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The map label for this gene is sucC [H]

Identifier: 213157646

GI number: 213157646

Start: 3245179

End: 3246345

Strand: Reverse

Name: sucC [H]

Synonym: AB57_3123

Alternate gene names: 213157646

Gene position: 3246345-3245179 (Counterclockwise)

Preceding gene: 213157647

Following gene: 213157645

Centisome position: 80.15

GC content: 40.53

Gene sequence:

>1167_bases
ATGAACTTACATGAGTATCAAGCTAAAGCGTTATTGAAAGAATATGGTATGCCGGTACAAGAAGGTATCTTGGCAACCAA
TGCAGACGAAGCAGTTGCTGCATTTGAACAGCTTGGTGGTAAATTCGCTGTAATGAAGGCGCAAGTTCATGCTGGTGGTC
GTGGTAAGGCTGGTGGCGTTAAAGTTGCAAAATCTAAAGAAGATGTTATCGAATTTGCAAACAATATCATTGGTACTCGT
CTTGTAACGTATCAAACAGATGCAAATGGTCAACCAGTAAACAGCATCATTGTTGCTGAAGACGTATATCCAGTTGAGCG
TGAGCTTTACTTGGGCGCGGTTGTAGACCGTTCTAGCCGTCGTATTACTTTCATGGCTTCTACAGAAGGTGGTGTAGAAA
TCGAGAAAGTTGCGGAAGAAACTCCAGAAAAAATTATCAAAGTTGAAGTTGATCCATTAGTTGGTTTACAACCATTCCAA
GCACGTGAAGTTGCGTTTGCTTTAGGTTTGAAAGACAAGCAAATCGGTCAATTCGTGAAAATCATGACAGCTGCTTACCA
AGCATTTGTTGAAAATGATTTCGCTTTATTTGAAATTAACCCACTTTCAGTTCGTGAAAATGGCGAAATTTTATGTGTAG
ACGCGAAAGTAGGTATCGACTCTAACGCGCTTTACCGTTTACCTAAAGTTGCTGCTTTACGTGACAAATCTCAAGAGAAT
GAGCGTGAATTAAAAGCATCTGAATTTGATCTTAACTATGTTGCTTTAGAAGGTAACATTGGCTGTATGGTTAACGGTGC
TGGTCTTGCAATGGCAACTATGGACATCATTAAACTTTATGGTGGTCAGCCTGCAAACTTCCTTGACGTTGGTGGCGGTG
CAACTAAAGAGCGTGTAATCGAAGCGTTCAAAATCATTCTTGCTGATACGTCTGTACAAGGTGTTTTAATCAACATCTTC
GGTGGTATCGTACGTTGTGACATGATTGCTGAAGCAATTATTGCAGCGGTTCAAGAAGTAAACGTAACTGTTCCAGTTGT
TGTTCGTTTAGAAGGTAACAACGCTGAGTTAGGTGCGAAATTACTTGATGAATCTGGTTTGAAATTAATTTCTGCGAACG
GTTTGTCTGATGCCGCAGAAAAAGTTGTAGCTGCAGTTAAAGCGTAA

Upstream 100 bases:

>100_bases
AAAAATCATCAAGTTGATAGACGTAGACAGCAATTTGCTTATACAACATGAGAATGTTGCGCAAATTGAAGACAACAAAC
AAAGTTAAGTAGGTAACTAA

Downstream 100 bases:

>100_bases
GGGGAGTATCAATCATGAGCGTATTAATTAATAAAGACACTAAAGTATTGGTACAAGGTTTTACTGGTAAAAACGGTACT
TTCCACTCTGCACAAGCTTT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGVKVAKSKEDVIEFANNIIGTR
LVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSRRITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQ
AREVAFALGLKDKQIGQFVKIMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQEN
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKIILADTSVQGVLINIF
GGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKLLDESGLKLISANGLSDAAEKVVAAVKA

Sequences:

>Translated_388_residues
MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGVKVAKSKEDVIEFANNIIGTR
LVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSRRITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQ
AREVAFALGLKDKQIGQFVKIMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQEN
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKIILADTSVQGVLINIF
GGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKLLDESGLKLISANGLSDAAEKVVAAVKA
>Mature_388_residues
MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGVKVAKSKEDVIEFANNIIGTR
LVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSRRITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQ
AREVAFALGLKDKQIGQFVKIMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQEN
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKIILADTSVQGVLINIF
GGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKLLDESGLKLISANGLSDAAEKVVAAVKA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=45.6410256410256, Blast_Score=340, Evalue=2e-93,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=43.2291666666667, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=43.4540389972145, Blast_Score=283, Evalue=2e-76,
Organism=Escherichia coli, GI1786948, Length=387, Percent_Identity=65.1162790697674, Blast_Score=492, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=43.0379746835443, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=44.2159383033419, Blast_Score=320, Evalue=7e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=42.7480916030534, Blast_Score=320, Evalue=2e-88,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=43.5768261964735, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=43.5897435897436, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=43.5897435897436, Blast_Score=301, Evalue=3e-82,
Organism=Drosophila melanogaster, GI281361397, Length=391, Percent_Identity=43.7340153452685, Blast_Score=300, Evalue=8e-82,
Organism=Drosophila melanogaster, GI281361395, Length=391, Percent_Identity=43.7340153452685, Blast_Score=300, Evalue=8e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41530; Mature: 41530

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCHHHCEEECCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVAKSKEDVIEFANNIIGTRLVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSR
EEECCHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEEEEECCCC
RITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVK
EEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHEEECCCHHHHHHHHH
IMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQEN
HHHHHHHHHHCCCEEEEEECCEEECCCCCEEEEEEECCCCCCHHCCCCCHHHHHCCCCCH
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVI
HHHHCHHHCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKIILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHH
LLDESGLKLISANGLSDAAEKVVAAVKA
HHCCCCCEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCHHHCEEECCCHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KVAKSKEDVIEFANNIIGTRLVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSR
EEECCHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEEEEECCCC
RITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVK
EEEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHEEECCCHHHHHHHHH
IMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQEN
HHHHHHHHHHCCCEEEEEECCEEECCCCCEEEEEEECCCCCCHHCCCCCHHHHHCCCCCH
ERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVI
HHHHCHHHCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
EAFKIILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAK
HHHHHHHCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHH
LLDESGLKLISANGLSDAAEKVVAAVKA
HHCCCCCEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA