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The map label for this gene is qseD [H]

Identifier: 213157270

GI number: 213157270

Start: 2047458

End: 2048354

Strand: Direct

Name: qseD [H]

Synonym: AB57_1958

Alternate gene names: 213157270

Gene position: 2047458-2048354 (Clockwise)

Preceding gene: 213157269

Following gene: 213157271

Centisome position: 50.55

GC content: 33.78

Gene sequence:

>897_bases
ATGAATTTAGAAGTCCGTTGGGTAGAGGATCTCCTCACATTAGAACGTGAACGTTCAATCTCAAAAGCAGCAGAGAAAAG
ATTTATTAGCCAGTCTGCATTTACTCGAAGAATTCAACAAATTGAAGAAATGATTGGTGCTGAAGTCATTATTAGGAACA
ACAAAAACAACATCGAATTTACAGACATTGGTCGAATTTTATTAGTGATGTCTAAAAATATTGAAAAACAGGTAGAGGAG
ACCGCAAAACTAATTAAAAATATTAAAAATGAAATTGAATCGACCATTCGTTTCTGCGTTGTTCATTCTTTAGCCTCTGG
ATTTTTAACTACTTTTTTAAAGAAATTTCCTACACTTATTCGTGATTTAAAAATTGAAATTGTCGCAACGAATAGTGGAG
AAGGCCTGTCTTTGTTAAAAGAAGGTGCTTGTGACTTTATGATTTGCTATGCAGATAAAAGCAATATTAGAAAGGTTGGG
GATGATATTTTAAGTGGTATCAAAATTGCTGAAACGGTTATTGTACCGGTTTCTGCAACTGAACCCGACCATAGCCCGAA
ACATACAATACAAAGTAACTTTGCTCTGCTAGCGTATAGTAAACACGCGTACTTAAGAAAACTGGTGGATCAACTGATTG
AAGGTAAACTTATATATAAAACGTTATATGAAACAGATAATGCCACCAATTTAAAAGAGCTGGTTTTACAAGGTCTAGGG
GTTGCTTGGATTCCAAAAATTAATGTTGAAGAAGATCTTGCAGCTGGAAAATTAGTCATTTTAGACCAACAAGAATATTG
CCTTGCTCAAGATATTTATATCTTCAAAAATAATTTGAGTGATAATAAGTCGGTACAGAAAATATGGAATGGTTTTAAAG
GCCAGCAAGACCTATAA

Upstream 100 bases:

>100_bases
TCCCTATGTTTTATCATTCTTTCTCATCACTAAATTTATTTATGCTACTTCCCAAAAATATCAATTAATAAAATTACAAA
TCTAAAAGGGAATAGATAAG

Downstream 100 bases:

>100_bases
CGTCTACTCATTTGAAATGATGAAGTACACGATATTTATATATAAATTAAGCAAATAAGTAGATTATGCTTTGGTCTTTA
CGATGAAAGGCAGTATAAAG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNLEVRWVEDLLTLERERSISKAAEKRFISQSAFTRRIQQIEEMIGAEVIIRNNKNNIEFTDIGRILLVMSKNIEKQVEE
TAKLIKNIKNEIESTIRFCVVHSLASGFLTTFLKKFPTLIRDLKIEIVATNSGEGLSLLKEGACDFMICYADKSNIRKVG
DDILSGIKIAETVIVPVSATEPDHSPKHTIQSNFALLAYSKHAYLRKLVDQLIEGKLIYKTLYETDNATNLKELVLQGLG
VAWIPKINVEEDLAAGKLVILDQQEYCLAQDIYIFKNNLSDNKSVQKIWNGFKGQQDL

Sequences:

>Translated_298_residues
MNLEVRWVEDLLTLERERSISKAAEKRFISQSAFTRRIQQIEEMIGAEVIIRNNKNNIEFTDIGRILLVMSKNIEKQVEE
TAKLIKNIKNEIESTIRFCVVHSLASGFLTTFLKKFPTLIRDLKIEIVATNSGEGLSLLKEGACDFMICYADKSNIRKVG
DDILSGIKIAETVIVPVSATEPDHSPKHTIQSNFALLAYSKHAYLRKLVDQLIEGKLIYKTLYETDNATNLKELVLQGLG
VAWIPKINVEEDLAAGKLVILDQQEYCLAQDIYIFKNNLSDNKSVQKIWNGFKGQQDL
>Mature_298_residues
MNLEVRWVEDLLTLERERSISKAAEKRFISQSAFTRRIQQIEEMIGAEVIIRNNKNNIEFTDIGRILLVMSKNIEKQVEE
TAKLIKNIKNEIESTIRFCVVHSLASGFLTTFLKKFPTLIRDLKIEIVATNSGEGLSLLKEGACDFMICYADKSNIRKVG
DDILSGIKIAETVIVPVSATEPDHSPKHTIQSNFALLAYSKHAYLRKLVDQLIEGKLIYKTLYETDNATNLKELVLQGLG
VAWIPKINVEEDLAAGKLVILDQQEYCLAQDIYIFKNNLSDNKSVQKIWNGFKGQQDL

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=296, Percent_Identity=27.027027027027, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788296, Length=227, Percent_Identity=22.9074889867841, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33805; Mature: 33805

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEVRWVEDLLTLERERSISKAAEKRFISQSAFTRRIQQIEEMIGAEVIIRNNKNNIEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEH
TDIGRILLVMSKNIEKQVEETAKLIKNIKNEIESTIRFCVVHSLASGFLTTFLKKFPTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDLKIEIVATNSGEGLSLLKEGACDFMICYADKSNIRKVGDDILSGIKIAETVIVPVSAT
HHCEEEEEEECCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCHHHHHEEEEEEECC
EPDHSPKHTIQSNFALLAYSKHAYLRKLVDQLIEGKLIYKTLYETDNATNLKELVLQGLG
CCCCCCCHHHHCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCC
VAWIPKINVEEDLAAGKLVILDQQEYCLAQDIYIFKNNLSDNKSVQKIWNGFKGQQDL
EEEECCCCCHHHHCCCEEEEECCCHHHHHHHHHEEECCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNLEVRWVEDLLTLERERSISKAAEKRFISQSAFTRRIQQIEEMIGAEVIIRNNKNNIEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEH
TDIGRILLVMSKNIEKQVEETAKLIKNIKNEIESTIRFCVVHSLASGFLTTFLKKFPTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDLKIEIVATNSGEGLSLLKEGACDFMICYADKSNIRKVGDDILSGIKIAETVIVPVSAT
HHCEEEEEEECCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCHHHHHEEEEEEECC
EPDHSPKHTIQSNFALLAYSKHAYLRKLVDQLIEGKLIYKTLYETDNATNLKELVLQGLG
CCCCCCCHHHHCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCC
VAWIPKINVEEDLAAGKLVILDQQEYCLAQDIYIFKNNLSDNKSVQKIWNGFKGQQDL
EEEECCCCCHHHHCCCEEEEECCCHHHHHHHHHEEECCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]