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The map label for this gene is yjjL [H]

Identifier: 213157513

GI number: 213157513

Start: 2286377

End: 2287726

Strand: Direct

Name: yjjL [H]

Synonym: AB57_2202

Alternate gene names: 213157513

Gene position: 2286377-2287726 (Clockwise)

Preceding gene: 213157511

Following gene: 213157514

Centisome position: 56.45

GC content: 40.81

Gene sequence:

>1350_bases
ATGAACCAAAGTAATATCGCTGTTGAAAGGACACAAAAGAAAACCAATGCATATGCATGGTATGTGGTCATACTTTGTAT
GTTGGCCTATATTTTTTCATTTATTGACCGTCAAATTCTAGCGTTGATGATTGAACCCATCAAAGCAGACCTTCAACTTT
CAGATACTCAATTTAGCTTGTTACATGGCCTTGCCTTTTCACTATTCTACGCTGTGATGGGCTTACCATTAGCCTATATT
GCCGACCGTTTTTCCCGACCAAAACTGATTTCAATCGGGATTATTGTCTGGAGCTTAGCAACAGCAACTTGCGGTTTAAG
TAAAAACTTTATTCAACTATTCCTAAGCCGTATGGCTGTGGGCGTTGGTGAAGCAGCTTTATCTCCAGCGGCCTATTCAA
TGTTTAGTGACATGTTTAGTAAAGACAAACTAGGCCGCGCAGTCGGGATCTATTCAATTGGTGCTTTCTTAGGTGGAGGT
ATCGCCTTTTTAGTTGGCGGTTACGTGATTAACCTGCTTAAAGGCGTGACACTCATTGAAGTTCCTTTATTAGGTGCACT
CAAGGCATGGCAAATTGCCTTTTTAGTGGTGGGGTTACCCGGCATTATTATTGGTTTGCTATTTATTTTGACAGTTAAGG
ATCCTGCACGTAAAGGACAGCAGCTCAACCAAAGCGGACAAGTTGACCAAGTTAAATTCACGCAGTGCCTTCAGTTTATC
AAGAAACATGCAAAAACATTTGCTTGTCACTATTTAGGTTTTACCTTTTATGCAATGGCACTCTACAGTCTGACTAGTTG
GACACCAGCATTTTATATTCGTAAGTTTCAACTCGCGCCGACTGAAACAGGCTATATGCTCGGCACTATATTGCTAGTTG
CAAATACTTTAGGCGTGTTTTGTGCAGGATGGCTAAACGACTGGTTTACTAAAAAAGGACGCCAAGATGCACCGATGTTC
ACGGGTGTGATTGGTATTGTTGGCCTGATTATTCCAATTGCATTTTTTACCCAAACAGATCAACTCTGGCTTTCAGTAAC
TTTGCTCATTCCTGCAATGTTCTTTGCCTCCTTCCCACTTGTGATTTCGGCAACAGCATTGCAAATGTTAGCCCCCAACC
AATTTAGAGCACGCCTTTCTGCCCTATTCCTTTTAGTAAGTAACTTAATTGGACTAGGTGTTGGTACAACATTAGTGGCA
ATTATTACAGATAAGGTTTTTGGCAATCCATTAATGGTGGGTTCTTCTTTATCTATTGTGGGTGGTTTGTCCTGTGTACT
GGCTTTGGCTCTACTTTTCAAAGGCTGTAAATCCTTTAGTGAAAGCATGAAGCTTGAAAAATTACATTAA

Upstream 100 bases:

>100_bases
TCATTATTCATTTCAAATGGGGACGTATCAAAAATTTTGAGGATGAATAGAAGCTAGAGATCAATTTCTTTAAAGCGTTT
TATACATAAGGATTAAGTGT

Downstream 100 bases:

>100_bases
TTGAAGCAACAGCCACTTATAAAAACAGGAGTTCCCTTTAAACAATTTAGGGAACACCACACCAATATTTCACAATACGT
AATGCCGAGGACTGGCATAT

Product: general substrate transporter:Major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MNQSNIAVERTQKKTNAYAWYVVILCMLAYIFSFIDRQILALMIEPIKADLQLSDTQFSLLHGLAFSLFYAVMGLPLAYI
ADRFSRPKLISIGIIVWSLATATCGLSKNFIQLFLSRMAVGVGEAALSPAAYSMFSDMFSKDKLGRAVGIYSIGAFLGGG
IAFLVGGYVINLLKGVTLIEVPLLGALKAWQIAFLVVGLPGIIIGLLFILTVKDPARKGQQLNQSGQVDQVKFTQCLQFI
KKHAKTFACHYLGFTFYAMALYSLTSWTPAFYIRKFQLAPTETGYMLGTILLVANTLGVFCAGWLNDWFTKKGRQDAPMF
TGVIGIVGLIIPIAFFTQTDQLWLSVTLLIPAMFFASFPLVISATALQMLAPNQFRARLSALFLLVSNLIGLGVGTTLVA
IITDKVFGNPLMVGSSLSIVGGLSCVLALALLFKGCKSFSESMKLEKLH

Sequences:

>Translated_449_residues
MNQSNIAVERTQKKTNAYAWYVVILCMLAYIFSFIDRQILALMIEPIKADLQLSDTQFSLLHGLAFSLFYAVMGLPLAYI
ADRFSRPKLISIGIIVWSLATATCGLSKNFIQLFLSRMAVGVGEAALSPAAYSMFSDMFSKDKLGRAVGIYSIGAFLGGG
IAFLVGGYVINLLKGVTLIEVPLLGALKAWQIAFLVVGLPGIIIGLLFILTVKDPARKGQQLNQSGQVDQVKFTQCLQFI
KKHAKTFACHYLGFTFYAMALYSLTSWTPAFYIRKFQLAPTETGYMLGTILLVANTLGVFCAGWLNDWFTKKGRQDAPMF
TGVIGIVGLIIPIAFFTQTDQLWLSVTLLIPAMFFASFPLVISATALQMLAPNQFRARLSALFLLVSNLIGLGVGTTLVA
IITDKVFGNPLMVGSSLSIVGGLSCVLALALLFKGCKSFSESMKLEKLH
>Mature_449_residues
MNQSNIAVERTQKKTNAYAWYVVILCMLAYIFSFIDRQILALMIEPIKADLQLSDTQFSLLHGLAFSLFYAVMGLPLAYI
ADRFSRPKLISIGIIVWSLATATCGLSKNFIQLFLSRMAVGVGEAALSPAAYSMFSDMFSKDKLGRAVGIYSIGAFLGGG
IAFLVGGYVINLLKGVTLIEVPLLGALKAWQIAFLVVGLPGIIIGLLFILTVKDPARKGQQLNQSGQVDQVKFTQCLQFI
KKHAKTFACHYLGFTFYAMALYSLTSWTPAFYIRKFQLAPTETGYMLGTILLVANTLGVFCAGWLNDWFTKKGRQDAPMF
TGVIGIVGLIIPIAFFTQTDQLWLSVTLLIPAMFFASFPLVISATALQMLAPNQFRARLSALFLLVSNLIGLGVGTTLVA
IITDKVFGNPLMVGSSLSIVGGLSCVLALALLFKGCKSFSESMKLEKLH

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=257, Percent_Identity=26.4591439688716, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI14042968, Length=257, Percent_Identity=26.4591439688716, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI194239645, Length=260, Percent_Identity=27.3076923076923, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI185136021, Length=321, Percent_Identity=25.2336448598131, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI215490100, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI2367379, Length=349, Percent_Identity=23.2091690544413, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082320, Length=449, Percent_Identity=22.271714922049, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1789152, Length=424, Percent_Identity=20.7547169811321, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193209775, Length=420, Percent_Identity=23.0952380952381, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17539092, Length=472, Percent_Identity=24.364406779661, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17557872, Length=419, Percent_Identity=22.1957040572792, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17864456, Length=447, Percent_Identity=23.0425055928412, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24654039, Length=447, Percent_Identity=23.0425055928412, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24654037, Length=452, Percent_Identity=22.787610619469, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654041, Length=452, Percent_Identity=22.787610619469, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654044, Length=261, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640209, Length=184, Percent_Identity=27.1739130434783, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48958; Mature: 48958

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSNIAVERTQKKTNAYAWYVVILCMLAYIFSFIDRQILALMIEPIKADLQLSDTQFSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHH
LHGLAFSLFYAVMGLPLAYIADRFSRPKLISIGIIVWSLATATCGLSKNFIQLFLSRMAV
HHHHHHHHHHHHHHCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVGEAALSPAAYSMFSDMFSKDKLGRAVGIYSIGAFLGGGIAFLVGGYVINLLKGVTLIE
CCCHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
VPLLGALKAWQIAFLVVGLPGIIIGLLFILTVKDPARKGQQLNQSGQVDQVKFTQCLQFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHCCCCCCCCHHHHHHHHHHH
KKHAKTFACHYLGFTFYAMALYSLTSWTPAFYIRKFQLAPTETGYMLGTILLVANTLGVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHH
CAGWLNDWFTKKGRQDAPMFTGVIGIVGLIIPIAFFTQTDQLWLSVTLLIPAMFFASFPL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VISATALQMLAPNQFRARLSALFLLVSNLIGLGVGTTLVAIITDKVFGNPLMVGSSLSIV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEECCCHHHH
GGLSCVLALALLFKGCKSFSESMKLEKLH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]