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The map label for this gene is kdsB [H]

Identifier: 213157119

GI number: 213157119

Start: 1889439

End: 1889891

Strand: Direct

Name: kdsB [H]

Synonym: AB57_1802

Alternate gene names: 213157119

Gene position: 1889439-1889891 (Clockwise)

Preceding gene: 213157118

Following gene: 213157120

Centisome position: 46.65

GC content: 37.75

Gene sequence:

>453_bases
TTGCCAGCCCAGCTTGTTCAGCAAGTTGCAAAGCTTTTGGTTGATAAGCCAAATTGTTCAATGTCTACATTATGTGAGCC
TATTCATGCGTTGGATGAATTTCAGCGTGATAGTATCGTAAAAGTAGTCATGTCTAAACAAAATGAAGCATTATATTTTA
GTCGTGCAACTATTCCTTATGATCGAGACAGTGCTAAACAAGCTGAACCAACTTTACATAGCCAAGCATTTCGTCATTTA
GGTTTATATGCTTATCGTGTGAGCTTATTACAAGAATATGTTACATGGGAAATGGGTAAACTTGAAAAGCTCGAGAGTCT
TGAGCAATTGCGTGTTTTAGAAAATGGACACCGTATTGCTATTGCTGTAGCAGAAGCGAATTTACCACCAGGTGTTGACA
CTCAAGCAGATCTTGATCGTTTAAATAATATGCCTGTTGAGTCTTTTGAGTAA

Upstream 100 bases:

>100_bases
AGACCATCCATCGGGAACAGATCGTTTAAGTGAAGTTGCTCGTATTAAAGGATGGGATGCCGATGACATTATTGTAAACG
TACAAGGTGATGAGCCATTA

Downstream 100 bases:

>100_bases
GCGTTAATTTAATGAATCAGAATGTGACTTCTAAGGTTTATCCGTGGCAACAGACAATGTGGGAAACGTTAACAACACGT
TTTCCTAATATTGGGCATGG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MPAQLVQQVAKLLVDKPNCSMSTLCEPIHALDEFQRDSIVKVVMSKQNEALYFSRATIPYDRDSAKQAEPTLHSQAFRHL
GLYAYRVSLLQEYVTWEMGKLEKLESLEQLRVLENGHRIAIAVAEANLPPGVDTQADLDRLNNMPVESFE

Sequences:

>Translated_150_residues
MPAQLVQQVAKLLVDKPNCSMSTLCEPIHALDEFQRDSIVKVVMSKQNEALYFSRATIPYDRDSAKQAEPTLHSQAFRHL
GLYAYRVSLLQEYVTWEMGKLEKLESLEQLRVLENGHRIAIAVAEANLPPGVDTQADLDRLNNMPVESFE
>Mature_149_residues
PAQLVQQVAKLLVDKPNCSMSTLCEPIHALDEFQRDSIVKVVMSKQNEALYFSRATIPYDRDSAKQAEPTLHSQAFRHLG
LYAYRVSLLQEYVTWEMGKLEKLESLEQLRVLENGHRIAIAVAEANLPPGVDTQADLDRLNNMPVESFE

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=141, Percent_Identity=44.6808510638298, Blast_Score=121, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 17014; Mature: 16882

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQLVQQVAKLLVDKPNCSMSTLCEPIHALDEFQRDSIVKVVMSKQNEALYFSRATIPY
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
DRDSAKQAEPTLHSQAFRHLGLYAYRVSLLQEYVTWEMGKLEKLESLEQLRVLENGHRIA
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IAVAEANLPPGVDTQADLDRLNNMPVESFE
EEEEECCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PAQLVQQVAKLLVDKPNCSMSTLCEPIHALDEFQRDSIVKVVMSKQNEALYFSRATIPY
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
DRDSAKQAEPTLHSQAFRHLGLYAYRVSLLQEYVTWEMGKLEKLESLEQLRVLENGHRIA
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IAVAEANLPPGVDTQADLDRLNNMPVESFE
EEEEECCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA