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The map label for this gene is polB [H]

Identifier: 212224794

GI number: 212224794

Start: 1506011

End: 1508116

Strand: Reverse

Name: polB [H]

Synonym: TON_1643

Alternate gene names: 212224794

Gene position: 1508116-1506011 (Counterclockwise)

Preceding gene: 212224795

Following gene: 212224793

Centisome position: 81.63

GC content: 51.23

Gene sequence:

>2106_bases
ATGGGTCTGATTGAGGATTTAATGGCTAACAACTATCTAATCACTCCGTCGGCCTATTACCTCCTTGTTGATGGCTATAA
GAAGGACTTTACTCTCGCTGAGCTCATCAAGTTCGCCAAGGCAAGGGGTACCTTTGTAATAGACTCCACCGTCGCCAGGG
AGTTTCTCATGGAGAAGGGCATGGCTCCATTGGAAAGTTCGATCTCTTCTTCTGCAGAATTCCACCCCCATGTTGAAGAG
CAAACTTCAGAAGATATGGCTTCTGAAGCTGAAATGCTTGTTGAAACGCCTGGAACTGTCGAATCGTCTGCTGTGGATGG
AGAAATACTCGAACTGACAACTGTGGCTGCTGTTCATAGTGCTGACGAAGGAACGTCTATTTCCACTGGAACCTCCTCTG
AAAGCGGGGGTGATATGTCTGAAATGGGCCCGTTGGGGCAAGAAGAGCCCAACTTTTCTGGGGGGGAGAGTTATATTTCC
ACTGGAACTCTGGAGGAATCCCCCCTTATAGGTGACTCTGAATCTGAAACCGAAGTCATGGAGGCCTCCATTTCTGAGGT
TGCTGATGAAACCCTTCCAGTGGAAGGGGGGCTTTCAGTCGAAGAGGCTCCGACTGGAAACGACAATGGCAATGTCCCCA
GCTACGTGAGCAGTGAGGAGGCCGATAACGGCGTCAAGCCGAGGATAGTCTACGGTGACTATGGTGTTCCGATAGCCTAC
GTCGAGGAGGTTCCTGAAGAAGAGAAGAGCTATTCAGTCTATTCTGACTTTAGGATATCTCCAAAGGAAGGCTTCTACTA
CAGGGCCAAAGAGATTCCAGAGGATTATGAAATTGCCTTCGATGTCAAGGACGTCAAGTTCACCATTCCGAAGGCCAAGG
ACGCCCGGGGCAAGGAGGGGGAGATAATAATCAAGGTCTATGCGGACTACTTCAGGAGCAGGCTCAAGAAGATGCGCCGT
ATTCTTCGCGAGAATCCGGAGATAGGCAGTGTGATAGACATAGCCAAGCTAAGTTACGTTAGAACCGATGATGACGTCAC
GATAATCGGCCTCGTGAACTCTAAAAGGGAGACTGCTAAGGGTTTCATGTTCGAGGTTGAGGACAACACGGGAATAATCA
AGGTCTTCATAAACCGCAACAACGAGGACTCGAAGAAGTTCTTCGAGATAATGCCCGACGCTGTGGTGGCCTTCAAGGGT
CGCTACTCTGGAAGGGGCATCTTCTTCGCGGATAAGATTTACCTGCCGGACGTTCCAAAGTTCAAGCGCGAAAAGCCGCC
CCTTGAGGAAAAGGTCTACGCTGTTCTGCTCAGTGACGTCCACGTCGGAAGCAATAAGTTCTGCGAGAAAGCCTTTATGC
GCTTCCTCGAGTGGCTCAACGGAGATGTCAACAACAGGGCCGAGGAGGAGCTCGTGAGCCGGATTAAGTACATGATAATC
GCTGGCGACGTCGTTGATGGCATAGGCATCTATCCCGGCCAGTACAACGAGCTTGCTATTCCTGACATTTTCGATCAGTA
CGAGGCTTTGGCGAACCTCCTCTCCAACGTCCCGGACCATATAACAATGTTTATTGGCCCGGGCAACCACGATGCGGCCA
GAACGGCCCTTCCTCAGCCGGGCTTTTACGAAGAATATGCCAGACCTCTCCTTAAGCTCAAGAACGCGGTCATAATAAGC
AATCCTGCGGTGGTAAAGCTTCATGGCAGGGACTTTCTCATAGCTCACGGAAGGGGGATAGAGGACGTCGTCAGCTTTAT
CCCGAACAGAACCCATCACAGGCCTGCGGAGGCAATGCTCGACCTCCTCAAGCTCCGCCACCTTGCACCAACCTTCGGTG
AGAAGGTGCCAATAGCTCCGGATCCGGAGGATACCCTTGTCATAGAGAGCGTTCCAGACCTCTTCCAGGCCGGCCACGTC
CACGTTATGCAGTATAAGATTTACAACGGCGTCTTTTTGATAAACACCGGCACATGGCAGGCCCAGACGGAGTTCCAGAA
GATGGTGAACATCGTTCCTACCCCTGCAAGGGTTCCAATAATCGATGTGGAAACCGCCCGTTTGAGGGCCGTTGTGCACT
TTGACCAGTACTGTGAGGGTGTTTGA

Upstream 100 bases:

>100_bases
TCAACGTAACTCCTTATAAGGTCAAGAACATATACCGTCATGATCACCAGCTCCAGACGGTGCTCACTATAAGCATGTCC
CGCCAGAGGAGGCTGCTCTG

Downstream 100 bases:

>100_bases
CAATGGCCGAGCTGTATTCTGAAAAAATGAAAGCTTACTTTGAATCTCTCCAGCGCGAGATTGACAGGGCCTACGAGATA
GCGAGAAAGGCCCGCGCTCA

Product: DNA polymerase II small subunit

Products: NA

Alternate protein names: Pol II [H]

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MGLIEDLMANNYLITPSAYYLLVDGYKKDFTLAELIKFAKARGTFVIDSTVAREFLMEKGMAPLESSISSSAEFHPHVEE
QTSEDMASEAEMLVETPGTVESSAVDGEILELTTVAAVHSADEGTSISTGTSSESGGDMSEMGPLGQEEPNFSGGESYIS
TGTLEESPLIGDSESETEVMEASISEVADETLPVEGGLSVEEAPTGNDNGNVPSYVSSEEADNGVKPRIVYGDYGVPIAY
VEEVPEEEKSYSVYSDFRISPKEGFYYRAKEIPEDYEIAFDVKDVKFTIPKAKDARGKEGEIIIKVYADYFRSRLKKMRR
ILRENPEIGSVIDIAKLSYVRTDDDVTIIGLVNSKRETAKGFMFEVEDNTGIIKVFINRNNEDSKKFFEIMPDAVVAFKG
RYSGRGIFFADKIYLPDVPKFKREKPPLEEKVYAVLLSDVHVGSNKFCEKAFMRFLEWLNGDVNNRAEEELVSRIKYMII
AGDVVDGIGIYPGQYNELAIPDIFDQYEALANLLSNVPDHITMFIGPGNHDAARTALPQPGFYEEYARPLLKLKNAVIIS
NPAVVKLHGRDFLIAHGRGIEDVVSFIPNRTHHRPAEAMLDLLKLRHLAPTFGEKVPIAPDPEDTLVIESVPDLFQAGHV
HVMQYKIYNGVFLINTGTWQAQTEFQKMVNIVPTPARVPIIDVETARLRAVVHFDQYCEGV

Sequences:

>Translated_701_residues
MGLIEDLMANNYLITPSAYYLLVDGYKKDFTLAELIKFAKARGTFVIDSTVAREFLMEKGMAPLESSISSSAEFHPHVEE
QTSEDMASEAEMLVETPGTVESSAVDGEILELTTVAAVHSADEGTSISTGTSSESGGDMSEMGPLGQEEPNFSGGESYIS
TGTLEESPLIGDSESETEVMEASISEVADETLPVEGGLSVEEAPTGNDNGNVPSYVSSEEADNGVKPRIVYGDYGVPIAY
VEEVPEEEKSYSVYSDFRISPKEGFYYRAKEIPEDYEIAFDVKDVKFTIPKAKDARGKEGEIIIKVYADYFRSRLKKMRR
ILRENPEIGSVIDIAKLSYVRTDDDVTIIGLVNSKRETAKGFMFEVEDNTGIIKVFINRNNEDSKKFFEIMPDAVVAFKG
RYSGRGIFFADKIYLPDVPKFKREKPPLEEKVYAVLLSDVHVGSNKFCEKAFMRFLEWLNGDVNNRAEEELVSRIKYMII
AGDVVDGIGIYPGQYNELAIPDIFDQYEALANLLSNVPDHITMFIGPGNHDAARTALPQPGFYEEYARPLLKLKNAVIIS
NPAVVKLHGRDFLIAHGRGIEDVVSFIPNRTHHRPAEAMLDLLKLRHLAPTFGEKVPIAPDPEDTLVIESVPDLFQAGHV
HVMQYKIYNGVFLINTGTWQAQTEFQKMVNIVPTPARVPIIDVETARLRAVVHFDQYCEGV
>Mature_700_residues
GLIEDLMANNYLITPSAYYLLVDGYKKDFTLAELIKFAKARGTFVIDSTVAREFLMEKGMAPLESSISSSAEFHPHVEEQ
TSEDMASEAEMLVETPGTVESSAVDGEILELTTVAAVHSADEGTSISTGTSSESGGDMSEMGPLGQEEPNFSGGESYIST
GTLEESPLIGDSESETEVMEASISEVADETLPVEGGLSVEEAPTGNDNGNVPSYVSSEEADNGVKPRIVYGDYGVPIAYV
EEVPEEEKSYSVYSDFRISPKEGFYYRAKEIPEDYEIAFDVKDVKFTIPKAKDARGKEGEIIIKVYADYFRSRLKKMRRI
LRENPEIGSVIDIAKLSYVRTDDDVTIIGLVNSKRETAKGFMFEVEDNTGIIKVFINRNNEDSKKFFEIMPDAVVAFKGR
YSGRGIFFADKIYLPDVPKFKREKPPLEEKVYAVLLSDVHVGSNKFCEKAFMRFLEWLNGDVNNRAEEELVSRIKYMIIA
GDVVDGIGIYPGQYNELAIPDIFDQYEALANLLSNVPDHITMFIGPGNHDAARTALPQPGFYEEYARPLLKLKNAVIISN
PAVVKLHGRDFLIAHGRGIEDVVSFIPNRTHHRPAEAMLDLLKLRHLAPTFGEKVPIAPDPEDTLVIESVPDLFQAGHVH
VMQYKIYNGVFLINTGTWQAQTEFQKMVNIVPTPARVPIIDVETARLRAVVHFDQYCEGV

Specific function: Possesses two activities:a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase [H]

COG id: COG1311

COG function: function code L; Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase delta/II small subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007185
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR011149 [H]

Pfam domain/function: PF04042 DNA_pol_E_B; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 77915; Mature: 77784

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLIEDLMANNYLITPSAYYLLVDGYKKDFTLAELIKFAKARGTFVIDSTVAREFLMEKG
CCHHHHHHHCCEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCC
MAPLESSISSSAEFHPHVEEQTSEDMASEAEMLVETPGTVESSAVDGEILELTTVAAVHS
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHC
ADEGTSISTGTSSESGGDMSEMGPLGQEEPNFSGGESYISTGTLEESPLIGDSESETEVM
CCCCCEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHH
EASISEVADETLPVEGGLSVEEAPTGNDNGNVPSYVSSEEADNGVKPRIVYGDYGVPIAY
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHH
VEEVPEEEKSYSVYSDFRISPKEGFYYRAKEIPEDYEIAFDVKDVKFTIPKAKDARGKEG
HHHCCCCHHCCEEECCEEECCCCCCEEECCCCCCCCEEEEEEEEEEEECCCCCCCCCCCC
EIIIKVYADYFRSRLKKMRRILRENPEIGSVIDIAKLSYVRTDDDVTIIGLVNSKRETAK
CEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEECCCCEEEEEEECCCCHHCC
GFMFEVEDNTGIIKVFINRNNEDSKKFFEIMPDAVVAFKGRYSGRGIFFADKIYLPDVPK
CEEEEEECCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCCCCC
FKREKPPLEEKVYAVLLSDVHVGSNKFCEKAFMRFLEWLNGDVNNRAEEELVSRIKYMII
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
AGDVVDGIGIYPGQYNELAIPDIFDQYEALANLLSNVPDHITMFIGPGNHDAARTALPQP
ECCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCCC
GFYEEYARPLLKLKNAVIISNPAVVKLHGRDFLIAHGRGIEDVVSFIPNRTHHRPAEAML
CCHHHHHHHHHHHCCEEEECCCCEEEECCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHH
DLLKLRHLAPTFGEKVPIAPDPEDTLVIESVPDLFQAGHVHVMQYKIYNGVFLINTGTWQ
HHHHHHHHCCHHCCCCCCCCCCCCCEEECCCHHHHHCCCEEEEEEEEECCEEEEECCCCC
AQTEFQKMVNIVPTPARVPIIDVETARLRAVVHFDQYCEGV
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHEEHHHHHCCC
>Mature Secondary Structure 
GLIEDLMANNYLITPSAYYLLVDGYKKDFTLAELIKFAKARGTFVIDSTVAREFLMEKG
CHHHHHHHCCEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCC
MAPLESSISSSAEFHPHVEEQTSEDMASEAEMLVETPGTVESSAVDGEILELTTVAAVHS
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHC
ADEGTSISTGTSSESGGDMSEMGPLGQEEPNFSGGESYISTGTLEESPLIGDSESETEVM
CCCCCEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHH
EASISEVADETLPVEGGLSVEEAPTGNDNGNVPSYVSSEEADNGVKPRIVYGDYGVPIAY
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHH
VEEVPEEEKSYSVYSDFRISPKEGFYYRAKEIPEDYEIAFDVKDVKFTIPKAKDARGKEG
HHHCCCCHHCCEEECCEEECCCCCCEEECCCCCCCCEEEEEEEEEEEECCCCCCCCCCCC
EIIIKVYADYFRSRLKKMRRILRENPEIGSVIDIAKLSYVRTDDDVTIIGLVNSKRETAK
CEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEEEECCCCEEEEEEECCCCHHCC
GFMFEVEDNTGIIKVFINRNNEDSKKFFEIMPDAVVAFKGRYSGRGIFFADKIYLPDVPK
CEEEEEECCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCCCCC
FKREKPPLEEKVYAVLLSDVHVGSNKFCEKAFMRFLEWLNGDVNNRAEEELVSRIKYMII
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
AGDVVDGIGIYPGQYNELAIPDIFDQYEALANLLSNVPDHITMFIGPGNHDAARTALPQP
ECCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCCC
GFYEEYARPLLKLKNAVIISNPAVVKLHGRDFLIAHGRGIEDVVSFIPNRTHHRPAEAML
CCHHHHHHHHHHHCCEEEECCCCEEEECCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHH
DLLKLRHLAPTFGEKVPIAPDPEDTLVIESVPDLFQAGHVHVMQYKIYNGVFLINTGTWQ
HHHHHHHHCCHHCCCCCCCCCCCCCEEECCCHHHHHCCCEEEEEEEEECCEEEEECCCCC
AQTEFQKMVNIVPTPARVPIIDVETARLRAVVHFDQYCEGV
HHHHHHHHHHCCCCCCCCEEEECCHHHHHHHEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]