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The map label for this gene is cdc6

Identifier: 212224795

GI number: 212224795

Start: 1508116

End: 1509363

Strand: Reverse

Name: cdc6

Synonym: TON_1644

Alternate gene names: 212224795

Gene position: 1509363-1508116 (Counterclockwise)

Preceding gene: 212224796

Following gene: 212224794

Centisome position: 81.69

GC content: 50.96

Gene sequence:

>1248_bases
ATGGACGACAATTACCTTGATTCAATCTTCGAGAAGTATCTTCATGCCAAGAAGATTTTCAAGAATAAGGAGGTTTTAAG
GCATAGCTATACGCCCAGAGAGCTTCCTCACAGGCGTGAACAGATTGAGAACCTTGCGCACATTCTCGTTCCGGTTCTTA
GAGGTGAAACTCCTTCCAACGTTTTCGTCTACGGCAAAACCGGTACTGGTAAGACCGTCACCATAAAGTTCGTCACAGAG
GAGCTGAAGAAGATATCCCAAAAGTACAACGTTCCCGTTGATGTTATCTATGTCAACTGTGAGATAGTCGACACACAGTA
CCGTGTTCTTGCCAACATAGTGAACCACTTCCGCGAGGAGAGTGGCGTTGAAGTTCCGCTCGTAGGATGGCCGACCGATG
AGGTGTACTCCAAGCTCAAGGCGGTCATAGATGCCAAAGAGCGCTTCGTCATCATAGTCCTCGATGAGATTGACAAACTC
ATCAAAAAGAGCGGTGACGATATTCTTTACTCTCTCACGAGGATAAACACCGAACTTCACCGGGCGAAGGTTAGCATAAT
TGGCATATCCAACGACCTCAAGTTCAAGGACTACCTGGACCCGCGCGTTCTTTCAAGTCTAAGCGAGGAGGAGGTTGTCT
TCCCACCTTACGACGCCAATCAGCTGCGGGATATACTCATGCAGCGTGCTAAGGATGCCTTTAACGAAGGTGTTCTCGAT
GACGGTGTAGTTCCCCTCTGTGCTGCCTTGGCAGCCCGCGAGCACGGTGATGCAAGGCGCGCCCTCGACCTGCTCCGCGT
CGCTGGAGAAATAGCCGAGCGCGAAGGGGCGAGCAAGGTAACCGAGCGCCACGTCTGGAAGGCCCAAGAGAAGATAGAGC
AGGACACCATGGAGGAGGTCATAAAGACCCTTCCGCTCCACTCAAAGGTTCTCCTCTATGCTATCGTTCTCCTGGACGAG
AACGGCGAGCTGCCCGCAAACACTGGCGACGTCTATTCTGTCTACAAGTCCCTCTGCGACCACATAGACCTTGAACCGCT
AACTCAGAGGCGCGTGAGTGATTTAATAAATGAACTAGATATGCTCGGCATCATAAACGCCAAGGTCGTCAGCAAGGGCC
GCTATGGTAGAACCAAGGAGATAAGGCTCAACGTAACTCCTTATAAGGTCAAGAACATATACCGTCATGATCACCAGCTC
CAGACGGTGCTCACTATAAGCATGTCCCGCCAGAGGAGGCTGCTCTGA

Upstream 100 bases:

>100_bases
AGTTATTGTCTTTAAAATTGTCATACGTTCCAACTGTGATTCGGAGCTCTGTACAATAATCACGGCTGGAGCTGGATTTC
CAGTGGAATGGGTGGTGCTG

Downstream 100 bases:

>100_bases
TGGGTCTGATTGAGGATTTAATGGCTAACAACTATCTAATCACTCCGTCGGCCTATTACCTCCTTGTTGATGGCTATAAG
AAGGACTTTACTCTCGCTGA

Product: cell division control protein 6

Products: NA

Alternate protein names: CDC6 homolog

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSNVFVYGKTGTGKTVTIKFVTE
ELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREESGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKL
IKKSGDDILYSLTRINTELHRAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLD
DGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEVIKTLPLHSKVLLYAIVLLDE
NGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQL
QTVLTISMSRQRRLL

Sequences:

>Translated_415_residues
MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSNVFVYGKTGTGKTVTIKFVTE
ELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREESGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKL
IKKSGDDILYSLTRINTELHRAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLD
DGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEVIKTLPLHSKVLLYAIVLLDE
NGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQL
QTVLTISMSRQRRLL
>Mature_415_residues
MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSNVFVYGKTGTGKTVTIKFVTE
ELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREESGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKL
IKKSGDDILYSLTRINTELHRAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLD
DGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEVIKTLPLHSKVLLYAIVLLDE
NGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELDMLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQL
QTVLTISMSRQRRLL

Specific function: Might be involved in the initiation of DNA replication

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family

Homologues:

Organism=Homo sapiens, GI4502703, Length=401, Percent_Identity=25.4364089775561, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI299890795, Length=367, Percent_Identity=24.7956403269755, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI299890793, Length=367, Percent_Identity=24.7956403269755, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI31795544, Length=367, Percent_Identity=24.7956403269755, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555708, Length=373, Percent_Identity=27.6139410187668, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506005, Length=318, Percent_Identity=24.2138364779874, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355681, Length=419, Percent_Identity=23.3890214797136, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17137456, Length=297, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDC6_THEON (B6YUE9)

Other databases:

- EMBL:   CP000855
- RefSeq:   YP_002308031.1
- GeneID:   7018684
- GenomeReviews:   CP000855_GR
- KEGG:   ton:TON_1644
- HOGENOM:   HBG553472
- OMA:   ATISFPK
- ProtClustDB:   PRK00411
- HAMAP:   MF_01407
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10763:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR02928

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C

EC number: NA

Molecular weight: Translated: 47541; Mature: 47541

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
VFVYGKTGTGKTVTIKFVTEELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREE
EEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHH
SGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKLIKKSGDDILYSLTRINTELH
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHH
RAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLD
HEEEEEEEECCCCCHHHCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCC
DGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEV
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IKTLPLHSKVLLYAIVLLDENGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELD
HHHCCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQLQTVLTISMSRQRRLL
HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDDNYLDSIFEKYLHAKKIFKNKEVLRHSYTPRELPHRREQIENLAHILVPVLRGETPSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
VFVYGKTGTGKTVTIKFVTEELKKISQKYNVPVDVIYVNCEIVDTQYRVLANIVNHFREE
EEEEECCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHH
SGVEVPLVGWPTDEVYSKLKAVIDAKERFVIIVLDEIDKLIKKSGDDILYSLTRINTELH
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHH
RAKVSIIGISNDLKFKDYLDPRVLSSLSEEEVVFPPYDANQLRDILMQRAKDAFNEGVLD
HEEEEEEEECCCCCHHHCCCHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCC
DGVVPLCAALAAREHGDARRALDLLRVAGEIAEREGASKVTERHVWKAQEKIEQDTMEEV
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IKTLPLHSKVLLYAIVLLDENGELPANTGDVYSVYKSLCDHIDLEPLTQRRVSDLINELD
HHHCCCCHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MLGIINAKVVSKGRYGRTKEIRLNVTPYKVKNIYRHDHQLQTVLTISMSRQRRLL
HHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA