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The map label for this gene is ppiD [H]

Identifier: 213157178

GI number: 213157178

Start: 1946857

End: 1948722

Strand: Direct

Name: ppiD [H]

Synonym: AB57_1861

Alternate gene names: 213157178

Gene position: 1946857-1948722 (Clockwise)

Preceding gene: 213157177

Following gene: 213157180

Centisome position: 48.06

GC content: 37.41

Gene sequence:

>1866_bases
ATGGAATCGTTTCGTACAGTCATTAAGGGTTGGCTCGGCAAAGTCCTTTTAGTTTTGTTTTTGACCCCTTTAGCGCTTGT
AGGTATTGAAGGATATTTTAATAGGGGAAACAAGGCAGATGTCGCAAAAACTGTAAATGGACAGGACATATCAAAAAAAG
ACCTTGAAACTTTAACGCAAAGGTATAAAGAACAATATTTAGCTGCTGTAAAGGGTGATGAAAGTTTACTTAATTTACCG
GTAATTCAAGCCAAAGCTCTTGATATATTGGTATCCCGTAATTTGCTCATTCAACAAGCTGAAAAATTAGGTATTTCTTT
AAGCGATGCTCAAATCGAGCAAATGTTAGCTCAGCAGCCAAGTTTGCAAGAAAATGGCCAGTTTTCACAAAAATTATATG
AAAATTATTTGCGTTCGATTGGTATGACAAGCGAAGGCTTAATCGCTAGCTTACGTCAAGATCACGCTTTAAAAATGTTG
ACTTCAACTTTTGCAGATTATTCTTTAGTGAGTAAAGTTGATTTAATGCAAATTGCGAATTTGCAAACTGAACAGCGTAC
ATTGCATTTGGCTAGTATTAAGTTAGACCCTTATAAAGCTGGTTTAACTGCATCGAACCAAGAGGCTACTGATTACTACA
ACAAACATCAGAATGAGTTTAAACAGCCTGCTTCTGTTGATGTAGATTATGTTGTTTTATCTCCGTCTTTAATGGCTAAG
CCAGCTCCAGCCACAGATGCCGAGCTTAAACAAGCTTATGCAAAGTTCGTAGAAACTCAGCAAAAAGATGCTAAACGCAT
AGTGAAACATATCCTTATTACGACAGACGCTCGTGATGATGCGGCAGCTCAAAAACTTGCTAAAGATGTATATGCAAAAA
TTCAGGGTGGACTGTCATTTGCTCAAGCAGCAGCTCAGTTCTCTGAAGATCCAACTTCTAAAACGAAAGGTGGATTAGTT
GAAGCATATGCACCTGGTGTTTTCTCTGATGCATTTGATAAAACTGTTTTAAGCTTGAAAAATGGTCAAATTTCTCAGCC
AGTAAAAACACAATATGGCTATCATATTATTGAAGCGGAGACTCAGGCCAACCAAATTCCTTCATTTGAAGCTGAGAAAC
CACGTTTAATTGCAGAAGTTGAAAAGAATAAAGTGGCCTCTGTTTATTCAGATACTGTAAATAGTTTGAATGAAACGATT
GTTGGTAATGATTCTTTAGATGCTGTTGTACAGCAGGTTAAAGGTACAAAAATCGAATCATTAAATGGTGTAACTTTAGC
TACTCAAAATCCATATTTAAGTGATCCTAACGTAAAAATTAAATTGTTTAATGATGATGTGAAAAATGGCGATCGTAATG
CTTCATCTAATATTCAATTAGCGAACGGAGATACTGTTTGGGTTAAAGTACGTGACTATCATGCGGCTGGTGTTAAACCA
CTTGCCCAAGCAATGAATGAAGTAAAAGCTAAAGTAATTGATGAGAAAGCACGTAAAGCAGCTCAAGCGAAAATCGCTAC
AATGCTGACAGAATTCAAAACTCAGCCAGCTGAACAAGTTGTCGCGAAAAATAAAGTTGCTTTTGAATCAGCGGGTGTAT
TTACTCGTTCACAAGGTTTAAAACGTGCAATTGAGCGTGCAGCATTTAGTGTTCCTGCGCCAAAACCAGGTATGTGGTCT
GTAACTACCGCGAACTTACCAAATGAGTTAGTGGTTGTGGCTGTTTCTAATGTAAATTCAGCTGCTGTTAACGCTATGCC
TGCTGATCAATTGCAACAATTAAAACAGCTTTACCGCCAATCTCGTGGTCAACAGATACTTGAAGATTACAGCGAATACT
TAAAGTCACACGCTAAAATCAAATAA

Upstream 100 bases:

>100_bases
GCGCGTTTTTTATTAAAAATCTGAATTGACCAATATTGCTCATTCATTCATTGTGGTTTTTCAGTTAAAATTCTCCTCGA
AATAAAATATTGGAATACTT

Downstream 100 bases:

>100_bases
AATCTATGTAATAAAAAAAGCGCTTCGGCGCTTTTTTATTATTCATCGAGATTAGTACCAATATAATTTTGTCTATATTG
TTTAGGTGATAAATCAAATA

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MESFRTVIKGWLGKVLLVLFLTPLALVGIEGYFNRGNKADVAKTVNGQDISKKDLETLTQRYKEQYLAAVKGDESLLNLP
VIQAKALDILVSRNLLIQQAEKLGISLSDAQIEQMLAQQPSLQENGQFSQKLYENYLRSIGMTSEGLIASLRQDHALKML
TSTFADYSLVSKVDLMQIANLQTEQRTLHLASIKLDPYKAGLTASNQEATDYYNKHQNEFKQPASVDVDYVVLSPSLMAK
PAPATDAELKQAYAKFVETQQKDAKRIVKHILITTDARDDAAAQKLAKDVYAKIQGGLSFAQAAAQFSEDPTSKTKGGLV
EAYAPGVFSDAFDKTVLSLKNGQISQPVKTQYGYHIIEAETQANQIPSFEAEKPRLIAEVEKNKVASVYSDTVNSLNETI
VGNDSLDAVVQQVKGTKIESLNGVTLATQNPYLSDPNVKIKLFNDDVKNGDRNASSNIQLANGDTVWVKVRDYHAAGVKP
LAQAMNEVKAKVIDEKARKAAQAKIATMLTEFKTQPAEQVVAKNKVAFESAGVFTRSQGLKRAIERAAFSVPAPKPGMWS
VTTANLPNELVVVAVSNVNSAAVNAMPADQLQQLKQLYRQSRGQQILEDYSEYLKSHAKIK

Sequences:

>Translated_621_residues
MESFRTVIKGWLGKVLLVLFLTPLALVGIEGYFNRGNKADVAKTVNGQDISKKDLETLTQRYKEQYLAAVKGDESLLNLP
VIQAKALDILVSRNLLIQQAEKLGISLSDAQIEQMLAQQPSLQENGQFSQKLYENYLRSIGMTSEGLIASLRQDHALKML
TSTFADYSLVSKVDLMQIANLQTEQRTLHLASIKLDPYKAGLTASNQEATDYYNKHQNEFKQPASVDVDYVVLSPSLMAK
PAPATDAELKQAYAKFVETQQKDAKRIVKHILITTDARDDAAAQKLAKDVYAKIQGGLSFAQAAAQFSEDPTSKTKGGLV
EAYAPGVFSDAFDKTVLSLKNGQISQPVKTQYGYHIIEAETQANQIPSFEAEKPRLIAEVEKNKVASVYSDTVNSLNETI
VGNDSLDAVVQQVKGTKIESLNGVTLATQNPYLSDPNVKIKLFNDDVKNGDRNASSNIQLANGDTVWVKVRDYHAAGVKP
LAQAMNEVKAKVIDEKARKAAQAKIATMLTEFKTQPAEQVVAKNKVAFESAGVFTRSQGLKRAIERAAFSVPAPKPGMWS
VTTANLPNELVVVAVSNVNSAAVNAMPADQLQQLKQLYRQSRGQQILEDYSEYLKSHAKIK
>Mature_621_residues
MESFRTVIKGWLGKVLLVLFLTPLALVGIEGYFNRGNKADVAKTVNGQDISKKDLETLTQRYKEQYLAAVKGDESLLNLP
VIQAKALDILVSRNLLIQQAEKLGISLSDAQIEQMLAQQPSLQENGQFSQKLYENYLRSIGMTSEGLIASLRQDHALKML
TSTFADYSLVSKVDLMQIANLQTEQRTLHLASIKLDPYKAGLTASNQEATDYYNKHQNEFKQPASVDVDYVVLSPSLMAK
PAPATDAELKQAYAKFVETQQKDAKRIVKHILITTDARDDAAAQKLAKDVYAKIQGGLSFAQAAAQFSEDPTSKTKGGLV
EAYAPGVFSDAFDKTVLSLKNGQISQPVKTQYGYHIIEAETQANQIPSFEAEKPRLIAEVEKNKVASVYSDTVNSLNETI
VGNDSLDAVVQQVKGTKIESLNGVTLATQNPYLSDPNVKIKLFNDDVKNGDRNASSNIQLANGDTVWVKVRDYHAAGVKP
LAQAMNEVKAKVIDEKARKAAQAKIATMLTEFKTQPAEQVVAKNKVAFESAGVFTRSQGLKRAIERAAFSVPAPKPGMWS
VTTANLPNELVVVAVSNVNSAAVNAMPADQLQQLKQLYRQSRGQQILEDYSEYLKSHAKIK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=658, Percent_Identity=25.531914893617, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68157; Mature: 68157

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFRTVIKGWLGKVLLVLFLTPLALVGIEGYFNRGNKADVAKTVNGQDISKKDLETLTQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHH
RYKEQYLAAVKGDESLLNLPVIQAKALDILVSRNLLIQQAEKLGISLSDAQIEQMLAQQP
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SLQENGQFSQKLYENYLRSIGMTSEGLIASLRQDHALKMLTSTFADYSLVSKVDLMQIAN
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LQTEQRTLHLASIKLDPYKAGLTASNQEATDYYNKHQNEFKQPASVDVDYVVLSPSLMAK
CCHHHHEEEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCC
PAPATDAELKQAYAKFVETQQKDAKRIVKHILITTDARDDAAAQKLAKDVYAKIQGGLSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHH
AQAAAQFSEDPTSKTKGGLVEAYAPGVFSDAFDKTVLSLKNGQISQPVKTQYGYHIIEAE
HHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEEC
TQANQIPSFEAEKPRLIAEVEKNKVASVYSDTVNSLNETIVGNDSLDAVVQQVKGTKIES
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
LNGVTLATQNPYLSDPNVKIKLFNDDVKNGDRNASSNIQLANGDTVWVKVRDYHAAGVKP
CCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCHH
LAQAMNEVKAKVIDEKARKAAQAKIATMLTEFKTQPAEQVVAKNKVAFESAGVFTRSQGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
KRAIERAAFSVPAPKPGMWSVTTANLPNELVVVAVSNVNSAAVNAMPADQLQQLKQLYRQ
HHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHCCCCHHHHHHHHHHHHH
SRGQQILEDYSEYLKSHAKIK
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MESFRTVIKGWLGKVLLVLFLTPLALVGIEGYFNRGNKADVAKTVNGQDISKKDLETLTQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHH
RYKEQYLAAVKGDESLLNLPVIQAKALDILVSRNLLIQQAEKLGISLSDAQIEQMLAQQP
HHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SLQENGQFSQKLYENYLRSIGMTSEGLIASLRQDHALKMLTSTFADYSLVSKVDLMQIAN
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LQTEQRTLHLASIKLDPYKAGLTASNQEATDYYNKHQNEFKQPASVDVDYVVLSPSLMAK
CCHHHHEEEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCC
PAPATDAELKQAYAKFVETQQKDAKRIVKHILITTDARDDAAAQKLAKDVYAKIQGGLSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHH
AQAAAQFSEDPTSKTKGGLVEAYAPGVFSDAFDKTVLSLKNGQISQPVKTQYGYHIIEAE
HHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCEEEEEEC
TQANQIPSFEAEKPRLIAEVEKNKVASVYSDTVNSLNETIVGNDSLDAVVQQVKGTKIES
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
LNGVTLATQNPYLSDPNVKIKLFNDDVKNGDRNASSNIQLANGDTVWVKVRDYHAAGVKP
CCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCEEEEEEECCCCCCCHH
LAQAMNEVKAKVIDEKARKAAQAKIATMLTEFKTQPAEQVVAKNKVAFESAGVFTRSQGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
KRAIERAAFSVPAPKPGMWSVTTANLPNELVVVAVSNVNSAAVNAMPADQLQQLKQLYRQ
HHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCHHHCCCCHHHHHHHHHHHHH
SRGQQILEDYSEYLKSHAKIK
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]