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The map label for this gene is hbpA [H]

Identifier: 213157149

GI number: 213157149

Start: 1917009

End: 1918793

Strand: Direct

Name: hbpA [H]

Synonym: AB57_1832

Alternate gene names: 213157149

Gene position: 1917009-1918793 (Clockwise)

Preceding gene: 213157143

Following gene: 213157150

Centisome position: 47.33

GC content: 37.76

Gene sequence:

>1785_bases
ATGAACTTGAAATTAAAATTTTTTAAGCTCGCCATTTTAAGTCTGGCTATTACATCAGTTCCTTGTGCTTACGCAATTAC
GCCAGCGCAACCAAACAAAATTTTGCATGTTGCCTATGAGGCCCCAGATGATGGTTTCGATATGGTCAAAACCACCAATT
TCTATAGTGCTAGTATTGCTGAGGCAATTTTTGAGCCTTTACTCAAATATGACTATCTAGCGCGTCCATTACAGTTAGTA
CCCAATACTGTAGAAAGCCTGCCCAAAGTGGAACAAGACGGTAAAGTTTATATATTTAAGATTAAGCCGGGTATCTATTT
TACCAATGATCCAGCTTTTAAAGGTAAACGCCGTGAGTTGGTAGCTGAAGACTATGTCTATACAATTAAACGCATTTTAG
ACCCTAAAAATAGAGCGCCTTCTGTTTCTTTTATTGATGGTAAGTTACAAGGTGCCGATACAGTTGTAGCTCAAGCAAAG
AAAACTGGAAAATTTGATTATGCTGCTCCGATTGCTGGAGTTAAAGCTCTTGATCGATACACTCTACAATTTACTTTGAC
TCGCCAAGACTTTAATTTTCCTTATATTCTTGCCTATATTACTTTTGGTGCTGTTGCTAAAGAGGTTGTTGACTATTACG
GTGACCGTATTGGTATGCATCCCGTAGGTACTGGTCCTTATATGTTAAGTAAATATGTACCGAGAAGTAAGGTCGAGTTA
GTTGCTAATCCTGATTATCGTGGTTTTGTCTGGAATTTTAAGTCAACAGGAACACCTTGGGATAACCAACTTGTTAAGGA
AATGTCTGGAAAGAAAATGCCACAAGTTGGCAAGGTGGTGGTCAGTATCATTGAAGAAGAGCAGTCACGATGGTTAGCTT
TTCAGTCTGGACAACTAGACTTTGATAAACTCACAGCGAATGCTGTTCCTCAAGCTTTAGATGGAAATCAGCTTAAAGCT
TCTTTTAAGAAGAGGGGAATTAAGCACTATCCAAATAAGGATCCTGAGATTACCTATACGATGATGAATATGCGGGATCC
AGTGATCGGTGGTTTTAACCCAGAAAAAATAGCGCTTCGTAGAGCAATTACTCTGTCATACAATCAAAAAGAAAGCATAC
AACAAGCTTATAAAAGTCAGGCTGTTAGATCACAAATGTTTATACCTGAAGGTGTAAACGGATATAACCCTAAATATAAA
AGTAGCGTAGGATATAATCCGCTGTTAGCAAATAAACTACTTGATTATTATGGTTATAAAAAAGCGGCTGATGGCTATCG
GACCTTACCAAATGGCAAACCTTTAATTTTAAAAATCAATACAGAAAATAGCTCAGCATCGGTTATTCATTCAGAACTCT
GGAAAAAAAATCTAGATGCGATTGGCATTCGAGCTGACTTTAAGGTAAGTAACTTTGCAGATAACTTAAAAGCCGCTACT
CAATGTAAATATATGATCTGGAGCGGTGCATGGATTGCTGACTATCCTGAAGGAGATAATTTTGCACAATTACTATATGG
ACCAAATGCTGGGCAGGGAAACCATGCTTGTTATCAGTCTAAAACCTATGATGCTCTTTATACTCAGGCCATTCATTTAC
CACCTCAACAACGGCTCCCATATTACGAAAAACTTAACCGTCAGATAGAAGCTGATAATCCTTGGATTATTCATGTAACA
CGAATTCGTAATTGGTTGATACAGCCTCAAGTTCAGGGGTTTAAAGCTCACCCAATGATGAATACAAACTGGCAATATCT
TGATATTACCCCTATTAAAAAATAA

Upstream 100 bases:

>100_bases
TAAATCCTAAATAGGCCTATCTGTTGAAAAAGAACTTTTCTTATGCAGATTTAGATGTTACTCAAAAGGATAATATCTTT
TAAAAACTAATTACGTGGGT

Downstream 100 bases:

>100_bases
TTTTAGATAAAGATCATCATGACCGAAAATTTAAAACAAAAGCTTAAGCACTGTAGTGTCGGCCTATTCTTTGCCGGAAT
GGCTTTAACGGGTTCTATAT

Product: heme-binding protein A

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MNLKLKFFKLAILSLAITSVPCAYAITPAQPNKILHVAYEAPDDGFDMVKTTNFYSASIAEAIFEPLLKYDYLARPLQLV
PNTVESLPKVEQDGKVYIFKIKPGIYFTNDPAFKGKRRELVAEDYVYTIKRILDPKNRAPSVSFIDGKLQGADTVVAQAK
KTGKFDYAAPIAGVKALDRYTLQFTLTRQDFNFPYILAYITFGAVAKEVVDYYGDRIGMHPVGTGPYMLSKYVPRSKVEL
VANPDYRGFVWNFKSTGTPWDNQLVKEMSGKKMPQVGKVVVSIIEEEQSRWLAFQSGQLDFDKLTANAVPQALDGNQLKA
SFKKRGIKHYPNKDPEITYTMMNMRDPVIGGFNPEKIALRRAITLSYNQKESIQQAYKSQAVRSQMFIPEGVNGYNPKYK
SSVGYNPLLANKLLDYYGYKKAADGYRTLPNGKPLILKINTENSSASVIHSELWKKNLDAIGIRADFKVSNFADNLKAAT
QCKYMIWSGAWIADYPEGDNFAQLLYGPNAGQGNHACYQSKTYDALYTQAIHLPPQQRLPYYEKLNRQIEADNPWIIHVT
RIRNWLIQPQVQGFKAHPMMNTNWQYLDITPIKK

Sequences:

>Translated_594_residues
MNLKLKFFKLAILSLAITSVPCAYAITPAQPNKILHVAYEAPDDGFDMVKTTNFYSASIAEAIFEPLLKYDYLARPLQLV
PNTVESLPKVEQDGKVYIFKIKPGIYFTNDPAFKGKRRELVAEDYVYTIKRILDPKNRAPSVSFIDGKLQGADTVVAQAK
KTGKFDYAAPIAGVKALDRYTLQFTLTRQDFNFPYILAYITFGAVAKEVVDYYGDRIGMHPVGTGPYMLSKYVPRSKVEL
VANPDYRGFVWNFKSTGTPWDNQLVKEMSGKKMPQVGKVVVSIIEEEQSRWLAFQSGQLDFDKLTANAVPQALDGNQLKA
SFKKRGIKHYPNKDPEITYTMMNMRDPVIGGFNPEKIALRRAITLSYNQKESIQQAYKSQAVRSQMFIPEGVNGYNPKYK
SSVGYNPLLANKLLDYYGYKKAADGYRTLPNGKPLILKINTENSSASVIHSELWKKNLDAIGIRADFKVSNFADNLKAAT
QCKYMIWSGAWIADYPEGDNFAQLLYGPNAGQGNHACYQSKTYDALYTQAIHLPPQQRLPYYEKLNRQIEADNPWIIHVT
RIRNWLIQPQVQGFKAHPMMNTNWQYLDITPIKK
>Mature_594_residues
MNLKLKFFKLAILSLAITSVPCAYAITPAQPNKILHVAYEAPDDGFDMVKTTNFYSASIAEAIFEPLLKYDYLARPLQLV
PNTVESLPKVEQDGKVYIFKIKPGIYFTNDPAFKGKRRELVAEDYVYTIKRILDPKNRAPSVSFIDGKLQGADTVVAQAK
KTGKFDYAAPIAGVKALDRYTLQFTLTRQDFNFPYILAYITFGAVAKEVVDYYGDRIGMHPVGTGPYMLSKYVPRSKVEL
VANPDYRGFVWNFKSTGTPWDNQLVKEMSGKKMPQVGKVVVSIIEEEQSRWLAFQSGQLDFDKLTANAVPQALDGNQLKA
SFKKRGIKHYPNKDPEITYTMMNMRDPVIGGFNPEKIALRRAITLSYNQKESIQQAYKSQAVRSQMFIPEGVNGYNPKYK
SSVGYNPLLANKLLDYYGYKKAADGYRTLPNGKPLILKINTENSSASVIHSELWKKNLDAIGIRADFKVSNFADNLKAAT
QCKYMIWSGAWIADYPEGDNFAQLLYGPNAGQGNHACYQSKTYDALYTQAIHLPPQQRLPYYEKLNRQIEADNPWIIHVT
RIRNWLIQPQVQGFKAHPMMNTNWQYLDITPIKK

