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The map label for this gene is cobT [H]

Identifier: 213157202

GI number: 213157202

Start: 1975860

End: 1976915

Strand: Direct

Name: cobT [H]

Synonym: AB57_1885

Alternate gene names: 213157202

Gene position: 1975860-1976915 (Clockwise)

Preceding gene: 213157201

Following gene: 213157203

Centisome position: 48.78

GC content: 42.23

Gene sequence:

>1056_bases
ATGAACTGGTGGTTACAATCTGTGCAGCAACCTAATTTAGATACAAAACAACAAGCTGAGCAACATCAACTCCAACTTAC
CAAACCTACAGGTGCTTTAGGAGATCTAGAGCAGATTGCAATCACACTTGCCAGTTTACAGTCAAATGCGCATCCACAAG
TTAACCATCCATGGATTACAATTTTTGCAGGTGATCATGGTGTAGTTGAAGAAAATATTTCTGCATATCCCCAAGCTGTT
ACCCGTCAAATGTTGCAAAACTTCACGACGGGTGGTGCAGCAATTAGTGTGCTTGCTAAATATCATCAAGCTCATTTGCA
AGTGATTGACTGCGGTACAGCAGGCGAAGCATACGAATATGCAGGTGTTGAACGTCATTGTATTCGTGCCGGCACAGCAA
ATTTTGCCAAACAAGCTGCAATGAATGCTGACGAGTGCCGTGCTGCCTTAGAGTTAGGGAAAAAAAGTGTAGATACTGCT
AAAGCGAATGGAGCAGATATTTATATTGCGGGTGAAATGGGGATTGGAAATACCTGTTCTGCCTCTGCTTTAGCATGCCT
TTTATTAAATGATACTGCCGAGCAATTGACTGGAGTAGGTACAGGAATTGGTGCCGATCAGTTAAGACATAAAATTGAAG
TAATTGAAAAAGCAATTGAACTTCATCATAAACATGTCATTGGTGATGTCTTCAAAACACTATGTGCTGTAGGTGGTTTG
GAAATTGCGGCAATTGTCGGTGCTTACATTCGCTGTGCGCAGGTGGGTTTACCTGTGATTGTAGACGGTTTTATTAGTTC
TGTAGCCGCTTTATGTGCGATGCGGATGAATCTTCAAGTGCGTGACTGGATGCTTTTTGGTCATCAATCGGCTGAATATG
GACACCGTCGTATTTTACAAGAACTCAATGCTGACCCAATTTTAAAAATGAATTTGCGTTTAGGTGAAGGTAGTGGTGCT
GGCGCTGCTTTGGCATTGGTTAAAATGGCTTGCGCTTTACATAACCAAATGGCTACCTTCACTCAAGCGGCTGTAAGCGG
AAATAAAATTGGCTAA

Upstream 100 bases:

>100_bases
ATGAAGCAGGAAGGCTACATCAGGCTTTAGGACAAATTGCAGATAAAGTTGTGTTTTGTGTGGCTGGTTTTCCAATGATT
TTAAAAGGTGAGAAATAAAA

Downstream 100 bases:

>100_bases
ATTTAGGATTGATTTGCTTAGACATGGCGAAAGCCAGTATAGCCATACTTTACGTGGCCATTTAGATGATGAGTTAACGG
CAAAAGGTTGGCAGCAAATG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNWWLQSVQQPNLDTKQQAEQHQLQLTKPTGALGDLEQIAITLASLQSNAHPQVNHPWITIFAGDHGVVEENISAYPQAV
TRQMLQNFTTGGAAISVLAKYHQAHLQVIDCGTAGEAYEYAGVERHCIRAGTANFAKQAAMNADECRAALELGKKSVDTA
KANGADIYIAGEMGIGNTCSASALACLLLNDTAEQLTGVGTGIGADQLRHKIEVIEKAIELHHKHVIGDVFKTLCAVGGL
EIAAIVGAYIRCAQVGLPVIVDGFISSVAALCAMRMNLQVRDWMLFGHQSAEYGHRRILQELNADPILKMNLRLGEGSGA
GAALALVKMACALHNQMATFTQAAVSGNKIG

