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The map label for this gene is leuO [H]

Identifier: 213157519

GI number: 213157519

Start: 2293062

End: 2293982

Strand: Direct

Name: leuO [H]

Synonym: AB57_2208

Alternate gene names: 213157519

Gene position: 2293062-2293982 (Clockwise)

Preceding gene: 213157514

Following gene: 213157520

Centisome position: 56.61

GC content: 35.61

Gene sequence:

>921_bases
ATGAATAATATTCATAACCTACATGGTCTAGACTTAAGTTTTTTTCACCGAATTGATATCAATTTATATCCGCTTTTTAT
CGCAATTTATGAGCAAAAAAGTATTTCAAATGCGGCAAGTAGTCTCAATATTACGCAGTCAGCAGCAAGTCATGCTTTGC
AGCGTTTACGGCAGCAACTTGAAGATGATGTATTTATACGTGTAGGTAATAAAATGTCTGCAACGCCTTTTGCAGAACAG
ATTTATCCAACTGTTAAGCAAGCACTTTTAACCATTCAAAACATTAGCCAACAGAAACATGTATTCGACCCAACAAGTTT
AAAAAGCTTAAAAATCGCCGTGCATGACGAAATTGAGCCAATTATTCTTCCAAGGTTGGCTCAACATTTTCAAAATCTTA
ATTTAGATTTGCAGTTTGTGAGTATGAAACTCGATCGAAAACATATTATGGCGGACTTGGCGACACAACAGCTCGATTTC
GTGATTGATCTAGAACAATACTTATCTCCAAAAATTACCTTTGATCATTTGGTCACAGATGAGTTCGTTATTTGCAGCCA
ACTTAAAGAAGTCGATTTAGCTAGTTATATTAATGGACGACACATTGGTGTTTCATCACGCCGTACGGGTGCTTTACTTG
AAGATATTTATTTAAACCAACACCAAAAAATTTCAAGAAATGTATTTATGCGCTGTCAAAACTACTCAACGGCGTTACAA
GTTTTGGGAGCCCAAGTCGATGCAATACTTACCATGCCCCGTATGATTTTGCAGCATTTATCTTATAGCCCTGAGATTCG
GTTACATTCTCTACCTTTTGAGATGACCAATATTAAAATGGGTATGTTTTGGCACGAAGATTTAAGGGATAATTTAAGGC
ATCAATTTTTGCGACATGAAATTATTAAACTTTTTCAGTAA

Upstream 100 bases:

>100_bases
GAGTTCAAACATTCTTTTTCCTTTACATCATTATCTGGTCTTTACATCAACATAACTTGAAACTTAATATGAATGAAATG
ATTTTATTAAATAATGCATC

Downstream 100 bases:

>100_bases
AGCAAATTGATCTACTAAGCTTCTATCGTACAAGGACCAGTAATGAGTAAAGATGAACGGATAATCCAGAATCAGGACAA
CAAAAAAACGATTCGTCATG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNNIHNLHGLDLSFFHRIDINLYPLFIAIYEQKSISNAASSLNITQSAASHALQRLRQQLEDDVFIRVGNKMSATPFAEQ
IYPTVKQALLTIQNISQQKHVFDPTSLKSLKIAVHDEIEPIILPRLAQHFQNLNLDLQFVSMKLDRKHIMADLATQQLDF
VIDLEQYLSPKITFDHLVTDEFVICSQLKEVDLASYINGRHIGVSSRRTGALLEDIYLNQHQKISRNVFMRCQNYSTALQ
VLGAQVDAILTMPRMILQHLSYSPEIRLHSLPFEMTNIKMGMFWHEDLRDNLRHQFLRHEIIKLFQ

Sequences:

>Translated_306_residues
MNNIHNLHGLDLSFFHRIDINLYPLFIAIYEQKSISNAASSLNITQSAASHALQRLRQQLEDDVFIRVGNKMSATPFAEQ
IYPTVKQALLTIQNISQQKHVFDPTSLKSLKIAVHDEIEPIILPRLAQHFQNLNLDLQFVSMKLDRKHIMADLATQQLDF
VIDLEQYLSPKITFDHLVTDEFVICSQLKEVDLASYINGRHIGVSSRRTGALLEDIYLNQHQKISRNVFMRCQNYSTALQ
VLGAQVDAILTMPRMILQHLSYSPEIRLHSLPFEMTNIKMGMFWHEDLRDNLRHQFLRHEIIKLFQ
>Mature_306_residues
MNNIHNLHGLDLSFFHRIDINLYPLFIAIYEQKSISNAASSLNITQSAASHALQRLRQQLEDDVFIRVGNKMSATPFAEQ
IYPTVKQALLTIQNISQQKHVFDPTSLKSLKIAVHDEIEPIILPRLAQHFQNLNLDLQFVSMKLDRKHIMADLATQQLDF
VIDLEQYLSPKITFDHLVTDEFVICSQLKEVDLASYINGRHIGVSSRRTGALLEDIYLNQHQKISRNVFMRCQNYSTALQ
VLGAQVDAILTMPRMILQHLSYSPEIRLHSLPFEMTNIKMGMFWHEDLRDNLRHQFLRHEIIKLFQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=23.9057239057239, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081766, Length=107, Percent_Identity=34.5794392523364, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35497; Mature: 35497

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIHNLHGLDLSFFHRIDINLYPLFIAIYEQKSISNAASSLNITQSAASHALQRLRQQL
CCCCCCCCCCCHHHEEEECCEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
EDDVFIRVGNKMSATPFAEQIYPTVKQALLTIQNISQQKHVFDPTSLKSLKIAVHDEIEP
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCH
IILPRLAQHFQNLNLDLQFVSMKLDRKHIMADLATQQLDFVIDLEQYLSPKITFDHLVTD
HHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCHHHHHCH
EFVICSQLKEVDLASYINGRHIGVSSRRTGALLEDIYLNQHQKISRNVFMRCQNYSTALQ
HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHH
VLGAQVDAILTMPRMILQHLSYSPEIRLHSLPFEMTNIKMGMFWHEDLRDNLRHQFLRHE
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCEEEEEEEHHHHHHHHHHHHHHHH
IIKLFQ
HHHHCC
>Mature Secondary Structure
MNNIHNLHGLDLSFFHRIDINLYPLFIAIYEQKSISNAASSLNITQSAASHALQRLRQQL
CCCCCCCCCCCHHHEEEECCEEEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
EDDVFIRVGNKMSATPFAEQIYPTVKQALLTIQNISQQKHVFDPTSLKSLKIAVHDEIEP
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCH
IILPRLAQHFQNLNLDLQFVSMKLDRKHIMADLATQQLDFVIDLEQYLSPKITFDHLVTD
HHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHEEEHHHHCCCCCCHHHHHCH
EFVICSQLKEVDLASYINGRHIGVSSRRTGALLEDIYLNQHQKISRNVFMRCQNYSTALQ
HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHH
VLGAQVDAILTMPRMILQHLSYSPEIRLHSLPFEMTNIKMGMFWHEDLRDNLRHQFLRHE
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCEEEEEEEHHHHHHHHHHHHHHHH
IIKLFQ
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609; 3519576 [H]