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=545, Percent_Identity=22.7522935779817, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789966, Length=609, Percent_Identity=21.6748768472906, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789397, Length=569, Percent_Identity=22.4956063268893, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787762, Length=417, Percent_Identity=23.2613908872902, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 67355; Mature: 67355

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKLKFFKLAILSLAITSVPCAYAITPAQPNKILHVAYEAPDDGFDMVKTTNFYSASIA
CCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCEEECCCHHHHHH
EAIFEPLLKYDYLARPLQLVPNTVESLPKVEQDGKVYIFKIKPGIYFTNDPAFKGKRREL
HHHHHHHHHHHHHHCHHHHCCHHHHHCCCCCCCCCEEEEEECCCEEECCCCCCCCCHHHH
VAEDYVYTIKRILDPKNRAPSVSFIDGKLQGADTVVAQAKKTGKFDYAAPIAGVKALDRY
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCEE
TLQFTLTRQDFNFPYILAYITFGAVAKEVVDYYGDRIGMHPVGTGPYMLSKYVPRSKVEL
EEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEE
VANPDYRGFVWNFKSTGTPWDNQLVKEMSGKKMPQVGKVVVSIIEEEQSRWLAFQSGQLD
EECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCC
FDKLTANAVPQALDGNQLKASFKKRGIKHYPNKDPEITYTMMNMRDPVIGGFNPEKIALR
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHEEEE
RAITLSYNQKESIQQAYKSQAVRSQMFIPEGVNGYNPKYKSSVGYNPLLANKLLDYYGYK
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCH
KAADGYRTLPNGKPLILKINTENSSASVIHSELWKKNLDAIGIRADFKVSNFADNLKAAT
HHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
QCKYMIWSGAWIADYPEGDNFAQLLYGPNAGQGNHACYQSKTYDALYTQAIHLPPQQRLP
HEEEEEEECCEEEECCCCCCEEEEEECCCCCCCCCCEECCCCHHHHHHHEECCCCHHCCC
YYEKLNRQIEADNPWIIHVTRIRNWLIQPQVQGFKAHPMMNTNWQYLDITPIKK
HHHHHCCEECCCCCEEEEEEHHHHHHCCCCCCCEEECCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MNLKLKFFKLAILSLAITSVPCAYAITPAQPNKILHVAYEAPDDGFDMVKTTNFYSASIA
CCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCCCCCCCEEECCCHHHHHH
EAIFEPLLKYDYLARPLQLVPNTVESLPKVEQDGKVYIFKIKPGIYFTNDPAFKGKRREL
HHHHHHHHHHHHHHCHHHHCCHHHHHCCCCCCCCCEEEEEECCCEEECCCCCCCCCHHHH
VAEDYVYTIKRILDPKNRAPSVSFIDGKLQGADTVVAQAKKTGKFDYAAPIAGVKALDRY
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHCEE
TLQFTLTRQDFNFPYILAYITFGAVAKEVVDYYGDRIGMHPVGTGPYMLSKYVPRSKVEL
EEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEE
VANPDYRGFVWNFKSTGTPWDNQLVKEMSGKKMPQVGKVVVSIIEEEQSRWLAFQSGQLD
EECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCC
FDKLTANAVPQALDGNQLKASFKKRGIKHYPNKDPEITYTMMNMRDPVIGGFNPEKIALR
HHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHEEEE
RAITLSYNQKESIQQAYKSQAVRSQMFIPEGVNGYNPKYKSSVGYNPLLANKLLDYYGYK
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCH
KAADGYRTLPNGKPLILKINTENSSASVIHSELWKKNLDAIGIRADFKVSNFADNLKAAT
HHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
QCKYMIWSGAWIADYPEGDNFAQLLYGPNAGQGNHACYQSKTYDALYTQAIHLPPQQRLP
HEEEEEEECCEEEECCCCCCEEEEEECCCCCCCCCCEECCCCHHHHHHHEECCCCHHCCC
YYEKLNRQIEADNPWIIHVTRIRNWLIQPQVQGFKAHPMMNTNWQYLDITPIKK
HHHHHCCEECCCCCEEEEEEHHHHHHCCCCCCCEEECCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]