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The map label for this gene is gpt [H]

Identifier: 212224966

GI number: 212224966

Start: 1688892

End: 1689356

Strand: Reverse

Name: gpt [H]

Synonym: TON_1815

Alternate gene names: 212224966

Gene position: 1689356-1688892 (Counterclockwise)

Preceding gene: 212224967

Following gene: 212224965

Centisome position: 91.43

GC content: 53.76

Gene sequence:

>465_bases
ATGGACAAGATTTACCTTACCTGGTGGCAGATTGACAGGGCGGTCTTCGCGCTCGCCGAAGAGCTGAGGAAGAAGTTCAT
GCCCGACGTCATAGTCGGCGTCGCTAGGGGCGGCCTCATTCCCGCTGTAATGCTCAGCCACATCCTTGGCGACGTTGACG
TCGAGATCATAGCCGTCAAGTTCTACAAGGATATAGAGGAGCACATGGAGAAACCAGTAGTGACAATACCGCTGCATGGT
TCGCTGAATGGAAAGAGGGTCGTCATCGTCGACGACGTCAGCGACACAGGTAAGACTCTTGAGGTAGTCATAGAGGAAGT
CAAGAAGGCTGGCGCTAGGGAGGTAAAGGTCGCCTGCCTCAGCATGAAGCCCTGGACTAAGGTCGTTCCTGACTTCTATG
TCTTCAGGACCGACCAGTGGATAGTCTTCCCTTGGGAAGAGTTCCCTGTTGTTGTGAGGGAGTGA

Upstream 100 bases:

>100_bases
TTAACGGAGGCTTTTTAAGTCTATATATTTAACTTCTTGCCATCAGACGAAAGCCTTAAATTGAAGGCCTTTCCAACCTG
CGCTATTCGGAGGTGTTAAC

Downstream 100 bases:

>100_bases
GGTTTCTTTTTTTACTTCCAGATAAAAAGTCAGATTCCATAGCCAAAGAGTTTTAAGCTTTCACTTCCAAGAACTTCAAC
GGGTGGTTTTAGTGAAAAAA

Product: xanthine/guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MDKIYLTWWQIDRAVFALAEELRKKFMPDVIVGVARGGLIPAVMLSHILGDVDVEIIAVKFYKDIEEHMEKPVVTIPLHG
SLNGKRVVIVDDVSDTGKTLEVVIEEVKKAGAREVKVACLSMKPWTKVVPDFYVFRTDQWIVFPWEEFPVVVRE

Sequences:

>Translated_154_residues
MDKIYLTWWQIDRAVFALAEELRKKFMPDVIVGVARGGLIPAVMLSHILGDVDVEIIAVKFYKDIEEHMEKPVVTIPLHG
SLNGKRVVIVDDVSDTGKTLEVVIEEVKKAGAREVKVACLSMKPWTKVVPDFYVFRTDQWIVFPWEEFPVVVRE
>Mature_154_residues
MDKIYLTWWQIDRAVFALAEELRKKFMPDVIVGVARGGLIPAVMLSHILGDVDVEIIAVKFYKDIEEHMEKPVVTIPLHG
SLNGKRVVIVDDVSDTGKTLEVVIEEVKKAGAREVKVACLSMKPWTKVVPDFYVFRTDQWIVFPWEEFPVVVRE

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 17609; Mature: 17609

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIYLTWWQIDRAVFALAEELRKKFMPDVIVGVARGGLIPAVMLSHILGDVDVEIIAVK
CCEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEHH
FYKDIEEHMEKPVVTIPLHGSLNGKRVVIVDDVSDTGKTLEVVIEEVKKAGAREVKVACL
HHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEE
SMKPWTKVVPDFYVFRTDQWIVFPWEEFPVVVRE
CCCCCHHHCCCEEEEEECCEEEEECCCCCEEECC
>Mature Secondary Structure
MDKIYLTWWQIDRAVFALAEELRKKFMPDVIVGVARGGLIPAVMLSHILGDVDVEIIAVK
CCEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEHH
FYKDIEEHMEKPVVTIPLHGSLNGKRVVIVDDVSDTGKTLEVVIEEVKKAGAREVKVACL
HHHHHHHHHHCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEE
SMKPWTKVVPDFYVFRTDQWIVFPWEEFPVVVRE
CCCCCHHHCCCEEEEEECCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA