATCGGTGGTGACCCAATCCCAGG
TATGAACCAAATTGAAGCTCTTCAATTGTTCCAAGACGATCCAGATACTGATGCAATCATCATGATCGGTGAGATCGGTG
GTACAGCGGAAGAAGAGGCTGCTGAATTCATCAAATCTAACGTGACTAAACCTGTAGTAGGTTACATCGCTGGTGTAACC
GCGCCTAAAGGTAAGCGTATGGGTCACGCTGGTGCGATCATTTCTGGTGGTCAAGGTACTGCTGAAGAGAAATTCGCTGC
ATTTGAAAAAGCAGGTATGGCTTACACTCGTAGCCCAGCTGAGCTTGGTTCAACTATGTTGCAAGTATTAAAAGAGAAAG
GTTTAGCGTAA

Upstream 100 bases:

>100_bases
TACTTGATGAATCTGGTTTGAAATTAATTTCTGCGAACGGTTTGTCTGATGCCGCAGAAAAAGTTGTAGCTGCAGTTAAA
GCGTAAGGGGAGTATCAATC

Downstream 100 bases:

>100_bases
TTCGTTAGATTTTGATCTTTAAAAAACCCCAATGGAGACATTGGGGTTTTTTATTAAAATGAAATGATATTAATTCTAGT
AGAACATTGAATAATTAACA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKEAVRETNADASVIYVPAPFVLD
SIVEAVDSGVGLIVVITEGVPTIDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLT
YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIEALQLFQDDPDTDAIIMIGEIGGTAEEEAAEFIKSNVTKPVVGYIAGVT
APKGKRMGHAGAIISGGQGTAEEKFAAFEKAGMAYTRSPAELGSTMLQVLKEKGLA

Sequences:

>Translated_296_residues
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKEAVRETNADASVIYVPAPFVLD
SIVEAVDSGVGLIVVITEGVPTIDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLT
YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIEALQLFQDDPDTDAIIMIGEIGGTAEEEAAEFIKSNVTKPVVGYIAGVT
APKGKRMGHAGAIISGGQGTAEEKFAAFEKAGMAYTRSPAELGSTMLQVLKEKGLA
>Mature_295_residues
SVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKEAVRETNADASVIYVPAPFVLDS
IVEAVDSGVGLIVVITEGVPTIDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTY
EAVAQTTKLGLGQSTCIGIGGDPIPGMNQIEALQLFQDDPDTDAIIMIGEIGGTAEEEAAEFIKSNVTKPVVGYIAGVTA
PKGKRMGHAGAIISGGQGTAEEKFAAFEKAGMAYTRSPAELGSTMLQVLKEKGLA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=60.6060606060606, Blast_Score=318, Evalue=3e-87,
Organism=Homo sapiens, GI38569423, Length=262, Percent_Identity=30.1526717557252, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI38569421, Length=262, Percent_Identity=30.1526717557252, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=71.1340206185567, Blast_Score=427, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17550194, Length=286, Percent_Identity=61.8881118881119, Blast_Score=332, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=60.4095563139932, Blast_Score=331, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17551266, Length=323, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17557344, Length=320, Percent_Identity=28.125, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=53.0612244897959, Blast_Score=286, Evalue=4e-78,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=58.3333333333333, Blast_Score=343, Evalue=7e-95,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=58.5616438356164, Blast_Score=318, Evalue=2e-87,
Organism=Drosophila melanogaster, GI281363477, Length=262, Percent_Identity=27.8625954198473, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363475, Length=262, Percent_Identity=27.8625954198473, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363473, Length=262, Percent_Identity=27.8625954198473, Blast_Score=98, Evalue=5e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30694; Mature: 30562

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKEA
CEEEECCCCEEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCCCCEEECCCHHHHHHHH
VRETNADASVIYVPAPFVLDSIVEAVDSGVGLIVVITEGVPTIDMLKAKRYLETNGNGTR
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCE
LVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGI
EECCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIPGMNQIEALQLFQDDPDTDAIIMIGEIGGTAEEEAAEFIKSNVTKPVVGYIAGVT
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
APKGKRMGHAGAIISGGQGTAEEKFAAFEKAGMAYTRSPAELGSTMLQVLKEKGLA
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVLINKDTKVLVQGFTGKNGTFHSAQALDYGTKVVGGVTPGKGGTTHLDLPVFNTMKEA
EEEECCCCEEEEEECCCCCCCCCCHHHHCCCCEEECCCCCCCCCCEEECCCHHHHHHHH
VRETNADASVIYVPAPFVLDSIVEAVDSGVGLIVVITEGVPTIDMLKAKRYLETNGNGTR
HHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCE
LVGPNCPGVITPGECKIGIMPGHIHQPGRIGIISRSGTLTYEAVAQTTKLGLGQSTCIGI
EECCCCCCEECCCCEEEEEECCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCEEEEC
GGDPIPGMNQIEALQLFQDDPDTDAIIMIGEIGGTAEEEAAEFIKSNVTKPVVGYIAGVT
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
APKGKRMGHAGAIISGGQGTAEEKFAAFEKAGMAYTRSPAELGSTMLQVLKEKGLA
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]