Click here to switch to the map view.

The map label for this gene is fkpB [C]

Identifier: 212224829

GI number: 212224829

Start: 1544291

End: 1544782

Strand: Reverse

Name: fkpB [C]

Synonym: TON_1678

Alternate gene names: 212224829

Gene position: 1544782-1544291 (Counterclockwise)

Preceding gene: 212224831

Following gene: 212224823

Centisome position: 83.61

GC content: 48.17

Gene sequence:

>492_bases
ATGAAAGTAGAAGTTGGAGATTTTGTGGTGTTCAACTACATCGGAAGATTTGAGGATGGAGAAATTTTTGACACGAGTTA
CGAGGATATCGCAAAGGAGAACGAGATATACGTGGAGGAGAGGGAATACGGGCCCCTCGGAGTTAACGTTGGCGTTGGTG
AGATAATACCCGGTCTTGACGAGGCACTTATCGGAATGGGGATTGGTGAGAAGAAGACCATCACCATACCACCCGAAAAA
GGCTACGGCATGCCAAACCCGGAACTAATCATTGAGGTACCCATAGCCGACTTCTCAAGCGTTGGCATAGAGCCCATCGA
GGGTATGTACGTAATGACCGATTCAGGAATAGCCAAGATAGCAAAGGTTGGATCGGATAACGTTACCCTCGACTTCAACC
ACCCGCTCGCGGGCAAGACCCTTGTCTTTGAGGTCGAGATAGTGGACATACAAAAGGTTAAAGAATCAGAGGCCTCCGAT
CTGGAAGTTTGA

Upstream 100 bases:

>100_bases
TTAGCTTGTTATTCTTCTATATATTACCTCGCTTCGTTAATAGAAATCGTTATAAGGGCGTGCGTCCACTCCTACTGAAA
CACTTTTGGAGTTGAAGGAA

Downstream 100 bases:

>100_bases
TGCTCCTTGGAATATTACAACGCCCATTACCACAAGCAGCAGGCTGTATTTAAGGCCTGCTGAGAACTTTCCTTCTCTTA
TAACGCCAATTCCAAGGCCA

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MKVEVGDFVVFNYIGRFEDGEIFDTSYEDIAKENEIYVEEREYGPLGVNVGVGEIIPGLDEALIGMGIGEKKTITIPPEK
GYGMPNPELIIEVPIADFSSVGIEPIEGMYVMTDSGIAKIAKVGSDNVTLDFNHPLAGKTLVFEVEIVDIQKVKESEASD
LEV

Sequences:

>Translated_163_residues
MKVEVGDFVVFNYIGRFEDGEIFDTSYEDIAKENEIYVEEREYGPLGVNVGVGEIIPGLDEALIGMGIGEKKTITIPPEK
GYGMPNPELIIEVPIADFSSVGIEPIEGMYVMTDSGIAKIAKVGSDNVTLDFNHPLAGKTLVFEVEIVDIQKVKESEASD
LEV
>Mature_163_residues
MKVEVGDFVVFNYIGRFEDGEIFDTSYEDIAKENEIYVEEREYGPLGVNVGVGEIIPGLDEALIGMGIGEKKTITIPPEK
GYGMPNPELIIEVPIADFSSVGIEPIEGMYVMTDSGIAKIAKVGSDNVTLDFNHPLAGKTLVFEVEIVDIQKVKESEASD
LEV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI4503727, Length=101, Percent_Identity=38.6138613861386, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI33469985, Length=81, Percent_Identity=41.9753086419753, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI192448443, Length=82, Percent_Identity=39.0243902439024, Blast_Score=64, Evalue=6e-11,
Organism=Escherichia coli, GI1786211, Length=116, Percent_Identity=30.1724137931034, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17788; Mature: 17788

Theoretical pI: Translated: 3.86; Mature: 3.86

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVEVGDFVVFNYIGRFEDGEIFDTSYEDIAKENEIYVEEREYGPLGVNVGVGEIIPGLD
CEEECCCEEEEEECCCCCCCCEECCCHHHHCCCCCEEEEECCCCCEEEECCHHHHCCCCC
EALIGMGIGEKKTITIPPEKGYGMPNPELIIEVPIADFSSVGIEPIEGMYVMTDSGIAKI
HHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCEEH
AKVGSDNVTLDFNHPLAGKTLVFEVEIVDIQKVKESEASDLEV
HHCCCCCEEEEECCCCCCCEEEEEEEEEEEEHHCCCCCCCCCC
>Mature Secondary Structure
MKVEVGDFVVFNYIGRFEDGEIFDTSYEDIAKENEIYVEEREYGPLGVNVGVGEIIPGLD
CEEECCCEEEEEECCCCCCCCEECCCHHHHCCCCCEEEEECCCCCEEEECCHHHHCCCCC
EALIGMGIGEKKTITIPPEKGYGMPNPELIIEVPIADFSSVGIEPIEGMYVMTDSGIAKI
HHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCEEH
AKVGSDNVTLDFNHPLAGKTLVFEVEIVDIQKVKESEASDLEV
HHCCCCCEEEEECCCCCCCEEEEEEEEEEEEHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]