Sequences:

>Translated_351_residues
MNWWLQSVQQPNLDTKQQAEQHQLQLTKPTGALGDLEQIAITLASLQSNAHPQVNHPWITIFAGDHGVVEENISAYPQAV
TRQMLQNFTTGGAAISVLAKYHQAHLQVIDCGTAGEAYEYAGVERHCIRAGTANFAKQAAMNADECRAALELGKKSVDTA
KANGADIYIAGEMGIGNTCSASALACLLLNDTAEQLTGVGTGIGADQLRHKIEVIEKAIELHHKHVIGDVFKTLCAVGGL
EIAAIVGAYIRCAQVGLPVIVDGFISSVAALCAMRMNLQVRDWMLFGHQSAEYGHRRILQELNADPILKMNLRLGEGSGA
GAALALVKMACALHNQMATFTQAAVSGNKIG
>Mature_351_residues
MNWWLQSVQQPNLDTKQQAEQHQLQLTKPTGALGDLEQIAITLASLQSNAHPQVNHPWITIFAGDHGVVEENISAYPQAV
TRQMLQNFTTGGAAISVLAKYHQAHLQVIDCGTAGEAYEYAGVERHCIRAGTANFAKQAAMNADECRAALELGKKSVDTA
KANGADIYIAGEMGIGNTCSASALACLLLNDTAEQLTGVGTGIGADQLRHKIEVIEKAIELHHKHVIGDVFKTLCAVGGL
EIAAIVGAYIRCAQVGLPVIVDGFISSVAALCAMRMNLQVRDWMLFGHQSAEYGHRRILQELNADPILKMNLRLGEGSGA
GAALALVKMACALHNQMATFTQAAVSGNKIG

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=334, Percent_Identity=34.4311377245509, Blast_Score=188, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 37412; Mature: 37412

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWWLQSVQQPNLDTKQQAEQHQLQLTKPTGALGDLEQIAITLASLQSNAHPQVNHPWIT
CCCHHHHCCCCCCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEE
IFAGDHGVVEENISAYPQAVTRQMLQNFTTGGAAISVLAKYHQAHLQVIDCGTAGEAYEY
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHH
AGVERHCIRAGTANFAKQAAMNADECRAALELGKKSVDTAKANGADIYIAGEMGIGNTCS
CCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCCCCCCCC
ASALACLLLNDTAEQLTGVGTGIGADQLRHKIEVIEKAIELHHKHVIGDVFKTLCAVGGL
HHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EIAAIVGAYIRCAQVGLPVIVDGFISSVAALCAMRMNLQVRDWMLFGHQSAEYGHRRILQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHEEECCCCHHHHHHHHHH
ELNADPILKMNLRLGEGSGAGAALALVKMACALHNQMATFTQAAVSGNKIG
HCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNWWLQSVQQPNLDTKQQAEQHQLQLTKPTGALGDLEQIAITLASLQSNAHPQVNHPWIT
CCCHHHHCCCCCCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEE
IFAGDHGVVEENISAYPQAVTRQMLQNFTTGGAAISVLAKYHQAHLQVIDCGTAGEAYEY
EEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHH
AGVERHCIRAGTANFAKQAAMNADECRAALELGKKSVDTAKANGADIYIAGEMGIGNTCS
CCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHCHHHHHHCCCCCCEEEEEECCCCCCCCC
ASALACLLLNDTAEQLTGVGTGIGADQLRHKIEVIEKAIELHHKHVIGDVFKTLCAVGGL
HHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EIAAIVGAYIRCAQVGLPVIVDGFISSVAALCAMRMNLQVRDWMLFGHQSAEYGHRRILQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHEEECCCCHHHHHHHHHH
ELNADPILKMNLRLGEGSGAGAALALVKMACALHNQMATFTQAAVSGNKIG
HCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA