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The map label for this gene is cobC [H]

Identifier: 213157203

GI number: 213157203

Start: 1976929

End: 1977507

Strand: Direct

Name: cobC [H]

Synonym: AB57_1886

Alternate gene names: 213157203

Gene position: 1976929-1977507 (Clockwise)

Preceding gene: 213157202

Following gene: 213157204

Centisome position: 48.81

GC content: 39.03

Gene sequence:

>579_bases
TTGCTTAGACATGGCGAAAGCCAGTATAGCCATACTTTACGTGGCCATTTAGATGATGAGTTAACGGCAAAAGGTTGGCA
GCAAATGCAGTCAACTATTGAGCAAGTCACAAACCAGACATGGGATGTCATTGTAAGTTCTTCATTAAAACGTTGTGCTT
GTTTTGCCGAGCAACTGGCCAAAACAGCAGAACTCCCTTTACTTGTAAATCATGACTTAAAAGAAATGTATTTTGGTGAA
TGGGAAGGCGTCTCAACTCAGCAAATTTATGAAAATTCACCCGAATTACTGGCAAACTTTTGGCAAAAACCAAGTCAATA
TTGTCCACCTCGCGCAGAAACATTAAACCAGTTTCAAACAAGGATTCTTAAAGGTTTTCAGGATTTGCTGGGGTATATGC
AAAAGCAAAACTTACAGCATGCTTTAGTTGTTACTCATGGCGGTGTGATTAAGCTATTGGCTTGTTTAGCCAGACAACAG
CCTCTAGATGACTTACTTAAAATGCCGGCAGAGCTTGGAAAATTATATTCACTCGAATTTTCTGAAACAGGTGGTCAATT
AACTTTTAAGTTAAGATAG

Upstream 100 bases:

>100_bases
TTGGCATTGGTTAAAATGGCTTGCGCTTTACATAACCAAATGGCTACCTTCACTCAAGCGGCTGTAAGCGGAAATAAAAT
TGGCTAAATTTAGGATTGAT

Downstream 100 bases:

>100_bases
TAGTTTTATATTTTTATACACTTGTAAGTTATTATTTTTAAAATGTTATTTTAGCCTGTGTAATAGAACTGTCATTGCTA
GTATCTAAGCTATTGGCATT

Product: fructose-2,6-bisphosphatase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLRHGESQYSHTLRGHLDDELTAKGWQQMQSTIEQVTNQTWDVIVSSSLKRCACFAEQLAKTAELPLLVNHDLKEMYFGE
WEGVSTQQIYENSPELLANFWQKPSQYCPPRAETLNQFQTRILKGFQDLLGYMQKQNLQHALVVTHGGVIKLLACLARQQ
PLDDLLKMPAELGKLYSLEFSETGGQLTFKLR

Sequences:

>Translated_192_residues
MLRHGESQYSHTLRGHLDDELTAKGWQQMQSTIEQVTNQTWDVIVSSSLKRCACFAEQLAKTAELPLLVNHDLKEMYFGE
WEGVSTQQIYENSPELLANFWQKPSQYCPPRAETLNQFQTRILKGFQDLLGYMQKQNLQHALVVTHGGVIKLLACLARQQ
PLDDLLKMPAELGKLYSLEFSETGGQLTFKLR
>Mature_192_residues
MLRHGESQYSHTLRGHLDDELTAKGWQQMQSTIEQVTNQTWDVIVSSSLKRCACFAEQLAKTAELPLLVNHDLKEMYFGE
WEGVSTQQIYENSPELLANFWQKPSQYCPPRAETLNQFQTRILKGFQDLLGYMQKQNLQHALVVTHGGVIKLLACLARQQ
PLDDLLKMPAELGKLYSLEFSETGGQLTFKLR

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=173, Percent_Identity=28.9017341040462, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 21985; Mature: 21985

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRHGESQYSHTLRGHLDDELTAKGWQQMQSTIEQVTNQTWDVIVSSSLKRCACFAEQLA
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTAELPLLVNHDLKEMYFGEWEGVSTQQIYENSPELLANFWQKPSQYCPPRAETLNQFQT
HHHCCCEEECCCHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
RILKGFQDLLGYMQKQNLQHALVVTHGGVIKLLACLARQQPLDDLLKMPAELGKLYSLEF
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHCCEE
SETGGQLTFKLR
CCCCCEEEEEEC
>Mature Secondary Structure
MLRHGESQYSHTLRGHLDDELTAKGWQQMQSTIEQVTNQTWDVIVSSSLKRCACFAEQLA
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTAELPLLVNHDLKEMYFGEWEGVSTQQIYENSPELLANFWQKPSQYCPPRAETLNQFQT
HHHCCCEEECCCHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
RILKGFQDLLGYMQKQNLQHALVVTHGGVIKLLACLARQQPLDDLLKMPAELGKLYSLEF
HHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHCCEE
SETGGQLTFKLR
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]